Published in Trends Cell Biol on September 01, 2002
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol (2005) 4.33
Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2006) 3.16
Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J Cell Biol (2003) 2.85
Macrodomain organization of the Escherichia coli chromosome. EMBO J (2004) 2.62
Tissue-specific spatial organization of genomes. Genome Biol (2004) 2.57
Molecular dissection of formation of senescence-associated heterochromatin foci. Mol Cell Biol (2007) 2.56
The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences. Proc Natl Acad Sci U S A (2006) 2.44
Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes Dev (2008) 2.17
Spatial genome organization in the formation of chromosomal translocations. Semin Cancer Biol (2006) 2.12
Coregulated human globin genes are frequently in spatial proximity when active. J Cell Biol (2006) 2.12
Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev (2003) 2.07
Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells. J Cell Biol (2004) 1.98
Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res (2003) 1.94
The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv Immunol (2010) 1.77
Chromosome territory arrangement and homologous pairing in nuclei of Arabidopsis thaliana are predominantly random except for NOR-bearing chromosomes. Chromosoma (2004) 1.62
Nuclear functions of actin. Cold Spring Harb Perspect Biol (2010) 1.55
Chromosome arm length and nuclear constraints determine the dynamic relationship of yeast subtelomeres. Proc Natl Acad Sci U S A (2010) 1.50
The 4q subtelomere harboring the FSHD locus is specifically anchored with peripheral heterochromatin unlike most human telomeres. J Cell Biol (2004) 1.48
Principles of chromosomal organization: lessons from yeast. J Cell Biol (2011) 1.47
The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture. Chromosoma (2005) 1.45
c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus. Proc Natl Acad Sci U S A (2005) 1.43
Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts. Genome Biol (2010) 1.38
Radial arrangement of chromosome territories in human cell nuclei: a computer model approach based on gene density indicates a probabilistic global positioning code. Biophys J (2004) 1.35
The role of CTCF in regulating nuclear organization. J Exp Med (2008) 1.30
The three-dimensional organization of telomeres in the nucleus of mammalian cells. BMC Biol (2004) 1.29
Gene positioning. Cold Spring Harb Perspect Biol (2010) 1.12
Differences in centromere positioning of cycling and postmitotic human cell types. Chromosoma (2004) 1.12
Chromosome territories have a highly nonspherical morphology and nonrandom positioning. Chromosome Res (2007) 1.04
A non-random walk through the genome. Genome Biol (2005) 1.04
Sequence signature analysis of chromosome identity in three Drosophila species. BMC Bioinformatics (2005) 1.04
Long-range interphase chromosome organization in Drosophila: a study using color barcoded fluorescence in situ hybridization and structural clustering analysis. Mol Biol Cell (2004) 1.03
Non-random positioning of chromosomes in human sperm nuclei. Chromosome Res (2004) 1.03
Recovering ensembles of chromatin conformations from contact probabilities. Nucleic Acids Res (2012) 1.02
The manipulation of chromosomes by mankind: the uses of microcell-mediated chromosome transfer. Chromosoma (2005) 1.02
The changes in chromosome 6 spatial organization during chromatin polytenization in the Calliphora erythrocephala Mg. (Diptera: Calliphoridae) nurse cells. Protoplasma (2012) 0.98
Dynamics of relative chromosome position during the cell cycle. Mol Biol Cell (2004) 0.97
Positioning of NORs and NOR-bearing chromosomes in relation to nucleoli. J Struct Biol (2007) 0.97
Nuclear position dictates DNA repair pathway choice. Genes Dev (2014) 0.96
Compartmentalization of the yeast meiotic nucleus revealed by analysis of ectopic recombination. Genetics (2004) 0.96
Epigenomic differentiation in mouse preimplantation nuclei of biparental, parthenote and cloned embryos. Chromosome Res (2007) 0.96
Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells. Chromosome Res (2007) 0.94
Nuclear location of a chromatin insulator in Drosophila melanogaster. J Cell Sci (2004) 0.94
Chromatin position in human HepG2 cells: although being non-random, significantly changed in daughter cells. J Struct Biol (2008) 0.93
Chromosome positioning from activity-based segregation. Nucleic Acids Res (2014) 0.90
Chromosome conformation of human fibroblasts grown in 3-dimensional spheroids. Nucleus (2015) 0.90
Gene expression, chromosome position and lamin A/C mutations. Nucleus (2011) 0.90
