Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice.

PubWeight™: 2.45‹?› | Rank: Top 2%

🔗 View Article (PMC 129437)

Published in Proc Natl Acad Sci U S A on September 09, 2002

Authors

Ava J Wu1, Hong Hua, Sibyl H Munson, Hugh O McDevitt

Author Affiliations

1: Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Articles citing this

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J Exp Med (2004) 6.48

Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med (2006) 5.88

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood (2006) 4.63

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med (2003) 4.39

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med (2004) 4.35

CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med (2004) 3.57

Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice. J Clin Invest (2004) 2.16

Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetes. Am J Transplant (2012) 2.12

Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes. J Exp Med (2005) 2.05

The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A (2008) 1.85

Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. J Clin Invest (2004) 1.74

The development and function of regulatory T cells. Cell Mol Life Sci (2009) 1.66

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice. J Clin Invest (2007) 1.63

Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes. Sci Transl Med (2013) 1.55

Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia. J Hepatol (2013) 1.54

Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes. Proc Natl Acad Sci U S A (2007) 1.51

T cell killing by tolerogenic dendritic cells protects mice from allergy. J Clin Invest (2011) 1.41

Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells. Immunology (2007) 1.35

Autologous umbilical cord blood infusion for type 1 diabetes. Exp Hematol (2008) 1.34

Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes. J Immunol (2008) 1.27

Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression. PLoS One (2009) 1.20

CD4+ CD25+ Treg: divide and rule? Immunology (2004) 1.11

CD8α+ plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo. Blood (2010) 1.07

Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity. Endocr Rev (2013) 1.05

Suppression of glomerulonephritis in NZB/NZW lupus prone mice by adoptive transfer of ex vivo expanded regulatory T cells. PLoS One (2009) 1.03

Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner. Eur J Immunol (2009) 1.02

The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation. Proc Natl Acad Sci U S A (2005) 0.99

Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells. Proc Natl Acad Sci U S A (2009) 0.97

An early age-related increase in the frequency of CD4+ Foxp3+ cells in BDC2.5NOD mice. Immunology (2007) 0.96

Increased number and function of FoxP3 regulatory T cells during experimental arthritis. Arthritis Rheum (2008) 0.96

Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities. Immunology (2006) 0.96

Anti-TNF-alpha therapies in systemic lupus erythematosus. J Biomed Biotechnol (2010) 0.96

Role of cytokines in thymus- versus peripherally derived-regulatory T cell differentiation and function. Front Immunol (2013) 0.95

Exogenous tumour necrosis factor alpha induces suppression of autoimmune arthritis. Arthritis Res Ther (2008) 0.93

Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome. Arthritis Res Ther (2009) 0.93

Aberrant endometrial features of pregnancy in diabetic NOD mice. Diabetes (2007) 0.93

T regulatory cells: aid or hindrance in the clearance of disease? J Cell Mol Med (2008) 0.93

Immune effects of therapy with Adalimumab in patients with rheumatoid arthritis. Clin Exp Immunol (2005) 0.91

TNF-alpha antagonism generates a population of antigen-specific CD4+CD25+ T cells that inhibit protective immunity in murine histoplasmosis. J Immunol (2008) 0.90

TLR2 signaling improves immunoregulation to prevent type 1 diabetes. Eur J Immunol (2011) 0.89

Evidence for immunological priming and increased frequency of CD4+ CD25+ cord blood T cells in children born to mothers with type 1 diabetes. Clin Exp Immunol (2006) 0.88

Antigen-specific tolerogenic and immunomodulatory strategies for the treatment of autoimmune arthritis. Semin Arthritis Rheum (2008) 0.88

APC activation restores functional CD4(+)CD25(+) regulatory T cells in NOD mice that can prevent diabetes development. PLoS One (2008) 0.86

Regulatory T cells and Atherosclerosis. J Clin Exp Cardiolog (2012) 0.85

Lower frequency of CD62L(high) and higher frequency of TNFR2(+) Tregs are associated with inflammatory conditions in type 1 diabetic patients. Mediators Inflamm (2011) 0.85

Prss16 is not required for T-cell development. Mol Cell Biol (2005) 0.84

Mesenchymal stromal cells improve salivary function and reduce lymphocytic infiltrates in mice with Sjögren's-like disease. PLoS One (2012) 0.84

Mast cells and the adaptive immune response. J Clin Immunol (2008) 0.79

The role of regulatory T cell defects in type I diabetes and the potential of these cells for therapy. Rev Diabet Stud (2005) 0.79

