A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds.

PubWeight™: 1.62‹?› | Rank: Top 4%

🔗 View Article (PMID 16178934)

Published in J Child Psychol Psychiatry on October 01, 2005

Authors

Nicole Harlaar1, Lee M Butcher, Emma Meaburn, Pak Sham, Ian W Craig, Robert Plomin

Author Affiliations

1: Institute of Psychiatry, King's College London, London, UK.

Articles citing this

Common disorders are quantitative traits. Nat Rev Genet (2009) 4.34

Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Res Hum Genet (2012) 3.00

Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays. Genes Brain Behav (2008) 2.08

A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Behav Genet (2010) 1.85

Cumulative-genetic plasticity, parenting and adolescent self-regulation. J Child Psychol Psychiatry (2010) 1.56

The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA. J Child Psychol Psychiatry (2009) 1.26

Child development and molecular genetics: 14 years later. Child Dev (2012) 1.23

The future of genomics for developmentalists. Dev Psychopathol (2013) 1.21

Generalist genes and the Internet generation: etiology of learning abilities by web testing at age 10. Genes Brain Behav (2007) 1.20

Finding genes in child psychology and psychiatry: when are we going to be there? J Child Psychol Psychiatry (2005) 1.07

Quantitative genetics in the era of molecular genetics: learning abilities and disabilities as an example. J Am Acad Child Adolesc Psychiatry (2010) 1.05

Predicting educational achievement from DNA. Mol Psychiatry (2016) 0.99

The genetic and environmental etiology of high math performance in 10-year-old twins. Behav Genet (2009) 0.93

Gene-environment interaction in the etiology of mathematical ability using SNP sets. Behav Genet (2010) 0.88

The nature of nurture: a genomewide association scan for family chaos. Behav Genet (2008) 0.87

Commentary: missing heritability, polygenic scores, and gene-environment correlation. J Child Psychol Psychiatry (2013) 0.86

A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study. PLoS One (2012) 0.85

Association between the A1 allele of the DRD2 gene and reduced verbal abilities in adolescence and early adulthood. J Neural Transm (Vienna) (2010) 0.83

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities. BMC Genet (2010) 0.82

Dopaminergic polymorphisms and educational achievement: results from a longitudinal sample of Americans. Dev Psychol (2011) 0.82

The emergence of genomic psychology. Insights from genomic analyses might allow psychologists to understand, predict and modify human behaviour. EMBO Rep (2007) 0.79

Toward an Integration of Social and Biological Research. Soc Serv Rev (2006) 0.79

Genetics of learning abilities and disabilities: recent developments from the UK and possible directions for research in China. 2008. Behav Genet (2010) 0.76

Articles by these authors

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61

Role of genotype in the cycle of violence in maltreated children. Science (2002) 13.50

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02

Properties of structured association approaches to detecting population stratification. Hum Hered (2004) 7.53

Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44

Parental phenotypes in family-based association analysis. Am J Hum Genet (2004) 6.35

A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34

Ascertainment through family history of disease often decreases the power of family-based association studies. Behav Genet (2007) 6.06

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56

The genetic and environmental origins of learning abilities and disabilities in the early school years. Monogr Soc Res Child Dev (2007) 5.54

The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry (2003) 5.15

Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry (2005) 4.85

Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment. Am J Clin Nutr (2008) 4.79

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42

Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Res (2002) 4.32

Twins' Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence. Twin Res Hum Genet (2007) 4.19

Time to give up on a single explanation for autism. Nat Neurosci (2006) 3.87

Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. JAMA (2005) 3.83

Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab (2008) 3.80

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet (2010) 3.34

Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet (2010) 3.17

Genetic heterogeneity between the three components of the autism spectrum: a twin study. J Am Acad Child Adolesc Psychiatry (2006) 3.16

Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Res Hum Genet (2012) 3.00

Genetic influences on early word recognition abilities and disabilities: a study of 7-year-old twins. J Child Psychol Psychiatry (2005) 2.85

Generalist genes: implications for the cognitive sciences. Trends Cogn Sci (2006) 2.71

Evidence for substantial genetic risk for psychopathy in 7-year-olds. J Child Psychol Psychiatry (2005) 2.64

Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals. Spine (Phila Pa 1976) (2009) 2.56

Internet cognitive testing of large samples needed in genetic research. Twin Res Hum Genet (2007) 2.45

Relapse prevention in patients with bipolar disorder: cognitive therapy outcome after 2 years. Am J Psychiatry (2005) 2.33

Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans. Nucleic Acids Res (2006) 2.33

Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proc Natl Acad Sci U S A (2007) 2.32

Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophr Res (2004) 2.30

A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr Res (2004) 2.24

Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. J Child Psychol Psychiatry (2008) 2.21

