Published in Mol Cell Biol on May 01, 2002
Myc's broad reach. Genes Dev (2008) 7.56
Regulation of the human catalytic subunit of telomerase (hTERT). Gene (2012) 1.81
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation. EMBO J (2004) 1.64
UBF levels determine the number of active ribosomal RNA genes in mammals. J Cell Biol (2008) 1.57
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation. Proc Natl Acad Sci U S A (2009) 1.36
The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression. Proc Natl Acad Sci U S A (2005) 1.29
Drosophila growth and development in the absence of dMyc and dMnt. Dev Biol (2007) 1.13
The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster. Mol Cell Biol (2005) 1.11
Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis. Biochim Biophys Acta (2014) 1.02
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest. Mol Cell Biol (2008) 1.01
c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation. Nucleic Acids Res (2010) 1.01
Alcohol suppresses the granulopoietic response to pulmonary Streptococcus pneumoniae infection with enhancement of STAT3 signaling. J Immunol (2011) 0.98
Placental expression of estrogen receptor beta and its hormone binding variant--comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells. Reprod Biol Endocrinol (2003) 0.96
Rb and hematopoiesis: stem cells to anemia. Cell Div (2008) 0.93
Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils. Br J Pharmacol (2004) 0.85
MAB-10/NAB acts with LIN-29/EGR to regulate terminal differentiation and the transition from larva to adult in C. elegans. Development (2011) 0.82
Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation. Oncotarget (2016) 0.75
The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention. Clin Epigenetics (2011) 0.75
MYC Modulation around the CDK2/p27/SKP2 Axis. Genes (Basel) (2017) 0.75
Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev (1995) 13.66
Role of the INK4a locus in tumor suppression and cell mortality. Cell (1996) 11.41
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell (1996) 8.77
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell (1996) 8.41
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell (1996) 7.69
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur J Biochem (1997) 6.99
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature (1996) 6.67
Drosophila myc regulates cellular growth during development. Cell (1999) 5.66
Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature (1994) 5.12
Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome. Nature (1997) 4.82
Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res (1996) 4.48
Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science (1996) 3.74
Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev (1997) 3.45
Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. EMBO J (1999) 3.41
Identification of CDK4 as a target of c-MYC. Proc Natl Acad Sci U S A (2000) 3.38
CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis. Genes Dev (1998) 2.91
The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev (1996) 2.61
The retinoblastoma gene family: cousins with overlapping interests. Trends Genet (1998) 2.59
Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc. EMBO J (1996) 2.59
Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development. Genes Dev (1998) 2.39
Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). EMBO J (1999) 2.31
Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell (2001) 2.29
Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nat Genet (2000) 2.19
Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. Genes Dev (1997) 2.05
Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Mol Cell Biol (1997) 2.00
Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J (1995) 1.92
Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression. Genes Dev (2000) 1.87
Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth. Nature (1998) 1.82
A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells. Curr Biol (1999) 1.70
Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases. Proc Natl Acad Sci U S A (1999) 1.66
A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage. Proc Natl Acad Sci U S A (1993) 1.63
Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes. Oncogene (1997) 1.54
Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events. EMBO J (2000) 1.42
Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. EMBO J (1998) 1.39
Inhibition of cell proliferation by the Mad1 transcriptional repressor. Mol Cell Biol (1996) 1.35
Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells. Nat Med (1995) 1.32
p27(Kip1) regulates cell cycle withdrawal of late multipotent progenitor cells in the mammalian retina. Dev Biol (2000) 1.31
p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity. Mol Cell Biol (1997) 1.31
Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase. Blood (2000) 1.25
Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth. Cell Growth Differ (1998) 1.15
Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases. Genes Dev (1997) 1.10
The Mad protein family links transcriptional repression to cell differentiation. Cold Spring Harb Symp Quant Biol (1998) 1.02
Functional analysis of pRb2/p130 interaction with cyclins. Cancer Res (1996) 1.01
Features of macrophage differentiation induced by p19INK4d, a specific inhibitor of cyclin D-dependent kinases. Blood (1997) 0.97
The interactions of E2F with pRB and with p107 are regulated via the phosphorylation of pRB and p107 by a cyclin-dependent kinase. Oncogene (1995) 0.96
The role of p27kip1 in the in vitro differentiation of murine keratinocytes. Cell Growth Differ (1997) 0.93
Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation. Mol Cell Biol (1997) 0.91
Retinoid X receptor (RXR) agonist-induced activation of dominant-negative RXR-retinoic acid receptor alpha403 heterodimers is developmentally regulated during myeloid differentiation. Mol Cell Biol (1999) 0.84
Myc's broad reach. Genes Dev (2008) 7.56
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature (2007) 7.55
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat Cell Biol (2003) 7.02
Living with or without cyclins and cyclin-dependent kinases. Genes Dev (2004) 6.54
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc Natl Acad Sci U S A (2004) 5.37
A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy. N Engl J Med (2008) 5.11
CDK inhibitors: cell cycle regulators and beyond. Dev Cell (2008) 5.07
c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat Cell Biol (2005) 4.89
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev (2003) 4.73
Myc influences global chromatin structure. EMBO J (2006) 4.71
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev (2003) 4.68
High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr (2007) 4.61
Maternal vitamin D deficiency increases the risk of preeclampsia. J Clin Endocrinol Metab (2007) 4.16
Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation. Mol Cell (2003) 3.91
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat Cell Biol (2005) 3.80
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev (2002) 3.71
A new description of cellular quiescence. PLoS Biol (2006) 3.56
Developmental and species-divergent globin switching are driven by BCL11A. Nature (2009) 3.49
Pregnancy outcomes with weight gain above or below the 2009 Institute of Medicine guidelines. Obstet Gynecol (2013) 3.46
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell (2010) 3.43
Direct activation of RNA polymerase III transcription by c-Myc. Nature (2003) 3.32
Histone sumoylation is associated with transcriptional repression. Proc Natl Acad Sci U S A (2003) 3.18
p27Kip1 modulates cell migration through the regulation of RhoA activation. Genes Dev (2004) 3.16
Kinase-independent function of cyclin E. Mol Cell (2007) 3.03
Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype. Genes Dev (2007) 3.00
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev (2006) 2.89
Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. Cell Stem Cell (2008) 2.83
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. Nat Immunol (2008) 2.70
Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development (2005) 2.64
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev (2007) 2.57
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr Biol (2004) 2.45
Evaluation of NIH consensus criteria for classification of late acute and chronic GVHD. Blood (2009) 2.44
Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Mol Cell (2007) 2.38
Contemporary concepts of the pathogenesis and management of preeclampsia. JAMA (2002) 2.36
Tumor suppression and normal aging in mice with constitutively high p53 activity. Genes Dev (2006) 2.35
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity. J Clin Invest (2011) 2.34
Control of the reversibility of cellular quiescence by the transcriptional repressor HES1. Science (2008) 2.29
Subclassification of preeclampsia. Hypertens Pregnancy (2003) 2.25
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Mol Cell (2008) 2.14
The risk of preeclampsia rises with increasing prepregnancy body mass index. Ann Epidemiol (2005) 2.12
Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis. Genes Dev (2008) 2.05
A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression. Genes Dev (2006) 2.05
Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors? Nat Rev Cancer (2004) 1.99
Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment. Blood (2011) 1.96
Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J (2009) 1.94
Quantitative proteomic analysis of Myc oncoprotein function. EMBO J (2002) 1.89
Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes. Proc Natl Acad Sci U S A (2002) 1.89