Heterochromatic self-association, a determinant of nuclear organization, does not require sequence homology in Drosophila. Genetics (2003) 0.89
Human archival tissues provide a valuable source for the analysis of spatial genome organization. Histochem Cell Biol (2005) 0.89
ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells. PLoS One (2014) 0.89
Inheriting nuclear organization: can nuclear lamins impart spatial memory during post-mitotic nuclear assembly? Chromosome Res (2010) 0.89
Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues. BMC Cell Biol (2012) 0.89
Ranked retrieval of segmented nuclei for objective assessment of cancer gene repositioning. BMC Bioinformatics (2012) 0.87
POF regulates the expression of genes on the fourth chromosome in Drosophila melanogaster by binding to nascent RNA. Mol Cell Biol (2012) 0.86
Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells. Genes Chromosomes Cancer (2009) 0.86
Gene clusters, molecular evolution and disease: a speculation. Curr Genomics (2009) 0.85
Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited. BMC Cancer (2006) 0.85
Experimental techniques for study of chromatin mechanics in intact nuclei and living cells. Chromosome Res (2008) 0.85
Chromosome territory positioning of conserved homologous chromosomes in different primate species. Chromosoma (2006) 0.85
Twenty-four chromosome FISH in human IVF embryos reveals patterns of post-zygotic chromosome segregation and nuclear organisation. Chromosome Res (2012) 0.84
Chromosome territories, X;Y translocation and Premature Ovarian Failure: is there a relationship? Mol Cytogenet (2009) 0.84
Chromatin physics: Replacing multiple, representation-centered descriptions at discrete scales by a continuous, function-dependent self-scaled model. Eur Phys J E Soft Matter (2006) 0.82
Positioning of the NOR-bearing chromosomes in relation to nucleoli in daughter cells after mitosis. Physiol Res (2008) 0.82
Nuclear organisation of sperm remains remarkably unaffected in the presence of defective spermatogenesis. Chromosome Res (2011) 0.82
Hierarchical radial and polar organisation of chromosomes in human sperm. Chromosome Res (2012) 0.82
3D organization of telomeres in porcine neutrophils and analysis of LPS-activation effect. BMC Cell Biol (2013) 0.82
Transcriptomic and nuclear architecture of immune cells after LPS activation. Chromosoma (2011) 0.81
Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes. Nucleic Acids Res (2013) 0.81
Hierarchies in eukaryotic genome organization: Insights from polymer theory and simulations. BMC Biophys (2011) 0.80
Methylation of the nonhomologous end joining repair pathway genes does not explain the increase of translocations with aging. Age (Dordr) (2014) 0.80
Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA. Mol Cytogenet (2009) 0.80
Imaging genome abnormalities in cancer research. Cell Chromosome (2004) 0.80
Spatial organization of genes as a component of regulated expression. Chromosoma (2009) 0.80
Integrating nuclear receptor mobility in models of gene regulation. Nucl Recept Signal (2006) 0.79
Interspecific chromosome-wide transcription profiles reveal the existence of mammalian-specific and species-specific chromosome domains. J Mol Evol (2004) 0.79
Chromosome loops arising from intrachromosomal tethering of telomeres occur at high frequency in G1 (non-cycling) mitotic cells: Implications for telomere capture. Cell Chromosome (2004) 0.79
An architectural genetic and epigenetic perspective. Integr Biol (Camb) (2010) 0.78
3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression. Nat Commun (2016) 0.78
IMACULAT - an open access package for the quantitative analysis of chromosome localization in the nucleus. PLoS One (2013) 0.78
Nuclear positioning, higher-order folding, and gene expression of Mmu15 sequences are refractory to chromosomal translocation. Chromosoma (2010) 0.78
Cell-type specific proximity of centromeric domains of one homologue each of chromosomes 2 and 11 in nuclei of cerebellar Purkinje neurons. Chromosoma (2006) 0.78
Comparative analysis of individual chromosome involvement in micronuclei induced by mitomycin C and bleomycin in human leukocytes. Mol Cytogenet (2016) 0.78
Localization of chromosome regions in potoroo nuclei ( Potorous tridactylus Marsupialia: Potoroinae). Chromosoma (2003) 0.78
A 'selfish' B chromosome induces genome elimination by disrupting the histone code in the jewel wasp Nasonia vitripennis. Sci Rep (2017) 0.77
Genome organization, instabilities, stem cells, and cancer. J Stem Cells Regen Med (2009) 0.77
Spatial distribution of centromeres and telomeres at interphase varies among Brachypodium species. J Exp Bot (2015) 0.76