ChAMP: 450k Chip Analysis Methylation Pipeline. Bioinformatics (2013) 2.21

Whole genome DNA methylation analysis based on high throughput sequencing technology. Methods (2010) 2.17

Genome-wide association study of major recurrent depression in the U.K. population. Am J Psychiatry (2010) 2.17

Genotyping pooled DNA on microarrays: a systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits. Behav Genet (2004) 2.14

Parental feeding style and the inter-generational transmission of obesity risk. Obes Res (2002) 2.10

Genetic and environmental influences on adolescent attachment. J Child Psychol Psychiatry (2013) 2.09

A longitudinal study of epigenetic variation in twins. Epigenetics (2010) 2.06

Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples. Arch Gen Psychiatry (2007) 2.04

The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02

Outcomes of early language delay: I. Predicting persistent and transient language difficulties at 3 and 4 years. J Speech Lang Hear Res (2003) 2.01

Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Arch Gen Psychiatry (2011) 1.91

SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Hum Mol Genet (2005) 1.91

Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects. Psychol Med (2007) 1.85

A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Behav Genet (2010) 1.85

A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: outcome of the first year. Arch Gen Psychiatry (2003) 1.84

Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: computational morphometry study. Br J Psychiatry (2005) 1.83

No genetic influence for childhood behavior problems from DNA analysis. J Am Acad Child Adolesc Psychiatry (2013) 1.79

Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) (2008) 1.77

A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples. Behav Genet (2009) 1.75

Identical genetic influences underpin behavior problems in adolescence and basic traits of personality. J Child Psychol Psychiatry (2013) 1.74

A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays. Nucleic Acids Res (2005) 1.71

Relationships between parental negativity and childhood antisocial behavior over time: a bidirectional effects model in a longitudinal genetically informative design. J Abnorm Child Psychol (2007) 1.71

Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc (2012) 1.70

Aetiology of the relationship between callous-unemotional traits and conduct problems in childhood. Br J Psychiatry Suppl (2007) 1.70

Genetic and environmental contributions to general cognitive ability through the first 16 years of life. Dev Psychol (2004) 1.68

Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics (2005) 1.68

The ABCs of Math: A Genetic Analysis of Mathematics and Its Links With Reading Ability and General Cognitive Ability. J Educ Psychol (2009) 1.66

Genetic, environmental and gender influences on attachment disorder behaviours. Br J Psychiatry (2007) 1.60

Socioeconomic status (SES) and children's intelligence (IQ): in a UK-representative sample SES moderates the environmental, not genetic, effect on IQ. PLoS One (2012) 1.56

Cognitive style in bipolar disorder. Br J Psychiatry (2005) 1.55

Genetic support for the dual nature of attention deficit hyperactivity disorder: substantial genetic overlap between the inattentive and hyperactive-impulsive components. J Abnorm Child Psychol (2007) 1.55

Phenotypic and genetic overlap between autistic traits at the extremes of the general population. J Am Acad Child Adolesc Psychiatry (2006) 1.54

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52

Brain monoamine oxidase A activity predicts trait aggression. J Neurosci (2008) 1.51

DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage. Am J Med Genet B Neuropsychiatr Genet (2008) 1.50

A twin study of anxiety-related behaviours in pre-school children. J Child Psychol Psychiatry (2003) 1.48

Substantial shared genetic influences on schizophrenia and event-related potentials. Am J Psychiatry (2007) 1.48

The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Dev Sci (2005) 1.47

Prosocial behavior from early to middle childhood: genetic and environmental influences on stability and change. Dev Psychol (2006) 1.46

Genetic evidence for bidirectional effects of early lexical and grammatical development. Child Dev (2003) 1.46

Meta-analysis of magnetic resonance imaging brain morphometry studies in bipolar disorder. Biol Psychiatry (2004) 1.45

Optimal selection strategies for QTL mapping using pooled DNA samples. Eur J Hum Genet (2002) 1.45

Nonshared environmental influences on individual differences in early behavioral development: a monozygotic twin differences study. Child Dev (2003) 1.43

Learning abilities and disabilities: generalist genes in early adolescence. Cogn Neuropsychiatry (2009) 1.42

Genetic influences in different aspects of language development: the etiology of language skills in 4.5-year-old twins. Child Dev (2005) 1.41

The etiology of behavior problems in 7-year-old twins: substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. J Abnorm Child Psychol (2005) 1.38

Genetic influences on the stability of attention-deficit/hyperactivity disorder symptoms from early to middle childhood. Biol Psychiatry (2005) 1.37

A meta-analysis of association studies between the 10-repeat allele of a VNTR polymorphism in the 3'-UTR of dopamine transporter gene and attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet (2007) 1.36

Genetic and environmental influences in adolescent peer socialization: evidence from two genetically sensitive designs. Child Dev (2004) 1.35