Published in J Cell Sci on December 01, 2001
Integrin signalling at a glance. J Cell Sci (2009) 3.28
Tetraspanins: push and pull in suppressing and promoting metastasis. Nat Rev Cancer (2008) 3.04
Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1. J Cell Biol (2006) 2.38
Regulation of B1 cell migration by signals through Toll-like receptors. J Exp Med (2006) 2.11
CD81 is a central regulator of cellular events required for hepatitis C virus infection of human hepatocytes. J Virol (2008) 2.09
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli. PLoS Pathog (2007) 2.01
Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. EMBO J (2006) 1.93
Palmitoylation supports assembly and function of integrin-tetraspanin complexes. J Cell Biol (2004) 1.89
Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol (2008) 1.75
Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression. Breast Cancer Res (2004) 1.71
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases. J Cell Biol (2004) 1.69
PKC epsilon controls the traffic of beta1 integrins in motile cells. EMBO J (2002) 1.67
Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells. Cell (2016) 1.66
Cytoskeleton-plasma membrane-cell wall continuum in plants. Emerging links revisited. Plant Physiol (2003) 1.65
CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization. Cancer Res (2008) 1.64
Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening. Proc Natl Acad Sci U S A (2003) 1.63
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
An extracellular site on tetraspanin CD151 determines alpha 3 and alpha 6 integrin-dependent cellular morphology. J Cell Biol (2002) 1.61
Characterization of mice lacking the tetraspanin superfamily member CD151. Mol Cell Biol (2004) 1.57
Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation. Mol Cancer (2013) 1.56
Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro. Blood (2006) 1.53
EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells. Biochem J (2003) 1.50
alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion. J Cell Biol (2003) 1.49
A critical role for tetraspanin CD151 in alpha3beta1 and alpha6beta4 integrin-dependent tumor cell functions on laminin-5. Mol Biol Cell (2006) 1.47
Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association. Mol Biol Cell (2004) 1.36
Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking. Biochem J (2004) 1.36
Different domains of CD81 mediate distinct stages of hepatitis C virus pseudoparticle entry. J Virol (2006) 1.35
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. J Clin Invest (2008) 1.35
Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-A resolution. J Cell Biol (2006) 1.34
Unraveling the pathophysiology of Sjogren syndrome-associated dry eye disease. Ocul Surf (2009) 1.33
Syntenin-1 is a new component of tetraspanin-enriched microdomains: mechanisms and consequences of the interaction of syntenin-1 with CD63. Mol Cell Biol (2006) 1.32
Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets. Expert Rev Mol Med (2010) 1.30
Lamprey lymphocyte-like cells express homologs of genes involved in immunologically relevant activities of mammalian lymphocytes. Proc Natl Acad Sci U S A (2002) 1.28
Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors. Hear Res (2009) 1.26
Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis. J Cell Sci (2007) 1.24
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. Am J Hum Genet (2015) 1.23
Wound healing is defective in mice lacking tetraspanin CD151. J Invest Dermatol (2006) 1.22
EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5. J Cell Biol (2003) 1.22
Human homologues of a Borrelia T cell epitope associated with antibiotic-refractory Lyme arthritis. Mol Immunol (2007) 1.20
Structural organization and interactions of transmembrane domains in tetraspanin proteins. BMC Struct Biol (2005) 1.19
Extracellular engagement of alpha6 integrin inhibited urokinase-type plasminogen activator-mediated cleavage and delayed human prostate bone metastasis. Cancer Res (2009) 1.18
Sjögren's syndrome: an old tale with a new twist. Arch Immunol Ther Exp (Warsz) (2009) 1.16
Tetraspanins in viral infections: a fundamental role in viral biology? J Virol (2005) 1.16
Induction of neuro-protective/regenerative genes in stem cells infiltrating post-ischemic brain tissue. Exp Transl Stroke Med (2010) 1.13
The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins. Mol Biol Cell (2004) 1.13
The tumour-associated antigen L6 (L6-Ag) is recruited to the tetraspanin-enriched microdomains: implication for tumour cell motility. J Cell Sci (2008) 1.11
Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways. Oncogene (2012) 1.11
The tetraspanin CD63 enhances the internalization of the H,K-ATPase beta-subunit. Proc Natl Acad Sci U S A (2003) 1.11
Tetraspanin CD151 mediates papillomavirus type 16 endocytosis. J Virol (2013) 1.11
N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1. J Biol Chem (2009) 1.10
Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysis. Mol Biol Cell (2009) 1.09
