E2F-1 up-regulates c-Myc and p14(ARF) and induces apoptosis in colon cancer cells.

PubWeight™: 1.10‹?› | Rank: Top 10%

🔗 View Article (PMID 11705881)

Published in Clin Cancer Res on November 01, 2001

Authors

M J Elliott1, Y B Dong, H Yang, K M McMasters

Author Affiliations

1: Department of Surgery, James Graham Brown Cancer Center, University of Louisville, 529 South Jackson Street, Louisville, KY 40202, USA.

Articles citing this

E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer. Gastroenterology (2008) 1.29

Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells. Mol Cancer Ther (2010) 1.09

Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. Hepatology (2013) 0.99

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1. Cancer Res (2010) 0.94

Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1. Nucleic Acids Res (2006) 0.93

Adenovirus-mediated expression of truncated E2F-1 suppresses tumor growth in vitro and in vivo. Cancer (2010) 0.88

The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence. J Biol Chem (2012) 0.87

Epigenetic changes in the CDKN2A locus are associated with differential expression of P16INK4A and P14ARF in HPV-positive oropharyngeal squamous cell carcinoma. Cancer Med (2015) 0.86

A transcriptionally active pRb-E2F1-P/CAF signaling pathway is central to TGFβ-mediated apoptosis. Cell Death Dis (2012) 0.85

Transcription addiction: can we garner the Yin and Yang functions of E2F1 for cancer therapy? Cell Death Dis (2014) 0.84

Developing adenoviral vectors encoding therapeutic genes toxic to host cells: comparing binary and single-inducible vectors expressing truncated E2F-1. Virology (2009) 0.82

Adeno-associated virus type 2 infection of nude mouse human breast cancer xenograft induces necrotic death and inhibits tumor growth. Cancer Biol Ther (2014) 0.80

Adeno-associated virus type 2 infection activates caspase dependent and independent apoptosis in multiple breast cancer lines but not in normal mammary epithelial cells. Mol Cancer (2011) 0.80

Arf induction by Tgfβ is influenced by Sp1 and C/ebpβ in opposing directions. PLoS One (2013) 0.79

Enhanced cancer cell killing by truncated E2F-1 used in combination with oncolytic adenovirus. Virology (2012) 0.79

Glycogen Synthase Kinase 3β Inhibitor (2'Z,3'E)-6-Bromo-indirubin- 3'-Oxime Enhances Drug Resistance to 5-Fluorouracil Chemotherapy in Colon Cancer Cells. Chin J Cancer Res (2012) 0.78

E2F1/TS Immunophenotype and Survival of Patients with Colorectal Cancer Treated with 5FU-Based Adjuvant Therapy. Pathol Oncol Res (2016) 0.75

Sulforaphane Inhibits c-Myc-Mediated Prostate Cancer Stem-Like Traits. J Cell Biochem (2016) 0.75

Expression level is a key determinant of E2F1-mediated cell fate. Cell Death Differ (2017) 0.75

A Proteomics Analysis Reveals 9 Up-Regulated Proteins Associated with Altered Cell Signaling in Colon Cancer Patients. Protein J (2017) 0.75

Articles by these authors

(truncated to the top 100)

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science (2001) 22.06

HMG-1 as a late mediator of endotoxin lethality in mice. Science (1999) 17.72

Health information on the Internet: accessibility, quality, and readability in English and Spanish. JAMA (2001) 15.23

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature (2000) 11.49

Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol (2001) 10.20

Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol (2001) 9.68

High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med (2000) 7.38

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell (1999) 6.59

Regulation of flowering time by Arabidopsis photoreceptors. Science (1998) 5.11

VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J Cell Biol (1995) 5.04

Neuraxial block, death and serious cardiovascular morbidity in the POISE trial. Br J Anaesth (2013) 4.60

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain. Blood (2001) 3.93

The contribution of mild and moderate preterm birth to infant mortality. Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System. JAMA (2000) 3.91

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Cell (1998) 3.86

Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence. Proc Natl Acad Sci U S A (1999) 3.79

