J M Cunningham

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 1989 7.64
2 Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 1991 5.40
3 Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell 2000 4.88
4 Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem 1992 4.88
5 Biochemical evidence that patched is the Hedgehog receptor. Nature 1996 4.53
6 Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res 1998 3.36
7 Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat Genet 2000 3.33
8 Characterization of a human colon/lung carcinoma oncogene. Nature 1983 3.26
9 Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution. Science 1997 3.13
10 The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell 1983 3.00
11 Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res 1996 2.89
12 Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses. J Virol 1993 2.77
13 Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Cell 1992 2.67
14 The regulated expression of erythropoietin by two human hepatoma cell lines. Proc Natl Acad Sci U S A 1987 2.51
15 The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet 1995 2.30
16 Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1. Nat Genet 1999 2.28
17 Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood 1999 2.14
18 Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron 2000 2.04
19 Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens. EMBO J 1998 1.83
20 Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. Hum Mol Genet 1996 1.76
21 Identification of a receptor-binding pocket on the envelope protein of friend murine leukemia virus. J Virol 1999 1.75
22 Evidence for a prostate cancer-susceptibility locus on chromosome 20. Am J Hum Genet 2000 1.69
23 Human cells infected with retrovirus vectors acquire an endogenous murine provirus. J Virol 1990 1.65
24 Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. Br J Cancer 2009 1.54
25 Allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome. Bone Marrow Transplant 2001 1.52
26 Characterization of the third member of the MCAT family of cationic amino acid transporters. Identification of a domain that determines the transport properties of the MCAT proteins. J Biol Chem 1993 1.49
27 Neural basis of endogenous and exogenous spatial orienting. A functional MRI study. J Cogn Neurosci 1999 1.42
28 In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1. J Virol 1997 1.41
29 Modular organization of the Friend murine leukemia virus envelope protein underlies the mechanism of infection. Proc Natl Acad Sci U S A 2001 1.37
30 Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4. Nat Neurosci 2001 1.37
31 Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol 1999 1.33
32 Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry 1997 1.33
33 Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver. J Biol Chem 1993 1.32
34 SLC6A4 variation and citalopram response. Am J Med Genet B Neuropsychiatr Genet 2009 1.32
35 N-linked glycosylation of the receptor for murine ecotropic retroviruses is altered in virus-infected cells. J Biol Chem 1993 1.32
36 Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. EMBO J 1995 1.30
37 Higher risk of mismatch repair-deficient colorectal cancer in alpha(1)-antitrypsin deficiency carriers and cigarette smokers. Mol Genet Metab 2000 1.28
38 Outcomes of transplantation with matched-sibling and unrelated-donor bone marrow in children with leukaemia. Lancet 1997 1.25
39 Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4. Mol Cell Biol 2000 1.24
40 Role of HPC2/ELAC2 in hereditary prostate cancer. Cancer Res 2001 1.24
41 A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. J Thromb Haemost 2012 1.23
42 The gene for HMSN2C maps to 12q23-24: a region of neuromuscular disorders. Neurology 2003 1.22
43 HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res 2000 1.20
44 Receptor binding transforms the surface subunit of the mammalian C-type retrovirus envelope protein from an inhibitor to an activator of fusion. J Virol 2001 1.19
45 Genetic variation within the anticoagulant, procoagulant, fibrinolytic and innate immunity pathways as risk factors for venous thromboembolism. J Thromb Haemost 2011 1.19
