D P Bartel

Author PubWeight™ 121.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001 44.16
2 RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 2000 20.32
3 Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 1999 8.21
4 Synthesizing life. Nature 2001 6.55
5 RNA-catalyzed RNA polymerization: accurate and general RNA-templated primer extension. Science 2001 4.53
6 The guanosine binding site of the Tetrahymena ribozyme. Nature 1989 4.43
7 Phylogenetic analysis of tmRNA secondary structure. RNA 1996 2.95
8 RNA-catalysed nucleotide synthesis. Nature 1998 2.80
9 Structurally complex and highly active RNA ligases derived from random RNA sequences. Science 1995 2.53
10 One sequence, two ribozymes: implications for the emergence of new ribozyme folds. Science 2000 2.53
11 Resuming translation on tmRNA: a unique mode of determining a reading frame. EMBO J 1999 2.14
12 RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature 1996 1.84
13 PCR product with strands of unequal length. Nucleic Acids Res 1995 1.65
14 The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence. Biochemistry 1999 1.63
15 Accessing rare activities from random RNA sequences: the importance of the length of molecules in the starting pool. Chem Biol 1997 1.58
16 Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template. Nucleic Acids Res 1995 1.57
17 The secondary structure and sequence optimization of an RNA ligase ribozyme. Nucleic Acids Res 1995 1.45
18 The hammerhead cleavage reaction in monovalent cations. RNA 2001 1.44
19 Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. EMBO J 1998 1.43
20 Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation. J Am Chem Soc 1996 1.41
21 Bioactive and nuclease-resistant L-DNA ligand of vasopressin. Proc Natl Acad Sci U S A 1997 1.40
22 The tmRNA Website. Nucleic Acids Res 1998 1.37
23 Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds. J Am Chem Soc 1996 1.30
24 Kinetic framework for ligation by an efficient RNA ligase ribozyme. Biochemistry 2000 1.23
25 1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry 1994 1.18
26 A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. RNA 2001 0.98
27 Selection and design of high-affinity RNA ligands for HIV-1 Rev. Gene 1993 0.95
28 Recognition of nucleoside triphosphates during RNA-catalyzed primer extension. Biochemistry 2000 0.89
29 RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature 1996 0.75