Published in Mol Endocrinol on March 01, 2002
Beta-cell growth and regeneration: replication is only part of the story. Diabetes (2010) 1.92
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab (2010) 1.88
The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas. PLoS One (2009) 1.25
Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes. Curr Diabetes Rev (2013) 1.21
Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes (2005) 1.20
The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning. Proc Natl Acad Sci U S A (2005) 1.19
Targeted disruption of the gene for the PAK5 kinase in mice. Mol Cell Biol (2003) 1.17
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem (2009) 1.09
Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1. Mol Cell Biol (2003) 1.08
Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function. J Biol Chem (2010) 1.07
Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene. J Biol Chem (2008) 1.03
Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation. Dev Biol (2012) 1.01
Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol (2010) 0.99
Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish. Dev Biol (2012) 0.94
Diabetes and stem cell function. Biomed Res Int (2015) 0.83
Development and regeneration in the endocrine pancreas. ISRN Endocrinol (2012) 0.79
Congenital hypothyroidism (cretinism) in neuroD2-deficient mice. Mol Cell Biol (2006) 0.78
Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice. Sci Rep (2016) 0.77
Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med (2006) 4.31
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev (2007) 3.81
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature (2005) 3.67
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A (2006) 2.59
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet (2006) 2.11
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development (2005) 2.00
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
The transcription factor Bhlhb4 is required for rod bipolar cell maturation. Neuron (2004) 1.69
Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. Mol Endocrinol (2003) 1.66
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A (2005) 1.65
Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res (2006) 1.61
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci (2003) 1.61
Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol (2008) 1.60
Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med (2003) 1.55
Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res (2008) 1.54
Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol (2003) 1.53
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49
Cadherin-11 increases migration and invasion of prostate cancer cells and enhances their interaction with osteoblasts. Cancer Res (2010) 1.46
Coup d'Etat: an orphan takes control. Endocr Rev (2011) 1.45
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol (2005) 1.45
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 1.43
The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development. Mol Cell Biol (2004) 1.39
Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiency. Proc Natl Acad Sci U S A (2007) 1.38
The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism. Cell Metab (2009) 1.38
International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev (2006) 1.38
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex (2007) 1.33
Haploinsufficiency of chicken ovalbumin upstream promoter transcription factor II in female reproduction. Mol Endocrinol (2005) 1.33
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest (2010) 1.30
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell (2008) 1.29
SRC-3/AIB1: transcriptional coactivator in oncogenesis. Acta Pharmacol Sin (2006) 1.27
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell (2008) 1.27
The role of BETA2/NeuroD1 in the development of the nervous system. Mol Neurobiol (2004) 1.26
Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol (2005) 1.25
COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis. Development (2010) 1.23
MKL1 mediates TGF-beta1-induced alpha-smooth muscle actin expression in human renal epithelial cells. Am J Physiol Renal Physiol (2008) 1.21
Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes (2005) 1.20
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A (2004) 1.19
Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res (2010) 1.19
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum. Dev Biol (2008) 1.18
Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics. Mol Cell (2013) 1.17
Essential roles of COUP-TFII in Leydig cell differentiation and male fertility. PLoS One (2008) 1.15
Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem (2009) 1.13
REGgamma modulates p53 activity by regulating its cellular localization. J Cell Sci (2010) 1.11
Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A (2002) 1.10
Altered traveling wave propagation and reduced endocochlear potential associated with cochlear dysplasia in the BETA2/NeuroD1 null mouse. J Assoc Res Otolaryngol (2007) 1.08
Inflammatory breast cancer (IBC): clues for targeted therapies. Breast Cancer Res Treat (2013) 1.08
A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells. Cancer Res (2007) 1.07
Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol (2006) 1.07
Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation. Proc Natl Acad Sci U S A (2011) 1.06
Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer. Oncogene (2003) 1.06
ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest (2012) 1.05
Androgen depletion up-regulates cadherin-11 expression in prostate cancer. J Pathol (2010) 1.04
Effects of manufacturing conditions on the adsorption capacity of heavy metal ions by Makino bamboo charcoal. Bioresour Technol (2008) 1.03
Artery and vein formation: a tug of war between different forces. EMBO Rep (2007) 1.02
Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell (2013) 1.01
Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD. Mol Endocrinol (2004) 1.01
Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol (2010) 1.01
The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci (2009) 1.00
BHLHB4 is a bHLH transcriptional regulator in pancreas and brain that marks the dimesencephalic boundary. Genomics (2002) 1.00
Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol (2004) 0.99
COUP-TFII is a major regulator of cell cycle and Notch signaling pathways. Mol Endocrinol (2012) 0.99
Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A (2005) 0.98
Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo. Mol Endocrinol (2010) 0.98
The expression profiles of nuclear receptors in the developing and adult kidney. Mol Endocrinol (2006) 0.97
Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization. Mol Endocrinol (2010) 0.97
Expression of the extracellular domain of OB-cadherin as an Fc fusion protein using bicistronic retroviral expression vector. Protein Expr Purif (2008) 0.96
Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res (2008) 0.96
Imaging and analysis of 3D tumor spheroids enriched for a cancer stem cell phenotype. J Biomol Screen (2010) 0.96
BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cells. Diabetes (2003) 0.96
Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lung. J Biol Chem (2008) 0.94
Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol (2005) 0.93
Presence of anaplastic lymphoma kinase in inflammatory breast cancer. Springerplus (2013) 0.92
COUP-TFII controls amygdala patterning by regulating neuropilin expression. Development (2012) 0.91
Preferential posterior cerebellum defect in BETA2/NeuroD1 knockout mice is the result of differential expression of BETA2/NeuroD1 along anterior-posterior axis. Dev Biol (2005) 0.91
The nuclear orphan receptor COUP-TFI is important for differentiation of oligodendrocytes. Dev Biol (2004) 0.89
The expression pattern of nuclear receptors during cerebellar development. Dev Dyn (2007) 0.89
Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer. J Clin Invest (2014) 0.88
COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. Development (2012) 0.87
Compensational regulation of bHLH transcription factors in the postnatal development of BETA2/NeuroD1-null retina. Mech Dev (2007) 0.87
Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution. Elife (2014) 0.86
Bortezomib-mediated inhibition of steroid receptor coactivator-3 degradation leads to activated Akt. Clin Cancer Res (2008) 0.86
Phytoremediation of heavy metal contaminated soil by Jatropha curcas. Ecotoxicology (2014) 0.85
Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology (2007) 0.84
Regulatory potential of COUP-TFs in development: stem/progenitor cells. Semin Cell Dev Biol (2013) 0.84
Limitations of commonly used internal controls for real-time RT-PCR analysis of renal epithelial-mesenchymal cell transition. Nephron Exp Nephrol (2005) 0.84
EP2 receptor mediates PGE2-induced cystogenesis of human renal epithelial cells. Am J Physiol Renal Physiol (2007) 0.84
Regulation of human Clara cell 10 kD protein expression by chicken ovalbumin upstream promoter transcription factors (COUP-TFs). Am J Respir Cell Mol Biol (2002) 0.83
Endocardial cushion morphogenesis and coronary vessel development require chicken ovalbumin upstream promoter-transcription factor II. Arterioscler Thromb Vasc Biol (2012) 0.82
Tpit-/-NeuroD1-/- mice reveal novel aspects of corticotroph development. Endocr Res (2004) 0.81