Rhabdomyolysis. Intern Emerg Med (2007) 3.56

Diagnostic strategies in CADASIL. Neurology (2002) 3.52

Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome 2. Proc Natl Acad Sci U S A (1998) 3.34

Perinuclear antineutrophil cytoplasmic antibodies in patients with Crohn's disease define a clinical subgroup. Gastroenterology (1996) 3.08

A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci U S A (1996) 3.07

Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue. J Biol Chem (1993) 3.02

Extracellular role of HMGB1 in inflammation and sepsis. J Intern Med (2004) 2.94

Does oxidative damage to DNA increase with age? Proc Natl Acad Sci U S A (2001) 2.91

Fungi isolated from tobacco leaves and brown-spot lesions before and after flue-curing. Appl Microbiol (1968) 2.87

HMGB1 as a late mediator of lethal systemic inflammation. Am J Respir Crit Care Med (2001) 2.80

von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF. Hum Mol Genet (2001) 2.79

Antagonistic actions of Arabidopsis cryptochromes and phytochrome B in the regulation of floral induction. Development (1999) 2.76

Familial expression of anti-Saccharomyces cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease. Gut (2000) 2.71

Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem (2001) 2.57

Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. Circulation (2000) 2.56

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1. Proc Natl Acad Sci U S A (1997) 2.55

Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics. Gut (2000) 2.47

High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. Arthritis Rheum (2002) 2.45

Randomized phase III study 306: adjunctive perampanel for refractory partial-onset seizures. Neurology (2012) 2.45

The product of the pleiotropic Escherichia coli gene csrA modulates glycogen biosynthesis via effects on mRNA stability. J Bacteriol (1995) 2.40

Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology (2000) 2.37

Establishing human prostate cancer cell xenografts in bone: induction of osteoblastic reaction by prostate-specific antigen-producing tumors in athymic and SCID/bg mice using LNCaP and lineage-derived metastatic sublines. Int J Cancer (1998) 2.36

Superior ex vivo cord blood expansion following co-culture with bone marrow-derived mesenchymal stem cells. Bone Marrow Transplant (2006) 2.29

Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell (2001) 2.29

Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity. Arthritis Rheum (2003) 2.26

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma. J Hepatol (2000) 2.22

Lamivudine in late pregnancy to prevent perinatal transmission of hepatitis B virus infection: a multicentre, randomized, double-blind, placebo-controlled study. J Viral Hepat (2008) 2.19

Improved staging of node-negative patients with intermediate to thick melanomas (>1 mm) with the use of lymphatic mapping and sentinel lymph node biopsy. Ann Surg Oncol (2001) 2.19

CD8(+) T-cell selection, function, and death in the primary immune response in vivo. J Clin Invest (2000) 2.19

An open-label pilot study of low-dose thalidomide in chronically active, steroid-dependent Crohn's disease. Gastroenterology (1999) 2.16

Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC). J Virol (2001) 2.14

Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro. Hepatology (1998) 2.12

Inhibition of nuclear hormone receptor activity by calreticulin. Nature (1994) 2.11

Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display. Biochemistry (1999) 2.10

Pleiotropic regulation of central carbohydrate metabolism in Escherichia coli via the gene csrA. J Biol Chem (1995) 2.10

Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation. Auton Neurosci (2000) 2.06

Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor. Cancer Res (2000) 2.02

High mobility group 1 B-box mediates activation of human endothelium. J Intern Med (2003) 2.00

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome. J Cell Biol (1999) 1.93

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. Mol Cell Biol (2001) 1.91

Electrical properties and conduction in reperfused papillary muscle. Circ Res (2001) 1.91

Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion. J Biol Chem (1999) 1.86

Induction of alloreactive cytotoxic T cells by acute virus infection of mice. J Immunol (1986) 1.84

Molecular mechanisms of BK channel activation. Cell Mol Life Sci (2009) 1.81

Epstein-barr virus regulates c-MYC, apoptosis, and tumorigenicity in Burkitt lymphoma. Mol Cell Biol (1999) 1.80

Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands. Cell Death Differ (2008) 1.80

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida. Mol Genet Metab (1999) 1.75

Communicating about risk of infectious diseases. JAMA (1996) 1.74

Production of immunoglobulin G and G1 antibodies to cytoskeletal protein by lamina propria cells in ulcerative colitis. Gastroenterology (1995) 1.74

A genome-wide search identifies potential new susceptibility loci for Crohn's disease. Inflamm Bowel Dis (1999) 1.74

Mutations affecting the development of the embryonic zebrafish brain. Development (1996) 1.73

Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. Am J Physiol Heart Circ Physiol (2001) 1.71

Vitronectin stabilizes thrombi and vessel occlusion but plays a dual role in platelet aggregation. J Thromb Haemost (2005) 1.70

Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity. Gastroenterology (1992) 1.67

Genetic dissection of ethanol tolerance in the budding yeast Saccharomyces cerevisiae. Genetics (2006) 1.67

Molecular genetic analysis of Rts1p, a B' regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A. Mol Cell Biol (1997) 1.66

The A alpha mating locus of Schizophyllum commune encodes two dissimilar multiallelic homeodomain proteins. Proc Natl Acad Sci U S A (1992) 1.66

Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein. J Bacteriol (1999) 1.62

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia. Leukemia (2008) 1.61

Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60

Accuracy of sentinel lymph node biopsy for patients with T2 and T3 breast cancers. Am Surg (2001) 1.59

ACE-Asia intercomparison of a thermal-optical method for the determination of particle-phase organic and elemental carbon. Environ Sci Technol (2003) 1.59

Vascularization of the human fetal retina: roles of vasculogenesis and angiogenesis. Invest Ophthalmol Vis Sci (2000) 1.58

Bootstrap confidence intervals for the sensitivity of a quantitative diagnostic test. Stat Med (2000) 1.57

The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities. J Biol Chem (1994) 1.56

Determinants of unexplained antepartum fetal deaths. Obstet Gynecol (2000) 1.54

Genetic epidemiological study of keratoconus: evidence for major gene determination. Am J Med Genet (2000) 1.52

A new American Joint Committee on Cancer staging system for cutaneous melanoma. Cancer (2000) 1.52

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases. Genes Immun (2007) 1.50

Sentinel lymph node biopsy for breast cancer: impact of the number of sentinel nodes removed on the false-negative rate. J Am Coll Surg (2001) 1.49

Granulocytic Ehrlichiae in Ixodes persulcatus ticks from an area in China where Lyme disease is endemic. J Clin Microbiol (2000) 1.49

Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver. Am J Physiol Gastrointest Liver Physiol (2000) 1.48

Secular trends in preterm birth: a hospital-based cohort study. JAMA (1998) 1.48

Pacifier use, early weaning, and cry/fuss behavior: a randomized controlled trial. JAMA (2001) 1.48

The taste of monosodium glutamate: membrane receptors in taste buds. J Neurosci (1996) 1.47

Care arrangements, grief and psychological problems among children orphaned by AIDS in China. AIDS Care (2007) 1.47

Critical pediatric equipment availability in Canadian hospital emergency departments. Ann Emerg Med (2001) 1.46

Identification of Ehrlichia chaffeensis by nested PCR in ticks from Southern China. J Clin Microbiol (2000) 1.44

4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer. J Biol Chem (1999) 1.44

Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density. Gut (2004) 1.43

Quantitative characterization of changes in dynamical behavior for single-particle tracking studies. J Phys Chem B (2006) 1.42

Tissue manganese concentrations and antioxidant enzyme activities in rats given total parenteral nutrition with and without supplemental manganese. JPEN J Parenter Enteral Nutr (1996) 1.42

First experience with direct, selective factor Xa inhibition in patients with non-ST-elevation acute coronary syndromes: results of the XaNADU-ACS Trial. J Thromb Haemost (2005) 1.42

Association of hypertension with T594M mutation in beta subunit of epithelial sodium channels in black people resident in London. Lancet (1998) 1.42