TLR2- and Dectin 1-associated innate immune response modulates T-cell response to pancreatic β-cell antigen and prevents type 1 diabetes. Diabetes (2014) 0.79

Thymus and aging: morphological, radiological, and functional overview. Age (Dordr) (2013) 0.79

Limitations in immunotherapy with CD3 antibodies: comment on the article by Drs. Chatenoud and Bach. Rev Diabet Stud (2006) 0.78

Reversible lacrimal gland-protective regulatory T-cell dysfunction underlies male-specific autoimmune dacryoadenitis in the non-obese diabetic mouse model of Sjögren syndrome. Immunology (2015) 0.78

Novel technologies to engineer graft for tolerance induction. Curr Opin Organ Transplant (2016) 0.78

Regulatory T cells control diabetes without compromising acute anti-viral defense. Clin Immunol (2014) 0.78

Increased T regulatory cells lead to development of Th2 immune response in male SJL mice. Autoimmunity (2010) 0.77

miR-139-5p modulates cortical neuronal migration by targeting Lis1 in a rat model of focal cortical dysplasia. Int J Mol Med (2014) 0.77

Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them? J Immunol (2016) 0.76

Altered connexin 43 expression underlies age-dependent decrease of regulatory T cell suppressor function in nonobese diabetic mice. J Immunol (2015) 0.76

Culture promotes transfer of thyroid epithelial cell hyperplasia and proliferation by reducing regulatory T cell numbers. Cell Immunol (2013) 0.76

Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation. Immunology (2016) 0.76

Alteration of the thymic T cell repertoire by rotavirus infection is associated with delayed type 1 diabetes development in non-obese diabetic mice. PLoS One (2013) 0.75

CCR5 deficiency mitigates the deleterious effects of tumor necrosis factor α antagonism in murine histoplasmosis. J Infect Dis (2012) 0.75

Gene therapy for type 1 diabetes: a novel approach for targeted treatment of autoimmunity. J Clin Invest (2004) 0.75

The islet-resident macrophage is in an inflammatory state and senses microbial products in blood. J Exp Med (2017) 0.75

Articles cited by this

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 29.42

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med (1998) 19.03

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med (2000) 16.09

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity (2000) 15.44

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med (2000) 13.13

Regulatory T cells: key controllers of immunologic self-tolerance. Cell (2000) 10.19

CTLA-4 can function as a negative regulator of T cell activation. Immunity (1994) 9.80

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol (2002) 9.18

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity (2002) 8.28

CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol (1998) 7.31

Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors. J Immunol (1989) 5.39

Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest (2002) 4.73

Certified professionals: CD4(+)CD25(+) suppressor T cells. J Exp Med (2001) 3.39

Regulation of surface and intracellular expression of CTLA4 on mouse T cells. J Immunol (1996) 2.69

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J Exp Med (1994) 2.33

Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity (2002) 2.20

Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun (2000) 2.14

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc Natl Acad Sci U S A (1990) 2.13

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling. J Exp Med (1997) 1.92

Constitutive synthesis of tumor necrosis factor in the thymus. Proc Natl Acad Sci U S A (1992) 1.89

Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII. Curr Biol (2000) 1.56

A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis. J Immunol (2001) 1.51

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J Exp Med (1996) 1.39

The temporal importance of TNFalpha expression in the development of diabetes. Immunity (2000) 1.27

Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice. Immunol Rev (1999) 1.03

The role of TNF alpha and related cytokines in the development and function of the autoreactive T-cell repertoire. Res Immunol (1997) 1.03

TNF and receptors in organ-specific autoimmune disease: multi-layered functioning mirrored in animal models. J Clin Invest (2001) 1.01

Thymic reticulum of autoimmune mice. II: Ultrastructural studies of mice with lupus-like syndrome (NZB, BXSB, MRL/l). J Autoimmun (1990) 0.89

Thymus reticulum of autoimmune mice. 3. Ultrastructural study of NOD (non-obese diabetic) mouse thymus. Int J Exp Pathol (1991) 0.88

Articles by these authors

An early Ediacaran assemblage of macroscopic and morphologically differentiated eukaryotes. Nature (2011) 1.92

Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS. Intensive Care Med (2014) 1.90

Ten-year results of endovascular abdominal aortic aneurysm repair from a large multicenter registry. J Vasc Surg (2013) 1.83

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A (2008) 1.66

Genetic control of the antibody responses: relationship between immune response and histocompatibility (H-2) type. 1969. J Immunol (2004) 1.38