Preventing and treating eclamptic seizures. BMJ (2002) 1.88
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. J Cell Biol (2004) 1.88
Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells. Nat Cell Biol (2005) 1.85
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy. Mol Cancer Ther (2011) 1.74
p27(Kip1) and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy. J Natl Cancer Inst (2006) 1.74
Direct regulation of RNA polymerase III transcription by RB, p53 and c-Myc. Cell Cycle (2003) 1.73
RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. J Exp Med (2006) 1.72
Periconceptional multivitamin use reduces the risk of preeclampsia. Am J Epidemiol (2006) 1.70
dMyc is required for larval growth and endoreplication in Drosophila. Development (2004) 1.69
Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis. Genome Res (2010) 1.69
Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation. Cell (2010) 1.67
First-trimester prediction of preeclampsia in nulliparous women at low risk. Obstet Gynecol (2012) 1.66
N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth. Cancer Res (2006) 1.64
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation. EMBO J (2004) 1.64
Maternal serum 25-hydroxyvitamin D concentrations are associated with small-for-gestational age births in white women. J Nutr (2010) 1.64
Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor. J Clin Endocrinol Metab (2005) 1.61
A mouse model for cyclin E-dependent genetic instability and tumorigenesis. Cancer Cell (2005) 1.59
Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy. Epidemiology (2007) 1.58
A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium. J Soc Gynecol Investig (2002) 1.57
Seroprevalence of antibodies to Chlamydia pneumoniae in women with preeclampsia. Obstet Gynecol (2003) 1.57
Inflammation and dyslipidemia related to risk of spontaneous preterm birth. Am J Epidemiol (2007) 1.57
Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia. Hypertension (2007) 1.56
The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder. Annu Rev Biophys (2014) 1.55
Race Disparities and Decreasing Birth Weight: Are All Babies Getting Smaller? Am J Epidemiol (2015) 1.53
An overview of MYC and its interactome. Cold Spring Harb Perspect Med (2014) 1.53
The mSin3A chromatin-modifying complex is essential for embryogenesis and T-cell development. Mol Cell Biol (2005) 1.51
N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1). Mol Cell (2004) 1.45
N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development. Proc Natl Acad Sci U S A (2006) 1.45
BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage. J Biol Chem (2004) 1.45
First trimester exposure to ambient air pollution, pregnancy complications and adverse birth outcomes in Allegheny County, PA. Matern Child Health J (2013) 1.44
Preeclampsia--a pressing problem: an executive summary of a National Institute of Child Health and Human Development workshop. Reprod Sci (2007) 1.42
T-cell intrinsic and extrinsic mechanisms of p27Kip1 in the regulation of CD8 T-cell memory. Immunol Cell Biol (2012) 1.41
Early pregnancy lipid concentrations and spontaneous preterm birth. Am J Obstet Gynecol (2007) 1.40
Prepregnancy obesity predicts poor vitamin D status in mothers and their neonates. J Nutr (2007) 1.37
Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1. EMBO J (2002) 1.36
Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT. Mol Cell Biol (2004) 1.35
Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery. Am J Obstet Gynecol (2006) 1.34
Essential functions of the histone demethylase lid. PLoS Genet (2010) 1.34
Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance. J Clin Endocrinol Metab (2004) 1.34
Accuracy and reliability of maternal recall of infant birth weight among older women. Ann Epidemiol (2005) 1.33
Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling. PLoS One (2011) 1.31
Impairment of endothelial function in women with a history of preeclampsia: an indicator of cardiovascular risk. Am J Physiol Heart Circ Physiol (2004) 1.30
Redefining preeclampsia using placenta-derived biomarkers. Hypertension (2013) 1.30
Myc: a weapon of mass destruction. Cell (2004) 1.29
Myc stimulates B lymphocyte differentiation and amplifies calcium signaling. J Cell Biol (2007) 1.29
Association of periconceptional multivitamin use and risk of preterm or small-for-gestational-age births. Am J Epidemiol (2007) 1.29
Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells. J Clin Invest (2009) 1.28
The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection. Cell Cycle (2007) 1.28
Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer. Clin Cancer Res (2012) 1.26
Strategy for standardization of preeclampsia research study design. Hypertension (2014) 1.25
Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo. Genes Dev (2008) 1.25
Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation. EMBO J (2008) 1.23