Published in Circulation on April 09, 2002
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Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice. J Clin Invest (2007) 2.23
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. FASEB J (2005) 1.52
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Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts. J Mol Cell Cardiol (2007) 1.23
The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure. Proc Natl Acad Sci U S A (2004) 1.22
Cardiac tissue engineering for replacement therapy. Heart Fail Rev (2003) 1.09
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Cell therapy enhances function of remote non-infarcted myocardium. J Mol Cell Cardiol (2009) 1.07
Fibroblast sheets co-cultured with endothelial progenitor cells improve cardiac function of infarcted hearts. J Artif Organs (2008) 1.06
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Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival. Mol Imaging Biol (2006) 0.93
The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium. PLoS One (2013) 0.86
Human embryonic stem cells for myocardial regeneration. Heart Fail Rev (2003) 0.86
Cardiac repair by embryonic stem-derived cells. Handb Exp Pharmacol (2006) 0.85
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New therapies for reducing post-myocardial left ventricular remodeling. Ann Transl Med (2015) 0.85
Cell therapy with bone marrow cells for myocardial regeneration. Antioxid Redox Signal (2009) 0.83
Cell membrane damage is involved in the impaired survival of bone marrow stem cells by oxidized low-density lipoprotein. J Cell Mol Med (2014) 0.83
N-cadherin determines individual variations in the therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells in a rat model of myocardial infarction. Mol Ther (2011) 0.82
Intravenous administration of atorvastatin-pretreated mesenchymal stem cells improves cardiac performance after acute myocardial infarction: role of CXCR4. Am J Transl Res (2015) 0.82
Autologous cardiomyotissue implantation promotes myocardial regeneration, decreases infarct size, and improves left ventricular function. Circulation (2010) 0.80
Non-invasive bioluminescence imaging of myoblast-mediated hypoxia-inducible factor-1 alpha gene transfer. Mol Imaging Biol (2011) 0.80
Synthetic matrices to serve as niches for muscle cell transplantation. Cells Tissues Organs (2011) 0.79
Derivation of functional ventricular cardiomyocytes using endogenous promoter sequence from murine embryonic stem cells. Stem Cell Res (2011) 0.78
Recent progress in therapeutic angiogenesis. Int J Biomed Sci (2007) 0.77
Cardiomyocyte transplantation into the failing heart-new therapeutic approach for heart failure? Heart Fail Rev (2003) 0.77
Development of a spontaneously beating vein by cardiomyocyte transplantation in the wall of the inferior vena cava in a rat: a pilot study. J Vasc Surg (2007) 0.76
AMPK-mediated cardioprotection of atorvastatin relates to the reduction of apoptosis and activation of autophagy in infarcted rat hearts. Am J Transl Res (2016) 0.75
Integrin β1 Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction. Front Pharmacol (2017) 0.75
Tissue engineering: construction of a multicellular 3D scaffold for the delivery of layered cell sheets. J Vis Exp (2014) 0.75
The Relationship Between Left Ventricular Fractional Shortening and Intravenous Administration of Stem Cells in Laboratory Rabbits Presenting Chronic Myocardial Infarction. Clujul Med (2015) 0.75
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med (2013) 19.87
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell (2010) 16.12
Integrated genomic characterization of endometrial carcinoma. Nature (2013) 14.29
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet (2006) 13.63
The somatic genomic landscape of glioblastoma. Cell (2013) 11.73
MicroRNA-133 controls cardiac hypertrophy. Nat Med (2007) 11.68
Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol (2012) 10.87
Epigenetic stem cell signature in cancer. Nat Genet (2006) 9.62
Pan-cancer patterns of somatic copy number alteration. Nat Genet (2013) 7.73
HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol (2003) 7.32
Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res (2005) 6.49
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res (2010) 6.03
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat Genet (2011) 5.70
Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation (2003) 5.20
Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Res (2011) 4.84
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn (2006) 4.68
Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation (2005) 4.03
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. J Mol Cell Cardiol (2002) 3.79
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol (2002) 3.61
The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc (2012) 3.45
ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med (2002) 3.36
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS One (2007) 3.30
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Res (2004) 3.23
A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II). J Am Coll Cardiol (2005) 3.15
Interplay between the cancer genome and epigenome. Cell (2013) 3.05