Inferential Structure Determination of Chromosomes from Single-Cell Hi-C Data. PLoS Comput Biol (2016) 0.76
Spatial association of homologous pericentric regions in human lymphocyte nuclei during repair. Biophys J (2004) 0.76
Time-lapse dynamics of the mouse oocyte chromatin organisation during meiotic resumption. Biomed Res Int (2014) 0.76
Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells. Genet Res Int (2011) 0.75
Chromosome territory relocation during DNA repair requires nuclear myosin 1 recruitment to chromatin mediated by ϒ-H2AX signaling. Nucleic Acids Res (2016) 0.75
Chromosomes in a genome-wise order: evidence for metaphase architecture. Mol Cytogenet (2016) 0.75
3D genome structure modeling by Lorentzian objective function. Nucleic Acids Res (2017) 0.75
A sequence-specific interaction between the Saccharomyces cerevisiae rRNA gene repeats and a locus encoding an RNA polymerase I subunit affects ribosomal DNA stability. Mol Cell Biol (2014) 0.75
Unstable chromosome aberrations do not accumulate in normal human fibroblast after fractionated x-irradiation. PLoS One (2015) 0.75
Aneuploidy in spermatids of Robertsonian (Rb) chromosome heterozygous mice. Chromosome Res (2014) 0.75
A method for simultaneously delineating multiple targets in 3D-FISH using limited channels, lasers, and fluorochromes. Eur Biophys J (2013) 0.75
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature (2002) 19.77
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature (2011) 10.77
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell (2006) 8.53
Regulation of alternative splicing by histone modifications. Science (2010) 7.98
Lamin A-dependent nuclear defects in human aging. Science (2006) 6.71
Global transcription in pluripotent embryonic stem cells. Cell Stem Cell (2008) 5.81
Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell (2007) 5.62
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc Natl Acad Sci U S A (2003) 5.59
Chromatin in pluripotent embryonic stem cells and differentiation. Nat Rev Mol Cell Biol (2006) 5.18
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med (2005) 5.01
Epigenetics in alternative pre-mRNA splicing. Cell (2011) 4.74
Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science (2003) 4.74
A kinetic framework for a mammalian RNA polymerase in vivo. Science (2002) 4.42
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol (2004) 4.41
Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol (2007) 4.35
Transcription dynamics. Mol Cell (2009) 4.15
Spatial proximity of translocation-prone gene loci in human lymphomas. Nat Genet (2003) 3.91
Activation of the cellular DNA damage response in the absence of DNA lesions. Science (2008) 3.17
Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol (2004) 3.02
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol (2008) 2.93
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression. Proc Natl Acad Sci U S A (2008) 2.58
Tissue-specific spatial organization of genomes. Genome Biol (2004) 2.57
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2006) 2.53
Cell biology: chromosome territories. Nature (2007) 2.47
Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol (2009) 2.40
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J Cell Sci (2006) 2.37
Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol Cell Biol (2004) 2.33
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature (2007) 2.30
The meaning of gene positioning. Cell (2008) 2.16
Functional implications of genome topology. Nat Struct Mol Biol (2013) 2.13
Spatial genome organization in the formation of chromosomal translocations. Semin Cancer Biol (2006) 2.12
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication. Nat Med (2004) 1.97
Spatial dynamics of chromosome translocations in living cells. Science (2013) 1.95
Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo. Nat Struct Mol Biol (2006) 1.94
In vivo kinetics of Cajal body components. J Cell Biol (2004) 1.91
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
The lamin protein family. Genome Biol (2011) 1.85
Functional association of Sun1 with nuclear pore complexes. J Cell Biol (2007) 1.81
Human chromokinesin KIF4A functions in chromosome condensation and segregation. J Cell Biol (2004) 1.81
Competition between histone H1 and HMGN proteins for chromatin binding sites. EMBO Rep (2002) 1.74
Biogenesis of nuclear bodies. Cold Spring Harb Perspect Biol (2010) 1.69
Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP. Genes Dev (2008) 1.62
In vitro generation of human cells with cancer stem cell properties. Nat Cell Biol (2011) 1.61
