DAP-like kinase interacts with the rat homolog of Schizosaccharomyces pombe CDC5 protein, a factor involved in pre-mRNA splicing and required for G2/M phase transition.

PubWeight™: 0.86‹?›

🔗 View Article (PMC 101352)

Published in Nucleic Acids Res on March 15, 2002

Authors

Harry Engemann1, Volker Heinzel, Grit Page, Ute Preuss, Karl Heinz Scheidtmann

Author Affiliations

1: Institute of Genetics, University of Bonn, Roemerstrasse 164, D-53117 Bonn, Germany.

Articles cited by this

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc Natl Acad Sci U S A (1991) 15.52

Myb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes. Mol Cell Biol (1998) 10.34

High mobility of proteins in the mammalian cell nucleus. Nature (2000) 9.39

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nat Genet (1998) 4.16

A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies. J Cell Sci (1992) 3.91

Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1981) 3.87

The transcriptional role of PML and the nuclear body. Nat Cell Biol (2000) 3.80

The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells. Genes Dev (1995) 3.52

A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Mol Cell Biol (1993) 3.33

Polo-like kinases: a team that plays throughout mitosis. Genes Dev (1998) 2.95

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. J Cell Biol (1998) 2.69

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity. EMBO J (1997) 2.69

The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell (1996) 2.66

Polo-like kinases: positive regulators of cell division from start to finish. Curr Opin Cell Biol (1998) 2.63

Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I. Nature (1996) 2.45

An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2. EMBO J (1997) 2.41

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors. Proc Natl Acad Sci U S A (1994) 2.34

SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors. J Biol Chem (1996) 2.28

Systematic identification of mitotic phosphoproteins. Curr Biol (1997) 2.18

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. EMBO J (2000) 2.14

Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements. Mol Cell Biol (1999) 2.05

Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. Mol Cell Biol (1999) 1.92

ZIP kinase, a novel serine/threonine kinase which mediates apoptosis. Mol Cell Biol (1998) 1.88

Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing. J Biol Chem (1999) 1.87

DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. J Cell Biol (1999) 1.85

Isolation and sequencing of cDNA clones encoding alpha and beta subunits of Drosophila melanogaster casein kinase II. Mol Cell Biol (1987) 1.78

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. Mol Cell Biol (1996) 1.73

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing. Exp Cell Res (1998) 1.63

Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors. Proc Natl Acad Sci U S A (1998) 1.60

The Schizosaccharomyces pombe cdc5+ gene encodes an essential protein with homology to c-Myb. EMBO J (1994) 1.59

Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles. Biochem Biophys Res Commun (1998) 1.55

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases. Biochem J (1997) 1.49

Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis. Oncogene (1999) 1.43

The PML nuclear bodies: actors or extras? Curr Opin Genet Dev (1999) 1.40

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis. Mol Cell Biol (2000) 1.39

A cdc5+ homolog of a higher plant, Arabidopsis thaliana. Proc Natl Acad Sci U S A (1996) 1.38

RNA splicing: What has phosphorylation got to do with it? Curr Biol (1999) 1.33

Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones. Oncogene (1998) 1.32

The DAP kinase family of pro-apoptotic proteins: novel players in the apoptotic game. Bioessays (2001) 1.31

Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends Cell Biol (1997) 1.30

Pombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signaling. J Biol Chem (1997) 1.26

Rb binds c-Jun and activates transcription. EMBO J (1998) 1.25

A mammalian homolog of fission yeast Cdc5 regulates G2 progression and mitotic entry. J Biol Chem (1998) 1.16

NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry. J Biol Chem (2000) 1.15

Evidence that Myb-related CDC5 proteins are required for pre-mRNA splicing. Proc Natl Acad Sci U S A (1999) 1.14

AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis. FEBS Lett (1999) 1.09

Dynamic organization of pre-mRNA splicing factors. J Cell Biochem (1996) 1.06

C-terminal truncation of Dlk/ZIP kinase leads to abrogation of nuclear transport and high apoptotic activity. Oncogene (1999) 1.04

cdc2 kinase-mediated phosphorylation of splicing factor SF2/ASF. Biochem Biophys Res Commun (1998) 1.01

Apoptosis mediated by a novel leucine zipper protein Par-4. Apoptosis (1998) 0.92

Human Cdc5, a regulator of mitotic entry, can act as a site-specific DNA binding protein. J Cell Sci (2000) 0.88

Casein kinase II interacts with the bZIP domains of several transcription factors. Nucleic Acids Res (1998) 0.83

Differential expression of elongation factor-2, alpha4 phosphoprotein and Cdc5-like protein in prolactin-dependent/independent rat lymphoid cells. Mol Cell Endocrinol (1997) 0.77

Articles by these authors

Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase. Nucleic Acids Res (2003) 1.64

DNA substrate dependence of p53-mediated regulation of double-strand break repair. Mol Cell Biol (2002) 1.32

TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination. J Biol Chem (2004) 1.03

Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants. Nucleic Acids Res (2008) 0.98

Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis. Exp Cell Res (2005) 0.93

Par-4: a new activator of myosin phosphatase. Mol Biol Cell (2010) 0.91

The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation. J Biol Chem (2001) 0.90

Characterization of rat BLOS2/Ceap, a putative yeast She3 homolog, as interaction partner of apoptosis antagonizing transcription factor/Che-1. Biol Chem (2007) 0.86

Par-4 is an essential downstream target of DAP-like kinase (Dlk) in Dlk/Par-4-mediated apoptosis. Mol Biol Cell (2009) 0.85

Par-4-mediated recruitment of Amida to the actin cytoskeleton leads to the induction of apoptosis. Exp Cell Res (2005) 0.83

Ectopic expression of Par-4 leads to induction of apoptosis in CNS tumor cell lines. Int J Oncol (2005) 0.81

DAP-like kinase, a member of the death-associated protein kinase family, associates with centrosomes, centromers, and the contractile ring during mitosis. Eur J Cell Biol (2003) 0.81