PubRank

Kota V Ramana

Author PubWeight™ 58.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. Endocr Rev 2005 2.42
2 Aldose reductase inhibition prevents endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci 2007 1.61
3 Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells. Cancer Res 2006 1.27
4 Contribution of aldose reductase to diabetic hyperproliferation of vascular smooth muscle cells. Diabetes 2006 1.13
5 Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice. PLoS One 2009 1.11
6 Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation. Carcinogenesis 2008 1.10
7 Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. Chem Biol Interact 2011 1.09
8 Focus on molecules: nuclear factor-kappaB. Exp Eye Res 2008 1.08
9 Prevention of posterior capsular opacification through aldose reductase inhibition. Invest Ophthalmol Vis Sci 2008 1.07
10 Nitric oxide prevents aldose reductase activation and sorbitol accumulation during diabetes. Diabetes 2002 1.06
11 Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells. Exp Eye Res 2007 1.03
12 Aldose reductase regulates high glucose-induced ectodomain shedding of tumor necrosis factor (TNF)-alpha via protein kinase C-delta and TNF-alpha converting enzyme in vascular smooth muscle cells. Endocrinology 2008 1.01
13 Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells. Invest Ophthalmol Vis Sci 2006 1.01
14 Regulation of NF-κB-induced inflammatory signaling by lipid peroxidation-derived aldehydes. Oxid Med Cell Longev 2013 1.00
15 Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett 2007 0.98
16 Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells. J Biol Chem 2011 0.97
17 Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1. Invest Ophthalmol Vis Sci 2009 0.96
18 Aldose reductase inhibition suppresses the expression of Th2 cytokines and airway inflammation in ovalbumin-induced asthma in mice. J Immunol 2009 0.95
19 Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo. Angiogenesis 2011 0.95
20 Measurement and identification of S-glutathiolated proteins. Methods Enzymol 2010 0.94
21 Anti-inflammatory effect of aldose reductase inhibition in murine polymicrobial sepsis. Cytokine 2009 0.93
22 Aldose reductase deficiency protects sugar-induced lens opacification in rats. Chem Biol Interact 2011 0.93
23 Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages. Free Radic Biol Med 2011 0.92
24 Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells. Toxicol Appl Pharmacol 2007 0.92
25 Post-translational protein modification by carotenoid cleavage products. Biofactors 2011 0.91
26 Aldose reductase inhibition prevents metaplasia of airway epithelial cells. PLoS One 2010 0.89
27 Structure of a glutathione conjugate bound to the active site of aldose reductase. Proteins 2006 0.89
28 Antidiabetic drug metformin suppresses endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci 2012 0.88
29 Inhibition of aldose reductase prevents colon cancer metastasis. Carcinogenesis 2011 0.88
30 Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes. J Toxicol Environ Health A 2009 0.88
31 Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway. Exp Eye Res 2009 0.87
32 4-Hydroxynonenal in the pathogenesis and progression of human diseases. Curr Med Chem 2014 0.87
33 Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice. PLoS One 2013 0.87
34 Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci 2011 0.87
35 L-Arginine prevents metabolic effects of high glucose in diabetic mice. FEBS Lett 2008 0.87
36 Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle. Endocrinology 2010 0.86
37 Synthesis, quantification, characterization, and signaling properties of glutathionyl conjugates of enals. Methods Enzymol 2010 0.85
38 Prevention of endotoxin-induced uveitis in rats by plant sterol guggulsterone. Invest Ophthalmol Vis Sci 2010 0.84
39 Endotoxin-induced uveitis in rodents. Methods Mol Biol 2013 0.83
40 A potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseases. Expert Opin Investig Drugs 2012 0.83
41 Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin. Invest Ophthalmol Vis Sci 2002 0.83
42 Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a. Antioxid Redox Signal 2012 0.83
43 Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Free Radic Biol Med 2011 0.83
44 Retracted Piceatannol suppresses endotoxin-induced ocular inflammation in rats. Int Immunopharmacol 2013 0.83
45 Aldose reductase inhibition: emerging drug target for the treatment of cardiovascular complications. Recent Pat Cardiovasc Drug Discov 2010 0.82
46 Aldose reductase deficiency protects from autoimmune- and endotoxin-induced uveitis in mice. Invest Ophthalmol Vis Sci 2011 0.82
47 Role of aldose reductase in TNF-alpha-induced apoptosis of vascular endothelial cells. Chem Biol Interact 2003 0.82
48 Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages. Free Radic Biol Med 2010 0.82
49 Targeting aldose reductase for the treatment of cancer. Curr Cancer Drug Targets 2011 0.81
50 Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cells. Curr Eye Res 2009 0.80
51 Aldose reductase inhibition prevents lipopolysaccharide-induced glucose uptake and glucose transporter 3 expression in RAW264.7 macrophages. Int J Biochem Cell Biol 2010 0.80
52 Amelioration of experimental autoimmune uveoretinitis by aldose reductase inhibition in Lewis rats. Invest Ophthalmol Vis Sci 2011 0.80
53 Inhibition of aldose reductase attenuates endotoxin signals in human non-pigmented ciliary epithelial cells. Exp Eye Res 2010 0.79
54 Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression. Eur J Cancer 2013 0.79
55 Focus on molecules: lutein. Exp Eye Res 2011 0.78
56 Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors. Free Radic Biol Med 2013 0.78
57 Aldose reductase prevents aldehyde toxicity in cultured human lens epithelial cells. Exp Eye Res 2006 0.78
58 Aldose reductase inhibition suppresses airway inflammation. Chem Biol Interact 2011 0.77
59 Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma. Respir Res 2011 0.77
60 Aldose reductase inhibition for the treatment of asthma. Expert Rev Clin Immunol 2010 0.77
61 Regulation of lens aldose reductase activity by nitric oxide. Exp Eye Res 2005 0.77
62 Prevention of VEGF-induced growth and tube formation in human retinal endothelial cells by aldose reductase inhibition. J Diabetes Complications 2012 0.76
63 Prevention of allergic rhinitis by aldose reductase inhibition in a murine model. Inflamm Allergy Drug Targets 2013 0.75
64 Regulation of aldose reductase and the polyol pathway activity by nitric oxide. Chem Biol Interact 2003 0.75