Published in J Clin Invest on January 01, 2002
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 14.33
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med (2006) 8.41
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med (2004) 8.00
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J Exp Med (2004) 6.48
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity (2008) 6.08
The PD-1 pathway in tolerance and autoimmunity. Immunol Rev (2010) 5.99
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet (2007) 5.68
Going both ways: immune regulation via CD1d-dependent NKT cells. J Clin Invest (2004) 5.16
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med (2003) 4.39
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med (2004) 4.35
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases. Nat Rev Immunol (2010) 3.69
CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med (2004) 3.57
L2L: a simple tool for discovering the hidden significance in microarray expression data. Genome Biol (2005) 3.27
Human T regulatory cell therapy: take a billion or so and call me in the morning. Immunity (2009) 3.21
Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice. Proc Natl Acad Sci U S A (2002) 2.45
Immune cell crosstalk in type 1 diabetes. Nat Rev Immunol (2010) 2.26
Presumed guilty: natural killer T cell defects and human disease. Nat Rev Immunol (2011) 2.21
B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity. Ann Neurol (2010) 2.17
The role of NKT cells in tumor immunity. Adv Cancer Res (2008) 2.05
Testing the NKT cell hypothesis of human IDDM pathogenesis. J Clin Invest (2002) 1.98
Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala). J Clin Invest (2003) 1.95
Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis. Blood (2004) 1.90
The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A (2008) 1.85
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J Exp Med (2005) 1.79
Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells. Proc Natl Acad Sci U S A (2004) 1.69
Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J Lipid Res (2011) 1.69
Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells. Proc Natl Acad Sci U S A (2005) 1.67
Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology (2007) 1.63
Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura. Blood (2008) 1.63
Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3. Proc Natl Acad Sci U S A (2005) 1.57
Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions. PLoS One (2007) 1.51
Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes. Clin Exp Immunol (2008) 1.44
Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia. Blood (2007) 1.44
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2. J Exp Med (2004) 1.43
Dishing the dirt on asthma: What we can learn from poor hygiene. Biologics (2007) 1.40
Myeloid-derived suppressor cells prevent type 1 diabetes in murine models. J Immunol (2010) 1.38
Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells. Immunology (2007) 1.35
Autologous umbilical cord blood infusion for type 1 diabetes. Exp Hematol (2008) 1.34
Serum IL-1beta, IL-2, and IL-6 in insulin-dependent diabetic children. Mediators Inflamm (2006) 1.34
Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients. Clin Exp Immunol (2007) 1.32
A model for personalized in vivo analysis of human immune responsiveness. Sci Transl Med (2012) 1.27
Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes. J Immunol (2008) 1.27
A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes. Immunogenetics (2003) 1.26
The contrasting roles of NKT cells in tumor immunity. Curr Mol Med (2009) 1.24
Development of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7. Proc Natl Acad Sci U S A (2004) 1.21
Lipid-antigen presentation by CD1d(+) B cells is essential for the maintenance of invariant natural killer T cells. Immunity (2012) 1.21
Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants. BMC Immunol (2009) 1.20
Enteropathy precedes type 1 diabetes in the BB rat. Gut (2004) 1.19
The IL-2/CD25 pathway determines susceptibility to T1D in humans and NOD mice. J Clin Immunol (2008) 1.19
Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation. PLoS One (2009) 1.19
Enrichment of CD4+ CD25high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids. Ann Rheum Dis (2006) 1.17
Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice. PLoS One (2009) 1.16
Immunopathogenic mechanisms in tourette syndrome: A critical review. Mov Disord (2009) 1.16
Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action. CNS Drugs (2011) 1.15
At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction. PLoS One (2007) 1.15
The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forward. J Child Adolesc Psychopharmacol (2010) 1.13
An update on the use of NOD mice to study autoimmune (Type 1) diabetes. Expert Rev Clin Immunol (2010) 1.13
Medical applications of leukocyte surface molecules--the CD molecules. Mol Med (2007) 1.12
Approaches in type 1 diabetes research: A status report. Int J Diabetes Dev Ctries (2009) 1.08
Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system. Arthritis Res Ther (2003) 1.05
Distinct roles of helper T-cell subsets in a systemic autoimmune disease. Blood (2008) 1.04
The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in non-obese diabetic mice. Clin Exp Immunol (2006) 1.03
Circulating and thymic CD4 CD25 T regulatory cells in myasthenia gravis: effect of immunosuppressive treatment. Immunology (2005) 1.03
Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity. Arthritis Res Ther (2008) 1.03
Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in nonobese diabetic mice. J Exp Med (2004) 1.02
A novel pancreatic β-cell targeting bispecific-antibody (BsAb) can prevent the development of type 1 diabetes in NOD mice. Clin Immunol (2014) 1.01
Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality? Clin Exp Immunol (2013) 0.98
Early treatment of NOD mice with B7-H4 reduces the incidence of autoimmune diabetes. Diabetes (2011) 0.96
Cytokines and other immunological biomarkers in children's environmental health studies. Toxicol Lett (2007) 0.96
Alteration of the relative levels of iNKT cell subsets is associated with chronic mycobacterial infections. Clin Immunol (2008) 0.95
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice. J Exp Med (2012) 0.95
Repetitive pertussis toxin promotes development of regulatory T cells and prevents central nervous system autoimmune disease. PLoS One (2010) 0.93
Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis. BMC Syst Biol (2011) 0.91
Protective role of programmed death 1 ligand 1 (PD-L1)in nonobese diabetic mice: the paradox in transgenic models. Diabetes (2008) 0.90
Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice. Rev Diabet Stud (2010) 0.89
Dietary gluten alters the balance of pro-inflammatory and anti-inflammatory cytokines in T cells of BALB/c mice. Immunology (2013) 0.89
T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives. Clin Dev Immunol (2011) 0.89
Naturally-occurring regulatory T cells are increased in inflamed portal tracts with cholangiopathy in primary biliary cirrhosis. J Clin Pathol (2006) 0.89
Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes. J Immunol (2010) 0.88
Agent based modeling of Treg-Teff cross regulation in relapsing-remitting multiple sclerosis. BMC Bioinformatics (2013) 0.88
Mechanisms of human autoimmunity. J Clin Invest (2015) 0.87
Impaired thymic export and increased apoptosis account for regulatory T cell defects in patients with non-ST segment elevation acute coronary syndrome. J Biol Chem (2012) 0.87
Mechanistic links between gut microbial community dynamics, microbial functions and metabolic health. World J Gastroenterol (2014) 0.86
Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes. Diabetes (2011) 0.86
Natural killer cells as indispensable players and therapeutic targets in autoimmunity. Autoimmunity (2010) 0.86
APC activation restores functional CD4(+)CD25(+) regulatory T cells in NOD mice that can prevent diabetes development. PLoS One (2008) 0.86
Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus. Int J Mol Sci (2015) 0.86
CD4 T cell differentiation in type 1 diabetes. Clin Exp Immunol (2015) 0.86
Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes. Am J Ther (2005) 0.86
PD-1 marks dysfunctional regulatory T cells in malignant gliomas. JCI Insight (2016) 0.85
Death pathways in T cell homeostasis and their role in autoimmune diabetes. Rev Diabet Stud (2006) 0.85
Impact of dietary gluten on regulatory T cells and Th17 cells in BALB/c mice. PLoS One (2012) 0.85
NKT Cell Subsets Can Exert Opposing Effects in Autoimmunity, Tumor Surveillance and Inflammation. Curr Immunol Rev (2012) 0.85
Plasmacytoid precursor dendritic cells from NOD mice exhibit impaired function: are they a component of diabetes pathogenesis? Diabetes (2008) 0.85
Lower frequency of CD62L(high) and higher frequency of TNFR2(+) Tregs are associated with inflammatory conditions in type 1 diabetic patients. Mediators Inflamm (2011) 0.85
