Published in Mol Cell on January 01, 2002
A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin. J Cell Biol (2005) 2.27
The moving parts of the nucleolus. Histochem Cell Biol (2005) 1.81
Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies. J Cell Biol (2003) 1.61
Improved proteome coverage by using high efficiency cysteinyl peptide enrichment: the human mammary epithelial cell proteome. Proteomics (2005) 1.33
Cancer biomarker discovery: the entropic hallmark. PLoS One (2010) 1.26
The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA. Mol Biol Cell (2005) 1.25
Going in GTP cycles in the nucleolus. J Cell Biol (2005) 1.06
Quantitative organelle proteomics of MCF-7 breast cancer cells reveals multiple subcellular locations for proteins in cellular functional processes. J Proteome Res (2010) 0.96
CTD kinase I is involved in RNA polymerase I transcription. Nucleic Acids Res (2004) 0.91
Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin. Proc Natl Acad Sci U S A (2008) 0.89
A cell cycle role for the epigenetic factor CTCF-L/BORIS. PLoS One (2012) 0.87
The nucleus introduced. Cold Spring Harb Perspect Biol (2011) 0.78
Proteomic analysis of bovine nucleolus. Genomics Proteomics Bioinformatics (2010) 0.75
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature (2002) 19.77
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature (2011) 10.77
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell (2006) 8.53
Regulation of alternative splicing by histone modifications. Science (2010) 7.98
Lamin A-dependent nuclear defects in human aging. Science (2006) 6.71
Global transcription in pluripotent embryonic stem cells. Cell Stem Cell (2008) 5.81
Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell (2007) 5.62
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc Natl Acad Sci U S A (2003) 5.59
Chromatin in pluripotent embryonic stem cells and differentiation. Nat Rev Mol Cell Biol (2006) 5.18
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med (2005) 5.01
Epigenetics in alternative pre-mRNA splicing. Cell (2011) 4.74
Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science (2003) 4.74
A kinetic framework for a mammalian RNA polymerase in vivo. Science (2002) 4.42
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol (2004) 4.41
Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol (2007) 4.35
Transcription dynamics. Mol Cell (2009) 4.15
Spatial proximity of translocation-prone gene loci in human lymphomas. Nat Genet (2003) 3.91
Activation of the cellular DNA damage response in the absence of DNA lesions. Science (2008) 3.17
Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol (2004) 3.02
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol (2008) 2.93
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression. Proc Natl Acad Sci U S A (2008) 2.58
Tissue-specific spatial organization of genomes. Genome Biol (2004) 2.57
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2006) 2.53
Cell biology: chromosome territories. Nature (2007) 2.47
Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol (2009) 2.40
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J Cell Sci (2006) 2.37
Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol Cell Biol (2004) 2.33
Chromosome positioning in the interphase nucleus. Trends Cell Biol (2002) 2.32
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature (2007) 2.30
The meaning of gene positioning. Cell (2008) 2.16
Functional implications of genome topology. Nat Struct Mol Biol (2013) 2.13
Spatial genome organization in the formation of chromosomal translocations. Semin Cancer Biol (2006) 2.12
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication. Nat Med (2004) 1.97
Spatial dynamics of chromosome translocations in living cells. Science (2013) 1.95
Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo. Nat Struct Mol Biol (2006) 1.94
In vivo kinetics of Cajal body components. J Cell Biol (2004) 1.91
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
The lamin protein family. Genome Biol (2011) 1.85
Functional association of Sun1 with nuclear pore complexes. J Cell Biol (2007) 1.81
Human chromokinesin KIF4A functions in chromosome condensation and segregation. J Cell Biol (2004) 1.81
Competition between histone H1 and HMGN proteins for chromatin binding sites. EMBO Rep (2002) 1.74
Biogenesis of nuclear bodies. Cold Spring Harb Perspect Biol (2010) 1.69
Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP. Genes Dev (2008) 1.62
In vitro generation of human cells with cancer stem cell properties. Nat Cell Biol (2011) 1.61
