David I Smith

Author PubWeight™ 99.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors. Oncogene 2002 5.40
2 Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation. Proc Natl Acad Sci U S A 2005 3.16
3 Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet 2011 3.16
4 Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon. Clin Cancer Res 2005 2.98
5 A role for common fragile site induction in amplification of human oncogenes. Cancer Cell 2002 2.63
6 Alterations in the common fragile site gene Parkin in ovarian and other cancers. Oncogene 2003 2.44
7 Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer. J Biol Chem 2003 2.40
8 Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy. Clin Cancer Res 2005 2.29
9 Malignant pheochromocytoma: current status and initiatives for future progress. Endocr Relat Cancer 2004 2.20
10 Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002 2.16
11 3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer. BMC Genomics 2009 2.12
12 Long, abundantly expressed non-coding transcripts are altered in cancer. Hum Mol Genet 2007 2.00
13 Common fragile sites are preferential targets for HPV16 integrations in cervical tumors. Oncogene 2003 2.00
14 Mutations in CHEK2 associated with prostate cancer risk. Am J Hum Genet 2003 1.96
15 Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas. Blood 2012 1.96
16 hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling. Gastroenterology 2004 1.95
17 Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing. Blood 2010 1.90
18 Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations. PLoS One 2010 1.85
19 HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma. Oncogene 2004 1.82
20 Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women. Int J Cancer 2009 1.68
21 AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer. Genes Chromosomes Cancer 2005 1.58
22 Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes. Cancer Res 2004 1.56
23 MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci 2003 1.54
24 A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer. Oncogene 2004 1.47
25 FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq. Bioinformatics 2011 1.41
26 High detection rates of colorectal neoplasia by stool DNA testing with a novel digital melt curve assay. Gastroenterology 2008 1.34
27 Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray. Int J Cancer 2006 1.32
28 Human TopBP1 ensures genome integrity during normal S phase. Mol Cell Biol 2005 1.31
29 Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization. Cancer Res 2002 1.29
30 Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer. Oncogene 2005 1.24
31 Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines. Gynecol Oncol 2005 1.24
32 The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1. Genes Chromosomes Cancer 2002 1.22
33 LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation. RNA Biol 2011 1.21
34 Characterization of FRA6E and its potential role in autosomal recessive juvenile parkinsonism and ovarian cancer. Genes Chromosomes Cancer 2003 1.21
35 Identification of long stress-induced non-coding transcripts that have altered expression in cancer. Genomics 2010 1.17
36 Preferential integration of human papillomavirus type 18 near the c-myc locus in cervical carcinoma. Oncogene 2003 1.13
37 Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis. Oncogene 2005 1.12
38 Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer. Clin Cancer Res 2003 1.12
39 Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines. Am J Hum Genet 2010 1.10
40 Dysregulated microRNAs in the pathogenesis and progression of cervical neoplasm. Cell Cycle 2012 1.06
41 Parkin gene alterations in hepatocellular carcinoma. Genes Chromosomes Cancer 2004 1.05
42 Evidence that instability within the FRA3B region extends four megabases. Oncogene 2002 0.98
43 The role of viral integration in the development of cervical cancer. Cancer Genet Cytogenet 2005 0.96
44 Psychological distress (depression and anxiety) in people with head and neck cancers. Med J Aust 2010 0.96
45 Adalimumab treatment for pyoderma gangrenosum. Arch Dermatol 2007 0.96
46 Very large common fragile site genes and their potential role in cancer development. Cell Mol Life Sci 2014 0.96
