Published in Mol Endocrinol on June 25, 2012
The critical roles of COUP-TFII in tumor progression and metastasis. Cell Biosci (2014) 1.13
Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell (2013) 1.01
Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment. J Mol Med (Berl) (2017) 0.97
BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development. Development (2013) 0.94
SoxF factors and Notch regulate nr2f2 gene expression during venous differentiation in zebrafish. Dev Biol (2014) 0.89
Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol (2013) 0.87
Regulatory potential of COUP-TFs in development: stem/progenitor cells. Semin Cell Dev Biol (2013) 0.84
The role of the orphan nuclear receptor COUP-TFII in tumorigenesis. Acta Pharmacol Sin (2014) 0.84
Endocardial cushion morphogenesis and coronary vessel development require chicken ovalbumin upstream promoter-transcription factor II. Arterioscler Thromb Vasc Biol (2012) 0.82
Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms. PLoS Comput Biol (2014) 0.78
Choose your destiny: Make a cell fate decision with COUP-TFII. J Steroid Biochem Mol Biol (2015) 0.78
COUP-TFs and eye development. Biochim Biophys Acta (2014) 0.77
The Anti-Adipogenic Potential of COUP-TFII Is Mediated by Downregulation of the Notch Target Gene Hey1. PLoS One (2015) 0.76
Differential Expression Levels of Integrin α6 Enable the Selective Identification and Isolation of Atrial and Ventricular Cardiomyocytes. PLoS One (2015) 0.75
Human brain arteriovenous malformations express lymphatic-associated genes. Ann Clin Transl Neurol (2014) 0.75
FGF2 Stimulates COUP-TFII Expression via the MEK1/2 Pathway to Inhibit Osteoblast Differentiation in C3H10T1/2 Cells. PLoS One (2016) 0.75
Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4+ T cell effector functions. Cell Commun Signal (2014) 0.75
The biology of VEGF and its receptors. Nat Med (2003) 32.13
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell (1996) 13.95
Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol (2006) 13.12
Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol (2007) 7.75
HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol (2003) 7.32
Notch signaling is essential for vascular morphogenesis in mice. Genes Dev (2000) 6.88
Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (1993) 6.84
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol Cell Biol (1995) 6.26
Notch signaling: from the outside in. Dev Biol (2000) 6.06
sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell (2002) 5.66
Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development (2001) 5.46
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev (1994) 4.93
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet (1999) 4.55
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev (2004) 4.41
The E2F1-3 transcription factors are essential for cellular proliferation. Nature (2001) 4.37
Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev (2004) 4.14
Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development (1995) 4.05
Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma. Nat Med (2008) 3.98
A requirement for neuropilin-1 in embryonic vessel formation. Development (1999) 3.95
Regulation of the cyclin E gene by transcription factor E2F1. Proc Natl Acad Sci U S A (1995) 3.95
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev (2004) 3.95
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature (2005) 3.67
FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? Nat Rev Cancer (2008) 3.46
Maintenance of somite borders in mice requires the Delta homologue DII1. Nature (1997) 3.44
Gridlock signalling pathway fashions the first embryonic artery. Nature (2001) 3.30
The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev (1999) 3.14
gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science (2000) 2.90
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature (2000) 2.85
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase. Mol Cell Biol (1999) 2.84
Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling. Nat Rev Mol Cell Biol (2002) 2.63
Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev (1997) 2.43
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev (2005) 2.18
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development (2005) 2.06
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol (2006) 2.06
Positive and negative modulation of angiogenesis by VEGFR1 ligands. Sci Signal (2009) 2.03
Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling. Curr Biol (2006) 1.68
Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells. PLoS One (2008) 1.66
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 1.43
Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F. Oncogene (1998) 1.42
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest (2010) 1.30
COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site. Mol Cell Biol (1999) 1.28
Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res (2010) 1.19
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum. Dev Biol (2008) 1.18
COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells. J Biol Chem (1997) 1.18
VEGF function in vascular pathogenesis. Exp Cell Res (2005) 1.10
Artery and vein formation: a tug of war between different forces. EMBO Rep (2007) 1.02
Arteries, veins, Notch, and VEGF. Cold Spring Harb Symp Quant Biol (2002) 1.01
Hesr, a mediator of the Notch signaling, functions in heart and vessel development. Trends Cardiovasc Med (2005) 0.93
Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo. Mol Cell Biol (2006) 0.92
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell (2006) 10.50
MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (2008) 10.11
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature (2002) 7.71
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor. Cell (2005) 4.60
A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face. Cell (2002) 4.57
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J (2008) 4.49
Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med (2006) 4.31
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol (2008) 4.30
Negative regulation of the deacetylase SIRT1 by DBC1. Nature (2008) 4.29
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell (2005) 3.89
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev (2002) 3.83
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev (2007) 3.81
Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1. EMBO J (2003) 3.72
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature (2005) 3.67
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. Proc Natl Acad Sci U S A (2003) 3.52
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev (2002) 3.49
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase. Genes Dev (2003) 3.35
PTOP interacts with POT1 and regulates its localization to telomeres. Nat Cell Biol (2004) 3.33
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J Biol Chem (2005) 3.19
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09
Parc: a cytoplasmic anchor for p53. Cell (2003) 3.06
Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast. Mol Cell (2008) 3.01
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells. Immunity (2011) 3.01
Analysis of the human endogenous coregulator complexome. Cell (2011) 2.97
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95
Kindlin-2 (Mig-2): a co-activator of beta3 integrins. J Cell Biol (2008) 2.88
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins. J Biol Chem (2004) 2.76
ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation. Mol Cell Biol (2007) 2.69
The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev (2002) 2.60
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A (2006) 2.59
Structural basis for the autoinhibition of talin in regulating integrin activation. Mol Cell (2008) 2.53
Mechanism of magnesium activation of calcium-activated potassium channels. Nature (2002) 2.50
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. Mol Cell (2003) 2.47
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks. Cell (2004) 2.46
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
The lipid whisker model of the structure of oxidized cell membranes. J Biol Chem (2007) 2.31
Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells. Proc Natl Acad Sci U S A (2010) 2.25
Cohesin acetylation speeds the replication fork. Nature (2009) 2.23
The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility. J Biol Chem (2007) 2.20
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet (2006) 2.11
A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. J Biol Chem (2007) 2.09
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development (2005) 2.00
Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci U S A (2009) 2.00
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc Natl Acad Sci U S A (2003) 1.90
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood (2011) 1.86
Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Mol Cell Biol (2002) 1.86
VEGF-integrin interplay controls tumor growth and vascularization. Proc Natl Acad Sci U S A (2005) 1.84
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1. Mol Cell Biol (2004) 1.78
Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol (2005) 1.74
Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase. J Biol Chem (2004) 1.74
A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment. Mol Cell Biol (2004) 1.73
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A (2010) 1.72
Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation. Proc Natl Acad Sci U S A (2009) 1.71
Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses. Nature (2010) 1.71
ATR phosphorylates SMARCAL1 to prevent replication fork collapse. Genes Dev (2013) 1.70
A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev (2006) 1.70
The transcription factor Bhlhb4 is required for rod bipolar cell maturation. Neuron (2004) 1.69
Migfilin, a molecular switch in regulation of integrin activation. J Biol Chem (2008) 1.68
Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. Mol Endocrinol (2003) 1.66
Membrane-mediated structural transitions at the cytoplasmic face during integrin activation. Proc Natl Acad Sci U S A (2004) 1.66
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A (2005) 1.65
The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions. Mol Cell (2009) 1.62
Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res (2006) 1.61
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci (2003) 1.61
Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol (2008) 1.60
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites. J Cell Sci (2002) 1.58
Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. J Biol Chem (2009) 1.56
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res (2010) 1.56
Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med (2003) 1.55
Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res (2008) 1.54
Yeast Isw1p forms two separable complexes in vivo. Mol Cell Biol (2003) 1.53
OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. J Biol Chem (2009) 1.53
Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol (2003) 1.53
The MTA family proteins as novel histone H3 binding proteins. Cell Biosci (2013) 1.52