46 Minus-strand DNA is present within murine type C ecotropic retroviruses prior to infection. J Virol 1993 1.14
47 The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the alpha- and beta-globin gene loci in an erythroid cell line. Proc Natl Acad Sci U S A 1997 1.12
48 Mapping of semantic, phonological, and orthographic verbal working memory in normal adults with functional magnetic resonance imaging. Neuropsychology 1999 1.11
49 Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q. Am J Hum Genet 2003 1.10
50 Anemia and perinatal death result from loss of the murine ecotropic retrovirus receptor mCAT-1. Genes Dev 1997 1.10
51 Reduced COX-2 protein in colorectal cancer with defective mismatch repair. Cancer Res 1998 1.09
52 Alpha-synuclein, pesticides, and Parkinson disease: a case-control study. Neurology 2008 1.07
53 Cytokines and insulin induce cationic amino acid transporter (CAT) expression in cardiac myocytes. Regulation of L-arginine transport and no production by CAT-1, CAT-2A, and CAT-2B. J Biol Chem 1996 1.05
54 The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14. Genomics 1992 1.04
55 Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression. Mol Cell Biol 1993 1.04
56 Nitric oxide donors decrease the function and survival of human pancreatic islets. Mol Cell Endocrinol 1996 1.04
57 Distribution of ten laminin chains in dystrophic and regenerating muscles. Neuromuscul Disord 1999 1.04
58 Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an 'adult' acetylcholine receptor subunit. Development 1997 1.04
59 A stable long-term hepatocyte culture system for studies of physiologic processes: cytokine stimulation of the acute phase response in rat and human hepatocytes. Biotechnol Prog 1992 1.03
60 Functional MRI evidence for subcortical participation in conceptual reasoning skills. Neuroreport 1997 1.01
61 Dimethyl sulphoxide induces a reduced growth rate, altered cell morphology and increased epidermal-growth-factor binding in Hep G2 cells. Biochem J 1991 0.99
62 Autoimmune pathogenesis of paraneoplastic neurological syndromes. Crit Rev Neurobiol 1987 0.99
63 Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation. Int J Oncol 1999 0.98
64 To bedlam and back. J Psychosoc Nurs Ment Health Serv 1986 0.98
65 Targeted disruption of the CP2 gene, a member of the NTF family of transcription factors. J Biol Chem 2000 0.96
66 Novel pattern of P53 mutation in breast cancers from Austrian women. J Clin Invest 1995 0.95
67 Acetylcholine receptors in small cell carcinomas. J Neurochem 1985 0.95
68 High frequency of p53 gene mutations in primary breast cancers in Japanese women, a low-incidence population. Br J Cancer 1996 0.94
69 Identification of two novel regulatory elements within the 5'-untranslated region of the human A gamma-globin gene. J Biol Chem 1995 0.94
70 Effects of late gestational high-fat diet on body weight, metabolic regulation and adipokine expression in offspring. Int J Obes (Lond) 2013 0.94
71 Retroviral infection and expression of cationic amino acid transporters in rodent hepatocytes. J Virol 1993 0.94
72 SPTLC1 and RAB7 mutation analysis in dominantly inherited and idiopathic sensory neuropathies. J Neurol Neurosurg Psychiatry 2005 0.92
73 Myelin protein zero mutation His39Pro: hereditary motor and sensory neuropathy with variable onset, hearing loss, restless legs and multiple sclerosis. J Neurol Neurosurg Psychiatry 2006 0.92
74 Hemorrhagic cystitis after allogeneic bone marrow transplantation in children: clinical characteristics and outcome. Biol Blood Marrow Transplant 2003 0.89
75 A prospective trial of midwest breast cancer patients: a p53 gene mutation is the most important predictor of adverse outcome. Int J Cancer 2000 0.88
76 Functional correction of T cells derived from patients with the Wiskott-Aldrich syndrome (WAS) by transduction with an oncoretroviral vector encoding the WAS protein. Gene Ther 2003 0.88
77 Encephalopathy in pediatric patients after allogeneic hematopoietic stem cell transplantation is associated with a poor prognosis. Bone Marrow Transplant 2004 0.87
