Published in J Virol on October 01, 2001
Functional and structural characterization of the integrase from the prototype foamy virus. Nucleic Acids Res (2008) 2.07
BET proteins promote efficient murine leukemia virus integration at transcription start sites. Proc Natl Acad Sci U S A (2013) 1.47
Structural biology of retroviral DNA integration. Virology (2011) 1.37
Cofactors for human immunodeficiency virus type 1 cDNA integration in vitro. J Virol (2003) 1.03
Molecular and genetic determinants of rous sarcoma virus integrase for concerted DNA integration. J Virol (2003) 0.96
Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature (2016) 0.89
Retroviral Integrase Structure and DNA Recombination Mechanism. Microbiol Spectr (2015) 0.83
Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution. BMC Struct Biol (2013) 0.76
Correct integration of retroviral DNA in vitro. Cell (1987) 10.73
A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev (1989) 8.80
Retroviral DNA integration: structure of an integration intermediate. Cell (1988) 8.48
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proc Natl Acad Sci U S A (1989) 8.13
The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro. Cell (1990) 7.99
The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro. Cell (1990) 7.19
Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes. Proc Natl Acad Sci U S A (1986) 6.94
Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity. Proc Natl Acad Sci U S A (1990) 6.85
The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration. J Virol (1989) 6.83
Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Mol Cell Biol (1992) 6.77
Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science (1994) 6.69
HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer. Cell (1991) 6.54
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J Virol (1992) 6.07
Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence. Cell (1989) 6.04
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science (1994) 5.47
Retroviral integrase domains: DNA binding and the recognition of LTR sequences. Nucleic Acids Res (1991) 4.39
Three-dimensional structure of the Tn5 synaptic complex transposition intermediate. Science (2000) 4.00
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc Natl Acad Sci U S A (1993) 3.99
HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro. Cell (1997) 3.98
Mutational analysis of the integrase protein of human immunodeficiency virus type 2. Proc Natl Acad Sci U S A (1992) 3.55
Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro. Virology (1992) 3.43
Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein. Nucleic Acids Res (1993) 3.42
Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration. Proc Natl Acad Sci U S A (1989) 3.28
Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding. Proc Natl Acad Sci U S A (2000) 3.26
A previously unidentified host protein protects retroviral DNA from autointegration. Proc Natl Acad Sci U S A (1998) 3.10
HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase. Proc Natl Acad Sci U S A (2000) 3.00
Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat Struct Biol (1997) 2.81
Solution structure of the DNA binding domain of HIV-1 integrase. Biochemistry (1995) 2.69
The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. J Virol (1994) 2.56
The DNA-binding domain of HIV-1 integrase has an SH3-like fold. Nat Struct Biol (1995) 2.53
Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase. J Biol Chem (1992) 2.52
Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity. Proc Natl Acad Sci U S A (1996) 2.46
Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking. EMBO J (1997) 2.42
A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo. J Virol (1992) 2.18
High-resolution structure of the catalytic domain of avian sarcoma virus integrase. J Mol Biol (1995) 2.16
Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: stimulation by the viral nucleocapsid protein. J Virol (1999) 2.13
A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proc Natl Acad Sci U S A (1994) 2.10
Concerted integration of retrovirus-like DNA by human immunodeficiency virus type 1 integrase. J Virol (1995) 1.87
Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex. Biochemistry (1998) 1.83
Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein. AIDS Res Hum Retroviruses (1992) 1.82
Concerted integration of viral DNA termini by purified avian myeloblastosis virus integrase. J Virol (1992) 1.74
Concerted integration of linear retroviral DNA by the avian sarcoma virus integrase in vitro: dependence on both long terminal repeat termini. J Virol (1996) 1.72
HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro. J Virol (1999) 1.71
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase. J Mol Biol (2000) 1.69
Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro. Biochemistry (1997) 1.69
Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking. Biochemistry (1997) 1.68
Retroviral DNA integration. Microbiol Mol Biol Rev (1999) 1.64
X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform. J Mol Biol (2000) 1.63
Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis. J Virol (1991) 1.62
Efficient concerted integration of retrovirus-like DNA in vitro by avian myeloblastosis virus integrase. Nucleic Acids Res (1994) 1.58
