Published in DNA Repair (Amst) on October 24, 2007
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev (2012) 3.42
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res (2008) 3.15
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature (2015) 2.04
Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. DNA Repair (Amst) (2008) 2.01
DNA interstrand crosslink repair in mammalian cells: step by step. Crit Rev Biochem Mol Biol (2010) 1.82
Low-fidelity DNA synthesis by human DNA polymerase theta. Nucleic Acids Res (2008) 1.65
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Proc Natl Acad Sci U S A (2010) 1.48
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ. Nat Struct Mol Biol (2015) 1.39
Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro. Nucleic Acids Res (2009) 1.34
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ. PLoS Genet (2014) 1.33
Translesion DNA polymerases. Cold Spring Harb Perspect Biol (2013) 1.33
Human DNA polymerase θ grasps the primer terminus to mediate DNA repair. Nat Struct Mol Biol (2015) 1.27
DNA polymerase POLQ and cellular defense against DNA damage. DNA Repair (Amst) (2012) 1.21
How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat Struct Mol Biol (2015) 1.17
Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. J Mol Biol (2010) 1.12
Translesion DNA synthesis and mutagenesis in eukaryotes. Cold Spring Harb Perspect Biol (2013) 1.09
Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links. Biochemistry (2009) 1.06
Promiscuous DNA synthesis by human DNA polymerase θ. Nucleic Acids Res (2011) 1.02
DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients. Oncogenesis (2012) 1.00
DNA polymerases nu and theta are required for efficient immunoglobulin V gene diversification in chicken. J Cell Biol (2010) 0.96
Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer. Antioxid Redox Signal (2012) 0.89
Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure (2015) 0.84
Translesion DNA synthesis in the context of cancer research. Cancer Cell Int (2011) 0.82
DNA polymerase θ (POLQ), double-strand break repair, and cancer. DNA Repair (Amst) (2016) 0.81
Linking DNA polymerase theta structure and function in health and disease. Cell Mol Life Sci (2015) 0.81
Response to "Mutation frequency vs. mutation patterns: a comparison of the results in spleen and Peyer's patches" DNA Repair (Amst) (2008) 0.80
A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study. BMC Cancer (2014) 0.76
DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotides. Nucleic Acids Res (2016) 0.76
DNA Polymerase θ: A Unique Multifunctional End-Joining Machine. Genes (Basel) (2016) 0.76
Single-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites. Breast Cancer Res Treat (2014) 0.75
DNA polymerases in the mitochondria: A critical review of the evidence. Front Biosci (Landmark Ed) (2017) 0.75
Expression and Structural Analyses of Human DNA Polymerase θ (POLQ). Methods Enzymol (2017) 0.75
Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Nature (2000) 5.48
Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Annu Rev Biochem (2001) 4.47
Eukaryotic DNA polymerases. Annu Rev Biochem (2001) 3.86
Mechanisms of accurate translesion synthesis by human DNA polymerase eta. EMBO J (2000) 3.46
Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst) (2007) 3.27
poliota, a remarkably error-prone human DNA polymerase. Genes Dev (2000) 3.08
Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. Genes Dev (2000) 2.38
Role of DNA polymerase eta in the bypass of a (6-4) TT photoproduct. Mol Cell Biol (2001) 2.23
High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J (2004) 2.07
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Nucleic Acids Res (2003) 1.76
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J (2005) 1.76
Phenotype-based identification of mouse chromosome instability mutants. Genetics (2003) 1.74
DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers. Int J Cancer (2004) 1.72
Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment). J Biol Chem (1999) 1.71
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Biochemistry (2002) 1.71
The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm. Mol Cell Biol (2004) 1.68
Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr Opin Genet Dev (2004) 1.61
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc Natl Acad Sci U S A (2005) 1.53
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. J Biol Chem (2007) 1.44
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Proc Natl Acad Sci U S A (2006) 1.40
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. J Biol Chem (2004) 1.37
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Mol Cell Biol (2006) 1.34
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2003) 1.29
Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes. DNA Repair (Amst) (2006) 1.27
Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells. Genes Cells (2006) 1.04
Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota. DNA Repair (Amst) (2003) 1.03
DNA polymerases eta and iota. Adv Protein Chem (2004) 1.02
poliota-dependent lesion bypass in vitro. Mutat Res (2002) 0.98
DNA polymerases and cancer. Nat Rev Cancer (2011) 3.05
ERCC1 and non-small-cell lung cancer. N Engl J Med (2007) 2.22
High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J (2004) 2.07
Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue. Cancer Res (2009) 2.03
DNA polymerase zeta (pol zeta) in higher eukaryotes. Cell Res (2008) 2.02
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Mol Cell (2006) 1.79
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Nucleic Acids Res (2003) 1.76
Low-fidelity DNA synthesis by human DNA polymerase theta. Nucleic Acids Res (2008) 1.65
Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. Cancer Res (2006) 1.60
DNA repair: from molecular mechanism to human disease. DNA Repair (Amst) (2006) 1.56
POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. J Biol Chem (2003) 1.53
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J Biol Chem (2006) 1.49
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Proc Natl Acad Sci U S A (2010) 1.48
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. J Biol Chem (2007) 1.44
DDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA. J Biol Chem (2005) 1.38
A human DNA helicase homologous to the DNA cross-link sensitivity protein Mus308. J Biol Chem (2001) 1.36
Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines. Int J Cancer (2004) 1.34
Definition of a short region of XPG necessary for TFIIH interaction and stable recruitment to sites of UV damage. Mol Cell Biol (2004) 1.31
XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells. DNA Repair (Amst) (2006) 1.25
DNA polymerase POLQ and cellular defense against DNA damage. DNA Repair (Amst) (2012) 1.21
Polymorphisms in the human XPD (ERCC2) gene, DNA repair capacity and cancer susceptibility: an appraisal. DNA Repair (Amst) (2005) 1.16
A unique error signature for human DNA polymerase nu. DNA Repair (Amst) (2006) 1.16
DDB complexities. DNA Repair (Amst) (2003) 1.16
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis. Cancer Res (2010) 1.15
Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. J Mol Biol (2010) 1.12
DNA polymerases and somatic hypermutation of immunoglobulin genes. EMBO Rep (2005) 1.12
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Chem Res Toxicol (2010) 1.12
DNA polymerase zeta is required for proliferation of normal mammalian cells. Nucleic Acids Res (2012) 1.05
Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Radiat Res (2009) 1.03
Elevation of XPA protein level in testis tumor cells without increasing resistance to cisplatin or UV radiation. Mol Carcinog (2008) 1.00
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Nucleic Acids Res (2010) 1.00
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses. Proc Natl Acad Sci U S A (2013) 0.97
Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs. Nat Commun (2013) 0.89
Bypass specialists operate together. EMBO J (2009) 0.88
Salicylanilide inhibitors of Toxoplasma gondii. J Med Chem (2012) 0.87
Assaying for the dual incisions of nucleotide excision repair using DNA with a lesion at a specific site. Methods Mol Biol (2006) 0.86
Combining (1)H NMR spectroscopy and chemometrics to identify heparin samples that may possess dermatan sulfate (DS) impurities or oversulfated chondroitin sulfate (OSCS) contaminants. J Pharm Biomed Anal (2010) 0.84
Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases. Chem Res Toxicol (2012) 0.81
Determination of galactosamine impurities in heparin samples by multivariate regression analysis of their (1)H NMR spectra. Anal Bioanal Chem (2010) 0.81
New insights into the combined Cockayne/xeroderma pigmentosum complex: human XPG protein can function in transcription factor stability. Mol Cell (2007) 0.81
Identification of heparin samples that contain impurities or contaminants by chemometric pattern recognition analysis of proton NMR spectral data. Anal Bioanal Chem (2011) 0.78
Repair synthesis assay for nucleotide excision repair activity using fractionated cell extracts and UV-damaged plasmid DNA. Methods Mol Biol (2006) 0.77
Class modeling analysis of heparin 1H NMR spectral data using the soft independent modeling of class analogy and unequal class modeling techniques. Anal Chem (2010) 0.77
Identification of Nitazoxanide as a Group I Metabotropic Glutamate Receptor Negative Modulator for the Treatment of Neuropathic Pain: An In Silico Drug Repositioning Study. Pharm Res (2015) 0.76
Optimisation of the superplastic forming of a dental implant for bone augmentation using finite element simulations. Dent Mater (2004) 0.75