Regulation of type 1 diabetes, tuberculosis, and asthma by parasites. J Mol Med (Berl) (2009) 0.85
Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus. Clin Exp Immunol (2013) 0.84
Harnessing memory adaptive regulatory T cells to control autoimmunity in type 1 diabetes. J Mol Cell Biol (2011) 0.84
Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development. Pediatr Rheumatol Online J (2008) 0.83
High-dose cholecalciferol supplementation significantly increases peripheral CD4⁺ Tregs in healthy adults without negatively affecting the frequency of other immune cells. Eur J Nutr (2013) 0.83
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med (1998) 19.03
Functional diversity of helper T lymphocytes. Nature (1996) 18.09
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity (2000) 15.44
Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science (1997) 8.95
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med (2001) 7.86
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med (1994) 7.35
CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol (1998) 7.31
Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain. J Exp Med (1993) 4.80
Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur J Immunol (2001) 4.58
Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature (1998) 4.10
Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cells. J Exp Med (1997) 3.74
Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J Exp Med (1995) 3.58
Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat Med (2001) 3.56
The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat Med (2001) 3.39
Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice. J Immunol (1996) 2.83
Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. J Exp Med (1998) 2.75
Selective reduction of T cells bearing invariant V alpha 24J alpha Q antigen receptor in patients with systemic sclerosis. J Exp Med (1995) 2.63
CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site. J Exp Med (1999) 2.53
Dendritic cell lineage, plasticity and cross-regulation. Nat Immunol (2001) 2.43
Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1. J Immunol (1997) 2.28
Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol (2000) 2.24
Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation? Diabetes (1994) 2.14
NKT cells are phenotypically and functionally diverse. Eur J Immunol (1999) 1.97
Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proc Natl Acad Sci U S A (1995) 1.94
Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice. Diabetes (1996) 1.85
Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice. J Exp Med (1994) 1.82
Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice. Diabetes (1997) 1.74
Interferon expression in the pancreases of patients with type I diabetes. Diabetes (1995) 1.69
Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups. Hum Mol Genet (1997) 1.65
Close phenotypic and functional similarities between human and murine alphabeta T cells expressing invariant TCR alpha-chains. J Immunol (1997) 1.63
Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. J Immunol (2000) 1.63
Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation. J Immunol (2001) 1.61
Positive selection of invariant V alpha 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells. Proc Natl Acad Sci U S A (1995) 1.57
Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat. Diabetologia (1987) 1.55
NKT cells and tumor immunity--a double-edged sword. Nat Immunol (2000) 1.53
IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function. J Immunol (1997) 1.48
Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis. J Immunol (1991) 1.45
The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis. Eur J Immunol (2001) 1.37
Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci. J Immunol (2000) 1.37
Insulitis in type 1 (insulin-dependent) diabetes mellitus in man--macrophages, lymphocytes, and interferon-gamma containing cells. J Pathol (1991) 1.34
Liver NK1.1+ CD4+ alpha beta T cells activated by IL-12 as a major effector in inhibition of experimental tumor metastasis. J Immunol (1996) 1.32
Decreased cell-mediated immunity in patients with non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract (1995) 1.27
Tolerance mechanism in experimental ovarian and gastric autoimmune diseases. J Immunol (1992) 1.27
Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. I. Requirement of Lyt-1 dull L3T4 bright normal T cells for the induction of thyroiditis. J Immunol (1988) 1.26
Acquired defect in interleukin-2 production in patients with type I diabetes mellitus. N Engl J Med (1986) 1.25
Multiple differences in gene expression in regulatory Valpha 24Jalpha Q T cells from identical twins discordant for type I diabetes. Proc Natl Acad Sci U S A (2000) 1.22
IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice. J Immunol (1995) 1.15
Impaired yield, phenotype, and function of monocyte-derived dendritic cells in humans at risk for insulin-dependent diabetes. J Immunol (1998) 1.13
Polymorphism of human CD1 genes. Tissue Antigens (1999) 1.09
Natural killer (NK) T cells are significantly decreased in the peripheral blood of patients with rheumatoid arthritis (RA). Clin Exp Immunol (1999) 1.08
Splenic macrophages from the NOD mouse are defective in the ability to present antigen. Diabetes (1998) 1.07
A defect in bone marrow derived dendritic cell maturation in the nonobesediabetic mouse. Clin Exp Immunol (2001) 1.05
Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives. J Autoimmun (1999) 1.01
Interleukin 2 and soluble interleukin 2-receptor secretion defect in vitro in newly diagnosed type I diabetic patients. Diabetes (1989) 0.97
Cytokine expression in unstimulated PBMC of children with type 1 diabetes and subjects positive for diabetes-associated autoantibodies. Scand J Immunol (2001) 0.97
Short-term hyperglycemia induces lymphopenia and lymphocyte subset redistribution. Life Sci (2001) 0.94
Organ-specific autoimmunity. Curr Opin Immunol (1997) 0.92
T lymphopenia in genetically obese-diabetic Wistar fatty rats: effects of body weight reduction on T cells. Metabolism (2000) 0.91
Resistance of T-cells to apoptosis in autoimmune diabetic (NOD) mice is increased early in life and is associated with dysregulated expression of Bcl-x. Diabetologia (1998) 0.89
T lymphopenia in obese diabetic (db/db) mice is non-selective and thymus independent. Life Sci (1998) 0.89
Noncanonical Valpha24JalphaQ T cells with conservative alpha chain CDR3 region amino acid substitutions are restricted by CD1d. Hum Immunol (1999) 0.88
Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients. J Immunol (2000) 0.85
Similar alterations of lymphocyte subpopulations in type I and type II diabetes. Neth J Med (1993) 0.84
Influence of blood glucose levels on peripheral lymphocytes in patients with diabetes mellitus. Diabetes Res (1992) 0.83
Dissociated production of interleukin-2 and immune gamma-interferon by phytohaemoagglutinin stimulated peripheral mononuclear cells in type 1 (insulin-dependent) diabetes. J Clin Lab Immunol (1988) 0.80
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J Clin Invest (2004) 5.14
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J Exp Med (2010) 3.93
Adaptive genic evolution in the Drosophila genomes. Proc Natl Acad Sci U S A (2007) 2.56
Identifying smokers with a medical extraction system. J Am Med Inform Assoc (2007) 2.54
CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung. Nat Med (2002) 2.22
Similarities and differences between selective and nonselective BAFF blockade in murine SLE. J Clin Invest (2006) 2.05
Prevalence and clinical features of type 1.5 diabetes mellitus in children. J Pediatr Endocrinol Metab (2007) 2.02
Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death. Cancer Cell (2011) 1.95
Disseminated varicella infection due to the vaccine strain of varicella-zoster virus, in a patient with a novel deficiency in natural killer T cells. J Infect Dis (2003) 1.91
High speed, wide velocity dynamic range Doppler optical coherence tomography (Part I): System design, signal processing, and performance. Opt Express (2003) 1.78
The prevalence of non-alcoholic fatty liver disease and metabolic syndrome in obese children. J Pediatr Endocrinol Metab (2011) 1.60
Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes. Sci Transl Med (2012) 1.59
Prevalence of vitamin D insufficiency in obese children and adolescents. J Pediatr Endocrinol Metab (2007) 1.58
Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. J Exp Med (2005) 1.57
Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes. J Clin Endocrinol Metab (2003) 1.55
Insulin resistance syndrome in children. J Clin Endocrinol Metab (2004) 1.55
Real-life utilization of real-time continuous glucose monitoring: the complete picture. J Diabetes Sci Technol (2011) 1.52
CD1d function is regulated by microsomal triglyceride transfer protein. Nat Med (2004) 1.49
