Published in Exp Eye Res on February 04, 2010
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Prevention of VEGF-induced growth and tube formation in human retinal endothelial cells by aldose reductase inhibition. J Diabetes Complications (2012) 0.76
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Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells. J Biol Chem (2002) 1.51
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Activation of nuclear factor-kappaB by hyperglycemia in vascular smooth muscle cells is regulated by aldose reductase. Diabetes (2004) 1.33
Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells. Cancer Res (2006) 1.27
Requirement of aldose reductase for the hyperglycemic activation of protein kinase C and formation of diacylglycerol in vascular smooth muscle cells. Diabetes (2005) 1.26
Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation (2006) 1.17
Aldose reductase mediates cytotoxic signals of hyperglycemia and TNF-alpha in human lens epithelial cells. FASEB J (2002) 1.15
Contribution of aldose reductase to diabetic hyperproliferation of vascular smooth muscle cells. Diabetes (2006) 1.13
Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice. PLoS One (2009) 1.11
Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation. Carcinogenesis (2008) 1.10
Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. Chem Biol Interact (2011) 1.09
Inhibition of aldose reductase attenuates TNF-alpha-induced expression of adhesion molecules in endothelial cells. FASEB J (2004) 1.09
Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells. Mol Cancer Ther (2010) 1.09
Focus on molecules: nuclear factor-kappaB. Exp Eye Res (2008) 1.08
Prevention of posterior capsular opacification through aldose reductase inhibition. Invest Ophthalmol Vis Sci (2008) 1.07
Nitric oxide prevents aldose reductase activation and sorbitol accumulation during diabetes. Diabetes (2002) 1.06
Mediation of aldose reductase in lipopolysaccharide-induced inflammatory signals in mouse peritoneal macrophages. Cytokine (2006) 1.05
Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells. Exp Eye Res (2007) 1.03
Aldose reductase regulates high glucose-induced ectodomain shedding of tumor necrosis factor (TNF)-alpha via protein kinase C-delta and TNF-alpha converting enzyme in vascular smooth muscle cells. Endocrinology (2008) 1.01
Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells. Invest Ophthalmol Vis Sci (2006) 1.01
Aldose reductase: a novel therapeutic target for inflammatory pathologies. Int J Biochem Cell Biol (2009) 1.00
Regulation of NF-κB-induced inflammatory signaling by lipid peroxidation-derived aldehydes. Oxid Med Cell Longev (2013) 1.00
Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages. Free Radic Biol Med (2007) 1.00
Aldose reductase regulates TNF-alpha-induced cell signaling and apoptosis in vascular endothelial cells. FEBS Lett (2004) 0.99
Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett (2007) 0.98
Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth. Endocrinology (2007) 0.96
Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1. Invest Ophthalmol Vis Sci (2009) 0.96
Aldose reductase inhibition suppresses the expression of Th2 cytokines and airway inflammation in ovalbumin-induced asthma in mice. J Immunol (2009) 0.95
Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo. Angiogenesis (2011) 0.95
Measurement and identification of S-glutathiolated proteins. Methods Enzymol (2010) 0.94
Aldose reductase deficiency protects sugar-induced lens opacification in rats. Chem Biol Interact (2011) 0.93
Anti-inflammatory effect of aldose reductase inhibition in murine polymicrobial sepsis. Cytokine (2009) 0.93
Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages. Free Radic Biol Med (2011) 0.92
Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells. Toxicol Appl Pharmacol (2007) 0.92
Post-translational protein modification by carotenoid cleavage products. Biofactors (2011) 0.91
Metabolism of lipid derived aldehyde, 4-hydroxynonenal in human lens epithelial cells and rat lens. Invest Ophthalmol Vis Sci (2003) 0.90
Structure of a glutathione conjugate bound to the active site of aldose reductase. Proteins (2006) 0.89
Aldose reductase inhibition prevents metaplasia of airway epithelial cells. PLoS One (2010) 0.89
Antidiabetic drug metformin suppresses endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci (2012) 0.88
Nitric oxide regulates the polyol pathway of glucose metabolism in vascular smooth muscle cells. FASEB J (2003) 0.88
Inhibition of aldose reductase prevents colon cancer metastasis. Carcinogenesis (2011) 0.88
Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes. J Toxicol Environ Health A (2009) 0.88
4-Hydroxynonenal in the pathogenesis and progression of human diseases. Curr Med Chem (2014) 0.87
Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice. PLoS One (2013) 0.87
Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway. Exp Eye Res (2009) 0.87
L-Arginine prevents metabolic effects of high glucose in diabetic mice. FEBS Lett (2008) 0.87
Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci (2011) 0.87
Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle. Endocrinology (2010) 0.86
Studies on the genotoxicity of endosulfan in different tissues of fresh water fish Mystus vittatus using the comet assay. Arch Environ Contam Toxicol (2007) 0.86
Acute toxicity bioassays of mercuric chloride and malathion on air-breathing fish Channa punctatus (Bloch). Ecotoxicol Environ Saf (2005) 0.85
Synthesis, quantification, characterization, and signaling properties of glutathionyl conjugates of enals. Methods Enzymol (2010) 0.85
Investigation of the genotoxicity of malathion to freshwater teleost fish Channa punctatus (Bloch) using the micronucleus test and comet assay. Arch Environ Contam Toxicol (2009) 0.85
Prevention of endotoxin-induced uveitis in rats by plant sterol guggulsterone. Invest Ophthalmol Vis Sci (2010) 0.84
Endotoxin-induced uveitis in rodents. Methods Mol Biol (2013) 0.83
Aldose reductase catalyzes reduction of the lipid peroxidation product 4-oxonon-2-enal. Chem Res Toxicol (2003) 0.83
A potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseases. Expert Opin Investig Drugs (2012) 0.83
Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Free Radic Biol Med (2011) 0.83
Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a. Antioxid Redox Signal (2012) 0.83
Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin. Invest Ophthalmol Vis Sci (2002) 0.83
Retracted Piceatannol suppresses endotoxin-induced ocular inflammation in rats. Int Immunopharmacol (2013) 0.83
Genotoxicity evaluation of acute doses of endosulfan to freshwater teleost Channa punctatus (Bloch) by alkaline single-cell gel electrophoresis. Ecotoxicol Environ Saf (2005) 0.82
Aldose reductase mediates the mitogenic signals of cytokines. Chem Biol Interact (2003) 0.82