Autocrine production of IFN-gamma by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMID 12097414)

Published in J Immunol on July 15, 2002

Authors

Carla E Carvalho-Pinto1, María I García, Mario Mellado, J Miguel Rodríguez-Frade, Juan Martín-Caballero, Juana Flores, Carlos Martínez-A, Dimitrios Balomenos

Author Affiliations

1: Department of Immunology and Oncology, Centro Nacional de Biotecnología/Consejo Superior de Investigaciones Cientificas, Cantoblanco, Madrid, Spain.

Articles citing this

Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. J Clin Invest (2009) 1.41

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis. J Am Soc Nephrol (2010) 1.09

Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon-gamma dysregulation. Arthritis Rheum (2008) 1.06

Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis: getting to know the unknown. Clin Dev Immunol (2012) 1.05

CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB. J Am Soc Nephrol (2009) 1.01

The MRL/lpr mouse strain as a model for neuropsychiatric systemic lupus erythematosus. J Biomed Biotechnol (2011) 0.97

Pathogenic and protective role of macrophages in kidney disease. Am J Physiol Renal Physiol (2013) 0.97

The role of cytokine in the lupus nephritis. J Biomed Biotechnol (2011) 0.90

Interplay between Wnt/β-catenin signaling and HIV: virologic and biologic consequences in the CNS. J Neuroimmune Pharmacol (2012) 0.89

Constraint-based network model of pathogen-immune system interactions. J R Soc Interface (2008) 0.89

Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity. J Autoimmun (2012) 0.87

Cytokine-induced monocyte characteristics in SLE. J Biomed Biotechnol (2010) 0.82

Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury. Br J Pharmacol (2007) 0.80

Fetal bovine serum xenoproteins modulate human monocyte adhesion and protein release on biomaterials in vitro. Acta Biomater (2010) 0.79

DHMEQ, a novel nuclear factor-kappaB inhibitor, induces selective depletion of alloreactive or phytohaemagglutinin-stimulated peripheral blood mononuclear cells, decreases production of T helper type 1 cytokines, and blocks maturation of dendritic cells. Immunology (2008) 0.79

Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production. Sci Rep (2015) 0.77

CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production. J Pathol (2015) 0.75

Articles by these authors

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally. EMBO J (2002) 4.17

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A (2007) 3.61

T cell costimulation by chemokine receptors. Nat Immunol (2005) 3.00

Pathogens: raft hijackers. Nat Rev Immunol (2003) 2.63

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. J Exp Med (2012) 2.35

Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds. Immunity (2007) 2.29

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus. Nat Med (2005) 2.28

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. Dev Biol (2005) 2.10

Identification of amino acid residues crucial for chemokine receptor dimerization. Nat Immunol (2004) 2.09

APRIL modulates B and T cell immunity. J Clin Invest (2002) 2.07

Statins inhibit HIV-1 infection by down-regulating Rho activity. J Exp Med (2004) 2.00

Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation. Eur J Immunol (2008) 1.97

DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production. Blood (2006) 1.89

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing. Immunity (2004) 1.73

Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis. J Cell Biol (2004) 1.72

A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. J Exp Med (2007) 1.71

Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. Genes Dev (2004) 1.71

Filamin-A regulates actin-dependent clustering of HIV receptors. Nat Cell Biol (2007) 1.71

The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. J Clin Invest (2002) 1.55

Cohesin component dynamics during meiotic prophase I in mammalian oocytes. Chromosome Res (2004) 1.43

CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. J Clin Invest (2003) 1.41

Tumour-suppression activity of the proapoptotic regulator Par4. EMBO Rep (2005) 1.36

PTEN regulates motility but not directionality during leukocyte chemotaxis. J Cell Sci (2004) 1.35

Control of T helper 2 cell function and allergic airway inflammation by PKCzeta. Proc Natl Acad Sci U S A (2005) 1.34

APRIL promotes B-1 cell-associated neoplasm. Cancer Cell (2004) 1.34

Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface. J Cell Sci (2004) 1.34

CCR6 regulates EAE pathogenesis by controlling regulatory CD4+ T-cell recruitment to target tissues. Eur J Immunol (2009) 1.34

Increased p53 activity does not accelerate telomere-driven ageing. EMBO Rep (2006) 1.30

Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle. Proc Natl Acad Sci U S A (2010) 1.29

Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains. J Exp Med (2002) 1.28

CCR5 expression influences the progression of human breast cancer in a p53-dependent manner. J Exp Med (2003) 1.25

GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway. EMBO J (2002) 1.25

Chemokines integrate JAK/STAT and G-protein pathways during chemotaxis and calcium flux responses. Eur J Immunol (2003) 1.23

Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. Blood (2010) 1.22

Statins induce regulatory T cell recruitment via a CCL1 dependent pathway. J Immunol (2008) 1.22

Inhibition of programmed cell death impairs in vitro vascular-like structure formation and reduces in vivo angiogenesis. FASEB J (2002) 1.21

Functional inactivation of CXC chemokine receptor 4-mediated responses through SOCS3 up-regulation. J Exp Med (2002) 1.21

Absence of CCR8 does not impair the response to ovalbumin-induced allergic airway disease. J Immunol (2003) 1.19

CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses. Blood (2005) 1.19

Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice. EMBO Rep (2004) 1.18

Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms. J Clin Invest (2005) 1.18

CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2/CCR2-dependent gene expression profile. J Immunol (2014) 1.18

From rafts to crafts: membrane asymmetry in moving cells. Trends Immunol (2003) 1.16

T cell activation in vivo targets diacylglycerol kinase alpha to the membrane: a novel mechanism for Ras attenuation. J Immunol (2003) 1.15

p21CIP1/WAF1 controls proliferation of activated/memory T cells and affects homeostasis and memory T cell responses. J Immunol (2007) 1.13

Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in non-obese diabetic mice. Eur J Immunol (2004) 1.12

Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement. J Cell Biol (2007) 1.12

CCR6 has a non-redundant role in the development of inflammatory bowel disease. Eur J Immunol (2003) 1.12

MacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells. Mol Cell Biol (2012) 1.11

Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs. J Cell Biol (2004) 1.11

The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma. Blood (2005) 1.09

Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells. Neoplasia (2009) 1.09

SOCS up-regulation mobilizes autologous stem cells through CXCR4 blockade. Blood (2006) 1.09

Notch activation stimulates migration of breast cancer cells and promotes tumor growth. Breast Cancer Res (2013) 1.08

Class IB-phosphatidylinositol 3-kinase (PI3K) deficiency ameliorates IA-PI3K-induced systemic lupus but not T cell invasion. J Immunol (2006) 1.07

Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio. J Immunol (2003) 1.06

Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice. Mol Cell Biol (2004) 1.05

CXCL13/CXCR5 signaling enhances BCR-triggered B-cell activation by shaping cell dynamics. Blood (2011) 1.04

Degradation of cellular mRNA is a general early apoptosis-induced event. FASEB J (2002) 1.04

c-Myc is essential for hematopoietic stem cell differentiation and regulates Lin(-)Sca-1(+)c-Kit(-) cell generation through p21. Exp Hematol (2007) 1.03

Calcium influx through receptor-operated channel induces mitochondria-triggered paraptotic cell death. J Biol Chem (2003) 1.03

CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathway. Blood (2002) 1.03

The chemokine stromal cell-derived factor-1 alpha modulates alpha 4 beta 7 integrin-mediated lymphocyte adhesion to mucosal addressin cell adhesion molecule-1 and fibronectin. J Immunol (2002) 1.00

Analysis of post-translational CCR8 modifications and their influence on receptor activity. J Biol Chem (2004) 0.99

CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection. Immunol Cell Biol (2010) 0.99

Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability. Proc Natl Acad Sci U S A (2007) 0.97

Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis. Chromosoma (2009) 0.96

Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity. Cancer Res (2005) 0.96

E-box-independent regulation of transcription and differentiation by MYC. Nat Cell Biol (2011) 0.95

Chemokine receptor oligomerization: functional considerations. Curr Opin Pharmacol (2009) 0.94

PI3Kgamma activation by CXCL12 regulates tumor cell adhesion and invasion. Biochem Biophys Res Commun (2009) 0.93

Chromothripsis: breakage-fusion-bridge over and over again. Cell Cycle (2013) 0.93

Combined loss of p21(waf1/cip1) and p27(kip1) enhances tumorigenesis in mice. Lab Invest (2011) 0.93

Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor. EMBO J (2003) 0.92

Cyclin-dependent kinase inhibitor p21, via its C-terminal domain, is essential for resolution of murine inflammatory arthritis. Arthritis Rheum (2012) 0.92

CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells. J Invest Dermatol (2011) 0.92

Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ. J Biol Chem (2004) 0.91

Dido3 PHD modulates cell differentiation and division. Cell Rep (2013) 0.91

Polymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts. Eur J Immunol (2005) 0.91

Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis. Biol Cell (2004) 0.91

Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. J Biol Chem (2002) 0.90

Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1). Eur J Immunol (2009) 0.90

Dynamic regulation of CXCR1 and CXCR2 homo- and heterodimers. J Immunol (2009) 0.90