Effect of metformin and rosiglitazone in a prepubertal boy with Alström syndrome. J Pediatr Endocrinol Metab (2007) 1.45
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proc Natl Acad Sci U S A (2009) 1.44
CD1d and invariant NKT cells at the human maternal-fetal interface. Proc Natl Acad Sci U S A (2002) 1.30
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis. Hepatology (2008) 1.27
Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling. Exp Cell Res (2006) 1.24
Clinical, hormonal and cytogenetic evaluation of 46,XX males and review of the literature. J Pediatr Endocrinol Metab (2005) 1.24
Role of CD1d in coxsackievirus B3-induced myocarditis. J Immunol (2003) 1.22
High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamics of Xenopus laevis. Opt Express (2003) 1.21
The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase. Mol Cell Biol (2006) 1.17
Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk. J Biomed Opt (2004) 1.17
Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity. Nat Immunol (2011) 1.14
Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery. J Thorac Cardiovasc Surg (2009) 1.12
High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts. Opt Express (2003) 1.12
Proximity-induced catalysis by the protein kinase ERK2. J Am Chem Soc (2005) 1.08
Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO J (2006) 1.08
Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis. Gastroenterology (2012) 1.06
Control of NKT cell differentiation by tissue-specific microenvironments. J Immunol (2003) 1.05
Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. J Allergy Clin Immunol (2006) 1.04
The clinical and molecular heterogeneity of 17βHSD-3 enzyme deficiency. Horm Res Paediatr (2010) 1.01
CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection. Immunology (2003) 1.01
Clinical case seminar: a novel LHX3 mutation presenting as combined pituitary hormonal deficiency. J Clin Endocrinol Metab (2006) 1.01
Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus--a new surrogate measure of non-progression? Pediatr Diabetes (2004) 1.00
Phenotypic features associated with mutations in steroidogenic acute regulatory protein. J Clin Endocrinol Metab (2005) 1.00
Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity. J Hypertens (2005) 0.99
The analysis of systemic tolerance elicited by antigen inoculation into the vitreous cavity: vitreous cavity-associated immune deviation. Immunology (2005) 0.99
Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development. Mol Cell Endocrinol (2007) 0.98
Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clin Immunol (2008) 0.98
Blood Pressure over Height Ratios: Simple and Accurate Method of Detecting Elevated Blood Pressure in Children. Int J Pediatr (2012) 0.97
Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care. Horm Res Paediatr (2016) 0.97
Severe mandibuloacral dysplasia-associated lipodystrophy and progeria in a young girl with a novel homozygous Arg527Cys LMNA mutation. J Clin Endocrinol Metab (2008) 0.97
Atypical findings in three patients with Pai syndrome and literature review. Am J Med Genet A (2012) 0.96
Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus. J Biol Chem (2011) 0.96
Synthesis and characterization of highly photoresponsive fullerenyl dyads with a close chromophore antenna-C(60) contact and effective photodynamic potential. J Mater Chem (2010) 0.95
Lethal photosensitization of periodontal pathogens by a red-filtered Xenon lamp in vitro. J Periodontal Res (2003) 0.94
Early pulmonary cytokine and chemokine responses in mice immunized with three different vaccines against Mycobacterium tuberculosis determined by PCR array. Clin Vaccine Immunol (2008) 0.94
Expanding the spectrum of mutations in GH1 and GHRHR: genetic screening in a large cohort of patients with congenital isolated growth hormone deficiency. J Clin Endocrinol Metab (2009) 0.93
GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1. J Clin Endocrinol Metab (2011) 0.92
Linkage disequilibrium sharing and haplotype-tagged SNP portability between populations. Proc Natl Acad Sci U S A (2006) 0.92
Soluble nonclassical HLA generated by the metalloproteinase pathway. Hum Immunol (2003) 0.91
Effects of protease inhibitors on glucose tolerance, lipid metabolism, and body composition in children and adolescents infected with human immunodeficiency virus. Endocr Pract (2006) 0.91
