Published in Biochemistry on June 11, 2002
Protein phosphorylation and signal transduction in cardiac thin filaments. J Biol Chem (2011) 1.23
Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation. J Biol Chem (2015) 0.89
High-yield expression of isotopically labeled peptides for use in NMR studies. Protein Sci (2003) 0.88
Characterization of protein-protein interactions critical for poliovirus replication: analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase. J Virol (2007) 0.88
Efficient expression of isotopically labeled peptides for high resolution NMR studies: application to the Cdc42/Rac binding domains of virulent kinases in Candida albicans. J Biomol NMR (2003) 0.85
Ca(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filament sliding. Arch Biochem Biophys (2014) 0.84
Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility. Arch Biochem Biophys (2016) 0.82
Gene regulation, alternative splicing, and posttranslational modification of troponin subunits in cardiac development and adaptation: a focused review. Front Physiol (2014) 0.82
Restrictive Cardiomyopathy Troponin I R145W Mutation Does Not Perturb Myofilament Length-dependent Activation in Human Cardiac Sarcomeres. J Biol Chem (2016) 0.78
Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation. J Phys Chem B (2016) 0.76
Using lanthanide ions to align troponin complexes in solution: order of lanthanide occupancy in cardiac troponin C. Protein Sci (2004) 0.75
HMDB: the Human Metabolome Database. Nucleic Acids Res (2007) 13.38
VADAR: a web server for quantitative evaluation of protein structure quality. Nucleic Acids Res (2003) 3.95
Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. Anal Chem (2007) 2.15
DNA binding: a novel function of Pseudomonas aeruginosa type IV pili. J Bacteriol (2005) 1.64
Structural based insights into the role of troponin in cardiac muscle pathophysiology. J Muscle Res Cell Motil (2005) 1.53
Structural and functional analysis of the Na+/H+ exchanger. Biochem J (2007) 1.40
A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA. Nucleic Acids Res (2009) 1.34
The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions. Biochemistry (2002) 1.33
Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein. Proc Natl Acad Sci U S A (2002) 1.25
An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscle. J Mol Biol (2006) 1.25
Smartnotebook: a semi-automated approach to protein sequential NMR resonance assignments. J Biomol NMR (2003) 1.21
Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil. J Biol Chem (2002) 1.19
In situ orientations of protein domains: troponin C in skeletal muscle fibers. Mol Cell (2003) 1.17
Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation. Biochemistry (2012) 1.11
Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies. J Mol Biol (2007) 1.11
Dynamics of the C-terminal region of TnI in the troponin complex in solution. Biophys J (2006) 1.10
Cold survival in freeze-intolerant insects: the structure and function of beta-helical antifreeze proteins. Eur J Biochem (2004) 1.09
Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate. J Biol Chem (2009) 1.08
Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate. J Biol Chem (2007) 1.06
Internal pH indicators for biomolecular NMR. J Biomol NMR (2008) 1.05
NMR structure of a bifunctional rhodamine labeled N-domain of troponin C complexed with the regulatory "switch" peptide from troponin I: implications for in situ fluorescence studies in muscle fibers. Biochemistry (2003) 1.02
Interaction of cardiac troponin with cardiotonic drugs: a structural perspective. Biochem Biophys Res Commun (2007) 1.01
Backbone dynamics of SDF-1alpha determined by NMR: interpretation in the presence of monomer-dimer equilibrium. Protein Sci (2006) 1.01
A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex. J Mol Cell Cardiol (2010) 1.00
Metabolomic profiling of asthma: diagnostic utility of urine nuclear magnetic resonance spectroscopy. J Allergy Clin Immunol (2011) 0.98
Spruce budworm antifreeze protein: changes in structure and dynamics at low temperature. J Mol Biol (2003) 0.96
Performance of medical students in a nontraditional rural clinical program, 1998-99 through 2003-04. Acad Med (2006) 0.96
Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy. Eur Biophys J (2002) 0.96
Identification of the ice-binding face of antifreeze protein from Tenebrio molitor. FEBS Lett (2002) 0.96
The binding of W7, an inhibitor of striated muscle contraction, to cardiac troponin C. Biochemistry (2005) 0.95
The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Biochemistry (2008) 0.93
Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2005) 0.93
Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex. Biochemistry (2008) 0.92
The role of electrostatics in the interaction of the inhibitory region of troponin I with troponin C. Biochemistry (2005) 0.91
NMR structure of CXCR3 binding chemokine CXCL11 (ITAC). Protein Sci (2004) 0.91
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration. Am J Physiol Endocrinol Metab (2011) 0.89
Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C. Biochemistry (2003) 0.89
NMR solution structure of a highly stable de novo heterodimeric coiled-coil. Biopolymers (2004) 0.89
Metabolomic biomarkers in a model of asthma exacerbation: urine nuclear magnetic resonance. Am J Respir Crit Care Med (2008) 0.89
