Published in Stem Cell Reports on June 04, 2013
Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature (2013) 2.29
Heterogeneity and plasticity of epidermal stem cells. Development (2014) 1.08
Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin. Nat Cell Biol (2016) 0.96
Markers of epidermal stem cell subpopulations in adult mammalian skin. Cold Spring Harb Perspect Med (2014) 0.95
Defining the clonal dynamics leading to mouse skin tumour initiation. Nature (2016) 0.88
Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium. Proc Natl Acad Sci U S A (2015) 0.87
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Nat Commun (2014) 0.87
Lineage analysis of epidermal stem cells. Cold Spring Harb Perspect Med (2014) 0.86
Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages. Nat Commun (2016) 0.83
BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions. Stem Cell Reports (2014) 0.81
Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity. Cell Rep (2016) 0.80
Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO J (2016) 0.80
Fate and plasticity of the epidermis in response to congenital activation of BRAF. J Invest Dermatol (2014) 0.79
The Role of Symmetric Stem Cell Divisions in Tissue Homeostasis. PLoS Comput Biol (2015) 0.78
Modeling cutaneous squamous carcinoma development in the mouse. Cold Spring Harb Perspect Med (2014) 0.78
Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration. Cell Cycle (2015) 0.77
Three-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon Microscopy. PLoS One (2016) 0.75
Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD. BMC Evol Biol (2015) 0.75
Bimodal skin progenitors-a matter of place and time. EMBO J (2016) 0.75
Stem cell heterogeneity revealed. Nat Cell Biol (2016) 0.75
Senescent Atrophic Epidermis Retains Lrig1+ Stem Cells and Loses Wnt Signaling, a Phenotype Shared with CD44KO Mice. PLoS One (2017) 0.75
A single type of progenitor cell maintains normal epidermis. Nature (2007) 6.32
The human keratins: biology and pathology. Histochem Cell Biol (2008) 5.13
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination. FEBS Lett (2000) 4.03
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development (2003) 3.84
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell (2009) 3.44
Distinct contribution of stem and progenitor cells to epidermal maintenance. Nature (2012) 3.44
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development (2004) 3.24
Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol (2007) 2.82
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development (2002) 2.79
Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell (2005) 2.71
A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J (1992) 2.51
The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate. Dev Cell (2010) 2.41
Identifying the cellular origin of squamous skin tumors. Proc Natl Acad Sci U S A (2011) 2.24
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell (1995) 2.24
Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23
One remarkable molecule: filaggrin. J Invest Dermatol (2011) 2.10
Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell (2007) 1.91
Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development (2002) 1.70
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development (2006) 1.66
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett (2002) 1.51
A developmental study of the distribution and frequency of Langerhans cells in relation to formation of patterning in mouse tail epidermis. J Invest Dermatol (1977) 1.44
Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36
Mutations at the W locus affect survival of neural crest-derived melanocytes in the mouse. Mech Dev (1995) 1.28
Generation of melanocytes from neural crest cells. Pigment Cell Melanoma Res (2011) 1.18
Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer. Cold Spring Harb Symp Quant Biol (2008) 1.11
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J Invest Dermatol (2007) 1.11
The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle. J Biol Chem (1999) 1.10
Different consequences of beta1 integrin deletion in neonatal and adult mouse epidermis reveal a context-dependent role of integrins in regulating proliferation, differentiation, and intercellular communication. J Invest Dermatol (2005) 1.01
Hair follicles are required for optimal growth during lateral skin expansion. J Invest Dermatol (2009) 0.85
Expression of cytoplasmic antigens linked to orthokeratosis during the development of parakeratosis in newborn mouse tail epidermis. Differentiation (1983) 0.84
Selective suppression of two postnatally acquired 70 kD and 65 kD keratin proteins during continuous treatment of adult mouse tail epidermis with vitamin A. J Invest Dermatol (1987) 0.83
Autophagy mediates the mitotic senescence transition. Genes Dev (2009) 6.80
An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer. Genome Biol (2007) 4.33
Extracellular-matrix tethering regulates stem-cell fate. Nat Mater (2012) 3.94
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development (2003) 3.84
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell (2013) 3.47
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell (2009) 3.44
Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol (2010) 3.33
Stem cell depletion through epidermal deletion of Rac1. Science (2005) 3.26
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development (2004) 3.24
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A (2006) 2.91
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development (2009) 2.82
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development (2002) 2.79
Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell (2005) 2.71
Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer (2003) 2.69
Lineage tracing. Cell (2012) 2.67
An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution. J Invest Dermatol (2007) 2.53
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol (2012) 2.51
Stem cells are dispensable for lung homeostasis but restore airways after injury. Proc Natl Acad Sci U S A (2009) 2.28
Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23
Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development (2003) 2.23
Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development (2006) 2.06
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04
A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development (2002) 2.04
Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell (2007) 1.91
The basement membrane of hair follicle stem cells is a muscle cell niche. Cell (2011) 1.88