78 The human erythroid-specific transcription factor EKLF localizes to chromosome 19p13.12-p13.13. Genomics 1997 0.87
79 Genetic variation in glutathione metabolism and DNA repair genes predicts survival of small-cell lung cancer patients. Ann Oncol 2010 0.87
80 Effective donor lymphohematopoietic reconstitution after haploidentical CD34+-selected hematopoietic stem cell transplantation in children with refractory severe aplastic anemia. Bone Marrow Transplant 2004 0.86
81 Neurite outgrowth on cryostat sections of innervated and denervated skeletal muscle. J Cell Biol 1987 0.86
82 Molecular mechanisms of hemoglobin switching. Int J Biochem Cell Biol 1996 0.85
83 The N-ras oncogene assigned to the short arm of human chromosome 1. Nucleic Acids Res 1983 0.85
84 A search for germline APC mutations in early onset colorectal cancer or familial colorectal cancer with normal DNA mismatch repair. Genes Chromosomes Cancer 2001 0.84
85 Cytokines and nitric oxide inhibit the enzyme activity of catalase but not its protein or mRNA expression in insulin-producing cells. J Mol Endocrinol 2003 0.84
86 Arginase expression and modulation of IL-1beta-induced nitric oxide generation in rat and human islets of Langerhans. Nitric Oxide 2002 0.83
87 Analysis of the prostate cancer-susceptibility locus HPC20 in 172 families affected by prostate cancer. Am J Hum Genet 2001 0.83
88 Identification of Id2 as a globin regulatory protein by representational difference analysis of K562 cells induced to express gamma-globin with a fungal compound. Mol Cell Biol 1999 0.83
89 Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability. Biochem Pharmacol 1995 0.83
90 Tumor necrosis factor-alpha and interferon-gamma inhibit insulin secretion and cause DNA damage in unweaned-rat islets. Extent of nitric oxide involvement. Diabetes 1996 0.83
91 Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion. Diabetologia 1993 0.82
92 The Connecticut State Department of Health Mental Hygiene Program. Am J Public Health Nations Health 1942 0.81
93 The inducible nitric oxide synthase gene, Nos2, maps to mouse chromosome 11. Mamm Genome 1994 0.81
94 Use of the comet assay to investigate possible interactions of nitric oxide and reactive oxygen species in the induction of DNA damage and inhibition of function in an insulin-secreting cell line. Mutat Res 1997 0.80
95 Gene transfer into human hemopoietic progenitor cells. Br Med Bull 1995 0.79
96 Allogeneic bone marrow transplantation in children failing prior autologous bone marrow transplantation. Bone Marrow Transplant 2001 0.79
97 No fumarate hydratase (FH) mutations in hereditary prostate cancer. J Med Genet 2003 0.79
98 Maximal activity of an erythroid-specific enhancer requires the presence of specific protein binding sites in linked promoters. J Biol Chem 1998 0.79
99 Characterization of a putative nitric oxide synthase in the neuromuscular system of the parasitic nematode, Ascaris suum. Parasitology 2001 0.79
100 Glucose transporter Glut3 is targeted to secretory vesicles in neurons and PC12 cells. J Biol Chem 1999 0.79
101 Is re-revascularization clinically beneficial? Am J Surg 1981 0.79
102 Improved cerebrovascular patency following therapy in patients with sickle cell disease: initial results in 4 patients who received HLA-identical hematopoietic stem cell allografts. Ann Neurol 2001 0.78
103 Understanding fetal globin gene expression: a step towards effective HbF reactivation in haemoglobinopathies. Br J Haematol 1998 0.78
104 Allogeneic bone marrow transplantation for children with histiocytic disorders: use of TBI and omission of etoposide in the conditioning regimen. Bone Marrow Transplant 2003 0.78
105 Ras oncogenes in human tumours: identification, mechanism of activation and cooperative role in transformation. IARC Sci Publ 1985 0.78
106 Transforming growth factor beta 1 prevents cytokine-mediated inhibitory effects and induction of nitric oxide synthase in the RINm5F insulin-containing beta-cell line. J Endocrinol 1997 0.78
107 Interleukin-1beta-induced nitric oxide production and inhibition of insulin secretion in rat islets of langerhans is dependent upon the nitric oxide synthase cofactor tetrahidrobiopterin. Cytokine 2002 0.77