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med (2015) 3.00
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest (2009) 2.98
Inferring tumour purity and stromal and immune cell admixture from expression data. Nat Commun (2013) 2.94
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet (2009) 2.85
Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation (2012) 2.78
Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation (2006) 2.68
Cigarette smoking and colorectal cancer risk by molecularly defined subtypes. J Natl Cancer Inst (2010) 2.38
Notch signaling in vascular development. Arterioscler Thromb Vasc Biol (2003) 2.31
No-reflow phenomenon. Circulation (2002) 2.30
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest (2008) 2.19
Low-level processing of Illumina Infinium DNA Methylation BeadArrays. Nucleic Acids Res (2013) 2.19
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiol Biomarkers Prev (2008) 2.12
Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circ Res (2009) 2.12
Cardiovascular effects of cocaine. Circulation (2010) 2.05
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res (Phila) (2008) 2.04
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest (2010) 2.04
DNA methylation as a biomarker for cardiovascular disease risk. PLoS One (2010) 2.04
Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data. Genome Biol (2012) 2.02
Air pollution and cardiovascular injury epidemiology, toxicology, and mechanisms. J Am Coll Cardiol (2008) 2.02
Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques. Circulation (2005) 2.01
Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Cancer Res (2006) 1.99
Epigenetic analysis of KSHV latent and lytic genomes. PLoS Pathog (2010) 1.94
A comparison of cluster analysis methods using DNA methylation data. Bioinformatics (2004) 1.94
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling. PLoS One (2009) 1.90
Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res (2010) 1.85
Thickening of the infarcted wall by collagen injection improves left ventricular function in rats: a novel approach to preserve cardiac function after myocardial infarction. J Am Coll Cardiol (2005) 1.83
Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am J Cardiol (2005) 1.83
Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography. J Am Coll Cardiol (2007) 1.82
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest (2014) 1.82
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. EMBO J (2004) 1.78
DNA hypomethylation and ovarian cancer biology. Cancer Res (2004) 1.75
Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice. Cancer Res (2002) 1.73
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun (2013) 1.73
The landscape of microsatellite instability in colorectal and endometrial cancer genomes. Cell (2013) 1.68
Comparison of automated oscillometric versus auscultatory blood pressure measurement. Am J Cardiol (2010) 1.66
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation (2011) 1.66
DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines. PLoS One (2010) 1.65
Sensitive detection of DNA methylation. Ann N Y Acad Sci (2003) 1.65
Prognostic utility of erectile dysfunction for cardiovascular disease in younger men and those with diabetes. Am Heart J (2012) 1.65
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest (2012) 1.59
Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene (2002) 1.59
The Archon Genomics X PRIZE for whole human genome sequencing. Nat Genet (2010) 1.56
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. Gastroenterology (2007) 1.56
Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm. PLoS One (2007) 1.55
The second Princeton consensus on sexual dysfunction and cardiac risk: new guidelines for sexual medicine. J Sex Med (2006) 1.53
Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. Cancer Res (2006) 1.52
HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box. Arterioscler Thromb Vasc Biol (2005) 1.52
Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells. Stem Cells (2010) 1.50
Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities. Heart Fail Rev (2011) 1.49
Nesprin 1 is critical for nuclear positioning and anchorage. Hum Mol Genet (2009) 1.48
Washout of transplanted cells from the heart: a potential new hurdle for cell transplantation therapy. Cardiovasc Res (2005) 1.48
Effects of sildenafil on myocardial infarct size, microvascular function, and acute ischemic left ventricular dilation. Cardiovasc Res (2003) 1.47
Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue. Cancer Res (2010) 1.47
Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships. Hum Genet (2012) 1.47
The "no-reflow" phenomenon: basic science and clinical correlates. Heart (2002) 1.46
Discovery of multi-dimensional modules by integrative analysis of cancer genomic data. Nucleic Acids Res (2012) 1.46
The combined use of ibutilide as an active control with intensive electrocardiographic sampling and signal averaging as a sensitive method to assess the effects of tadalafil on the human QT interval. J Am Coll Cardiol (2005) 1.46
Transplantation of neonatal cardiomyocytes after permanent coronary artery occlusion increases regional blood flow of infarcted myocardium. J Mol Cell Cardiol (2003) 1.46