Published in Eur J Immunol on April 01, 2002
CD45: all is not yet crystal clear. Immunology (2006) 1.30
Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice. J Immunol (2013) 1.09
Lyn kinase promotes erythroblast expansion and late-stage development. Blood (2006) 1.06
B cell-specific loss of Lyn kinase leads to autoimmunity. J Immunol (2013) 1.00
Targeted therapy in chronic lymphocytic leukemia: past, present, and future. Clin Ther (2013) 0.96
A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function. Mol Cell (2009) 0.96
Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growth in a murine model of lymphoma expressing Myc and Epstein-Barr virus LMP2A. Antiviral Res (2012) 0.88
Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn. J Virol (2008) 0.87
Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells. Eur J Immunol (2011) 0.81
Lyn deficiency affects B-cell maturation as well as survival. Eur J Immunol (2011) 0.79
The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K. Self Nonself (2010) 0.75
Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24
microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity (2007) 6.72
Practical application of pharmacotherapy with long-acting risperidone for patients with schizophrenia. Psychiatr Serv (2004) 2.94
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med (2002) 2.68
Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells. J Immunol (2009) 2.51
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood (2005) 2.35
T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis. Immunity (2011) 2.00
Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils. Nat Cell Biol (2006) 1.76
Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue. Blood (2004) 1.66
Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol (2010) 1.63
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling. Nat Immunol (2013) 1.60
Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J Immunol (2005) 1.51
Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development. Dev Cell (2006) 1.50
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol (2010) 1.49
MicroRNA 125b inhibition of B cell differentiation in germinal centers. Int Immunol (2010) 1.47
Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J Exp Med (2009) 1.46
The role of endothelial PI3Kgamma activity in neutrophil trafficking. Blood (2005) 1.46
Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation. Immunity (2008) 1.43
Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. J Biol Chem (2004) 1.40
Phospholipase C-gamma2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells. Blood (2005) 1.31
Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases. Nat Immunol (2002) 1.29
The PI3K p110delta is required for down-regulation of RAG expression in immature B cells. J Immunol (2007) 1.27
Immunological function in mice lacking the Rac-related GTPase RhoG. Mol Cell Biol (2004) 1.19
The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response. Mol Cell Biol (2007) 1.18
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion. Blood (2007) 1.18
The RNA binding protein Zfp36l1 is required for normal vascularisation and post-transcriptionally regulates VEGF expression. Dev Dyn (2006) 1.17
Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C. Blood (2002) 1.15
Rac GTPases play critical roles in early T-cell development. Blood (2008) 1.13
Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals. BMC Cell Biol (2006) 1.11
The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. J Immunol (2008) 1.04
Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability. Circ Res (2012) 1.03
B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta. Eur J Immunol (2008) 1.01
Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes. Blood (2010) 1.00
Tribbles-2 is a novel regulator of inflammatory activation of monocytes. Int Immunol (2008) 0.99
RhoG regulates gene expression and the actin cytoskeleton in lymphocytes. Oncogene (2003) 0.97
A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival. J Exp Med (2010) 0.97
Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma. J Immunol (2012) 0.97
Patients with schizophrenia previously stabilized on conventional depot antipsychotics experience significant clinical improvements following treatment with long-acting risperidone. Eur Psychiatry (2004) 0.96
Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS. Amyotroph Lateral Scler (2012) 0.95
Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3. Biochem J (2007) 0.95
Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization. Exp Cell Res (2005) 0.94
Vav proteins regulate peripheral B-cell survival. Blood (2005) 0.93
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK. Immunity (2003) 0.92
Vav proteins are required for B-lymphocyte responses to LPS. Blood (2005) 0.92
Signaling pathways in T follicular helper cells. J Immunol (2010) 0.91
Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation. Exp Cell Res (2009) 0.90
Differential regulation of TCR-mediated gene transcription by Vav family members. J Exp Med (2004) 0.90
Vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus. J Immunol (2004) 0.89
RhoG regulates the neutrophil NADPH oxidase. J Immunol (2006) 0.89
RNA-binding proteins as a point of convergence of the PI3K and p38 MAPK pathways. Front Immunol (2012) 0.89
Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection. Trends Immunol (2010) 0.88
Antimicrobial coating agents: can biofilm formation on a breast implant be prevented? J Plast Reconstr Aesthet Surg (2008) 0.87
Procedures to improve the repeatability of forced oscillation measurements in school-aged children. Respir Physiol Neurobiol (2011) 0.86
Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets. Platelets (2005) 0.85
Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes. Eur J Immunol (2005) 0.84
Regulation of B-cell differentiation by microRNAs and RNA-binding proteins. Biochem Soc Trans (2008) 0.84
PLCgamma2 regulates Bcl-2 levels and is required for survival rather than differentiation of marginal zone and follicular B cells. Eur J Immunol (2004) 0.83
MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis. J Clin Invest (2015) 0.82
Synergistic activation of PKD by the B cell antigen receptor and CD19 requires PI3K, Vav1 and PLCgamma. Cell Signal (2005) 0.82
The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae. PLoS One (2013) 0.81
Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6. RNA (2013) 0.81
Pharmacological inhibition of glycogen synthase kinase 3 regulates T cell development in vitro. PLoS One (2013) 0.81
The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells. Eur J Immunol (2004) 0.80
Academic highlights: guidelines for the use of long-acting injectable atypical antipsychotics. J Clin Psychiatry (2004) 0.80
Interaction of Ras with p110γ is required for thymic β-selection in the mouse. J Immunol (2011) 0.80
Switching stable patients with schizophrenia from depot and oral antipsychotics to long-acting injectable risperidone: reasons for switching and safety. Hum Psychopharmacol (2010) 0.79
Detection of protein-protein interactions by ribosome display and protein in situ immobilisation. N Biotechnol (2009) 0.78
The role of PI3K signalling in the B cell response to antigen. Adv Exp Med Biol (2009) 0.77
Increased day-to-day variability of forced oscillatory resistance in poorly controlled or persistent pediatric asthma. Chest (2014) 0.75
The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K. Self Nonself (2010) 0.75
Dosing patterns in Europe: Efficacy and safety of risperidone long-acting injectable in doses of 25, 37.5 and 50 mg. Int J Psychiatry Clin Pract (2009) 0.75
Early symptom progression rate is related to ALS outcome: a prospective population-based study. Neurology (2002) 0.75
Dancing on the Grid: using e-Science tools to extend choreographic research. Philos Trans A Math Phys Eng Sci (2009) 0.75
Synthesis of pyrrolo[2,3-d][1,2,3]thiadiazole-6-carboxylates via the Hurd-Mori reaction. Investigating the effect of the N-protecting group on the cyclization. Molecules (2005) 0.75
The Role of p110δ in the Development and Activation of B Lymphocytes. Adv Exp Med Biol (2015) 0.75
Imaging: MRS/MRI/PET/SPECT: summary. Amyotroph Lateral Scler Other Motor Neuron Disord (2002) 0.75
Differential requirements of PI3K subunits for BCR or BCR/CD19-induced ERK activation. Adv Exp Med Biol (2006) 0.75
Outsourcing can have great appeal. Health Estate (2002) 0.75
A UK panel consensus on the initiation of aripiprazole for the treatment of bipolar mania. Int J Psychiatry Clin Pract (2012) 0.75
Managing the aftermath of mania - Newcastle, 2 September 2005: Consensus Meeting Statement. J Psychopharmacol (2006) 0.75
Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer. Nature (2016) 0.75