Published in Annu Rev Biochem on November 09, 2001
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci U S A (2003) 4.89
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62
What a difference a decade makes: insights into translesion DNA synthesis. Proc Natl Acad Sci U S A (2007) 3.32
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res (2008) 3.15
A semi-synthetic organism with an expanded genetic alphabet. Nature (2014) 2.70
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J (2003) 2.69
Structure of a sliding clamp on DNA. Cell (2008) 2.42
Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line. EMBO J (2003) 2.42
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. EMBO J (2009) 2.37
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. EMBO J (2004) 2.14
SOS-induced DNA polymerases enhance long-term survival and evolutionary fitness. Proc Natl Acad Sci U S A (2002) 2.12
The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature (2008) 2.08
High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J (2004) 2.07
Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase. Proc Natl Acad Sci U S A (2007) 2.06
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Proc Natl Acad Sci U S A (2002) 1.95
The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase. Proc Natl Acad Sci U S A (2006) 1.92
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli. Mol Microbiol (2003) 1.84
Deciphering cellular states of innate tumor drug responses. Genome Biol (2006) 1.83
Checkpoint activation regulates mutagenic translesion synthesis. Genes Dev (2003) 1.81
Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. Genetics (2004) 1.76
Adaptive mutation in Escherichia coli. J Bacteriol (2004) 1.75
In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR. BMC Clin Pathol (2004) 1.71
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. Proc Natl Acad Sci U S A (2008) 1.70
Genetic composition of the Bacillus subtilis SOS system. J Bacteriol (2005) 1.64
Directed evolution of ionizing radiation resistance in Escherichia coli. J Bacteriol (2009) 1.60
An analogy between the evolution of drug resistance in bacterial communities and malignant tissues. Nat Rev Cancer (2011) 1.58
Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases. Proc Natl Acad Sci U S A (2005) 1.58
Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1. Nucleic Acids Res (2005) 1.56
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc Natl Acad Sci U S A (2005) 1.53
Y-family DNA polymerases respond to DNA damage-independent inhibition of replication fork progression. EMBO J (2006) 1.53
UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB. Mol Cell (2007) 1.51
Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations. PLoS Genet (2006) 1.50
Defining the position of the switches between replicative and bypass DNA polymerases. EMBO J (2004) 1.44
An error-prone family Y DNA polymerase (DinB homolog from Sulfolobus solfataricus) uses a 'steric gate' residue for discrimination against ribonucleotides. Nucleic Acids Res (2003) 1.44
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair. EMBO J (2003) 1.42
A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV. J Am Chem Soc (2007) 1.42
Recruitment of host functions suggests a repair pathway for late steps in group II intron retrohoming. Genes Dev (2005) 1.41
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. DNA Repair (Amst) (2007) 1.39
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chem Res Toxicol (2009) 1.38
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2002) 1.36
Single-molecule DNA repair in live bacteria. Proc Natl Acad Sci U S A (2013) 1.35
A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp. J Biol Chem (2008) 1.34
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Proc Natl Acad Sci U S A (2007) 1.33
Translesion DNA polymerases. Cold Spring Harb Perspect Biol (2013) 1.33
High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds. Proc Natl Acad Sci U S A (2003) 1.32
Human DNA polymerase iota protects cells against oxidative stress. EMBO J (2008) 1.31
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2003) 1.29
Stress responses and genetic variation in bacteria. Mutat Res (2005) 1.29
Exploring the role of large conformational changes in the fidelity of DNA polymerase beta. Proteins (2008) 1.29
Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery. Cell Cycle (2009) 1.28
Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde. Proc Natl Acad Sci U S A (2003) 1.25
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Trends Biochem Sci (2008) 1.24