Quantitation of GFP-fusion proteins in single living cells. J Struct Biol (2002) 1.59
Conservation of relative chromosome positioning in normal and cancer cells. Curr Biol (2002) 1.58
Locus-specific and activity-independent gene repositioning during early tumorigenesis. J Cell Biol (2008) 1.56
The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol (2006) 1.52
A cyclophilin functions in pre-mRNA splicing. EMBO J (2002) 1.49
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem (2002) 1.45
Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma. Proc Natl Acad Sci U S A (2009) 1.44
Chromokinesins: multitalented players in mitosis. Trends Cell Biol (2005) 1.41
Spatial genome organization. Exp Cell Res (2004) 1.39
LINC complexes in health and disease. Nucleus (2011) 1.37
Mobility and immobility of chromatin in transcription and genome stability. Curr Opin Genet Dev (2007) 1.37
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. J Cell Biol (2009) 1.36
Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs. Mol Cell (2002) 1.30
In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin. Mol Cell Biol (2004) 1.26
Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol (2006) 1.25
An uncertainty principle in chromosome positioning. Trends Cell Biol (2003) 1.19
Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins. Nucleus (2011) 1.19
More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation. Curr Opin Genet Dev (2011) 1.18
Eliminating the impact of the Impact Factor. J Cell Biol (2013) 1.15
Identification of differential protein interactors of lamin A and progerin. Nucleus (2010) 1.14
Disease-specific gene repositioning in breast cancer. J Cell Biol (2009) 1.13
Nucleolomics: an inventory of the nucleolus. Mol Cell (2002) 1.10
Recruitment of dioxin receptor to active transcription sites. Mol Biol Cell (2002) 1.08
The central role of chromatin maintenance in aging. Aging (Albany NY) (2009) 1.07
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk). Bioorg Med Chem Lett (2009) 1.06
Differential in vivo binding dynamics of somatic and oocyte-specific linker histones in oocytes and during ES cell nuclear transfer. Mol Biol Cell (2005) 1.05
Systems biology in the cell nucleus. J Cell Sci (2005) 1.04
A non-random walk through the genome. Genome Biol (2005) 1.04
Measuring dynamics of nuclear proteins by photobleaching. Curr Protoc Cell Biol (2003) 1.01
Mapping of lamin A- and progerin-interacting genome regions. Chromosoma (2012) 1.01
New tools for JCB. J Cell Biol (2011) 1.01
SnapShot: Chromosome confirmation capture. Cell (2012) 1.00
Friends, colleagues, authors, lend us your data. J Cell Biol (2010) 1.00
Genome instability in progeria: when repair gets old. Nat Med (2005) 0.99
The JCB DataViewer scales up. J Cell Biol (2012) 0.98
Tumor formation via loss of a molecular motor protein. Curr Biol (2006) 0.97
Non-coding RNAs in DNA damage and repair. FEBS Lett (2013) 0.97
Chinese hamster ORC subunits dynamically associate with chromatin throughout the cell-cycle. Exp Cell Res (2005) 0.95
The cell nucleus and aging: tantalizing clues and hopeful promises. PLoS Biol (2005) 0.95
Cell biology: Nuclear order out of chaos. Nature (2008) 0.93
On the contribution of spatial genome organization to cancerous chromosome translocations. J Natl Cancer Inst Monogr (2008) 0.92
Automatic segmentation and supervised learning-based selection of nuclei in cancer tissue images. Cytometry A (2012) 0.91
Genomes, proteomes, and dynamic networks in the cell nucleus. Histochem Cell Biol (2002) 0.91
Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo. PLoS Biol (2005) 0.90
A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines. Oncotarget (2013) 0.89
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). Bioorg Med Chem Lett (2011) 0.89
DNA damage, chromatin, and transcription: the trinity of aging. Curr Opin Cell Biol (2012) 0.88
H1FOO is coupled to the initiation of oocytic growth. Biol Reprod (2004) 0.88
Automatic nuclei segmentation and spatial FISH analysis for cancer detection. Conf Proc IEEE Eng Med Biol Soc (2009) 0.88
Splicing misplaced. Cell (2005) 0.88
Ranked retrieval of segmented nuclei for objective assessment of cancer gene repositioning. BMC Bioinformatics (2012) 0.87
Systematic identification of pathological lamin A interactors. Mol Biol Cell (2014) 0.86
Formation of nuclear splicing factor compartments is independent of lamins A/C. Mol Biol Cell (2004) 0.86
Good news in the nuclear envelope: loss of lamin A might be a gain. J Clin Invest (2006) 0.86
Chromatin maintenance by a molecular motor protein. Nucleus (2011) 0.86
Mapping of protein- and chromatin-interactions at the nuclear lamina. Nucleus (2010) 0.84