Published in Mol Cell on December 28, 2006
Welcome the family of FANCJ-like helicases to the block of genome stability maintenance proteins. Cell Mol Life Sci (2009) 1.54
Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1. Am J Hum Genet (2010) 1.42
Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4. F1000 Biol Rep (2009) 1.36
Chromatin adaptor Brd4 modulates E2 transcription activity and protein stability. J Biol Chem (2008) 1.36
The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. J Virol (2008) 1.35
The papillomavirus E2 proteins. Virology (2013) 1.30
Replication and partitioning of papillomavirus genomes. Adv Virus Res (2008) 1.21
Biochemical characterization of Warsaw breakage syndrome helicase. J Biol Chem (2011) 1.19
Human papillomavirus molecular biology and disease association. Rev Med Virol (2015) 1.09
Chromatin organization and virus gene expression. J Cell Physiol (2008) 1.08
Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia. Viruses (2015) 1.06
Brd4 regulation of papillomavirus protein E2 stability. J Virol (2009) 1.02
HPV-16 E2 contributes to induction of HPV-16 late gene expression by inhibiting early polyadenylation. EMBO J (2012) 1.00
Emerging critical roles of Fe-S clusters in DNA replication and repair. Biochim Biophys Acta (2015) 0.96
Papillomavirus interaction with cellular chromatin. Biochim Biophys Acta (2009) 0.96
Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome. Cell Mol Life Sci (2014) 0.95
Mitotic chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human EBNA1-binding protein 2 (EBP2). J Cell Sci (2009) 0.94
Hitchhiking on host chromatin: how papillomaviruses persist. Biochim Biophys Acta (2012) 0.93
Inhibition of transcription and DNA replication by the papillomavirus E8-E2C protein is mediated by interaction with corepressor molecules. J Virol (2008) 0.93
Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression. Am J Cancer Res (2011) 0.91
An interaction between human papillomavirus 16 E2 and TopBP1 is required for optimum viral DNA replication and episomal genome establishment. J Virol (2012) 0.91
Mitotic kinesin-like protein 2 binds and colocalizes with papillomavirus E2 during mitosis. J Virol (2006) 0.89
Current understanding of the role of the Brd4 protein in the papillomavirus lifecycle. Viruses (2013) 0.89
Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators. PLoS Pathog (2015) 0.87
Analysis of cis-elements that facilitate extrachromosomal persistence of human papillomavirus genomes. Virology (2008) 0.86
Targeting mitotic chromosomes: a conserved mechanism to ensure viral genome persistence. Proc Biol Sci (2009) 0.86
The HPV E2-Host Protein-Protein Interactions: A Complex Hijacking of the Cellular Network. Open Virol J (2012) 0.86
The Epstein-Barr Virus EBNA1 Protein. Scientifica (Cairo) (2012) 0.85
Acetylation of conserved lysines in bovine papillomavirus E2 by p300. J Virol (2012) 0.85
Mammalian ChlR1 has a role in heterochromatin organization. Exp Cell Res (2011) 0.84
Topography of bovine papillomavirus E2 protein on the viral genome during the cell cycle. Virology (2009) 0.83
The human papillomavirus type 16 L1 protein directly interacts with E2 and enhances E2-dependent replication and transcription activation. J Gen Virol (2015) 0.81
Interaction of the papillomavirus E8--E2C protein with the cellular CHD6 protein contributes to transcriptional repression. J Virol (2010) 0.81
Phosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomes. PLoS One (2014) 0.79
Human papillomavirus infections: warts or cancer? Cold Spring Harb Perspect Biol (2013) 0.78
Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency. PLoS One (2015) 0.76
The cellular DNA helicase ChlR1 regulates chromatin and nuclear matrix attachment of the human papillomavirus type 16 E2 protein and high copy viral genome establishment. J Virol (2016) 0.75
Order from clutter: selective interactions at mammalian replication origins. Nat Rev Genet (2016) 0.75
Failure to interact with Brd4 alters the ability of HPV16 E2 to regulate host genome expression and cellular movement. Virus Res (2015) 0.75
The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2. PLoS Pathog (2016) 0.75
Association of human papillomavirus type 16 E2 with Rad50-interacting protein 1 enhances viral DNA replication. J Virol (2016) 0.75
Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron. Mol Cell Biol (2006) 2.41
Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes. Nucleic Acids Res (2006) 1.84
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy. J Cell Biol (2003) 1.75
In vivo selection reveals combinatorial controls that define a critical exon in the spinal muscular atrophy genes. RNA (2004) 1.60
An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy. Biochem Biophys Res Commun (2004) 1.56
SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet (2002) 1.53
Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism. Chem Biol (2004) 1.45
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells. J Cell Sci (2006) 1.42
The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3. Cell Cycle (2012) 1.24
A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy. J Biol Chem (2001) 1.20
Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes. J Virol (2002) 1.19
Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras. J Virol (2004) 1.10
The COPI vesicle complex binds and moves with survival motor neuron within axons. Hum Mol Genet (2011) 1.08
The regulation and regulatory activities of alternative splicing of the SMN gene. Crit Rev Eukaryot Gene Expr (2004) 1.08
Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins. Antiviral Res (2006) 1.02
Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function. Mol Cell Biol (2010) 1.00
COPI transport complexes bind to specific RNAs in neuronal cells. Hum Mol Genet (2012) 0.99
Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability. J Virol (2008) 0.97
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. J Invest Dermatol (2013) 0.97
Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT. J Virol (2007) 0.96
Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation. J Virol (2006) 0.93
The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein. Brain Res Mol Brain Res (2003) 0.92
PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy. Cell Cycle (2012) 0.91
Discovery, synthesis, and biological evaluation of novel SMN protein modulators. J Med Chem (2011) 0.91
Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway. Mol Cell Biol (2004) 0.90
hAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cells. J Virol (2008) 0.89
Determinants of stability for the E6 protein of papillomavirus type 16. J Mol Biol (2009) 0.89
Mitotic kinesin-like protein 2 binds and colocalizes with papillomavirus E2 during mitosis. J Virol (2006) 0.89
Transcriptional repression of E-cadherin by human papillomavirus type 16 E6. PLoS One (2012) 0.88
Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy. Hum Mol Genet (2013) 0.88
Identification of novel compounds that increase SMN protein levels using an improved SMN2 reporter cell assay. J Biomol Screen (2012) 0.86
Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells. J Proteome Res (2010) 0.86
Acetylation of conserved lysines in bovine papillomavirus E2 by p300. J Virol (2012) 0.85
Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds. EMBO Mol Med (2013) 0.84
Topography of bovine papillomavirus E2 protein on the viral genome during the cell cycle. Virology (2009) 0.83
Therapeutic strategies for the treatment of spinal muscular atrophy. Future Med Chem (2012) 0.81
Bovine papillomavirus type 1 E6-induced sensitization to apoptosis is distinct from its transforming activity. Virology (2002) 0.80
Differential regulation of the SMN2 gene by individual HDAC proteins. Biochem Biophys Res Commun (2011) 0.79
Opposing effects of bovine papillomavirus type 1 E6 and E7 genes on Fas-mediated apoptosis. Oncogene (2005) 0.75