Quantitation of GFP-fusion proteins in single living cells. J Struct Biol (2002) 1.59
Conservation of relative chromosome positioning in normal and cancer cells. Curr Biol (2002) 1.58
Locus-specific and activity-independent gene repositioning during early tumorigenesis. J Cell Biol (2008) 1.56
The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol (2006) 1.52
A cyclophilin functions in pre-mRNA splicing. EMBO J (2002) 1.49
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem (2002) 1.45
Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma. Proc Natl Acad Sci U S A (2009) 1.44
Chromokinesins: multitalented players in mitosis. Trends Cell Biol (2005) 1.41
Spatial genome organization. Exp Cell Res (2004) 1.39
LINC complexes in health and disease. Nucleus (2011) 1.37
Mobility and immobility of chromatin in transcription and genome stability. Curr Opin Genet Dev (2007) 1.37
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. J Cell Biol (2009) 1.36
Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs. Mol Cell (2002) 1.30
In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin. Mol Cell Biol (2004) 1.26
Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol (2006) 1.25
An uncertainty principle in chromosome positioning. Trends Cell Biol (2003) 1.19
Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins. Nucleus (2011) 1.19
More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation. Curr Opin Genet Dev (2011) 1.18
Eliminating the impact of the Impact Factor. J Cell Biol (2013) 1.15
Identification of differential protein interactors of lamin A and progerin. Nucleus (2010) 1.14
Disease-specific gene repositioning in breast cancer. J Cell Biol (2009) 1.13
Recruitment of dioxin receptor to active transcription sites. Mol Biol Cell (2002) 1.08
The central role of chromatin maintenance in aging. Aging (Albany NY) (2009) 1.07
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk). Bioorg Med Chem Lett (2009) 1.06
Differential in vivo binding dynamics of somatic and oocyte-specific linker histones in oocytes and during ES cell nuclear transfer. Mol Biol Cell (2005) 1.05
A non-random walk through the genome. Genome Biol (2005) 1.04
Systems biology in the cell nucleus. J Cell Sci (2005) 1.04
Measuring dynamics of nuclear proteins by photobleaching. Curr Protoc Cell Biol (2003) 1.01
Mapping of lamin A- and progerin-interacting genome regions. Chromosoma (2012) 1.01
New tools for JCB. J Cell Biol (2011) 1.01
SnapShot: Chromosome confirmation capture. Cell (2012) 1.00
Friends, colleagues, authors, lend us your data. J Cell Biol (2010) 1.00
Genome instability in progeria: when repair gets old. Nat Med (2005) 0.99
The JCB DataViewer scales up. J Cell Biol (2012) 0.98
Tumor formation via loss of a molecular motor protein. Curr Biol (2006) 0.97
Non-coding RNAs in DNA damage and repair. FEBS Lett (2013) 0.97
Chinese hamster ORC subunits dynamically associate with chromatin throughout the cell-cycle. Exp Cell Res (2005) 0.95
The cell nucleus and aging: tantalizing clues and hopeful promises. PLoS Biol (2005) 0.95
Cell biology: Nuclear order out of chaos. Nature (2008) 0.93
On the contribution of spatial genome organization to cancerous chromosome translocations. J Natl Cancer Inst Monogr (2008) 0.92
Automatic segmentation and supervised learning-based selection of nuclei in cancer tissue images. Cytometry A (2012) 0.91
Genomes, proteomes, and dynamic networks in the cell nucleus. Histochem Cell Biol (2002) 0.91
Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo. PLoS Biol (2005) 0.90
A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines. Oncotarget (2013) 0.89
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). Bioorg Med Chem Lett (2011) 0.89
DNA damage, chromatin, and transcription: the trinity of aging. Curr Opin Cell Biol (2012) 0.88
H1FOO is coupled to the initiation of oocytic growth. Biol Reprod (2004) 0.88
Automatic nuclei segmentation and spatial FISH analysis for cancer detection. Conf Proc IEEE Eng Med Biol Soc (2009) 0.88
Splicing misplaced. Cell (2005) 0.88
Ranked retrieval of segmented nuclei for objective assessment of cancer gene repositioning. BMC Bioinformatics (2012) 0.87
Systematic identification of pathological lamin A interactors. Mol Biol Cell (2014) 0.86
Formation of nuclear splicing factor compartments is independent of lamins A/C. Mol Biol Cell (2004) 0.86
Good news in the nuclear envelope: loss of lamin A might be a gain. J Clin Invest (2006) 0.86
Chromatin maintenance by a molecular motor protein. Nucleus (2011) 0.86
Mapping of protein- and chromatin-interactions at the nuclear lamina. Nucleus (2010) 0.84