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes. Proc Natl Acad Sci U S A (2006) 1.17

Multiresolution foveated laparoscope with high resolvability. Opt Lett (2013) 1.11

DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype. Proc Natl Acad Sci U S A (2006) 1.04

The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation. Proc Natl Acad Sci U S A (2005) 0.99

Nodal and lefty signaling regulates the growth of pancreatic cells. Dev Dyn (2008) 0.96

Development of magnesium calcium phosphate biocement for bone regeneration. J R Soc Interface (2010) 0.95

The role of interferon alpha in initiation of type I diabetes in the NOD mouse. Clin Immunol (2011) 0.92

Extended depth-of-field microscopic imaging with a variable focus microscope objective. Opt Express (2011) 0.92

Prescribed intensity design for extended sources in three-dimensional rotational geometry. Opt Lett (2015) 0.92

Glomerular territories in the olfactory bulb from the larval stage of the sea lamprey Petromyzon marinus. J Comp Neurol (2003) 0.90

Design of an optical see-through head-mounted display with a low f-number and large field of view using a freeform prism. Appl Opt (2009) 0.88

Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor. Mol Pharmacol (2011) 0.87

Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells. Proc Natl Acad Sci U S A (2004) 0.87

Phlorofucofuroeckol A inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK. Toxicol In Vitro (2011) 0.87

Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells. Proc Natl Acad Sci U S A (2008) 0.86

Time-multiplexed dual-focal plane head-mounted display with a liquid lens. Opt Lett (2009) 0.85

Multiple oral Candida infections in patients with Sjogren's syndrome -- prevalence and clinical and drug susceptibility profiles. J Rheumatol (2011) 0.85

Potent Antifungal Activity of Pure Compounds from Traditional Chinese Medicine Extracts against Six Oral Candida Species and the Synergy with Fluconazole against Azole-Resistant Candida albicans. Evid Based Complement Alternat Med (2012) 0.84

Imaging properties of extended depth of field microscopy through single-shot focus scanning. Opt Express (2015) 0.84

Diagnostic model of saliva peptide finger print analysis of primary Sjögren's syndrome patients by using weak cation exchange magnetic beads. Biosci Rep (2013) 0.83

Direct design of aspherical lenses for extended non-Lambertian sources in two-dimensional geometry. Opt Lett (2015) 0.83

Effects of total glucosides of paeony for delaying onset of Sjogren's syndrome: an animal study. J Craniomaxillofac Surg (2013) 0.83

A systematic review of acupuncture or acupoint injection for management of burning mouth syndrome. Quintessence Int (2012) 0.83

Repurposing of yunnan baiyao as an alternative therapy for minor recurrent aphthous stomatitis. Evid Based Complement Alternat Med (2012) 0.82

[Clinical assessment of oral diagnostic items in 2002 classification criteria for primary Sjogren's syndrome]. Beijing Da Xue Xue Bao (2012) 0.81

Preliminary investigation of bioactivity of nano biocomposite. J Mater Sci Mater Med (2007) 0.81

A high-resolution optical see-through head-mounted display with eyetracking capability. Opt Express (2013) 0.81

Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene. Autoimmunity (2004) 0.80

New alternative therapy for orofacial localized scleroderma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 0.80

A 3D integral imaging optical see-through head-mounted display. Opt Express (2014) 0.80

A systematic method for designing depth-fused multi-focal plane three-dimensional displays. Opt Express (2010) 0.79

A novel prototype for an optical see-through head-mounted display with addressable focus cues. IEEE Trans Vis Comput Graph (2010) 0.78

Design, tolerance, and fabrication of an optical see-through head-mounted display with free-form surface elements. Appl Opt (2013) 0.78

Oral lichen sclerosus et atrophicus - literature review and two clinical cases. Chin J Dent Res (2013) 0.78

Oral manifestation of chronic mucocutaneous candidiasis: seven case reports. J Oral Pathol Med (2007) 0.77

Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation. Endocrine (2010) 0.77

Paraneoplastic pemphigus characterized by polymorphic oral mucosal manifestations--report of two cases. Quintessence Int (2010) 0.77

Sialoadenitis progression in nonobese diabetic mice and its correlation with expression of apoptosis-associated proteins in salivary glands and serum IgG levels. Chin Med J (Engl) (2007) 0.76

Effects of Multi-glycosides of Tripterygium wilfordiion in the Treatment of Sjögren's Syndrome in the Non-obese Diabetic Mouse Model. Chin J Dent Res (2015) 0.76