Characterization of the forward and reverse integration reactions of the Moloney murine leukemia virus integrase protein purified from Escherichia coli. J Biol Chem (1993) 1.44
The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc. Curr Biol (1997) 1.44
Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA. Nucleic Acids Res (1994) 1.40
High-resolution functional mapping of a cloned gene by genetic footprinting. Proc Natl Acad Sci U S A (1997) 1.25
Assembly and catalytic properties of retrovirus integrase-DNA complexes capable of efficiently performing concerted integration. J Virol (1995) 1.19
Activities and substrate specificity of the evolutionarily conserved central domain of retroviral integrase. Virology (1995) 1.18
Zinc stimulates Mg2+-dependent 3'-processing activity of human immunodeficiency virus type 1 integrase in vitro. Biochemistry (1996) 1.14
Avian retrovirus U3 and U5 DNA inverted repeats. Role Of nonsymmetrical nucleotides in promoting full-site integration by purified virion and bacterial recombinant integrases. J Biol Chem (1997) 1.10
Mapping viral DNA specificity to the central region of integrase by using functional human immunodeficiency virus type 1/visna virus chimeric proteins. J Virol (1998) 1.09
The core domain of HIV-1 integrase recognizes key features of its DNA substrates. J Biol Chem (1997) 1.05
Functional domains of Moloney murine leukemia virus integrase defined by mutation and complementation analysis. J Virol (1996) 1.01
Characterization of the human spuma retrovirus integrase by site-directed mutagenesis, by complementation analysis, and by swapping the zinc finger domain of HIV-1. J Biol Chem (1995) 1.00
Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis. J Virol (1999) 1.00
Efficiency and fidelity of full-site integration reactions using recombinant simian immunodeficiency virus integrase. J Virol (1999) 0.97
Purification of recombinant Rous sarcoma virus integrase possessing physical and catalytic properties similar to virion-derived integrase. Protein Expr Purif (1998) 0.92
Reconstitution of concerted DNA integration with purified components. Adv Virus Res (1999) 0.91
Implication of a central cysteine residue and the HHCC domain of Moloney murine leukemia virus integrase protein in functional multimerization. J Virol (1998) 0.82
Functional interactions of the HHCC domain of moloney murine leukemia virus integrase revealed by nonoverlapping complementation and zinc-dependent dimerization. J Virol (1999) 0.82
Coordinated disintegration reactions mediated by Moloney murine leukemia virus integrase. J Virol (1996) 0.82
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene (2001) 4.40
Mucosal iodine staining improves endoscopic visualization of squamous dysplasia and squamous cell carcinoma of the esophagus in Linxian, China. Cancer (1998) 2.39
Histological precursors of oesophageal squamous cell carcinoma: results from a 13 year prospective follow up study in a high risk population. Gut (2005) 2.31
Analysis of retroviral pol gene products with antisera raised against fusion proteins produced in Escherichia coli. J Virol (1986) 2.18
Mutational analysis of the envelope gene of Moloney murine leukemia virus. J Virol (1993) 2.08
Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli. J Biol Chem (1985) 2.02
Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1. J Virol (1990) 1.80
Mutational analysis of the N-linked glycosylation sites of the SU envelope protein of Moloney murine leukemia virus. J Virol (1992) 1.64
Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma. Cancer Res (2000) 1.50
Clearing of melanoma in situ with intralesional interferon alfa in a patient with xeroderma pigmentosum. Arch Dermatol (1994) 1.46
Characterization of the forward and reverse integration reactions of the Moloney murine leukemia virus integrase protein purified from Escherichia coli. J Biol Chem (1993) 1.44
Specificity of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H in removal of the minus-strand primer, tRNA(Lys3). J Biol Chem (1992) 1.44
CD97 is a processed, seven-transmembrane, heterodimeric receptor associated with inflammation. J Immunol (1996) 1.42
Analysis of bacteriophage phi X174 gene A protein-mediated termination and reinitiation of phi X DNA synthesis. II. Structural characterization of the covalent phi X A protein-DNA complex. J Biol Chem (1984) 1.41
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. Am J Pathol (1994) 1.36
Risk factors for oesophageal squamous dysplasia in adult inhabitants of a high risk region of China. Gut (2005) 1.32
High levels of carcinogenic polycyclic aromatic hydrocarbons present within food from Linxian, China may contribute to that region's high incidence of oesophageal cancer. Eur J Cancer (1998) 1.30
RNase H cleavage of tRNAPro mediated by M-MuLV and HIV-1 reverse transcriptases. Virology (1997) 1.25
Role of the His-Cys finger of Moloney murine leukemia virus integrase protein in integration and disintegration. J Virol (1993) 1.25
Studies of esophageal balloon cytology in Linxian, China. Cancer Epidemiol Biomarkers Prev (1997) 1.23
Contributions of DNA polymerase subdomains to the RNase H activity of human immunodeficiency virus type 1 reverse transcriptase. J Virol (1994) 1.21
