Elliot J Androphy

Author PubWeight™ 43.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron. Mol Cell Biol 2006 2.41
2 Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes. Nucleic Acids Res 2006 1.84
3 A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy. J Cell Biol 2003 1.75
4 In vivo selection reveals combinatorial controls that define a critical exon in the spinal muscular atrophy genes. RNA 2004 1.60
5 An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy. Biochem Biophys Res Commun 2004 1.56
6 SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet 2002 1.53
7 Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism. Chem Biol 2004 1.45
8 The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells. J Cell Sci 2006 1.42
9 ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance. Mol Cell 2006 1.39
10 The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3. Cell Cycle 2012 1.24
11 A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy. J Biol Chem 2001 1.20
12 Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes. J Virol 2002 1.19
13 Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras. J Virol 2004 1.10
14 The regulation and regulatory activities of alternative splicing of the SMN gene. Crit Rev Eukaryot Gene Expr 2004 1.08
15 The COPI vesicle complex binds and moves with survival motor neuron within axons. Hum Mol Genet 2011 1.08
16 Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins. Antiviral Res 2006 1.02
17 Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function. Mol Cell Biol 2010 1.00
18 COPI transport complexes bind to specific RNAs in neuronal cells. Hum Mol Genet 2012 0.99
19 Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability. J Virol 2008 0.97
20 Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. J Invest Dermatol 2013 0.97
21 Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT. J Virol 2007 0.96
22 Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation. J Virol 2006 0.93
23 The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein. Brain Res Mol Brain Res 2003 0.92
24 PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy. Cell Cycle 2012 0.91
25 Discovery, synthesis, and biological evaluation of novel SMN protein modulators. J Med Chem 2011 0.91
26 Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway. Mol Cell Biol 2004 0.90
27 hAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cells. J Virol 2008 0.89
28 Mitotic kinesin-like protein 2 binds and colocalizes with papillomavirus E2 during mitosis. J Virol 2006 0.89
29 Determinants of stability for the E6 protein of papillomavirus type 16. J Mol Biol 2009 0.89
30 Transcriptional repression of E-cadherin by human papillomavirus type 16 E6. PLoS One 2012 0.88
31 Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy. Hum Mol Genet 2013 0.88
32 Identification of novel compounds that increase SMN protein levels using an improved SMN2 reporter cell assay. J Biomol Screen 2012 0.86
33 Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells. J Proteome Res 2010 0.86
34 Acetylation of conserved lysines in bovine papillomavirus E2 by p300. J Virol 2012 0.85
35 Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds. EMBO Mol Med 2013 0.84
36 Topography of bovine papillomavirus E2 protein on the viral genome during the cell cycle. Virology 2009 0.83
37 Therapeutic strategies for the treatment of spinal muscular atrophy. Future Med Chem 2012 0.81
38 Bovine papillomavirus type 1 E6-induced sensitization to apoptosis is distinct from its transforming activity. Virology 2002 0.80
39 Differential regulation of the SMN2 gene by individual HDAC proteins. Biochem Biophys Res Commun 2011 0.79
40 Opposing effects of bovine papillomavirus type 1 E6 and E7 genes on Fas-mediated apoptosis. Oncogene 2005 0.75