Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 3938173)

Published in Toxicol Appl Pharmacol on February 15, 2005

Authors

Ofer Spiegelstein1, Amy Gould, Bogdan Wlodarczyk, Marlene Tsie, Xiufen Lu, Chris Le, Aron Troen, Jacob Selhub, Jorge A Piedrahita, J Michael Salbaum, Claudia Kappen, Stepan Melnyk, Jill James, Richard H Finnell

Author Affiliations

1: Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, TX 77030, USA.

Articles cited by this

Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med (1992) 14.22

Cancer risks from arsenic in drinking water. Environ Health Perspect (1992) 6.98

Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. N Engl J Med (1999) 6.27

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci U S A (1992) 5.75

APPEARANCE OF SKELETAL ABNORMALITIES IN THE OFFSPRING OF RATS REARED ON A DEFICIENT DIET. Science (1940) 5.57

Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally. Lancet (1995) 3.48

Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications. Cancer (1994) 2.58

Periconceptional vitamin use, dietary folate, and the occurrence of neural tube defects. Epidemiology (1995) 2.48

The biological chemistry of folate receptors. Blood (1992) 2.27

Cotransformation and gene targeting in mouse embryonic stem cells. Mol Cell Biol (1991) 1.84

Effects of low dietary intake of methionine, choline or proteins on the biotransformation of arsenite in the rabbit. Toxicol Lett (1987) 1.83

Folate receptors. Annu Rev Nutr (1996) 1.82

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet (1999) 1.82

Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida. Am J Epidemiol (1998) 1.80

Genetic polymorphism in the biotransformation of inorganic arsenic and its role in toxicity. Toxicol Lett (2000) 1.74

Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations. Clin Chem (2000) 1.70

Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring. Am J Med Genet (1995) 1.67

Speciation of key arsenic metabolic intermediates in human urine. Anal Chem (2000) 1.65

An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions. Genet Med (2004) 1.57

Carrier-mediated membrane transport of folates in mammalian cells. Annu Rev Nutr (1999) 1.53

Production of multiple congenital abnormalities in young by maternal pteroylglutamic acid deficiency during gestation. J Nutr (1952) 1.43

Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells. J Biol Chem (1989) 1.40

Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis. Biochim Biophys Acta (2001) 1.29

Developmental and reproductive toxicity of inorganic arsenic: animal studies and human concerns. J Toxicol Environ Health B Crit Rev (1998) 1.13

The folate-binding protein of rat kidney. Purification, properties, and cellular distribution. J Biol Chem (1984) 1.13

Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn (2004) 1.10

Role of arsenic as a reproductive toxin with particular attention to neural tube defects. J Toxicol Environ Health (1996) 1.04

Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicol Appl Pharmacol (2001) 1.01

Neural and orofacial defects in Folp1 knockout mice [corrected]. Birth Defects Res A Clin Mol Teratol (2003) 1.00

Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett (2003) 0.98

Spatial and temporal expression of folate-binding protein 1 (Fbp1) is closely associated with anterior neural tube closure in mice. Dev Dyn (2003) 0.96

Appropriate use of animal models in the assessment of risk during prenatal development: an illustration using inorganic arsenic. Teratology (2000) 0.93

Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart. BMC Dev Biol (2003) 0.93

Folic acid alone prevents neural tube defects: evidence from the China study. Epidemiology (2002) 0.92

Expression patterns of folate binding proteins one and two in the developing mouse embryo. Mol Genet Metab (1999) 0.88

In vivo reduction of arsenate in mice and rabbits. Environ Res (1983) 0.87

Genetic polymorphism (G80A) of reduced folate carrier gene in ethnic populations. Mol Genet Metab (2001) 0.85

Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. Birth Defects Res A Clin Mol Teratol (2003) 0.84

Gene expression profiling within the developing neural tube. Neurochem Res (2002) 0.82

Lack of association between mutations in the folate receptor-alpha gene and spina bifida. Am J Med Genet (1998) 0.82

Effect of arsenite, maternal age, and embryonic sex on spina bifida, exencephaly, and resorption rates in the splotch mouse. Birth Defects Res A Clin Mol Teratol (2003) 0.81

Selective expression of the high-affinity isoform of the folate receptor (FR-alpha) in the human placental syncytiotrophoblast and choriocarcinoma cells. Biochim Biophys Acta (1994) 0.81

Teratogen update: inorganic arsenic. Teratology (2001) 0.81

Articles by these authors

Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med (2002) 11.20

Promoter features related to tissue specificity as measured by Shannon entropy. Genome Biol (2005) 5.19

Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr (2007) 4.37

Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med (2004) 4.34

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A (2002) 4.22

Autoantibodies to folate receptors in the cerebral folate deficiency syndrome. N Engl J Med (2005) 3.17

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr (2004) 3.00

Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst (2003) 2.92

A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev (2007) 2.91

The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65

Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Circulation (2011) 2.62

C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circ Cardiovasc Qual Outcomes (2008) 2.50

Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism. Am J Med Genet B Neuropsychiatr Genet (2006) 2.44

Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community. Circulation (2010) 2.32

Neural tube defects and folate: case far from closed. Nat Rev Neurosci (2006) 2.30

Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med (2005) 2.29

Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr (2006) 2.25

A new partner for the international knockout mouse consortium. Cell (2007) 2.23

Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment. Arthritis Rheum (2011) 2.21

