Published in J Biol Chem on November 21, 2001
The NR4A subgroup: immediate early response genes with pleiotropic physiological roles. Nucl Recept Signal (2006) 2.35
MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling. Biochem J (2005) 1.42
Molecular mechanism of suppression of testicular steroidogenesis by proinflammatory cytokine tumor necrosis factor alpha. Mol Cell Biol (2004) 1.19
Molecular characterization of bovine placental and ovarian 20α-hydroxysteroid dehydrogenase. Reproduction (2011) 0.97
Mechanisms of protein kinase C signaling in the modulation of 3',5'-cyclic adenosine monophosphate-mediated steroidogenesis in mouse gonadal cells. Endocrinology (2009) 0.93
Effector ExoU from the type III secretion system is an important modulator of gene expression in lung epithelial cells in response to Pseudomonas aeruginosa infection. Infect Immun (2003) 0.92
Prostaglandin F2alpha stimulates the expression and secretion of transforming growth factor B1 via induction of the early growth response 1 gene (EGR1) in the bovine corpus luteum. Mol Endocrinol (2007) 0.92
ATF3 expression in the corpus luteum: possible role in luteal regression. Mol Endocrinol (2013) 0.88
Prostaglandin F2alpha represses IGF-I-stimulated IRS1/phosphatidylinositol-3-kinase/AKT signaling in the corpus luteum: role of ERK and P70 ribosomal S6 kinase. Mol Endocrinol (2010) 0.84
PGF2alpha induced differential expression of genes involved in turnover of extracellular matrix in rat decidual cells. Reprod Biol Endocrinol (2005) 0.84
The role of heterodimeric AP-1 protein comprised of JunD and c-Fos proteins in hematopoiesis. J Biol Chem (2012) 0.82
Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77. Arterioscler Thromb Vasc Biol (2012) 0.81
Activation of Gq/11 in the mouse corpus luteum is required for parturition. Mol Endocrinol (2014) 0.79
Regulation of Nur77 gene expression by prostanoids in cementoblastic cells. Arch Oral Biol (2009) 0.78
Transforming growth factor-β1 signaling represses testicular steroidogenesis through cross-talk with orphan nuclear receptor Nur77. PLoS One (2014) 0.78
ERK signaling, but not c-Raf, is required for gonadotropin-releasing hormone (GnRH)-induced regulation of Nur77 in pituitary gonadotropes. Endocrinology (2011) 0.76
NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice. PLoS One (2012) 0.76
Tacrolimus and sirolimus induce reproductive abnormalities in female rats. Transplantation (2011) 0.76
Parturition failure in mice lacking Mamld1. Sci Rep (2015) 0.75
The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells. BMC Biotechnol (2014) 0.75
Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells. J Immunol (2016) 0.75
Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation. Biol Reprod (2016) 0.75
Functions and mechanisms of action of CCN matricellular proteins. Int J Biochem Cell Biol (2008) 3.62
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol (2010) 3.29
Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat Rev Drug Discov (2011) 3.26
CYR61 (CCN1) is essential for placental development and vascular integrity. Mol Cell Biol (2002) 2.94
The molecular control of corpus luteum formation, function, and regression. Endocr Rev (2006) 2.15
FoxM1, a critical regulator of oxidative stress during oncogenesis. EMBO J (2009) 2.11
Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells. J Biol Chem (2002) 2.00
CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family. J Biol Chem (2003) 1.70
Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. EMBO J (2007) 1.65
FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness. J Biol Chem (2008) 1.58
Identification of a novel integrin alphavbeta3 binding site in CCN1 (CYR61) critical for pro-angiogenic activities in vascular endothelial cells. J Biol Chem (2004) 1.52
Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Mol Cell Biol (2013) 1.47
Functional inactivation of the mouse nucleolar protein Bop1 inhibits multiple steps in pre-rRNA processing and blocks cell cycle progression. J Biol Chem (2002) 1.45
The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans. Endocrinology (2002) 1.45
Deregulation of FoxM1b leads to tumour metastasis. EMBO Mol Med (2010) 1.43
Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis. Mol Cell (2004) 1.42
Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase. Mol Cell Biol (2008) 1.42
Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages. J Immunol (2010) 1.42
The matricellular protein CCN1 is essential for cardiac development. Circ Res (2006) 1.41
Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61). J Biol Chem (2003) 1.38
Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing. J Biol Chem (2004) 1.37
Cellular senescence controls fibrosis in wound healing. Aging (Albany NY) (2010) 1.36
Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis. Mol Cancer Res (2009) 1.30
Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase. J Biol Chem (2009) 1.28
Assays for ribosomal RNA processing and ribosome assembly. Curr Protoc Cell Biol (2008) 1.27
The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. J Cell Biol (2005) 1.26
FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression. J Biol Chem (2007) 1.25
Prolactin regulation of estrogen receptor expression. Trends Endocrinol Metab (2003) 1.19