Congenital agenesis of all major salivary glands and absence of unilateral lacrimal puncta: a case report and review of the literature. Acta Otolaryngol (2012) 0.76

Role of salivary anti-SSA/B antibodies for diagnosing primary Sjögren's syndrome. Med Oral Patol Oral Cir Bucal (2015) 0.75

Direct design of aspherical lenses for extended non-Lambertian sources in three-dimensional rotational geometry. Opt Express (2016) 0.75

Optical design and system engineering of a multiresolution foveated laparoscope. Appl Opt (2016) 0.75

Efficacy and safety of Chinese patent medicines in the treatment of recurrent aphthous stomatitis: A systematic review. J Am Dent Assoc (2017) 0.75

[Histopathological features of oral pemphigus vegetans]. Zhonghua Kou Qiang Yi Xue Za Zhi (2005) 0.75

Video-based eyetracking methods and algorithms in head-mounted displays. Opt Express (2006) 0.75

Systematic characterization and optimization of 3D light field displays. Opt Express (2017) 0.75

Design and prototype of an augmented reality display with per-pixel mutual occlusion capability. Opt Express (2017) 0.75

Effects of Ganoderma lucidum spores on sialoadenitis of nonobese diabetic mice. Chin Med J (Engl) (2009) 0.75

Magic lenses for augmented virtual environments. IEEE Comput Graph Appl (2006) 0.75

Structured illumination assisted microdeflectometry with optical depth scanning capability. Opt Lett (2016) 0.75

Effects of Configuration of Optical Combiner on Near-Field Depth Perception in Optical See-Through Head-Mounted Displays. IEEE Trans Vis Comput Graph (2016) 0.75

Design of a polarized head-mounted projection display using ferroelectric liquid-crystal-on-silicon microdisplays. Appl Opt (2008) 0.75

Characterizing polarization management in a p-HMPD system. Appl Opt (2008) 0.75

Quantity of Candida Colonies in Saliva: 
A Diagnostic Evaluation for Oral Candidiasis. Chin J Dent Res (2017) 0.75

[Fractionation of soluble COD in wastewater based on batch respirometric method]. Huan Jing Ke Xue (2009) 0.75

Application of flat-sheet membrane to thickening and digestion of waste activated sludge (WAS). J Hazard Mater (2007) 0.75

[Study on total glucosides of peony preventing non-obese diabetic mice from sialoadenitis]. Hua Xi Kou Qiang Yi Xue Za Zhi (2011) 0.75

Design of a wide-angle, lightweight head-mounted display using free-form optics tiling. Opt Lett (2011) 0.75

High dynamic range head mounted display based on dual-layer spatial modulation. Opt Express (2017) 0.75

[Preliminary study of the relationship between tumor like Sjögren's syndrome and malignant lymphoma]. Zhonghua Kou Qiang Yi Xue Za Zhi (2012) 0.75

[Detection of oral fungal flora in patients with primary Sjogren's syndrome by real-time PCR]. Beijing Da Xue Xue Bao (2013) 0.75

High-resolution optical see-through multi-focal-plane head-mounted display using freeform optics. Opt Express (2014) 0.75

Lipoid Proteinosis Resulting from a Large Homozygous Deletion Affecting Part of the ECM1 Gene and Adjacent Long Non-coding RNA. Acta Derm Venereol (2015) 0.75

Augmented reality three-dimensional object visualization and recognition with axially distributed sensing. Opt Lett (2016) 0.75

Automatic image performance balancing in lens optimization. Opt Express (2010) 0.75

Prism-based tri-aperture laparoscopic objective for multi-view acquisition. Opt Express (2022) 0.75

Multiview panoramic cameras using mirror pyramids. IEEE Trans Pattern Anal Mach Intell (2004) 0.75

Design and tolerance of a free-form optical system for an optical see-through multi-focal-plane display. Appl Opt (2015) 0.75

Effects of Optical Combiner and IPD Change for Convergence on Near-Field Depth Perception in an Optical See-Through HMD. IEEE Trans Vis Comput Graph (2016) 0.75

Focus issue introduction: 3D image acquisition and display: technology, perception and applications. Opt Express (2022) 0.75

Effects of Viewing Conditions and Rotation Methods in a Collaborative Tabletop AR Environment. IEEE Trans Vis Comput Graph (2011) 0.75

Imaging quality of a retroreflective screen in head-mounted projection displays. J Opt Soc Am A Opt Image Sci Vis (2009) 0.75

Theoretical analysis for integral imaging performance based on microscanning of a microlens array. Opt Lett (2008) 0.75