Published in Mol Cell Biol on January 01, 2004
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SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. Mol Biol Cell (2004) 1.42
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A syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis. Dev Cell (2011) 1.31
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The small GTPase RhoG mediates glioblastoma cell invasion. Mol Cancer (2012) 0.98
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Actin cytoskeletal defects in immunodeficiency. Immunol Rev (2013) 0.90
Yersinia pseudotuberculosis virulence determinants invasin, YopE, and YopT modulate RhoG activity and localization. Infect Immun (2009) 0.87
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Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation. Science (2000) 1.46
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The GTPase Rho has a critical regulatory role in thymus development. EMBO J (1997) 1.32
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Control of pre-T cell proliferation and differentiation by the GTPase Rac-I. Nat Immunol (2000) 1.24
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Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24
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Practical application of pharmacotherapy with long-acting risperidone for patients with schizophrenia. Psychiatr Serv (2004) 2.94
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J Neurosci (2002) 2.80
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med (2002) 2.68
Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells. J Immunol (2009) 2.51
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood (2005) 2.35
Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration. J Neurosci (2007) 2.28
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med (2008) 2.19
Retracted The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A (2009) 2.15
T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis. Immunity (2011) 2.00
Evidence for a direct link between glutathione biosynthesis and stress defense gene expression in Arabidopsis. Plant Cell (2004) 1.97
Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6. J Immunol (2004) 1.83
Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils. Nat Cell Biol (2006) 1.76
Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue. Blood (2004) 1.66
Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol (2010) 1.63
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling. Nat Immunol (2013) 1.60
Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model. FASEB J (2006) 1.59
Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J Immunol (2004) 1.59
Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. J Neurosci (2006) 1.57
Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J Immunol (2005) 1.51
Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain. Brain Res (2007) 1.50
Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development. Dev Cell (2006) 1.50
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Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol (2010) 1.49
IL-9 promotes IL-13-dependent paneth cell hyperplasia and up-regulation of innate immunity mediators in intestinal mucosa. J Immunol (2009) 1.48
MicroRNA 125b inhibition of B cell differentiation in germinal centers. Int Immunol (2010) 1.47
Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J Exp Med (2009) 1.46
The role of endothelial PI3Kgamma activity in neutrophil trafficking. Blood (2005) 1.46
IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells. J Immunol (2007) 1.44
Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation. Immunity (2008) 1.43
Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. J Biol Chem (2004) 1.40
Phospholipase C-gamma2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells. Blood (2005) 1.31
Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases. Nat Immunol (2002) 1.29
The PI3K p110delta is required for down-regulation of RAG expression in immature B cells. J Immunol (2007) 1.27
Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22. Proc Natl Acad Sci U S A (2002) 1.22
Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron. Am J Physiol Renal Physiol (2008) 1.22
GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function. Brain Res Mol Brain Res (2003) 1.20
The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response. Mol Cell Biol (2007) 1.18
Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain. J Neurochem (2006) 1.18
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion. Blood (2007) 1.18
The RNA binding protein Zfp36l1 is required for normal vascularisation and post-transcriptionally regulates VEGF expression. Dev Dyn (2006) 1.17
Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease. Brain Res (2006) 1.15
Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C. Blood (2002) 1.15
Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis. J Neurochem (2008) 1.14
Rac GTPases play critical roles in early T-cell development. Blood (2008) 1.13
Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease. Eur J Neurosci (2006) 1.13
A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma. Biochem J (2004) 1.13
Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals. BMC Cell Biol (2006) 1.11
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Altered vesicular dopamine storage in Parkinson's disease: a premature demise. Trends Neurosci (2008) 1.10
A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease. Neurochem Int (2010) 1.10
Glutamate uptake is reduced in prefrontal cortex in Huntington's disease. Neurochem Res (2007) 1.10
Facilitated Integrated Mood Management for adults with bipolar disorder. Bipolar Disord (2012) 1.09
Presynaptic control of striatal dopamine neurotransmission in adult vesicular monoamine transporter 2 (VMAT2) mutant mice. J Neurochem (2003) 1.06
The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. J Immunol (2008) 1.04
Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability. Circ Res (2012) 1.03
B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta. Eur J Immunol (2008) 1.01
Immunohistochemical study of brain-derived neurotrophic factor and its receptor, TrkB, in the hippocampal formation of schizophrenic brains. Prog Neuropsychopharmacol Biol Psychiatry (2003) 1.00
Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes. Blood (2010) 1.00
Tribbles-2 is a novel regulator of inflammatory activation of monocytes. Int Immunol (2008) 0.99
RhoG regulates gene expression and the actin cytoskeleton in lymphocytes. Oncogene (2003) 0.97
A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival. J Exp Med (2010) 0.97
Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma. J Immunol (2012) 0.97
Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. Proc Natl Acad Sci U S A (2005) 0.96
Patients with schizophrenia previously stabilized on conventional depot antipsychotics experience significant clinical improvements following treatment with long-acting risperidone. Eur Psychiatry (2004) 0.96
Innate lymphoid cells in the airways. Eur J Immunol (2012) 0.96
Factors influencing hand washing behaviour in primary schools: process evaluation within a randomized controlled trial. Health Educ Res (2012) 0.96
Identification of cells expressing somatostatin receptor 2 in the gastrointestinal tract of Sstr2 knockout/lacZ knockin mice. J Comp Neurol (2002) 0.95
Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3. Biochem J (2007) 0.95
Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS. Amyotroph Lateral Scler (2012) 0.95
Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization. Exp Cell Res (2005) 0.94
Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities. Mol Cell Biol (2005) 0.94
Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation. Synapse (2009) 0.93
Vav proteins regulate peripheral B-cell survival. Blood (2005) 0.93
Leveraging social networks for toxicovigilance. J Med Toxicol (2013) 0.93
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK. Immunity (2003) 0.92
Adolescent perspectives on wearing accelerometers to measure physical activity in population-based trials. Eur J Public Health (2012) 0.92
Vav proteins are required for B-lymphocyte responses to LPS. Blood (2005) 0.92
Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum. Eur J Neurosci (2003) 0.92
Signaling pathways in T follicular helper cells. J Immunol (2010) 0.91
Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation. Exp Cell Res (2009) 0.90
Differential regulation of TCR-mediated gene transcription by Vav family members. J Exp Med (2004) 0.90
RNA-binding proteins as a point of convergence of the PI3K and p38 MAPK pathways. Front Immunol (2012) 0.89
RhoG regulates the neutrophil NADPH oxidase. J Immunol (2006) 0.89
Vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus. J Immunol (2004) 0.89
The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2. Eur J Immunol (2002) 0.89
Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection. Trends Immunol (2010) 0.88
Impaired B-1 and B-2 B cell development and atypical splenic B cell structures in IL-7 receptor-deficient mice. Eur J Immunol (2004) 0.88
A randomized, placebo-controlled, dose-escalation study to determine the safety, tolerability, and immunogenicity of an HPV-16 therapeutic vaccine in HIV-positive participants with oncogenic HPV infection of the anus. J Acquir Immune Defic Syndr (2009) 0.88
Comparative cellular distribution of GABAA and GABAB receptors in the human basal ganglia: immunohistochemical colocalization of the alpha 1 subunit of the GABAA receptor, and the GABABR1 and GABABR2 receptor subunits. J Comp Neurol (2004) 0.87
Antimicrobial coating agents: can biofilm formation on a breast implant be prevented? J Plast Reconstr Aesthet Surg (2008) 0.87
Absence of opioid withdrawal symptoms in patients receiving methadone and the protease inhibitor lopinavir-ritonavir. Clin Infect Dis (2002) 0.87