Published in Cancer Res on January 01, 2002
Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development (2008) 1.90
Neuroblastoma and MYCN. Cold Spring Harb Perspect Med (2013) 1.75
Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2. Mol Cell Biol (2006) 1.67
Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice. Mol Cell Biol (2005) 1.50
The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential. Pancreas (2015) 1.42
E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells. Mol Cell Biol (2006) 1.31
Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrest. Mol Cell Biol (2006) 1.19
Myocardial smad4 is essential for cardiogenesis in mouse embryos. Circ Res (2007) 1.19
Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions. Dev Biol (2012) 1.11
A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration. EMBO J (2005) 1.09
Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma. Am J Pathol (2006) 1.08
The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system. Proc Natl Acad Sci U S A (2006) 1.06
Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver. Oncogene (2008) 1.01
The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis. Front Oncol (2012) 1.01
The connections between neural crest development and neuroblastoma. Curr Top Dev Biol (2011) 1.01
Conditional deletion of N-Myc disrupts neurosensory and non-sensory development of the ear. Dev Dyn (2011) 0.98
In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells. Cancer Immunol Immunother (2011) 0.96
Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics. Development (2010) 0.91
The intracellular localization of ID2 expression has a predictive value in non small cell lung cancer. PLoS One (2009) 0.90
Id2 is dispensable for Myc-induced epidermal neoplasia. Mol Cell Biol (2004) 0.90
FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells. Nucleic Acids Res (2009) 0.89
High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours. Br J Cancer (2002) 0.86
Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridization. Am J Pathol (2007) 0.85
The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma. Mol Cancer Res (2011) 0.84
Mab21l2 is essential for embryonic heart and liver development. PLoS One (2012) 0.83
The bHLH factors extramacrochaetae and daughterless control cell cycle in Drosophila imaginal discs through the transcriptional regulation of the Cdc25 phosphatase string. PLoS Genet (2014) 0.82
Mutational ataxia resulting from abnormal vestibular acquisition and processing is partially compensated for. Behav Neurosci (2012) 0.81
Overexpression of inhibitor of DNA-binding 2 attenuates pulmonary fibrosis through regulation of c-Abl and Twist. Am J Pathol (2015) 0.80
A mechanism linking Id2-TGFβ crosstalk to reversible adaptive plasticity in neuroblastoma. PLoS One (2013) 0.80
The Id-protein family in developmental and cancer-associated pathways. Cell Commun Signal (2017) 0.78
The Wnt/β-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cells. Sci Rep (2016) 0.77
Myocardial Mycn is essential for mouse ventricular wall morphogenesis. Dev Biol (2012) 0.77
ID2 and ID3 protein expression mirrors granulopoietic maturation and discriminates between acute leukemia subtypes. Histochem Cell Biol (2013) 0.76
Induction of IL21 in Peripheral T Follicular Helper Cells Is an Indicator of Influenza Vaccine Response in a Previously Vaccinated HIV-Infected Pediatric Cohort. J Immunol (2017) 0.75
Id2 regulates the proliferation of squamous cell carcinoma in vitro via the NF-κB/Cyclin D1 pathway. Chin J Cancer (2012) 0.75
Id2a is required for hepatic outgrowth during liver development in zebrafish. Mech Dev (2015) 0.75
The Role of Id2 Protein in Neuroblatoma in Children. Pathol Oncol Res (2015) 0.75
Combination of Id2 Knockdown Whole Tumor Cells and Checkpoint Blockade: A Potent Vaccine Strategy in a Mouse Neuroblastoma Model. PLoS One (2015) 0.75
The MYCN Protein in Health and Disease. Genes (Basel) (2017) 0.75
siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells. Oncol Lett (2017) 0.75
The transcriptional network for mesenchymal transformation of brain tumours. Nature (2009) 8.44
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat Immunol (2008) 5.10
Transforming fusions of FGFR and TACC genes in human glioblastoma. Science (2012) 5.09
Id family of helix-loop-helix proteins in cancer. Nat Rev Cancer (2005) 3.80
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoS One (2008) 3.68
Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J Exp Med (2007) 3.36
Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature (2006) 3.31
Transcriptional profiling identifies Id2 function in dendritic cell development. Nat Immunol (2003) 2.91
The integrated landscape of driver genomic alterations in glioblastoma. Nat Genet (2013) 2.89
Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc Natl Acad Sci U S A (2004) 2.75
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity (2008) 2.57
Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma. Cancer Cell (2012) 2.50
Transcription-coupled events associating with immunoglobulin switch region chromatin. Science (2003) 2.50
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature (2008) 2.46
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol (2008) 2.32
The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. Immunity (2012) 2.15
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell (2007) 2.12
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell (2009) 2.04
Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas. Cancer Res (2006) 2.03
The balance between Pax5 and Id2 activities is the key to AID gene expression. J Exp Med (2003) 1.96
Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol (2012) 1.89
Essential role of Id2 in negative regulation of IgE class switching. Nat Immunol (2002) 1.71
Initiation of NALT organogenesis is independent of the IL-7R, LTbetaR, and NIK signaling pathways but requires the Id2 gene and CD3(-)CD4(+)CD45(+) cells. Immunity (2002) 1.70
Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2. Mol Cell Biol (2006) 1.67
Towards patient-based cancer therapeutics. Nat Biotechnol (2010) 1.63
Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid. J Clin Invest (2006) 1.57
Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell (2007) 1.56