Development of tRNA synthetases and connection to genetic code and disease. Protein Sci (2008) 1.23
An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response. Proc Natl Acad Sci U S A (2007) 1.22
DNA polymerase POLQ and cellular defense against DNA damage. DNA Repair (Amst) (2012) 1.21
CpG dinucleotides and the mutation rate of non-CpG DNA. Genome Res (2008) 1.19
Adaptive translation as a mechanism of stress response and adaptation. Annu Rev Genet (2013) 1.17
Replication through an abasic DNA lesion: structural basis for adenine selectivity. EMBO J (2010) 1.16
Role of Escherichia coli DNA polymerase IV in in vivo replication fidelity. J Bacteriol (2004) 1.15
Estimation of the spontaneous mutation rate per nucleotide site in a Drosophila melanogaster full-sib family. Genetics (2013) 1.13
Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. J Bacteriol (2006) 1.13
The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination. Biochemistry (2006) 1.13
Evaluating evolutionary models of stress-induced mutagenesis in bacteria. Nat Rev Genet (2013) 1.12
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Chem Res Toxicol (2008) 1.12
Transcriptional mutagenesis: causes and involvement in tumour development. Nat Rev Cancer (2011) 1.12
DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation. Ann N Y Acad Sci (2005) 1.11
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. J Biol Chem (2008) 1.10
Central role of the Holliday junction helicase RuvAB in vlsE recombination and infectivity of Borrelia burgdorferi. PLoS Pathog (2009) 1.09
Translesion synthesis of 7,8-dihydro-8-oxo-2'-deoxyguanosine by DNA polymerase eta in vivo. Mutat Res (2008) 1.09
A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V. Crit Rev Biochem Mol Biol (2010) 1.08
A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase. Proc Natl Acad Sci U S A (2009) 1.08
Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. BMC Biol (2004) 1.08
Error-prone DNA polymerase IV is regulated by the heat shock chaperone GroE in Escherichia coli. J Bacteriol (2005) 1.07
Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. Nucleic Acids Res (2004) 1.07
Essential roles for imuA'- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2010) 1.07
DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair. FEMS Microbiol Rev (2012) 1.06
Mutator phenotype resulting from DNA polymerase IV overproduction in Escherichia coli: preferential mutagenesis on the lagging strand. J Bacteriol (2005) 1.06
A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks. Nucleic Acids Res (2013) 1.05
Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis. Biochemistry (2008) 1.05
Transcriptional modulator NusA interacts with translesion DNA polymerases in Escherichia coli. J Bacteriol (2008) 1.05
Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA. Proc Natl Acad Sci U S A (2011) 1.04
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. J Biol Chem (2008) 1.03
Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance. DNA Repair (Amst) (2008) 1.03
Prechemistry versus preorganization in DNA replication fidelity. Proteins (2011) 1.02
Translesion DNA polymerases and cancer. Front Genet (2012) 1.01
Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putida. J Bacteriol (2007) 1.01
Translesion DNA synthesis and mutagenesis in prokaryotes. Cold Spring Harb Perspect Biol (2013) 1.01
Polyphosphate kinase regulates error-prone replication by DNA polymerase IV in Escherichia coli. Mol Microbiol (2005) 1.00
Role of Escherichia coli DNA polymerase I in chromosomal DNA replication fidelity. Mol Microbiol (2009) 1.00
NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η. Biochemistry (2012) 1.00
Involvement of error-prone DNA polymerase IV in stationary-phase mutagenesis in Pseudomonas putida. J Bacteriol (2004) 1.00
Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota. Nucleic Acids Res (2002) 1.00
The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase. Biochemistry (2009) 1.00
Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli. J Bacteriol (2006) 0.99
Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis. J Bacteriol (2010) 0.99
The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Nucleic Acids Res (2008) 0.98
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. EMBO J (2010) 0.98
An underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis. Proc Natl Acad Sci U S A (2015) 0.96
Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases. Nucleic Acids Res (2010) 0.96
Pilin antigenic variation occurs independently of the RecBCD pathway in Neisseria gonorrhoeae. J Bacteriol (2009) 0.96