108 Use of double marking with retroviral vectors to determine rate of reconstitution of untreated and cytokine expanded CD34+ selected marrow cells in patients undergoing autologous bone marrow transplantation. Hum Gene Ther 1996 0.77
109 Development of high-titer retroviral producer cell lines by using Cre-mediated recombination. J Virol 1997 0.77
110 Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: relation to nitric oxide production. Biochem Soc Trans 1994 0.77
111 Immunotherapy with interleukin 2 after ABMT in AML. Bone Marrow Transplant 1993 0.77
112 Insulitis and mechanisms of disease resistance: studies in an animal model of insulin dependent diabetes mellitus. J Mol Med (Berl) 1999 0.77
113 Nitric oxide rather than superoxide or peroxynitrite inhibits insulin secretion and causes DNA damage in HIT-T15 cells. Adv Exp Med Biol 1997 0.76
114 Regulation of interleukin-1-beta-stimulated inducible nitric oxide synthase expression in cultured vascular smooth muscle cells by hemostatic proteins. Biochem Pharmacol 1996 0.75
115 Skeletonization of internal thoracic artery grafts. J Thorac Cardiovasc Surg 1996 0.75
116 Thrombocytopenia--radial aplasia (TAR) syndrome with associated immune thrombocytopenia. Postgrad Med J 1989 0.75
117 Developmental regulation of the human beta-globin cluster. Aust N Z J Med 1995 0.75
118 An integrated somatic cell hybrid, YAC, and BAC map of the Rmc1 region of mouse chromosome 1. Genomics 1999 0.75
119 Vector development: a major obstacle in human gene therapy. Ann Med 1998 0.75
120 Prevention of experimental allergic neuritis in the Lewis rat with bovine P2 protein. Brain Res 1983 0.75
121 J. Franklin Robinson, M.D., 1910-1966. J Am Acad Child Psychiatry 1967 0.75
122 Impact of multiple-family therapy approach on a parallel latency-age/parent group. Int J Group Psychother 1982 0.75
123 Activated oncogenes in Burkitt's lymphoma. Curr Top Microbiol Immunol 1984 0.75
124 Continuing education for community health nurses. MCN Am J Matern Child Nurs 1984 0.75
125 Experimental allergic neuritis. Humoral and cellular immune responses to the cyanogen bromide peptides of the P2 protein. J Neuroimmunol 1983 0.75
126 Autotransplants in acute leukaemia. Br J Haematol 1991 0.75
127 A method for the purification of DNA/protein complexes applied to DNA topoisomerase II cleavage sites. Anal Biochem 1991 0.75
128 Budd-Chiari syndrome caused by Gaucher's disease. Pediatr Radiol 1999 0.75
129 The effectiveness of a single dose of doramectin pour-on in the control of gastrointestinal nematodes in yearling stocker cattle. Vet Parasitol 2000 0.75
130 Growth and differentiation control. Cancer Chemother Biol Response Modif 1990 0.75
131 Detection of p53 antigen expression in cytologic preparations of ovarian carcinomas. Anticancer Res 1994 0.75
132 Five hundred consecutive carotid endarterectomies: emphasis on vein patch closure. Cardiovasc Surg 1997 0.75
133 Biomedical scientist training officers' evaluation of integrated (co-terminus) Applied Biomedical Science BSc programmes: a multicentre study. Br J Biomed Sci 2011 0.75
134 Synchronisation of oestrus in ewes. Vet Rec 1967 0.75
135 Molecular epidemiology of breast cancers in northern and southern Japan: the frequency, clustering, and patterns of p53 gene mutations differ among these two low-risk populations. Oncogene 1996 0.75
136 Topotecan-filgrastim combination is an effective regimen for mobilizing peripheral blood stem cells. Bone Marrow Transplant 2001 0.75
137 Low frequency of p53 gene mutations in breast cancers of Japanese-American women. Nutr Cancer 2001 0.75
138 Combination of multiple-family therapy with parallel groups. Am J Psychother 1983 0.75
139 Stability of bombesin in serum, plasma, urine, and culture media. Clin Chem 1985 0.75
140 Growth and differentiation control. Cancer Chemother Biol Response Modif 1991 0.75
141 Management systems and productivity of hill and upland sheep. Vet Rec 1973 0.75
142 Search for chromosome instability in lymphocytes with germ-line mutations in DNA mismatch repair genes. Cancer Genet Cytogenet 1998 0.75
143 Hill farming industry. Proc Nutr Soc 1971 0.75