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res (2008) 2.08

Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet (2008) 2.07

A multi-marker approach to predict incident CKD and microalbuminuria. J Am Soc Nephrol (2010) 1.95

Folic acid intake from fortification in United States exceeds predictions. J Nutr (2002) 1.94

Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies? Epidemiology (2002) 1.93

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol (2009) 1.90

Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. FASEB J (2009) 1.89

The continuing challenge of understanding, preventing, and treating neural tube defects. Science (2013) 1.86

Variation in IRF6 contributes to nonsyndromic cleft lip and palate. Am J Med Genet A (2005) 1.82

A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry. Anal Chem (2002) 1.81

118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet (2009) 1.74

Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr (2006) 1.71

Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial. Am J Clin Nutr (2004) 1.70

Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. Bone (2005) 1.69

High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke (2008) 1.67

Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour. Arterioscler Thromb Vasc Biol (2002) 1.66

Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation (2007) 1.65

Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging. Am J Med (2002) 1.63

Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology (2004) 1.63

A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. Blood (2011) 1.62

Relationship between homocysteine and mortality in chronic kidney disease. Circulation (2006) 1.58

Methotrexate polyglutamate concentrations are not associated with disease control in rheumatoid arthritis patients receiving long-term methotrexate therapy. Arthritis Rheum (2010) 1.56

Arsenic on the hands of children after playing in playgrounds. Environ Health Perspect (2004) 1.52

Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. J Pediatr (2008) 1.52

Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Arch Neurol (2008) 1.50

The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry (2006) 1.50

Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology. J Nutr (2002) 1.47

Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. Cell Metab (2013) 1.45

Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr (2011) 1.43

Biomarkers of folate status in NHANES: a roundtable summary. Am J Clin Nutr (2011) 1.43

Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. Am J Clin Nutr (2008) 1.42

Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proc Natl Acad Sci U S A (2011) 1.38

B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice. Proc Natl Acad Sci U S A (2008) 1.37

Novel mutations in VANGL1 in neural tube defects. Hum Mutat (2009) 1.37

Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004. Am J Clin Nutr (2008) 1.37

Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study. Eur Heart J (2004) 1.37

Mechanisms of DNA damage, DNA hypomethylation, and tumor progression in the folate/methyl-deficient rat model of hepatocarcinogenesis. J Nutr (2003) 1.36

Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women. J Natl Cancer Inst (2005) 1.36

Circulating folic acid in plasma: relation to folic acid fortification. Am J Clin Nutr (2008) 1.35

The atherogenic effect of excess methionine intake. Proc Natl Acad Sci U S A (2003) 1.35

Multiple biomarkers and the risk of incident hypertension. Hypertension (2007) 1.34

Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism. Am J Clin Nutr (2005) 1.33

Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet. Age (Dordr) (2006) 1.33

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Hum Mol Genet (2009) 1.33

Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. Am J Clin Nutr (2010) 1.32

Homocysteine as a risk factor for coronary heart diseases and its association with inflammatory biomarkers, lipids and dietary factors. Atherosclerosis (2004) 1.30

Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction. JAMA (2003) 1.30

A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma. Am J Clin Nutr (2009) 1.28

Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci U S A (2002) 1.28

Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women. Am J Clin Nutr (2008) 1.26

Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation (2008) 1.26

Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab (2003) 1.25

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet. J Hepatol (2009) 1.23

Errors in development of fetuses and placentas from in vitro-produced bovine embryos. Theriogenology (2005) 1.23

Integration of DNA sample collection into a multi-site birth defects case-control study. Teratology (2002) 1.22

A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. J Nutr (2008) 1.22

A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism. Am J Med Genet B Neuropsychiatr Genet (2010) 1.19

Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. Am J Med Genet A (2005) 1.18

Choline and risk of neural tube defects in a folate-fortified population. Epidemiology (2009) 1.18

Mutational analysis of loxP sites for efficient Cre-mediated insertion into genomic DNA. Genesis (2003) 1.18

Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr (2005) 1.17

Arsenic speciation analysis. Talanta (2002) 1.17

A highly efficient method for porcine cloning by nuclear transfer using in vitro-matured oocytes. Cloning Stem Cells (2002) 1.17

Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. Am J Med Genet (2002) 1.17

Targeting Ras signaling through inhibition of carboxyl methylation: an unexpected property of methotrexate. Proc Natl Acad Sci U S A (2003) 1.17

Elevated serum methylmalonic acid concentrations are common among elderly Americans. J Nutr (2002) 1.17

Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides. J Nutr (2005) 1.17

Folic acid in early pregnancy: a public health success story. FASEB J (2010) 1.16

Maternal occupational exposure to polycyclic aromatic hydrocarbons: effects on gastroschisis among offspring in the National Birth Defects Prevention Study. Environ Health Perspect (2012) 1.16

Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid. Br J Nutr (2008) 1.15

Multimarker approach for the prediction of heart failure incidence in the community. Circulation (2010) 1.15

Enhancement of folates in plants through metabolic engineering. Proc Natl Acad Sci U S A (2004) 1.15

Prediagnostic plasma folate and the risk of death in patients with colorectal cancer. J Clin Oncol (2008) 1.14

3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res (2006) 1.14

Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest (2010) 1.14

Maternal diabetes alters transcriptional programs in the developing embryo. BMC Genomics (2009) 1.14

One-carbon metabolism biomarkers and risk of colon and rectal cancers. Cancer Epidemiol Biomarkers Prev (2008) 1.14