Structural and functional characterization of transmembrane segment VII of the Na+/H+ exchanger isoform 1. J Biol Chem (2006) 0.88
High-yield expression of isotopically labeled peptides for use in NMR studies. Protein Sci (2003) 0.88
Differential stability of the bovine prion protein upon urea unfolding. Protein Sci (2009) 0.88
Enhancing the activity of a beta-helical antifreeze protein by the engineered addition of coils. Biochemistry (2004) 0.88
Calcium-dependent changes in the flexibility of the regulatory domain of troponin C in the troponin complex. J Biol Chem (2005) 0.88
Structure and dynamics of a beta-helical antifreeze protein. Biochemistry (2002) 0.87
1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy. J Proteome Res (2013) 0.87
Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting. J Proteome Res (2010) 0.87
Toward protein structure in situ: comparison of two bifunctional rhodamine adducts of troponin C. Biophys J (2007) 0.87
Structure determination by NMR. Isotope labeling. Methods Mol Biol (2002) 0.86
Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction. J Mol Cell Cardiol (2010) 0.86
Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Sci (2005) 0.86
Structure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I. J Biol Chem (2003) 0.86
Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir. J Am Chem Soc (2011) 0.86
The metabolomics of asthma: novel diagnostic potential. Chest (2012) 0.84
Is there nascent structure in the intrinsically disordered region of troponin I? Proteins (2011) 0.84
Structural and functional characterization of transmembrane segment IX of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2008) 0.84
Visualizing the principal component of ¹H, ¹⁵N-HSQC NMR spectral changes that reflect protein structural or functional properties: application to troponin C. J Biomol NMR (2011) 0.84
Interaction of cardiac troponin C with calmodulin antagonist [corrected] W7 in the presence of three functional regions of cardiac troponin I. Biochemistry (2006) 0.84
Structural and functional insights into the cardiac Na⁺/H⁺ exchanger. J Mol Cell Cardiol (2012) 0.83
Structure of the inhibitor W7 bound to the regulatory domain of cardiac troponin C. Biochemistry (2009) 0.83
Pulling the calcium trigger. Nat Struct Biol (2003) 0.83
Relative and regional stabilities of the hamster, mouse, rabbit, and bovine prion proteins toward urea unfolding assessed by nuclear magnetic resonance and circular dichroism spectroscopies. Biochemistry (2011) 0.83
Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2010) 0.82
Lipid-bound structure of an apolipoprotein E-derived peptide. J Biol Chem (2003) 0.82
Structural and functional analysis of transmembrane XI of the NHE1 isoform of the Na+/H+ exchanger. J Biol Chem (2009) 0.82
Isoform-specific variation in the intrinsic disorder of troponin I. Proteins (2008) 0.81
Unmasking ligand binding motifs: identification of a chemokine receptor motif by NMR studies of antagonist peptides. J Mol Biol (2003) 0.81
Effect of temperature and the F27W mutation on the Ca2+ activated structural transition of trout cardiac troponin C. Biochemistry (2003) 0.81
Freezing of a fish antifreeze protein results in amyloid fibril formation. Biophys J (2003) 0.80
The role of side chain conformational flexibility in surface recognition by Tenebrio molitor antifreeze protein. Protein Sci (2003) 0.80
Strategies for dealing with conformational sampling in structural calculations of flexible or kinked transmembrane peptides. Biochem Cell Biol (2006) 0.80
Structure of trans-resveratrol in complex with the cardiac regulatory protein troponin C. Biochemistry (2011) 0.80
Structural analysis of the Na+/H+ exchanger isoform 1 (NHE1) using the divide and conquer approach. Biochem Cell Biol (2011) 0.80
Interaction between the regulatory domain of cardiac troponin C and the acidosis-resistant cardiac troponin I A162H. Cardiovasc Res (2012) 0.79
Versatile cardiac troponin chimera for muscle protein structural biology and drug discovery. ACS Chem Biol (2014) 0.79
Structural and functional analysis of critical amino acids in TMVI of the NHE1 isoform of the Na+/H+ exchanger. Biochim Biophys Acta (2011) 0.79
Disposition and dynamics: interdomain orientations in troponin. Adv Exp Med Biol (2007) 0.79
Characterization of threonine side chain dynamics in an antifreeze protein using natural abundance 13C NMR spectroscopy. J Biomol NMR (2004) 0.79
Application of NMR spectroscopy in metabolomics. J Biomol NMR (2011) 0.79
Elucidation of isoform-dependent pH sensitivity of troponin i by NMR spectroscopy. J Biol Chem (2011) 0.79
NMR structure and dynamics of a receptor-active apolipoprotein E peptide. J Biol Chem (2002) 0.79
A PagP fusion protein system for the expression of intrinsically disordered proteins in Escherichia coli. Protein Expr Purif (2012) 0.78
Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides. BMC Struct Biol (2007) 0.78
Effect of temperature on the structure of trout troponin C. Biochemistry (2004) 0.78
Optimizing oriented planar-supported lipid samples for solid-state protein NMR. Biophys J (2005) 0.78
Structural and functional analysis of extracellular loop 2 of the Na(+)/H(+) exchanger. Biochim Biophys Acta (2009) 0.78
Expression of Saccharomyces cerevisiae Sdh3p and Sdh4p paralogs results in catalytically active succinate dehydrogenase isoenzymes. J Biol Chem (2012) 0.78