Published in Cell on June 13, 2008
The ubiquitylation machinery of the endoplasmic reticulum. Nature (2009) 2.66
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J (2009) 2.08
The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels. Nat Neurosci (2010) 1.96
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J (2010) 1.57
The mammalian endoplasmic reticulum-associated degradation system. Cold Spring Harb Perspect Biol (2013) 1.50
BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol. Nat Cell Biol (2011) 1.45
Protein folding and quality control in the ER. Cold Spring Harb Perspect Biol (2011) 1.33
The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508. Mol Biol Cell (2010) 1.23
Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2. J Clin Invest (2010) 1.19
Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31. PLoS One (2013) 1.09
Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy. Cell Res (2011) 1.07
CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress. Cell Rep (2013) 1.04
Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation. EMBO J (2009) 1.04
A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum. PLoS Pathog (2014) 1.02
Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps. J Biol Chem (2010) 0.99
A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum. Cell Death Differ (2012) 0.98
Membrane-Associated RING-CH proteins associate with Bap31 and target CD81 and CD44 to lysosomes. PLoS One (2010) 0.95
TIGAR2: sensitive and accurate estimation of transcript isoform expression with longer RNA-Seq reads. BMC Genomics (2014) 0.93
Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study. Vet Pathol (2016) 0.91
Efficient detection of proteins retro-translocated from the ER to the cytosol by in vivo biotinylation. PLoS One (2011) 0.85
Inter-species complementation of the translocon beta subunit requires only its transmembrane domain. PLoS One (2008) 0.85
Yet1p and Yet3p, the yeast homologs of BAP29 and BAP31, interact with the endoplasmic reticulum translocation apparatus and are required for inositol prototrophy. J Biol Chem (2010) 0.84
Molecular pathogenesis of spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins. EMBO Mol Med (2014) 0.83
Ascorbate peroxidase proximity labeling coupled with biochemical fractionation identifies promoters of endoplasmic reticulum mitochondrial contacts. J Biol Chem (2017) 0.83
Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum. EMBO J (2011) 0.82
Alteration of CFTR transmembrane span integration by disease-causing mutations. Mol Biol Cell (2011) 0.82
Yet1p-Yet3p interacts with Scs2p-Opi1p to regulate ER localization of the Opi1p repressor. Mol Biol Cell (2011) 0.82
Mutations in BCAP31 cause a severe X-linked phenotype with deafness, dystonia, and central hypomyelination and disorganize the Golgi apparatus. Am J Hum Genet (2013) 0.81
CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules. J Biol Chem (2013) 0.81
Ubiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation. J Biol Chem (2010) 0.81
RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem (2013) 0.81
Applications of proteomic technologies for understanding the premature proteolysis of CFTR. Expert Rev Proteomics (2010) 0.80
Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment. Acta Neuropathol Commun (2013) 0.79
Proteasome inhibition compromises direct retention of cytochrome P450 2C2 in the endoplasmic reticulum. Exp Cell Res (2008) 0.79
The C-terminal amino acid of the MHC-I heavy chain is critical for binding to Derlin-1 in human cytomegalovirus US11-induced MHC-I degradation. PLoS One (2013) 0.78
Development of CFTR Structure. Front Pharmacol (2012) 0.77
Derlin-1 regulates mutant VCP-linked pathogenesis and endoplasmic reticulum stress-induced apoptosis. PLoS Genet (2014) 0.77
Protein-Protein Interactions of Viroporins in Coronaviruses and Paramyxoviruses: New Targets for Antivirals? Viruses (2015) 0.77
A novel UGGT1 and p97-dependent checkpoint for native ectodomains with ionizable intramembrane residue. Mol Biol Cell (2015) 0.76
VAMP-associated Proteins (VAP) as Receptors That Couple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Proteostasis with Lipid Homeostasis. J Biol Chem (2016) 0.75
Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases. PLoS One (2016) 0.75
