Published in Oncogene on April 11, 2002
Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest (2005) 8.45
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol (2003) 3.54
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol (2003) 3.52
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J (2005) 2.63
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J (2009) 2.08
Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia. Am J Respir Crit Care Med (2011) 1.57
Mitochondria and endoplasmic reticulum: the lethal interorganelle cross-talk. J Bioenerg Biomembr (2005) 1.39
The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis. Proc Natl Acad Sci U S A (2004) 1.26
Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK). J Biol Chem (2011) 1.24
BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes. Oncogene (2008) 1.23
Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis. J Cell Biol (2007) 1.14
Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication. J Virol (2008) 1.05
The essential role of evasion from cell death in cancer. Adv Cancer Res (2011) 1.05
The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death. J Cell Biol (2008) 1.04
Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics. Biochim Biophys Acta (2014) 1.00
TGF-beta induces apoptosis in human B cells by transcriptional regulation of BIK and BCL-XL. Cell Death Differ (2009) 0.97
Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling. Mol Cell (2012) 0.96
Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis. J Virol (2007) 0.93
Human embryonic stem cells express elevated levels of multiple pro-apoptotic BCL-2 family members. PLoS One (2011) 0.92
A molecular analysis by gene expression profiling reveals Bik/NBK overexpression in sporadic breast tumor samples of Mexican females. BMC Cancer (2005) 0.91
Getting away with murder: how does the BCL-2 family of proteins kill with immunity? Ann N Y Acad Sci (2013) 0.91
BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma. Br J Cancer (2010) 0.91
Expression and function of bcl-2 proteins in melanoma. Curr Genomics (2008) 0.90
Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin. J Biol Chem (2012) 0.90
Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival. J Bioenerg Biomembr (2014) 0.85
BH3-only proteins and their effects on cancer. Adv Exp Med Biol (2010) 0.83
Deletion of the pro-apoptotic endoplasmic reticulum stress response effector CHOP does not result in improved locomotor function after severe contusive spinal cord injury. J Neurotrauma (2011) 0.83
BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition? Mol Cancer Res (2009) 0.83
Data-driven modeling of SRC control on the mitochondrial pathway of apoptosis: implication for anticancer therapy optimization. PLoS Comput Biol (2013) 0.81
Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF-7 breast cancer cells. Int J Oncol (2013) 0.80
Repression of the proapoptotic cellular BIK/NBK gene by Epstein-Barr virus antagonizes transforming growth factor β1-induced B-cell apoptosis. J Virol (2014) 0.78
Neither loss of Bik alone, nor combined loss of Bik and Noxa, accelerate murine lymphoma development or render lymphoma cells resistant to DNA damaging drugs. Cell Death Dis (2012) 0.77
Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. Nat Commun (2017) 0.75
Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells. PLoS One (2017) 0.75
p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress. Cell Death Differ (2017) 0.75
Proteasome Stress Triggers Death of SH-SY5Y and T98G Cells via Different Cellular Mechanisms. Neurochem Res (2017) 0.75
Exploiting Cell Death Pathways for Inducible Cell Elimination to Modulate Graft-versus-Host-Disease. Biomedicines (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis. Proc Natl Acad Sci U S A (2007) 4.92
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol (2003) 3.54
Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene (2003) 3.32
Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions. JAMA (2003) 2.74
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J (2005) 2.63
Unique biology of Mcl-1: therapeutic opportunities in cancer. Curr Mol Med (2008) 2.22
Proapoptotic BID is an ATM effector in the DNA-damage response. Cell (2005) 2.21
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J (2009) 2.08
Asking questions changes behavior: mere measurement effects on frequency of blood donation. Health Psychol (2008) 2.04
BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization. J Biol Chem (2003) 1.83
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nat Cell Biol (2011) 1.76
