Published in Eur J Hum Genet on February 01, 2002
High-resolution mutation mapping reveals parallel experimental evolution in yeast. PLoS Biol (2006) 2.32
Analysis of pooled DNA samples on high density arrays without prior knowledge of differential hybridization rates. Nucleic Acids Res (2006) 1.88
Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels. Hum Genomics (2004) 1.71
A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays. Nucleic Acids Res (2005) 1.71
Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics (2005) 1.68
Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness. PLoS Genet (2010) 1.55
Extremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular disease. Circ Cardiovasc Genet (2010) 1.33
A genome-wide association study identifies multiple loci associated with mathematics ability and disability. Genes Brain Behav (2009) 1.25
Optimal two-stage design for case-control association analysis incorporating genotyping errors. Ann Hum Genet (2008) 1.12
High-resolution genetic mapping with pooled sequencing. BMC Bioinformatics (2012) 1.01
Family-based association tests for different family structures using pooled DNA. Ann Hum Genet (2005) 0.98
Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. Mol Psychiatry (2012) 0.89
An efficient haplotyping method with DNA pools. Nucleic Acids Res (2002) 0.84
An optimal DNA pooling strategy for progressive fine mapping. Genetica (2008) 0.82
SNP haplotype tagging from DNA pools of two individuals. BMC Bioinformatics (2003) 0.78
Machine learning approach for pooled DNA sample calibration. BMC Bioinformatics (2015) 0.75
A genome-wide association study of essential hypertension in an Australian population using a DNA pooling approach. Mol Genet Genomics (2016) 0.75
Genome sequencing in microfabricated high-density picolitre reactors. Nature (2005) 150.21
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Merlin--rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet (2001) 53.16
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet (2008) 15.89
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Properties of structured association approaches to detecting population stratification. Hum Hered (2004) 7.53
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet (2006) 7.49
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. Nat Genet (2006) 6.74
A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell (2006) 6.61
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet (2005) 6.61
Parental phenotypes in family-based association analysis. Am J Hum Genet (2004) 6.35
Ascertainment through family history of disease often decreases the power of family-based association studies. Behav Genet (2007) 6.06
DNA Pooling: a tool for large-scale association studies. Nat Rev Genet (2002) 5.66
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
Powerful regression-based quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet (2002) 5.20
The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry (2003) 5.15
Genomic inflation factors under polygenic inheritance. Eur J Hum Genet (2011) 4.89
A robust toolkit for functional profiling of the yeast genome. Mol Cell (2004) 4.69
Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006. Am J Med (2009) 4.53
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes (2007) 3.84
Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. JAMA (2005) 3.83
Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. Proc Natl Acad Sci U S A (2004) 3.73
Total synthesis of a functional designer eukaryotic chromosome. Science (2014) 3.31
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature (2011) 2.81
The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet (2008) 2.79
Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases. Genet Epidemiol (2011) 2.78
Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genet (2010) 2.68
Dissecting the phenotype in genome-wide association studies of psychiatric illness. Br J Psychiatry (2009) 2.65
Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals. Spine (Phila Pa 1976) (2009) 2.56
RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics. PLoS Pathog (2006) 2.44
Relapse prevention in patients with bipolar disorder: cognitive therapy outcome after 2 years. Am J Psychiatry (2005) 2.33
Phosphoproteomic analysis of Her2/neu signaling and inhibition. Proc Natl Acad Sci U S A (2006) 2.30
Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophr Res (2004) 2.30
A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr Res (2004) 2.24
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol (2005) 2.04
Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples. Arch Gen Psychiatry (2007) 2.04
Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2009) 2.03
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev (2008) 2.01
Gene synthesis demystified. Trends Biotechnol (2008) 2.00
Parental monitoring moderates the importance of genetic and environmental influences on adolescent smoking. J Abnorm Psychol (2007) 1.99
Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants. Cell (2008) 1.99
Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets. Hum Genet (2011) 1.93
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet (2010) 1.89
zCall: a rare variant caller for array-based genotyping: genetics and population analysis. Bioinformatics (2012) 1.87
Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects. Psychol Med (2007) 1.85
Genome-wide association study of suicide attempts in mood disorder patients. Am J Psychiatry (2010) 1.85
A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: outcome of the first year. Arch Gen Psychiatry (2003) 1.84
A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry (2009) 1.84
Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: computational morphometry study. Br J Psychiatry (2005) 1.83
Global synthetic-lethality analysis and yeast functional profiling. Trends Genet (2005) 1.82
Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Am J Psychiatry (2010) 1.82
Where have all the interactions gone? Estimating the coverage of two-hybrid protein interaction maps. PLoS Comput Biol (2007) 1.81
The positives, protocols, and perils of genome-wide association. Am J Med Genet B Neuropsychiatr Genet (2008) 1.73
Changing environmental influences on substance use across development. Twin Res Hum Genet (2007) 1.70
Genetic and environmental contributions to general cognitive ability through the first 16 years of life. Dev Psychol (2004) 1.68
The Promises and Pitfalls of Genoeconomics* Annu Rev Econom (2012) 1.66
Use of multivariate linkage analysis for dissection of a complex cognitive trait. Am J Hum Genet (2003) 1.62
A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds. J Child Psychol Psychiatry (2005) 1.62
Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions. Genome Res (2008) 1.61
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Acad Sci U S A (2009) 1.56
Cognitive style in bipolar disorder. Br J Psychiatry (2005) 1.55
Family-based association study of lithium-related and other candidate genes in bipolar disorder. Arch Gen Psychiatry (2008) 1.53
Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Arch Gen Psychiatry (2007) 1.53
Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proc Natl Acad Sci U S A (2008) 1.51
DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage. Am J Med Genet B Neuropsychiatr Genet (2008) 1.50
NeMo: Network Module identification in Cytoscape. BMC Bioinformatics (2010) 1.49
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet (2012) 1.49
Family dysfunction interacts with genes in the causation of antisocial symptoms. Behav Genet (2005) 1.49
Substantial shared genetic influences on schizophrenia and event-related potentials. Am J Psychiatry (2007) 1.48
Domestic violence is associated with environmental suppression of IQ in young children. Dev Psychopathol (2003) 1.47
Meta-analysis of magnetic resonance imaging brain morphometry studies in bipolar disorder. Biol Psychiatry (2004) 1.45
Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol (2014) 1.42
Teaching synthetic biology, bioinformatics and engineering to undergraduates: the interdisciplinary Build-a-Genome course. Genetics (2008) 1.41
A meta-analysis of association studies between the 10-repeat allele of a VNTR polymorphism in the 3'-UTR of dopamine transporter gene and attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet (2007) 1.36
Gene-based tests of association. PLoS Genet (2011) 1.34
Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) (2007) 1.32
Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Neuropsychopharmacology (2008) 1.29
Retracted Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Nature (2012) 1.29
Gray matter in first-episode schizophrenia before and after antipsychotic drug treatment. Anatomical likelihood estimation meta-analyses with sample size weighting. Schizophr Bull (2009) 1.26
Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene. Nucleic Acids Res (2004) 1.26
Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening. Am J Hum Genet (2011) 1.26
The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset. Ann Hum Genet (2006) 1.26
Whole genome linkage scan of recurrent depressive disorder from the depression network study. Hum Mol Genet (2005) 1.25
Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset. BMC Res Notes (2011) 1.24
Association of the Taq I allele in vitamin D receptor with degenerative disc disease and disc bulge in a Chinese population. Spine (Phila Pa 1976) (2006) 1.24