Donor splice mutation in the 11beta-hydroxylase (CypllB1) gene resulting in sex reversal: a case report and review of the literature. J Pediatr Endocrinol Metab (2006) 0.91
Complete androgen insensitivity syndrome is frequently due to premature stop codons in exon 1 of the androgen receptor gene: an international collaborative report of 13 new mutations. Fertil Steril (2009) 0.90
Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury. Am J Respir Cell Mol Biol (2013) 0.89
Interleukin-2 treatment for persistent cryptococcal meningitis in a child with idiopathic CD4(+) T lymphocytopenia. Allergy Asthma Proc (2008) 0.88
Insulin pump therapy from the time of diagnosis of type 1 diabetes. Diabetes Technol Ther (2006) 0.88
Evaluation of genome coverage and fidelity of multiple displacement amplification from single cells by SNP array. Mol Hum Reprod (2009) 0.87
Serum levels of soluble tumor necrosis factor-alpha receptor 2 are linked to insulin resistance and glucose intolerance in children. J Pediatr Endocrinol Metab (2005) 0.87
Phenotypic features of 46, XX females with StAR protein mutations. Pediatr Endocrinol Rev (2007) 0.87
Endothelial function as measured by peripheral arterial tonometry increases during pubertal advancement. Horm Res Paediatr (2011) 0.86
Steroid 21 hydroxylase deficiency congenital adrenal hyperplasia. Pediatr Clin North Am (2011) 0.86
Complications of obesity in childhood. Pediatr Ann (2007) 0.86
An ancient founder mutation in PROKR2 impairs human reproduction. Hum Mol Genet (2012) 0.85
Childhood obesity and insulin resistance. Cell Biochem Biophys (2007) 0.85
Aldosterone-to-renin ratio as a marker for disease severity in 21-hydroxylase deficiency congenital adrenal hyperplasia. J Clin Endocrinol Metab (2006) 0.85
Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes. Ann N Y Acad Sci (2004) 0.85
Isolation and functional use of human NKT cells. Curr Protoc Immunol (2010) 0.84
NKT cell defects in NOD mice suggest therapeutic opportunities. J Autoimmun (2002) 0.84
Insulin resistance, lipodystrophy and cardiometabolic syndrome in HIV/AIDS. Rev Endocr Metab Disord (2013) 0.83
Phenotypic variations in lipoid congenital adrenal hyperplasia. Pediatr Endocrinol Rev (2006) 0.83
Tribochemistry and superlubricity induced by hydrogen ions. Langmuir (2012) 0.83
Basal insulin requirements on continuous subcutaneous insulin infusion during the first 12 months after diagnosis of type 1 diabetes mellitus. J Diabetes Sci Technol (2010) 0.83
Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity. Obesity (Silver Spring) (2013) 0.83
The clinical characteristics and prognosis of Chinese early stage breast cancer patients: a retrospective study. Breast J (2010) 0.83
Superlubricity behavior with phosphoric acid-water network induced by rubbing. Langmuir (2011) 0.82
Superlubricity achieved with mixtures of polyhydroxy alcohols and acids. Langmuir (2013) 0.82
Shaping of iNKT cell repertoire after unrelated cord blood transplantation. Clin Immunol (2010) 0.81
Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity. J Med Chem (2014) 0.81
Superlubricity achieved with mixtures of acids and glycerol. Langmuir (2012) 0.81
Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements. J Immunol (2010) 0.81
Insulin-like growth factor binding protein-1 to screen for insulin resistance in children. Diabetes Technol Ther (2007) 0.80
Steroid 21 hydroxylase deficiency congenital adrenal hyperplasia. Endocrinol Metab Clin North Am (2009) 0.80
Isolated mild clitoral hypertrophy may reveal 46,XY disorders of sex development in infancy due to 17βHSD-3 defect confirmed by molecular analysis. Gynecol Endocrinol (2011) 0.80
Association of hemoglobin levels, CYP3A5, and NR1I3 gene polymorphisms with tacrolimus pharmacokinetics in liver transplant patients. Drug Metab Pharmacokinet (2013) 0.79
Isolated micropenis reveals partial androgen insensitivity syndrome confirmed by molecular analysis. Asian J Androl (2010) 0.79
Markers of ovarian reserve in young girls with Turner's syndrome. Fertil Steril (2010) 0.79
Retinol binding protein 4 is associated with adiposity-related co-morbidity risk factors in children. J Pediatr Endocrinol Metab (2011) 0.79
An unprecedented (3,4,24)-connected heteropolyoxozincate organic framework as heterogeneous crystalline Lewis acid catalyst for biodiesel production. Sci Rep (2013) 0.79
Phenotypic variation of SF1 gene mutations. Adv Exp Med Biol (2011) 0.78
Treatment perspectives in idiopathic short stature with a focus on IGF-I deficiency. Pediatr Endocrinol Rev (2007) 0.78