Published in J Cell Sci on July 15, 2002
Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma. Ann Neurol (2005) 5.89
Phylogenetic analysis of Sec7-domain-containing Arf nucleotide exchangers. Mol Biol Cell (2004) 1.66
ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages. J Cell Biol (2003) 1.51
Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants. PLoS Genet (2007) 1.47
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep (2004) 1.37
The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein Arf. BMC Genomics (2005) 1.29
Molecular determinants of the interaction between coxsackievirus protein 3A and guanine nucleotide exchange factor GBF1. J Virol (2007) 1.25
Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes. Mol Biol Cell (2003) 1.18
Arf6 and phosphoinositol-4-phosphate-5-kinase activities permit bypass of the Rac1 requirement for beta1 integrin-mediated bacterial uptake. J Exp Med (2003) 1.08
EFA6, exchange factor for ARF6, regulates the actin cytoskeleton and associated tight junction in response to E-cadherin engagement. Mol Biol Cell (2003) 1.07
USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly. EMBO J (2010) 1.01
Arf6 guanine nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth. J Biol Chem (2014) 0.99
Phosphatidylinositol-4-phosphate 5-kinase and GEP100/Brag2 protein mediate antiangiogenic signaling by semaphorin 3E-plexin-D1 through Arf6 protein. J Biol Chem (2011) 0.98
Endocytic and recycling endosomes modulate cell shape changes and tissue behaviour during morphogenesis in Drosophila. PLoS One (2011) 0.92
Coxiella burnetii Nine Mile II proteins modulate gene expression of monocytic host cells during infection. BMC Microbiol (2010) 0.90
Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis. EMBO J (2012) 0.85
EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway. J Biol Chem (2008) 0.84
EFA6 controls Arf1 and Arf6 activation through a negative feedback loop. Proc Natl Acad Sci U S A (2014) 0.82
Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6). J Biol Chem (2014) 0.79
Arf6 exchange factor EFA6 and endophilin directly interact at the plasma membrane to control clathrin-mediated endocytosis. Proc Natl Acad Sci U S A (2014) 0.77
Which Way In? The RalF Arf-GEF Orchestrates Rickettsia Host Cell Invasion. PLoS Pathog (2015) 0.76
Ultrastructural Localization of Endogenous Exchange Factor for ARF6 in Adrenocortical Cells In Situ of Mice. Acta Histochem Cytochem (2016) 0.75
Regulators and Effectors of Arf GTPases in Neutrophils. J Immunol Res (2015) 0.75
Regulation of Microtubule Dynamics in Axon Regeneration: Insights from C. elegans. F1000Res (2016) 0.75
ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol (2006) 7.75
Force mapping in epithelial cell migration. Proc Natl Acad Sci U S A (2005) 5.08
Inducible antibacterial defense system in C. elegans. Curr Biol (2002) 4.42
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. J Cell Sci (2009) 2.94
ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles. Curr Biol (2009) 2.82
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39
Gene expression profiling identifies molecular subtypes of inflammatory breast cancer. Cancer Res (2005) 2.26
Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene (2004) 2.09
Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila. Nature (2003) 2.06
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc Natl Acad Sci U S A (2011) 1.98
Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides. PLoS Pathog (2008) 1.97
RalB mobilizes the exocyst to drive cell migration. Mol Cell Biol (2006) 1.91
Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy. J Clin Endocrinol Metab (2004) 1.91
A bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility. PLoS Biol (2010) 1.90
Distinct and complementary information provided by use of tissue and DNA microarrays in the study of breast tumor markers. Am J Pathol (2002) 1.89
Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J Cell Biol (2005) 1.81
Endocytic traffic in animal cell cytokinesis. Curr Opin Cell Biol (2008) 1.80
Molecular characterisation and phylogenetic analysis of Chronic bee paralysis virus, a honey bee virus. Virus Res (2008) 1.72
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics. Nat Cell Biol (2005) 1.67
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
Gene expression profiling for molecular characterization of inflammatory breast cancer and prediction of response to chemotherapy. Cancer Res (2004) 1.61
Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade. Cell Host Microbe (2009) 1.60
Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes. Development (2007) 1.57
MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7. Curr Biol (2008) 1.55
The Salmonella effector protein PipB2 is a linker for kinesin-1. Proc Natl Acad Sci U S A (2006) 1.54
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. Curr Biol (2009) 1.52
ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages. J Cell Biol (2003) 1.51
Comprehensive analysis of GST-pi expression in B-cell lymphomas: Correlation with histological subtypes and survival. Leuk Lymphoma (2008) 1.44
The GDP-bound form of Arf6 is located at the plasma membrane. J Cell Sci (2004) 1.41
HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses. Mol Biol Cell (2004) 1.38
Cdc42 localization and cell polarity depend on membrane traffic. J Cell Biol (2010) 1.38
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep (2004) 1.37
The small G-protein Arf6GTP recruits the AP-2 adaptor complex to membranes. J Biol Chem (2005) 1.37
Gene expression profiles of poor-prognosis primary breast cancer correlate with survival. Hum Mol Genet (2002) 1.37
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res (2010) 1.30
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J Cell Biol (2013) 1.28
Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes. EMBO J (2007) 1.24
Signaling and membrane dynamics during phagocytosis: many roads lead to the phagos(R)ome. Curr Opin Cell Biol (2004) 1.24
ARF6 GTPase controls bacterial invasion by actin remodelling. J Cell Sci (2005) 1.22