Local lymph node involvement in pediatric renal cell carcinoma: a report from the Italian TREP project. Pediatr Blood Cancer (2008) 1.52
MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. FASEB J (2009) 1.51
Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma. Cell Cycle (2009) 1.50
Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice. Mol Cell Biol (2005) 1.50
Effects of botulinum toxin type a in the bladder wall of children with neurogenic bladder dysfunction: a comparison of histological features before and after injections. J Urol (2011) 1.50
Disseminated neuroblastoma in children older than one year at diagnosis: comparable results with three consecutive high-dose protocols adopted by the Italian Co-Operative Group for Neuroblastoma. J Clin Oncol (2003) 1.47
Feasibility and diagnostic agreement in teledermatopathology using a virtual slide system. Hum Pathol (2007) 1.39
Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation. Blood (2005) 1.38
RAS signaling dysregulation in human embryonal Rhabdomyosarcoma. Genes Chromosomes Cancer (2009) 1.36
Two distinct types of Langerhans cells populate the skin during steady state and inflammation. Immunity (2012) 1.36
E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells. Mol Cell Biol (2006) 1.31
Impaired IgG production in mice deficient for heat shock transcription factor 1. J Biol Chem (2004) 1.29
Id2 drives differentiation and suppresses tumor formation in the intestinal epithelium. Cancer Res (2004) 1.26
E protein transcription factors are required for the development of CD4(+) lineage T cells. Immunity (2012) 1.25
Id2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteins. Blood (2008) 1.24
Malignant pancreatic endocrine tumor in a child with tuberous sclerosis. Am J Surg Pathol (2003) 1.21
Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models. Clin Cancer Res (2008) 1.18
Outcomes and prognostic factors after recurrence in children and adolescents with nonmetastatic rhabdomyosarcoma. Cancer (2005) 1.16
The use of muscle biopsy in the diagnosis of undefined ataxia with cerebellar atrophy in children. Eur J Paediatr Neurol (2011) 1.09
Genotype-phenotype relationship in human ATP6i-dependent autosomal recessive osteopetrosis. Am J Pathol (2003) 1.09
Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F. Cancer Res (2010) 1.09
Unexplained neonatal respiratory distress due to congenital surfactant deficiency. J Pediatr (2007) 1.09
TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice. J Allergy Clin Immunol (2003) 1.09
The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system. Proc Natl Acad Sci U S A (2006) 1.06
Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation. Neuromuscul Disord (2006) 1.06
Chemotherapy and surgery in children with cystic echinococcosis. Pediatr Infect Dis J (2010) 1.05
Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity. J Exp Med (2009) 1.04
Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation. J Cell Physiol (2006) 1.04
Inflammatory myofibroblastic tumors in childhood: a report from the Italian Cooperative Group studies. Cancer (2010) 1.04
Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo. Clin Cancer Res (2006) 1.04
Impact of a single nucleotide polymorphism in the MDM2 gene on neuroblastoma development and aggressiveness: results of a pilot study on 239 patients. Clin Cancer Res (2008) 1.03
Genetic and biochemical properties of streptococcal NAD-glycohydrolase inhibitor. J Biol Chem (2005) 1.03
Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells. Development (2005) 1.03
Nucleo-cytoplasmic shuttling of Id2, a negative regulator of basic helix-loop-helix transcription factors. J Biol Chem (2004) 1.03
Preserved antibody levels and loss of memory B cells against pneumococcus and tetanus after splenectomy: tailoring better vaccination strategies. Eur J Immunol (2013) 1.02
Mature and immature teratomas: results of the first paediatric Italian study. Pediatr Surg Int (2007) 1.02
Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum. Proc Natl Acad Sci U S A (2010) 1.01
Identification of BMP-responsive elements in the mouse Id2 gene. Biochem Biophys Res Commun (2010) 0.99
Synergistic post-transcriptional regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 specific binding. PLoS One (2011) 0.99
Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. J Clin Invest (2012) 0.98
Molecular characterization of NADase-streptolysin O operon of hemolytic streptococci. Biochim Biophys Acta (2004) 0.98
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes Dev (2014) 0.98
Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells. Kidney Int (2005) 0.96
Bladder augmentation using acellular collagen biomatrix: a pilot experience in exstrophic patients. Pediatr Surg Int (2012) 0.96
Elevated levels of miR-145 correlate with SMAD3 down-regulation in cystic fibrosis patients. J Cyst Fibros (2013) 0.96
IL-21 induces inhibitor of differentiation 2 and leads to complete abrogation of anaphylaxis in mice. J Immunol (2007) 0.96
Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. Int J Cancer (2009) 0.95
Regulation of Id2 expression by CCAAT/enhancer binding protein beta. Nucleic Acids Res (2005) 0.95
Role of Id proteins in B lymphocyte activation: new insights from knockout mouse studies. J Mol Med (Berl) (2004) 0.94
Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development. J Immunol (2013) 0.94
c-Kit is preferentially expressed in MYCN-amplified neuroblastoma and its effect on cell proliferation is inhibited in vitro by STI-571. Int J Cancer (2003) 0.94
Cystic dysplasia of the rete testis: report of two cases and review of the literature. Pediatr Dev Pathol (2002) 0.93
NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells. Cancer Res (2010) 0.93
Expression of the lipogenic enzyme fatty acid synthase (FAS) in retinoblastoma and its correlation with tumor aggressiveness. Invest Ophthalmol Vis Sci (2003) 0.93
RHPN2 drives mesenchymal transformation in malignant glioma by triggering RhoA activation. Cancer Res (2013) 0.92
A child with painful legs. Lancet (2005) 0.92
Clinical significance of CXC chemokine receptor-4 and c-Met in childhood rhabdomyosarcoma. Clin Cancer Res (2008) 0.92
Nephroblastoma: multidrug-resistance P-glycoprotein expression in tumor cells and intratumoral capillary endothelial cells. Am J Clin Pathol (2002) 0.91
Recurrent metanephric stromal tumor in an infant. Urology (2011) 0.91