Defining dermal adipose tissue. Exp Dermatol (2014) 1.84
Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering. PLoS Biol (2011) 1.82
Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3. Nat Cell Biol (2008) 1.79
New roles for integrins in squamous-cell carcinoma. Nat Rev Cancer (2006) 1.75
Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nat Protoc (2010) 1.72
Hair follicle dermal papilla cells at a glance. J Cell Sci (2011) 1.72
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors. Curr Biol (2006) 1.71
Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol (2006) 1.65
Designer skin: lineage commitment in postnatal epidermis. Trends Cell Biol (2002) 1.59
Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Curr Biol (2003) 1.54
The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS One (2008) 1.53
Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat Genet (2005) 1.51
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet (2011) 1.48
Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS One (2007) 1.45
Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. Development (2011) 1.43
Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis. Development (2003) 1.42
Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med (2006) 1.40
Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form. Hum Mutat (2008) 1.39
Suprabasal alpha6beta4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFbeta signalling. J Cell Sci (2003) 1.37
Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. J Cell Sci (2003) 1.37
Epidermal stem cells are retained in vivo throughout skin aging. Aging Cell (2008) 1.31
Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and -negative cells in vitro and in vivo. J Invest Dermatol (2011) 1.30
Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis. J Cell Biol (2004) 1.30
Diverse epigenetic strategies interact to control epidermal differentiation. Nat Cell Biol (2012) 1.29
Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions. J Invest Dermatol (2004) 1.27
Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt. J Cell Sci (2004) 1.22
Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin. Stem Cells (2008) 1.22
Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate. Proc Natl Acad Sci U S A (2010) 1.22
Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier. J Cell Biol (2007) 1.22
What is the point of large-scale collections of human induced pluripotent stem cells? Nat Biotechnol (2013) 1.20
Epidermal label-retaining cells: background and recent applications. J Investig Dermatol Symp Proc (2004) 1.20
Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol (2008) 1.19
A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control. J Cell Biol (2003) 1.18
A year in the life of eLife. Elife (2013) 1.14
Role of LIM kinases in normal and psoriatic human epidermis. Mol Biol Cell (2006) 1.14
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J Invest Dermatol (2007) 1.11
Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type. Cancer Res (2007) 1.09
Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture. J Cell Sci (2007) 1.08
Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation. Dev Biol (2010) 1.06
Human skin aging is associated with reduced expression of the stem cell markers beta1 integrin and MCSP. J Invest Dermatol (2009) 1.05
Regulation of interleukin-1alpha expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease. J Biol Chem (2003) 1.05
Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale. Biomaterials (2010) 1.04
The Edar subfamily in feather placode formation. Dev Biol (2007) 1.04
Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells. Development (2013) 1.04
Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol (2013) 1.03
Enhanced Edar signalling has pleiotropic effects on craniofacial and cutaneous glands. PLoS One (2009) 1.02
Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane. J Cell Biol (2004) 1.02
Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation. EMBO Mol Med (2010) 1.02
A stem cell gene expression profile of human squamous cell carcinomas. Cancer Lett (2008) 1.01
Interaction of periplakin and envoplakin with intermediate filaments. J Cell Sci (2002) 1.01
Necl2 regulates epidermal adhesion and wound repair. Development (2009) 1.01
Different consequences of beta1 integrin deletion in neonatal and adult mouse epidermis reveal a context-dependent role of integrins in regulating proliferation, differentiation, and intercellular communication. J Invest Dermatol (2005) 1.01
Expression of Notch pathway genes in mammalian epidermis and modulation by beta-catenin. Dev Dyn (2007) 0.99
FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. Cancer Res (2012) 0.97
c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis. Cell Rep (2013) 0.97
An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors. Cancer Res (2009) 0.96
Genome-wide SNP scan of pooled DNA reveals nonsense mutation in FGF20 in the scaleless line of featherless chickens. BMC Genomics (2012) 0.95
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1. Development (2010) 0.93
Kazrin regulates keratinocyte cytoskeletal networks, intercellular junctions and differentiation. J Cell Sci (2008) 0.93
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development. J Pathol (2013) 0.92
β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition. J Pathol (2012) 0.92
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors. Proc Natl Acad Sci U S A (2014) 0.91
KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules. J Cell Sci (2009) 0.91
Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer. Cancer Lett (2009) 0.91
Suprabasal alpha 5 beta1 integrin expression stimulates formation of epidermal squamous cell carcinomas without disrupting TGFbeta signaling or inducing spindle cell tumors. Mol Carcinog (2005) 0.89
PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation. Cell Res (2009) 0.88
Molecular and therapeutic characterization of anti-ectodysplasin A receptor (EDAR) agonist monoclonal antibodies. J Biol Chem (2011) 0.88
Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid and Notch signalling. PLoS One (2012) 0.88
HAN11 binds mDia1 and controls GLI1 transcriptional activity. J Dermatol Sci (2006) 0.88
Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation. PLoS One (2011) 0.88
Non-profit publishing: open access and the end of copyright transfer. J Cell Sci (2004) 0.88
Advancing research. Elife (2014) 0.88
Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells. Proc Natl Acad Sci U S A (2013) 0.87