A role for mammalian diaphanous-related formins in complement receptor (CR3)-mediated phagocytosis in macrophages. Curr Biol (2005) 1.21
Transcriptional profiling reveals coordinated up-regulation of oxidative metabolism genes in thyroid oncocytic tumors. J Clin Endocrinol Metab (2004) 1.19
Spontaneous contractility-mediated cortical flow generates cell migration in three-dimensional environments. Biophys J (2011) 1.10
XNP-1/ATR-X acts with RB, HP1 and the NuRD complex during larval development in C. elegans. Dev Biol (2005) 1.10
Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease. Blood (2003) 1.09
Small lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis. Blood (2003) 1.09
ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion. Eur J Cell Biol (2012) 1.08
HDAC6 is required for invadopodia activity and invasion by breast tumor cells. Eur J Cell Biol (2010) 1.07
The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4. EMBO J (2009) 1.07
Identification of new classes among acute myelogenous leukaemias with normal karyotype using gene expression profiling. Oncogene (2004) 1.07
Decoupling of activation and effector binding underlies ARF6 priming of fast endocytic recycling. Curr Biol (2011) 1.07
EFA6, exchange factor for ARF6, regulates the actin cytoskeleton and associated tight junction in response to E-cadherin engagement. Mol Biol Cell (2003) 1.07
Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy. Circ Res (2009) 1.06
The Syk tyrosine kinase localizes to the centrosomes and negatively affects mitotic progression. Cancer Res (2005) 1.05
Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport. J Biol Chem (2006) 1.04
αTAT1 catalyses microtubule acetylation at clathrin-coated pits. Nature (2013) 1.03
USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly. EMBO J (2010) 1.01
MADGene: retrieval and processing of gene identifier lists for the analysis of heterogeneous microarray datasets. Bioinformatics (2011) 1.01
Selective Rac1 inhibition in dendritic cells diminishes apoptotic cell uptake and cross-presentation in vivo. Blood (2004) 1.01
The pleckstrin homology domain of the Arf6-specific exchange factor EFA6 localizes to the plasma membrane by interacting with phosphatidylinositol 4,5-bisphosphate and F-actin. J Biol Chem (2008) 1.01
EFA6A enhances glioma cell invasion through ADP ribosylation factor 6/extracellular signal-regulated kinase signaling. Cancer Res (2006) 1.01
ARF1-mediated actin polymerization produces movement of artificial vesicles. Proc Natl Acad Sci U S A (2007) 1.00
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis. PLoS Pathog (2011) 0.99
Cell polarity during motile processes: keeping on track with the exocyst complex. Biochem J (2011) 0.99
Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions. BMC Genomics (2009) 0.99
V-ATPase: a potential pH sensor. Nat Cell Biol (2006) 0.96
Nutritional programming in the rat is linked to long-lasting changes in nutrient sensing and energy homeostasis in the hypothalamus. PLoS One (2010) 0.95
ARF6, PI3-kinase and host cell actin cytoskeleton in Toxoplasma gondii cell invasion. Biochem Biophys Res Commun (2008) 0.94
Proteasome-mediated degradation of Rac1-GTP during epithelial cell scattering. Mol Biol Cell (2006) 0.93
Prognosis of breast cancer and gene expression profiling using DNA arrays. Ann N Y Acad Sci (2002) 0.93
Breast cancer revisited using DNA array-based gene expression profiling. Int J Cancer (2003) 0.93
Immune response and mitochondrial metabolism are commonly deregulated in DMD and aging skeletal muscle. PLoS One (2011) 0.92
Androgen-induced masculinization in rainbow trout results in a marked dysregulation of early gonadal gene expression profiles. BMC Genomics (2007) 0.92
Control of MT1-MMP transport by atypical PKC during breast-cancer progression. Proc Natl Acad Sci U S A (2014) 0.91
AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis. Mol Biol Cell (2007) 0.91
Gene profiling reveals specific oncogenic mechanisms and signaling pathways in oncocytic and papillary thyroid carcinoma. Oncogene (2005) 0.91
Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins. Hum Mol Genet (2009) 0.90
Fbx8 makes Arf6 refractory to function via ubiquitination. Mol Biol Cell (2007) 0.90
High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies. PLoS One (2011) 0.89
Genome-wide analysis of host mRNA translation during hepatitis C virus infection. J Virol (2013) 0.89
Expression profiling of rainbow trout testis development identifies evolutionary conserved genes involved in spermatogenesis. BMC Genomics (2009) 0.88
Endosome positioning during cytokinesis. Biochem Soc Trans (2008) 0.88
Arf6 negatively controls the rapid recycling of the β2 adrenergic receptor. J Cell Sci (2012) 0.87
PGC-1-related coactivator modulates mitochondrial-nuclear crosstalk through endogenous nitric oxide in a cellular model of oncocytic thyroid tumours. PLoS One (2009) 0.87
Identification of master genes involved in liver key functions through transcriptomics and epigenomics of methyl donor deficiency in rat: relevance to nonalcoholic liver disease. Mol Nutr Food Res (2014) 0.86
Molecular risk stratification in advanced heart failure patients. J Cell Mol Med (2009) 0.85
DNA arrays in clinical oncology: promises and challenges. Lab Invest (2003) 0.85
[ARHGAP10, a novel RhoGAP at the cross-road between ARF1 and Cdc42 pathways, regulates Arp2/3 complex and actin dynamics on Golgi membranes]. Med Sci (Paris) (2005) 0.84
EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway. J Biol Chem (2008) 0.84
Meta-analysis of muscle transcriptome data using the MADMuscle database reveals biologically relevant gene patterns. BMC Genomics (2011) 0.83
Expression profiling of candidate genes during ovary-to-testis trans-differentiation in rainbow trout masculinized by androgens. Gen Comp Endocrinol (2008) 0.82
Expression profiling of prospero in the Drosophila larval chemosensory organ: Between growth and outgrowth. BMC Genomics (2010) 0.81
Gene expression profiling of human melanoma cell lines with distinct metastatic potential identifies new progression markers. Anticancer Res (2007) 0.81