BAP31 is involved in T cell activation through TCR signal pathways. Sci Rep (2017) 0.75
BAP31, a promising target for the immunotherapy of malignant melanomas. J Exp Clin Cancer Res (2015) 0.75
Analysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches. PLoS One (2016) 0.75
Profiling of Host Cell Response to Successive Canine Parvovirus Infection Based on Kinetic Proteomic Change Identification. Sci Rep (2016) 0.75
Plant-specific 4/1 polypeptide interacts with an endoplasmic reticulum protein related to human BAP31. Planta (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol (2004) 6.35
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis. Proc Natl Acad Sci U S A (2007) 4.92
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol (2003) 3.54
Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition. Mol Biol Cell (2002) 3.36
Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene (2003) 3.32
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science (2008) 3.18
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J (2005) 2.63
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med (2006) 2.34
Unique biology of Mcl-1: therapeutic opportunities in cancer. Curr Mol Med (2008) 2.22
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J (2009) 2.08
Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae. FEMS Immunol Med Microbiol (2002) 2.00
Drag&Drop cloning in yeast. Gene (2004) 1.93
Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR. Chem Biol (2011) 1.92
BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization. J Biol Chem (2003) 1.83
The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation. Nat Struct Mol Biol (2004) 1.78
Population genomics of drug resistance in Candida albicans. Proc Natl Acad Sci U S A (2002) 1.76
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nat Cell Biol (2011) 1.76
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. Aging (Albany NY) (2010) 1.76
Protein quality control in the ER: the recognition of misfolded proteins. Semin Cell Dev Biol (2010) 1.69
The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol (2009) 1.60
Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis. EMBO J (2006) 1.59
BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem (2005) 1.58
BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria. J Biol Chem (2002) 1.52
Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis. J Clin Invest (2007) 1.50
BH3-ligand regulates access of MCL-1 to its E3 ligase. FEBS Lett (2005) 1.49
Identifying regulatory subnetworks for a set of genes. Mol Cell Proteomics (2005) 1.48
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53. Oncogene (2002) 1.47
The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum. Proc Natl Acad Sci U S A (2002) 1.45
Localization of the lectin, ERp57 binding, and polypeptide binding sites of calnexin and calreticulin. J Biol Chem (2002) 1.42
A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases. Hum Mol Genet (2003) 1.40
CDC42 is required for polarized growth in human pathogen Candida albicans. Eukaryot Cell (2002) 1.40
Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association. Genes Dev (2006) 1.39
A structural overview of the PDI family of proteins. FEBS J (2010) 1.38
Cellular distribution of Bcl-2 family proteins. Sci STKE (2003) 1.36
Bcl-2 and calcium: controversy beneath the surface. Oncogene (2004) 1.36
Cold adaptation in budding yeast. Mol Biol Cell (2004) 1.36
Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol (2010) 1.36
Predicting subcellular localization via protein motif co-occurrence. Genome Res (2004) 1.36
Membrane lateral diffusion and capture of CFTR within transient confinement zones. Biophys J (2006) 1.36
Crystal structure of the bb' domains of the protein disulfide isomerase ERp57. Structure (2006) 1.33
Solution structure of the bb' domains of human protein disulfide isomerase. FEBS J (2009) 1.32
Mitochondrion-dependent N-terminal processing of outer membrane Mcl-1 protein removes an essential Mule/Lasu1 protein-binding site. J Biol Chem (2011) 1.31
Refining protein subcellular localization. PLoS Comput Biol (2005) 1.28
Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol (2010) 1.27
Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice. PLoS Genet (2009) 1.26
Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol (2007) 1.25
Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth. Mol Biol Cell (2003) 1.25