The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol (2009) 1.60
Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis. EMBO J (2006) 1.59
BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem (2005) 1.58
BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria. J Biol Chem (2002) 1.52
BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex. Cell (2008) 1.51
BH3-ligand regulates access of MCL-1 to its E3 ligase. FEBS Lett (2005) 1.49
Factors affecting red blood cell storage age at the time of transfusion. Transfusion (2013) 1.47
The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum. Proc Natl Acad Sci U S A (2002) 1.45
Cellular distribution of Bcl-2 family proteins. Sci STKE (2003) 1.36
Bcl-2 and calcium: controversy beneath the surface. Oncogene (2004) 1.36
BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts. J Biol Chem (2003) 1.34
Mitochondrion-dependent N-terminal processing of outer membrane Mcl-1 protein removes an essential Mule/Lasu1 protein-binding site. J Biol Chem (2011) 1.31
Safety and immunogenicity of a trivalent, inactivated, mammalian cell culture-derived influenza vaccine in healthy adults, seniors, and children. Vaccine (2002) 1.29
Reactive oxygen species: stuck in the middle of neurodegeneration. J Alzheimers Dis (2010) 1.28
Bap29/31 influences the intracellular traffic of MHC class I molecules. J Immunol (2004) 1.22
Mitochondrial membrane dynamics, cristae remodelling and apoptosis. Biochim Biophys Acta (2006) 1.20
Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix. J Biol Chem (2003) 1.19
Which survey questions change behavior? Randomized controlled trial of mere measurement interventions. Health Psychol (2010) 1.19
Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle. Hum Mol Genet (2012) 1.14
Determinants of repeated blood donation among new and experienced blood donors. Transfusion (2007) 1.13
Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria. J Biol Chem (2003) 1.12
Declining value of preoperative autologous donation. Transfusion (2002) 1.07
Programming cancer cells for high expression levels of Mcl1. EMBO Rep (2013) 1.06
BAP31 and its caspase cleavage product regulate cell surface expression of tetraspanins and integrin-mediated cell survival. J Biol Chem (2005) 0.99
Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells. Mol Cell Biochem (2007) 0.96
BCL2-CISD2: An ER complex at the nexus of autophagy and calcium homeostasis? Autophagy (2012) 0.95
The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. Mol Cell Biol (2004) 0.92
Some feelings are more important: cognitive attitudes, affective attitudes, anticipated affect, and blood donation. Health Psychol (2012) 0.91
Therapeutic activation of caspases in cancer: a question of selectivity. Curr Opin Drug Discov Devel (2003) 0.91
The resident endoplasmic reticulum protein, BAP31, associates with gamma-actin and myosin B heavy chain. Eur J Biochem (2003) 0.90
Mitochondria: joining forces to thwart cell death. Biochim Biophys Acta (2009) 0.90
Molecular dynamics study of small molecule inhibitors of the Bcl-2 family. Proteins (2011) 0.89
Skin cells, but not T cells, are resistant to indoleamine 2, 3-dioxygenase (IDO) expressed by allogeneic fibroblasts. Wound Repair Regen (2008) 0.86
Phase I, randomized, controlled trial to study the reactogenicity and immunogenicity of a nasal, inactivated trivalent influenza virus vaccine in healthy adults. Hum Vaccin (2005) 0.85
The effects of a phone call prompt on subsequent blood donation among first-time donors. Transfusion (2011) 0.85
Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism. J Biol Chem (2011) 0.84
Genetic analysis of B55alpha/Cdc55 protein phosphatase 2A subunits: association with the adenovirus E4orf4 protein. J Virol (2010) 0.82
Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum. EMBO J (2011) 0.82
The precautionary principle in blood safety: not quite the same as aiming for zero risk. Transfus Med Rev (2011) 0.80
BIM, PUMA, and the achilles' heel of oncogene addiction. Sci Signal (2013) 0.80
Predicting first lifetime plasma donation among whole blood donors. Transfusion (2013) 0.78
Estimates of risk of window-period transmission of blood-borne viral diseases in Quebec. CMAJ (2004) 0.78
Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31. Biochim Biophys Acta (2011) 0.77
An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro. Chembiochem (2010) 0.76
Implementation intentions intervention among temporarily deferred novice blood donors. Transfusion (2012) 0.76
Improving organ donation in Canada. CMAJ (2007) 0.75
Evolution of Corneal Transplantation in the Province of Quebec From 2000 to 2011. Cornea (2015) 0.75