A conserved phosphorylation site within the forkhead domain of FoxM1B is required for its activation by cyclin-CDK1. J Biol Chem (2009) 1.17
Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions. J Biol Chem (2004) 1.13
Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Mol Cell Biol (2009) 1.13
Decidual prolactin silences the expression of genes detrimental to pregnancy. Endocrinology (2007) 1.11
Silencing of RNA helicase II/Gualpha inhibits mammalian ribosomal RNA production. J Biol Chem (2003) 1.07
Identification of a novel integrin alphaMbeta2 binding site in CCN1 (CYR61), a matricellular protein expressed in healing wounds and atherosclerotic lesions. J Biol Chem (2003) 1.06
Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells. Am J Respir Cell Mol Biol (2005) 1.01
CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB. J Clin Invest (2015) 1.00
Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4. Endocrinology (2002) 1.00
Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol (2013) 0.99
Prolactin signaling through the short form of its receptor represses forkhead transcription factor FOXO3 and its target gene galt causing a severe ovarian defect. Mol Endocrinol (2007) 0.96
The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells. J Biol Chem (2003) 0.96
Progesterone promotes survival of the rat corpus luteum in the absence of cognate receptors. Biol Reprod (2003) 0.94
The heparin-binding site of antithrombin is crucial for antiangiogenic activity. Blood (2005) 0.94
Expression of angiogenic factor Cyr61 during neuronal cell death via the activation of c-Jun N-terminal kinase and serum response factor. J Biol Chem (2003) 0.94
Intact follicular maturation and defective luteal function in mice deficient for cyclin- dependent kinase-4. Endocrinology (2002) 0.93
Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines. J Cell Commun Signal (2009) 0.93
Restricting conformational flexibility of the switch II region creates a dominant-inhibitory phenotype in Obg GTPase Nog1. Mol Cell Biol (2007) 0.91
TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release. PLoS One (2012) 0.90
Prolactin receptor-associated protein/17beta-hydroxysteroid dehydrogenase type 7 gene (Hsd17b7) plays a crucial role in embryonic development and fetal survival. Mol Endocrinol (2008) 0.90
The role of interleukin-11 in pregnancy involves up-regulation of alpha2-macroglobulin gene through janus kinase 2-signal transducer and activator of transcription 3 pathway in the decidua. Mol Endocrinol (2006) 0.90
Androstenedione interferes in luteal regression by inhibiting apoptosis and stimulating progesterone production. Biol Reprod (2002) 0.89
Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin. Cancer Biol Ther (2010) 0.88
Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells. Blood (2003) 0.88
Generation of mice expressing only the long form of the prolactin receptor reveals that both isoforms of the receptor are required for normal ovarian function. Biol Reprod (2012) 0.87
Involvement of cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in interleukin 11 stimulation of decidualization in mice. Biol Reprod (2007) 0.87
Prolactin signaling mechanisms in ovary. Mol Cell Endocrinol (2011) 0.86
Degradome products of the matricellular protein CCN1 as modulators of pathological angiogenesis in the retina. J Biol Chem (2013) 0.85
Prolactin independent rescue of mouse corpus luteum life span: identification of prolactin and luteinizing hormone target genes. Am J Physiol Endocrinol Metab (2009) 0.84
The involvement of apoptotic regulators during in vitro decidualization. Eur J Endocrinol (2003) 0.84
PGF2alpha induced differential expression of genes involved in turnover of extracellular matrix in rat decidual cells. Reprod Biol Endocrinol (2005) 0.84
Inhibition of MAPK by prolactin signaling through the short form of its receptor in the ovary and decidua: involvement of a novel phosphatase. J Biol Chem (2011) 0.84
Decidual activin: its role in the apoptotic process and its regulation by prolactin. Biol Reprod (2002) 0.83
In vivo hormonal environment leads to differential susceptibility of the corpus luteum to apoptosis in vitro. Biol Reprod (2003) 0.83
Regulation of transcription factors and repression of Sp1 by prolactin signaling through the short isoform of its cognate receptor. Endocrinology (2009) 0.82
Prostaglandin F(2alpha) (PGF(2alpha)) and prolactin signaling: PGF(2alpha)-mediated inhibition of prolactin receptor expression in the Corpus luteum. Endocrinology (2003) 0.82
The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells. Mol Endocrinol (2011) 0.81
Cloning and characterization of a 5' regulatory region of the prolactin receptor-associated protein/17{beta} hydroxysteroid dehydrogenase 7 gene. Endocrinology (2005) 0.81
CCN3 and bone marrow cells. J Cell Commun Signal (2009) 0.80
Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues. Reprod Biol Endocrinol (2009) 0.78
Estrogen-induced CCN1 is critical for establishment of endometriosis-like lesions in mice. Mol Endocrinol (2014) 0.78
The extracellular matrix protein CCN1 dictates TNFα and FasL cytotoxicity in vivo. Adv Exp Med Biol (2011) 0.77
Robert H. Costa: 1957-2006. Hepatology (2006) 0.76
Rat decidual cell cultures. Methods Mol Med (2006) 0.75