The single subunit transmembrane E3 ligase gene related to anergy in lymphocytes (GRAIL) captures and then ubiquitinates transmembrane proteins across the cell membrane. J Biol Chem (2008) 1.09
Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin beta1 and CD63. Mol Cell Biol (2010) 1.08
CD9 tetraspanin generates fusion competent sites on the egg membrane for mammalian fertilization. Proc Natl Acad Sci U S A (2011) 1.07
The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS Pathog (2009) 1.05
Cross talk between tetanus neurotoxin-insensitive vesicle-associated membrane protein-mediated transport and L1-mediated adhesion. Mol Biol Cell (2003) 1.03
Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Proc Natl Acad Sci U S A (2002) 1.02
Cell-matrix adhesion of podocytes in physiology and disease. Nat Rev Nephrol (2013) 1.02
A novel therapeutic strategy with anti-CD9 antibody in gastric cancers. J Gastroenterol (2009) 1.01
Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies. Br J Pharmacol (2014) 1.01
Signal transduction during activation and inhibition of natural killer cells. Curr Protoc Immunol (2010) 1.00
The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking. Neuron (2012) 0.98
The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development (2009) 0.97
Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis. J Bone Miner Res (2013) 0.97
Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells. J Cell Sci (2012) 0.96
Gangliosides play an important role in the organization of CD82-enriched microdomains. Biochem J (2006) 0.96
Tetraspanin CD151 stimulates adhesion-dependent activation of Ras, Rac, and Cdc42 by facilitating molecular association between β1 integrins and small GTPases. J Biol Chem (2012) 0.95
CD151 restricts the α6 integrin diffusion mode. J Cell Sci (2012) 0.95
CD82 endocytosis and cholesterol-dependent reorganization of tetraspanin webs and lipid rafts. FASEB J (2009) 0.95
Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival. Infect Immun (2012) 0.94
CD81 regulates cell migration through its association with Rac GTPase. Mol Biol Cell (2012) 0.94
Expression pattern and regulation of genes differ between fibroblasts of adhesion and normal human peritoneum. Reprod Biol Endocrinol (2005) 0.93
TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet (2013) 0.93
Down-regulation of TM4SF is associated with the metastatic potential of gastric carcinoma TM4SF members in gastric carcinoma. World J Surg Oncol (2011) 0.93
Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo. J Exp Med (2005) 0.92
Determination of protein regions responsible for interactions of amelogenin with CD63 and LAMP1. Biochem J (2007) 0.92
Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist. PLoS One (2012) 0.92
CD151 in cancer progression and metastasis: a complex scenario. Lab Invest (2013) 0.91
CD9 clustering and formation of microvilli zippers between contacting cells regulates virus-induced cell fusion. Traffic (2008) 0.90
Tetraspanin is required for generation of reactive oxygen species by the dual oxidase system in Caenorhabditis elegans. PLoS Genet (2012) 0.89
Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and Src. PLoS One (2011) 0.89
The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding. Oncotarget (2015) 0.89
Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks. Prog Lipid Res (2013) 0.89
Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin α6β4. Cell Mol Life Sci (2012) 0.88
Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells. Immunology (2009) 0.87
Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. Br J Cancer (2013) 0.86
Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini. PLoS Negl Trop Dis (2012) 0.86
CD98 activation increases surface expression and clusteringof beta1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms. Exp Mol Med (2008) 0.86
Exosomes released from breast cancer carcinomas stimulate cell movement. PLoS One (2015) 0.86
Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5. Genomics Inform (2014) 0.85
Sarcospan: a small protein with large potential for Duchenne muscular dystrophy. Skelet Muscle (2013) 0.85
Integrin Regulation of Epidermal Functions in Wounds. Adv Wound Care (New Rochelle) (2014) 0.85
Evolution of metazoan cell junction proteins: the scaffold protein MAGI and the transmembrane receptor tetraspanin in the demosponge Suberites domuncula. J Mol Evol (2004) 0.85
Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitro. J Biol Chem (2012) 0.85
Cross talk between the TM4SF5/focal adhesion kinase and the interleukin-6/STAT3 pathways promotes immune escape of human liver cancer cells. Mol Cell Biol (2014) 0.85
Tetraspanins in Cell Migration. Cell Adh Migr (2015) 0.85
The important role of T cells and receptor expression in Sjögren's syndrome. Scand J Immunol (2013) 0.84
Tetraspanins in mast cells. Front Immunol (2012) 0.84
Focal Contact and Hemidesmosomal Proteins in Keratinocyte Migration and Wound Repair. Adv Wound Care (New Rochelle) (2014) 0.83
The CD9/CD81 tetraspanin complex and tetraspanin CD151 regulate α3β1 integrin-dependent tumor cell behaviors by overlapping but distinct mechanisms. PLoS One (2013) 0.83