Published in Biochem Biophys Res Commun on July 19, 2002
Reactive Oxygen Species Derived from NOX3 and NOX5 Drive Differentiation of Human Oligodendrocytes. Front Cell Neurosci (2016) 0.76
The Cu, Zn Superoxide Dismutase: Not Only a Dismutase Enzyme. Front Physiol (2016) 0.76
Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. N Engl J Med (2006) 4.46
The endocannabinoid system and its therapeutic exploitation. Nat Rev Drug Discov (2004) 3.47
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation. Proc Natl Acad Sci U S A (2002) 2.35
Possible endocannabinoid control of colorectal cancer growth. Gastroenterology (2003) 1.89
Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem (2010) 1.71
Cell signalling and the glutathione redox system. Biochem Pharmacol (2002) 1.68
High-affinity Zn2+ uptake system ZnuABC is required for bacterial zinc homeostasis in intracellular environments and contributes to the virulence of Salmonella enterica. Infect Immun (2007) 1.68
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Proc Natl Acad Sci U S A (2006) 1.67
Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. Mol Cell Biol (2003) 1.67
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J Pharmacol Exp Ther (2006) 1.61
Glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum. J Biol Chem (2004) 1.58
Pharmacological actions of statins: a critical appraisal in the management of cancer. Pharmacol Rev (2011) 1.44
Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells. Eur J Cancer (2013) 1.39
Mitochondrial dysfunction in neurodegenerative diseases associated with copper imbalance. Neurochem Res (2004) 1.29
Redox implications of AMPK-mediated signal transduction beyond energetic clues. J Cell Sci (2012) 1.28
Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts. J Biol Chem (2005) 1.26
Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response. J Immunol (2009) 1.25
The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits human breast cancer cell proliferation through a lipid raft-mediated mechanism. Mol Pharmacol (2006) 1.24
Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway. FASEB J (2002) 1.23
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. FASEB J (2004) 1.21
Anandamide inhibits adhesion and migration of breast cancer cells. Exp Cell Res (2005) 1.21
Role of nitric oxide synthases in Parkinson's disease: a review on the antioxidant and anti-inflammatory activity of polyphenols. Neurochem Res (2008) 1.20
Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage. J Biol Chem (2007) 1.20
The endocannabinoid signaling system in cancer. Trends Pharmacol Sci (2013) 1.20
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells. Free Radic Biol Med (2005) 1.19
Cannabinoids and cancer: pros and cons of an antitumour strategy. Br J Pharmacol (2006) 1.18
TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State. Int J Cell Biol (2012) 1.17
Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide. Cancer Res (2003) 1.17
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site. J Biol Chem (2004) 1.15
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis. FASEB J (2003) 1.15
Age-related impairment in insulin release: the essential role of β(2)-adrenergic receptor. Diabetes (2012) 1.15
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells. FASEB J (2004) 1.14
Endocannabinoids in endocrine and related tumours. Endocr Relat Cancer (2008) 1.14
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. Brain Res Bull (2003) 1.12
p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance. Antioxid Redox Signal (2012) 1.12
In skeletal muscle advanced glycation end products (AGEs) inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs. J Biol Chem (2008) 1.11
2',3'-Cyclic nucleotide 3'-phosphodiesterase: a membrane-bound, microtubule-associated protein and membrane anchor for tubulin. Proc Natl Acad Sci U S A (2002) 1.11
Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function. J Biol Chem (2002) 1.11
Proapoptotic activity of new glutathione S-transferase inhibitors. Cancer Res (2005) 1.10
Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. J Cell Physiol (2007) 1.10
Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug. J Bioenerg Biomembr (2012) 1.08
Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism. J Biol Chem (2003) 1.08
Statins and cancer in gastroenterology: new insight? Gastroenterology (2013) 1.07
Frontiers: PED/PEA-15, a multifunctional protein controlling cell survival and glucose metabolism. Am J Physiol Endocrinol Metab (2009) 1.07
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. Mol Cell Biol (2008) 1.07
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2. FASEB J (2003) 1.07
Isatin-Schiff base copper(II) complexes and their influence on cellular viability. J Inorg Biochem (2005) 1.06
Under the ROS…thiol network is the principal suspect for autophagy commitment. Autophagy (2010) 1.04
Endocannabinoid system modulation in cancer biology and therapy. Pharmacol Res (2009) 1.01
Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells. FEBS Lett (2005) 1.01
The cannabinoid CB1 receptor antagonist rimonabant stimulates 2-deoxyglucose uptake in skeletal muscle cells by regulating the expression of phosphatidylinositol-3-kinase. Mol Pharmacol (2008) 1.01
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. J Cell Physiol (2011) 1.00
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. FASEB J (2006) 1.00
Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells. J Cell Sci (2011) 1.00
Redox mechanisms involved in the selective activation of Nrf2-mediated resistance versus p53-dependent apoptosis in adenocarcinoma cells. J Biol Chem (2009) 0.99
Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease. Neurobiol Aging (2010) 0.99
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol kinase subcellular localization. J Biol Chem (2007) 0.98
Atorvastatin improves the course of ischemic acute renal failure in aging rats. J Am Soc Nephrol (2004) 0.98
p38(MAPK) and ERK1/2 dictate cell death/survival response to different pro-oxidant stimuli via p53 and Nrf2 in neuroblastoma cells SH-SY5Y. Biochem Pharmacol (2012) 0.98
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase. FEBS Lett (2004) 0.98
Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15. J Biol Chem (2004) 0.98
Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action. Mol Cell Biol (2004) 0.98
Bisphenol A in polycystic ovary syndrome and its association with liver-spleen axis. Clin Endocrinol (Oxf) (2013) 0.98
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence. J Biol Chem (2008) 0.97
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells. Diabetes (2007) 0.97
Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon. J Biol Chem (2005) 0.97
HaRas activates the NADPH oxidase complex in human neuroblastoma cells via extracellular signal-regulated kinase 1/2 pathway. J Neurochem (2004) 0.97
Concomitant BRAF(V600E) mutation and RET/PTC rearrangement is a frequent occurrence in papillary thyroid carcinoma. Thyroid (2013) 0.97
In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. Eur J Pharmacol (2004) 0.96
Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells. J Med Chem (2009) 0.96
Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems. Fundam Clin Pharmacol (2002) 0.94
Copper-dependent toxicity in SH-SY5Y neuroblastoma cells involves mitochondrial damage. Biochem Biophys Res Commun (2005) 0.93
Reactive oxygen species, Ki-Ras, and mitochondrial superoxide dismutase cooperate in nerve growth factor-induced differentiation of PC12 cells. J Biol Chem (2010) 0.92
Double-strand DNA cleavage induced by oxindole-Schiff base copper(II) complexes with potential antitumor activity. J Inorg Biochem (2008) 0.92
Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. J Biol Chem (2009) 0.92
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1. Cancer Res (2012) 0.92
Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells. FEBS Lett (2006) 0.92