Published in Mol Biol Cell on December 21, 2012
Tetraspanins in extracellular vesicle formation and function. Front Immunol (2014) 1.56
The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. J Biol Chem (2013) 1.10
Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies. Br J Pharmacol (2014) 1.01
HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins. J Virol (2014) 0.99
Interactions between cancer cells and normal cells via miRNAs in extracellular vesicles. Cell Mol Life Sci (2015) 0.87
CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses. Mol Cell Biol (2013) 0.86
Tetraspanins in Cell Migration. Cell Adh Migr (2015) 0.85
Tetraspanins CD9 and CD151 at the immune synapse support T-cell integrin signaling. Eur J Immunol (2014) 0.81
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Magnetic Resonance Imaging of Atherosclerosis Using CD81-Targeted Microparticles of Iron Oxide in Mice. Biomed Res Int (2015) 0.75
Curcumin modulates chronic myelogenous leukemia exosomes composition and affects angiogenic phenotype via exosomal miR-21. Oncotarget (2016) 0.75
Function and Dynamics of Tetraspanins during Antigen Recognition and Immunological Synapse Formation. Front Immunol (2016) 0.75
Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. Mol Cancer Res (2016) 0.75
Tspan2: a tetraspanin protein involved in oligodendrogenesis and cancer metastasis. Biochem Soc Trans (2017) 0.75
Tetraspanins Function as Regulators of Cellular Signaling. Front Cell Dev Biol (2017) 0.75
CD81 association with SAMHD1 enhances HIV-1 reverse transcription by increasing dNTP levels. Nat Microbiol (2017) 0.75
Rho and Rac take center stage. Cell (2004) 10.64
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Simple approach to micropattern cells on common culture substrates by tuning substrate wettability. Tissue Eng (2004) 2.13
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Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol (2008) 1.75
Detecting protein complexes in living cells from laser scanning confocal image sequences by the cross correlation raster image spectroscopy method. Biophys J (2009) 1.72
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinase. Biochem J (2000) 1.61
Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. Blood (2004) 1.56
Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro. Blood (2006) 1.53
Statistical model for large-scale peptide identification in databases from tandem mass spectra using SEQUEST. Anal Chem (2004) 1.50
EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins. J Biol Chem (2006) 1.50
Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood (2008) 1.37
Syntenin-1 is a new component of tetraspanin-enriched microdomains: mechanisms and consequences of the interaction of syntenin-1 with CD63. Mol Cell Biol (2006) 1.32
Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway. J Cell Sci (2010) 1.31
A refined method to calculate false discovery rates for peptide identification using decoy databases. J Proteome Res (2009) 1.31
CD151 regulates epithelial cell-cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization. J Cell Biol (2003) 1.26
Homophilic interactions of Tetraspanin CD151 up-regulate motility and matrix metalloproteinase-9 expression of human melanoma cells through adhesion-dependent c-Jun activation signaling pathways. J Biol Chem (2006) 1.23
Tetraspanins are localized at motility-related structures and involved in normal human keratinocyte wound healing migration. J Invest Dermatol (2000) 1.19
Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions. Biophys J (2011) 1.19
Tetraspanin CD151 regulates RhoA activation and the dynamic stability of carcinoma cell-cell contacts. J Cell Sci (2009) 1.17
Properties of average score distributions of SEQUEST: the probability ratio method. Mol Cell Proteomics (2008) 1.15
Hepatitis C virus E2 and CD81 interaction may be associated with altered trafficking of dendritic cells in chronic hepatitis C. Hepatology (2006) 1.13
Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity. Cell Immunol (1997) 1.12
Tetraspanins in intercellular adhesion of polarized epithelial cells: spatial and functional relationship to integrins and cadherins. J Cell Sci (2001) 1.10
Integrin alpha 6A beta 1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate. Mol Biol Cell (1997) 1.08
Role of tetraspanins CD9 and CD151 in primary melanocyte motility. J Invest Dermatol (2005) 1.07
Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells. Mol Cell Proteomics (2009) 1.06
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells. Blood (2008) 1.05
Tetraspanin CD81 is linked to ERK/MAPKinase signaling by Shc in liver tumor cells. Oncogene (2004) 1.04
A robust method for quantitative high-throughput analysis of proteomes by 18O labeling. Mol Cell Proteomics (2010) 1.03
CD81 associates with 14-3-3 in a redox-regulated palmitoylation-dependent manner. J Biol Chem (2004) 1.02
CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration. Blood (2011) 0.99
Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement. Mol Biol Cell (2001) 0.98
The tetraspanin CD151 regulates cell morphology and intracellular signaling on laminin-511. FEBS J (2008) 0.98
Tetraspanins and intercellular interactions. Microcirculation (2001) 0.97
Targeting tetraspanins in cancer. Expert Opin Ther Targets (2012) 0.96
Tetraspanin CD81-regulated cell motility plays a critical role in intrahepatic metastasis of hepatocellular carcinoma. Gastroenterology (2008) 0.96
Functional interplay between tetraspanins and proteases. Cell Mol Life Sci (2011) 0.95
Double deficiency of tetraspanins CD9 and CD81 alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice. J Biol Chem (2008) 0.94
Tetraspanin CD81 is required for Listeria monocytogenes invasion. Infect Immun (2009) 0.91
alpha2beta1 integrin controls association of Rac with the membrane and triggers quiescence of endothelial cells. J Cell Sci (2010) 0.85
The tetraspanin KAI1/CD82 is expressed by late-lineage oligodendrocyte precursors and may function to restrict precursor migration and promote oligodendrocyte differentiation and myelination. J Neurosci (2009) 0.85
Regulation of NK cell trafficking by CD81. Eur J Immunol (2009) 0.84
Targeting the tetraspanin CD81 blocks monocyte transmigration and ameliorates EAE. Neurobiol Dis (2008) 0.84
Cell migration: integrating signals from front to back. Science (2003) 29.13
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol (2010) 7.27
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat Commun (2011) 5.95
Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Nat Cell Biol (2008) 5.87
Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med (2003) 5.01
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics. J Cell Biol (2006) 3.15
Integrins in cell migration. Cold Spring Harb Perspect Biol (2011) 3.15
Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature (2016) 2.98
Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell (2002) 2.94
Integrins in cell migration--the actin connection. J Cell Sci (2009) 2.88
CD69 is an immunoregulatory molecule induced following activation. Trends Immunol (2005) 2.83
Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes. Trends Cell Biol (2009) 2.82
HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions. Trends Cell Biol (2008) 2.71
Probing the integrin-actin linkage using high-resolution protein velocity mapping. J Cell Sci (2006) 2.61
Intercellular communication: diverse structures for exchange of genetic information. Nat Rev Mol Cell Biol (2012) 2.28
Role of the cytoskeleton during leukocyte responses. Nat Rev Immunol (2004) 2.11
GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration. J Cell Sci (2002) 1.98
HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization. Immunity (2004) 1.82
S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities. Proc Natl Acad Sci U S A (2005) 1.77
Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol (2008) 1.75
MTOC translocation modulates IS formation and controls sustained T cell signaling. J Cell Biol (2008) 1.75
ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1. Immunity (2002) 1.73
Directional persistence of EGF-induced cell migration is associated with stabilization of lamellipodial protrusions. Biophys J (2005) 1.70
Reducing background fluorescence reveals adhesions in 3D matrices. Nat Cell Biol (2011) 1.69
In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding. Eur J Immunol (2012) 1.63
Angiogenesis in chronic inflammatory liver disease. Hepatology (2004) 1.57
Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. Blood (2004) 1.56
Antitumoral effect of a vaccination procedure with an autologous hemoderivative. Cancer Biol Ther (2003) 1.50
Statistical model for large-scale peptide identification in databases from tandem mass spectra using SEQUEST. Anal Chem (2004) 1.50
EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins. J Biol Chem (2006) 1.50
ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells. J Cell Biol (2002) 1.48
Tetraspanins CD9 and CD81 modulate HIV-1-induced membrane fusion. J Immunol (2006) 1.48
Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis. J Clin Endocrinol Metab (2009) 1.45
The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL-1 through ERM proteins. Eur J Immunol (2011) 1.45
Specific targeting of human inflamed endothelium and in situ vascular tissue transfection by the use of ultrasound contrast agents. JACC Cardiovasc Imaging (2009) 1.42
CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. J Clin Invest (2003) 1.41
Cutting edge: dynamic redistribution of tetraspanin CD81 at the central zone of the immune synapse in both T lymphocytes and APC. J Immunol (2002) 1.41
Membrane type 1-matrix metalloproteinase is involved in migration of human monocytes and is regulated through their interaction with fibronectin or endothelium. Blood (2005) 1.40
Caveolae are a novel pathway for membrane-type 1 matrix metalloproteinase traffic in human endothelial cells. Mol Biol Cell (2003) 1.39
Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection. Mol Biol Cell (2005) 1.37
Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells. J Cell Biol (2011) 1.36
Membrane lateral diffusion and capture of CFTR within transient confinement zones. Biophys J (2006) 1.36
Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes. J Cell Sci (2008) 1.35
Improved method for differential expression proteomics using trypsin-catalyzed 18O labeling with a correction for labeling efficiency. Mol Cell Proteomics (2007) 1.33
A refined method to calculate false discovery rates for peptide identification using decoy databases. J Proteome Res (2009) 1.31
VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses. Proc Natl Acad Sci U S A (2004) 1.31
Transcriptional activation by AP-2alpha is modulated by the oncogene DEK. Nucleic Acids Res (2003) 1.31
Enhanced antitumor immunity in mice deficient in CD69. J Exp Med (2003) 1.29
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell (2006) 1.29
Role of the von Hippel-Lindau tumor suppressor gene in the formation of beta1-integrin fibrillar adhesions. Cancer Res (2002) 1.27
Relevance of CD6-mediated interactions in T cell activation and proliferation. J Immunol (2004) 1.27
Analyzing the first drafts of the human proteome. J Proteome Res (2014) 1.27
Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions. Immunol Rev (2007) 1.26
CD69: an unexpected regulator of TH17 cell-driven inflammatory responses. Sci Signal (2011) 1.26
Transfer of extracellular vesicles during immune cell-cell interactions. Immunol Rev (2013) 1.25
Regulation of microtubule-organizing center orientation and actomyosin cytoskeleton rearrangement during immune interactions. Immunol Rev (2002) 1.25
Blockade of NFAT activation by the second calcineurin binding site. J Biol Chem (2006) 1.24
Role of Fyn in the rearrangement of tubulin cytoskeleton induced through TCR. J Immunol (2006) 1.20
Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1alpha. J Cell Sci (2007) 1.20
Self-renewing human bone marrow mesenspheres promote hematopoietic stem cell expansion. Cell Rep (2013) 1.20
Molecular cues guiding inflammatory responses. Cardiovasc Res (2010) 1.19
The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse. EMBO J (2011) 1.19
Cell migration: an overview. Methods Mol Biol (2011) 1.19
Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions. Biophys J (2011) 1.19
A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting. J Biol Chem (2002) 1.17
The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells. Sci Signal (2012) 1.17
CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation. Mol Cell Biol (2010) 1.17
Properties of average score distributions of SEQUEST: the probability ratio method. Mol Cell Proteomics (2008) 1.15
A juxta-membrane amino acid sequence of P-selectin glycoprotein ligand-1 is involved in moesin binding and ezrin/radixin/moesin-directed targeting at the trailing edge of migrating lymphocytes. Eur J Immunol (2002) 1.14
Regulatory T cells in human autoimmune thyroid disease. J Clin Endocrinol Metab (2006) 1.14
G protein-coupled receptor kinase 2 positively regulates epithelial cell migration. EMBO J (2008) 1.14
Wound healing with electric potential. N Engl J Med (2007) 1.13
Adhesion dynamics at a glance. J Cell Sci (2011) 1.13
Role of ICAM-3 in the initial interaction of T lymphocytes and APCs. Nat Immunol (2002) 1.13
Endothelial nitric oxide synthase regulates T cell receptor signaling at the immunological synapse. Immunity (2006) 1.13
Recruitment of transferrin receptor to immunological synapse in response to TCR engagement. J Immunol (2004) 1.12
Integrating adhesion, protrusion, and contraction during cell migration. Cell (2006) 1.12
Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding. J Immunol (2007) 1.11
The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. J Biol Chem (2013) 1.10
Synaptic clusters of MHC class II molecules induced on DCs by adhesion molecule-mediated initial T-cell scanning. Mol Biol Cell (2005) 1.10
CD69 limits the severity of cardiomyopathy after autoimmune myocarditis. Circulation (2010) 1.09
The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells. J Biol Chem (2002) 1.09
Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor. J Immunol (2009) 1.07
Role of tetraspanins CD9 and CD151 in primary melanocyte motility. J Invest Dermatol (2005) 1.07
Is CD69 an effective brake to control inflammatory diseases? Trends Mol Med (2013) 1.06
Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells. Mol Cell Proteomics (2009) 1.06
Selective inactivation of p27(Kip1) in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis. Blood (2003) 1.06
Molecular basis of leukocyte-endothelium interactions during the inflammatory response. Rev Esp Cardiol (2009) 1.05
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells. Blood (2008) 1.05
HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5. Mol Cell (2012) 1.05
A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis. J Immunol (2002) 1.05