47 Induction of tumorigenesis and metastasis by the murine orthologue of tumor protein D52. Mol Cancer Res 2007 0.95
48 Genome-wide characterization of transcriptional patterns in high and low antibody responders to rubella vaccination. PLoS One 2013 0.95
49 Transcriptional profiling by sequencing of oropharyngeal cancer. Mayo Clin Proc 2012 0.94
50 Human papillomavirus-associated oropharyngeal squamous cell carcinomas: primary tumor burden and survival in surgical patients. Ann Otol Rhinol Laryngol 2009 0.94
51 Characterization of the common fragile site FRA9E and its potential role in ovarian cancer. Oncogene 2003 0.94
52 Host genetic polymorphism analysis in cervical cancer. Clin Chem 2002 0.93
53 Relationship between FRA11F and 11q13 gene amplification in oral cancer. Genes Chromosomes Cancer 2007 0.93
54 Molecular characterization of endometrial cancer: a correlative study assessing microsatellite instability, MLH1 hypermethylation, DNA mismatch repair protein expression, and PTEN, PIK3CA, KRAS, and BRAF mutation analysis. Int J Gynecol Pathol 2012 0.92
55 Next-generation sequencing: a transformative tool for vaccinology. Expert Rev Vaccines 2009 0.88
56 Vitiligo after the resolution of psoriatic plaques during treatment with adalimumab. J Am Acad Dermatol 2008 0.88
57 Adalimumab for treatment of cutaneous sarcoidosis. Arch Dermatol 2006 0.88
58 Successful treatment of mucous membrane pemphigoid with etanercept in 3 patients. Arch Dermatol 2006 0.87
59 Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases. Prog Brain Res 2004 0.86
60 Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13. Cancer Genet Cytogenet 2004 0.86
61 Disabled-1 is a large common fragile site gene, inactivated in multiple cancers. Genes Chromosomes Cancer 2008 0.84
62 A selected group of large common fragile site genes have decreased expression in oropharyngeal squamous cell carcinomas. Genes Chromosomes Cancer 2014 0.84
63 Identification of submicroscopic genetic changes and precise breakpoint mapping in myelofibrosis using high resolution mate-pair sequencing. Am J Hematol 2013 0.81
64 Off-label uses of biologic agents in dermatology: a 2006 update. Semin Cutan Med Surg 2006 0.80
65 0.1% tacrolimus ointment in the treatment of discoid lupus erythematosus. Arch Dermatol 2005 0.80
66 Assembly intermediates in polyketide biosynthesis: enantioselective syntheses of beta-hydroxycarbonyl compounds. Org Biomol Chem 2005 0.80
67 Linking expression of FOXM1, CEP55 and HELLS to tumorigenesis in oropharyngeal squamous cell carcinoma. Laryngoscope 2011 0.79
68 Human Papillomavirus and the Development of Different Cancers. Cytogenet Genome Res 2017 0.78
69 Prevention of youth suicide: how well informed are the potential gatekeepers of adolescents in distress? Suicide Life Threat Behav 2002 0.78
70 Expression profiles of viral responsive genes in oral and oropharyngeal cancers. Eur J Cancer 2010 0.78
71 Human papillomavirus in oropharyngeal squamous cell carcinoma: assessing virus presence in normal tissue and activity in cervical metastasis. Laryngoscope 2012 0.77
72 Human papillomavirus and oropharyngeal cancer. N Engl J Med 2007 0.76
73 Alefacept for alopecia areata. Arch Dermatol 2005 0.76
74 Role of the Common Fragile Sites in Cancers with a Human Papillomavirus Etiology. Cytogenet Genome Res 2017 0.75
75 A single-center, open-label, prospective pilot study of subcutaneous efalizumab for oral erosive lichen planus. J Drugs Dermatol 2007 0.75
76 Transcriptional profiling reveals that several common fragile-site genes are downregulated in ovarian cancer. Genes Chromosomes Cancer 2002 0.75
77 Efalizumab-induced subacute cutaneous lupus erythematosus. J Am Acad Dermatol 2006 0.75
78 T-lymphocyte clonality in benign lichenoid keratoses. J Cutan Pathol 2002 0.75
79 Adolescent girls' responses to warning signs of abuse in romantic relationships: implications for youth-targeted relationship violence prevention. J Interpers Violence 2009 0.75
80 Search for chromosome rearrangements: new approaches toward discovery of novel translocations in head and neck squamous cell carcinoma. Head Neck 2012 0.75
81 DNA microchips to identify molecular signatures in cervical cancers. Methods Mol Biol 2007 0.75