Correctors of protein trafficking defects identified by a novel high-throughput screening assay. Chembiochem (2007) 1.24
Nup53p is a target of two mitotic kinases, Cdk1p and Hrr25p. Traffic (2007) 1.24
Bap29/31 influences the intracellular traffic of MHC class I molecules. J Immunol (2004) 1.22
Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice. J Physiol (2007) 1.21
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. Mol Biol Cell (2007) 1.20
Mitochondrial membrane dynamics, cristae remodelling and apoptosis. Biochim Biophys Acta (2006) 1.20
Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix. J Biol Chem (2003) 1.19
Oxidant stress suppresses CFTR expression. Am J Physiol Cell Physiol (2005) 1.19
Lectin control of protein folding and sorting in the secretory pathway. Trends Biochem Sci (2003) 1.17
Specific interaction of ERp57 and calnexin determined by NMR spectroscopy and an ER two-hybrid system. EMBO J (2004) 1.16
Physiology of epithelial chloride and fluid secretion. Cold Spring Harb Perspect Med (2012) 1.16
Novel pharmacological strategies to treat cystic fibrosis. Trends Pharmacol Sci (2013) 1.16
Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3. J Physiol (2012) 1.14
Phosphorylation of CFTR by PKA promotes binding of the regulatory domain. EMBO J (2005) 1.14
Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle. Hum Mol Genet (2012) 1.14
Glycopeptide specificity of the secretory protein folding sensor UDP-glucose glycoprotein:glucosyltransferase. EMBO Rep (2003) 1.13
Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria. J Biol Chem (2003) 1.12
ATP release from human airway epithelial cells studied using a capillary cell culture system. J Physiol (2002) 1.12
Chemogenomic profiling predicts antifungal synergies. Mol Syst Biol (2009) 1.11
Role of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle. Am J Respir Cell Mol Biol (2008) 1.10
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell (2012) 1.07
Programming cancer cells for high expression levels of Mcl1. EMBO Rep (2013) 1.06
Structural basis of cyclophilin B binding by the calnexin/calreticulin P-domain. J Biol Chem (2010) 1.05
Trafficking of immature DeltaF508-CFTR to the plasma membrane and its detection by biotinylation. Biochem J (2009) 1.04
Genetic analysis of the interface between Cdc42p and the CRIB domain of Ste20p in Saccharomyces cerevisiae. Genetics (2003) 1.04
Investigating membrane protein dynamics in living cells. Biochem Cell Biol (2006) 1.04
Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor. Cancer Res (2003) 1.03
The secret life of CFTR as a calcium-activated chloride channel. J Physiol (2013) 1.01
Structure of the noncatalytic domains and global fold of the protein disulfide isomerase ERp72. Structure (2009) 1.00
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A (2003) 1.00
Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence. PLoS Pathog (2010) 1.00
BAP31 and its caspase cleavage product regulate cell surface expression of tetraspanins and integrin-mediated cell survival. J Biol Chem (2005) 0.99
Intracellular eukaryotic parasites have a distinct unfolded protein response. PLoS One (2011) 0.98
Organization of the Sec61 translocon, studied by high resolution native electrophoresis. J Proteome Res (2010) 0.97
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem (2013) 0.96
An interaction map of endoplasmic reticulum chaperones and foldases. Mol Cell Proteomics (2012) 0.96
Substance P stimulates CFTR-dependent fluid secretion by mouse tracheal submucosal glands. Pflugers Arch (2008) 0.96
BCL2-CISD2: An ER complex at the nexus of autophagy and calcium homeostasis? Autophagy (2012) 0.95
Basolateral chloride loading by the anion exchanger type 2: role in fluid secretion by the human airway epithelial cell line Calu-3. J Physiol (2012) 0.93
Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways. FASEB J (2011) 0.92
The ER glycoprotein quality control system. Curr Issues Mol Biol (2004) 0.92
The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. Mol Cell Biol (2004) 0.92
Calnexin phosphorylation: linking cytoplasmic signalling to endoplasmic reticulum lumenal functions. Semin Cell Dev Biol (2010) 0.91
Therapeutic activation of caspases in cancer: a question of selectivity. Curr Opin Drug Discov Devel (2003) 0.91