Allelic loss in esophageal squamous cell carcinoma patients with and without family history of upper gastrointestinal tract cancer. Clin Cancer Res (1999) 1.20
Purification and characterization of an active human immunodeficiency virus type 1 RNase H domain. J Virol (1993) 1.19
Identification of novel regions of allelic loss from a genomewide scan of esophageal squamous-cell carcinoma in a high-risk Chinese population. Genes Chromosomes Cancer (2000) 1.19
Frequent inactivation of the TP53 gene in esophageal squamous cell carcinoma from a high-risk population in China. Clin Cancer Res (2001) 1.14
Development of a urinary biomarker of human exposure to deoxynivalenol. Food Chem Toxicol (2003) 1.12
Second-site changes affect viability of amphotropic/ecotropic chimeric enveloped murine leukemia viruses. J Virol (2000) 1.09
Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase. Biochemistry (1995) 1.07
Characterization of chimeras between the ecotropic Moloney murine leukemia virus and the amphotropic 4070A envelope proteins. J Virol (1996) 1.07
Analysis of cysteine mutations on the transmembrane protein of Moloney murine leukemia virus. Virology (1995) 1.03
Functional domains of Moloney murine leukemia virus integrase defined by mutation and complementation analysis. J Virol (1996) 1.01
High frequency allelic loss on chromosome 17p13.3-p11.1 in esophageal squamous cell carcinomas from a high incidence area in northern China. Carcinogenesis (2000) 1.01
RNA capping by the vaccinia virus guanylyltransferase. Structure of enzyme-guanylate intermediate. J Biol Chem (1984) 1.00
Polycyclic aromatic hydrocarbons identified in soot extracts from domestic coal-burning stoves of Henan Province, China. Environ Sci Technol (2001) 0.99
Influence of substrate structure on disintegration activity of Moloney murine leukemia virus integrase. J Virol (1993) 0.97
Expression of cyclooxygenase-2 in human squamous cell carcinoma of the esophagus; an immunohistochemical survey. Anticancer Res (1999) 0.97
RNase H requirements for the second strand transfer reaction of human immunodeficiency virus type 1 reverse transcription. J Virol (1999) 0.97
Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane protein. Virology (1997) 0.91
Functional characterization of the N termini of murine leukemia virus envelope proteins. J Virol (2001) 0.91
Detection of the von Hippel-Lindau gene deletion in cytologic specimens using microdissection and the polymerase chain reaction. Acta Cytol (1994) 0.89
von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens. Hum Pathol (1996) 0.88
Expression of cyclooxygenase-2 in human adenocarcinomas of the gastric cardia and corpus. Oncol Rep (1999) 0.87
Common genetic variants of TP53 and BRCA2 in esophageal cancer patients and healthy individuals from low and high risk areas of northern China. Cancer Detect Prev (2003) 0.87
Analysis of bacteriophage phi X174 gene A protein-mediated termination and reinitiation of phi X DNA synthesis. I. Characterization of the termination and reinitiation reactions. J Biol Chem (1984) 0.86
Implication of a central cysteine residue and the HHCC domain of Moloney murine leukemia virus integrase protein in functional multimerization. J Virol (1998) 0.82
Coordinated disintegration reactions mediated by Moloney murine leukemia virus integrase. J Virol (1996) 0.82
Substitution of Asp114 or Arg116 in the fingers domain of moloney murine leukemia virus reverse transcriptase affects interactions with the template-primer resulting in decreased processivity. J Mol Biol (2001) 0.82
Functional interactions of the HHCC domain of moloney murine leukemia virus integrase revealed by nonoverlapping complementation and zinc-dependent dimerization. J Virol (1999) 0.82
Allelic loss on chromosome bands 13q11-q13 in esophageal squamous cell carcinoma. Genes Chromosomes Cancer (2001) 0.81
Specificity of priming reaction of HIV-1 reverse transcriptase, 2'-OH or 3'-OH. J Biol Chem (1994) 0.81
Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus. Virology (1993) 0.81
Differential effects of C-terminal molecular tagged integrase on replication competent moloney murine leukemia virus. Virology (2000) 0.81
Mutational analysis of the N-terminus of Moloney murine leukemia virus integrase. Virology (2001) 0.81
Sequence requirements for removal of tRNA by an isolated human immunodeficiency virus type 1 RNase H domain. J Virol (1998) 0.81
A comparative study of the aerosolized bronchodilators, isoproterenol, metaproterenol and terbutaline in asthma. Ann Allergy (1977) 0.79
Plasma immunotherapy in a child with acquired immunodeficiency syndrome. Pediatr Infect Dis J (1993) 0.79
A low-cost, reliable, and accurate general-purpose timer. J Exp Anal Behav (1967) 0.75
Comparison of second-strand transfer requirements and RNase H cleavages catalyzed by human immunodeficiency virus type 1 reverse transcriptase (RT) and E478Q RT. J Virol (2000) 0.75
A common sense approach to investing for income. CDS Rev (1992) 0.75
Assays for retroviral RNase H. Methods Enzymol (2001) 0.75
Changes to the quantity and processing of starchy foods in a western diet can increase polysaccharides escaping digestion and improve in vitro fermentation variables. Br J Nutr (2000) 0.75
Quality assurance. J Psychosoc Nurs Ment Health Serv (1988) 0.75