PubRank

Shaun Purcell

Author PubWeight™ 390.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 85.39
2 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007 51.70
3 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
4 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
5 Genome-wide detection and characterization of positive selection in human populations. Nature 2007 17.27
6 Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet 2008 15.89
7 Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009 12.19
8 Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet 2012 12.10
9 Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet 2007 8.74
10 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
11 Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet 2006 7.49
12 Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 2013 7.44
13 Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet 2005 6.61
14 Ascertainment through family history of disease often decreases the power of family-based association studies. Behav Genet 2007 6.06
15 Synaptic, transcriptional and chromatin genes disrupted in autism. Nature 2014 5.30
16 Powerful regression-based quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet 2002 5.20
17 Genomic inflation factors under polygenic inheritance. Eur J Hum Genet 2011 4.89
18 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet 2009 4.38
19 Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes 2007 3.84
20 The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet 2008 2.79
21 Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genet 2010 2.68
22 Dissecting the phenotype in genome-wide association studies of psychiatric illness. Br J Psychiatry 2009 2.65
23 Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol 2010 2.17
24 Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2009 2.03
25 Parental monitoring moderates the importance of genetic and environmental influences on adolescent smoking. J Abnorm Psychol 2007 1.99
26 Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet 2010 1.89
27 zCall: a rare variant caller for array-based genotyping: genetics and population analysis. Bioinformatics 2012 1.87
28 Genome-wide association study of suicide attempts in mood disorder patients. Am J Psychiatry 2010 1.85
29 A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry 2009 1.84
30 Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Am J Psychiatry 2010 1.82
31 The positives, protocols, and perils of genome-wide association. Am J Med Genet B Neuropsychiatr Genet 2008 1.73
32 Changing environmental influences on substance use across development. Twin Res Hum Genet 2007 1.70
33 The Promises and Pitfalls of Genoeconomics* Annu Rev Econom 2012 1.66
34 Family-based association study of lithium-related and other candidate genes in bipolar disorder. Arch Gen Psychiatry 2008 1.53
35 Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Arch Gen Psychiatry 2007 1.53
36 Family dysfunction interacts with genes in the causation of antisocial symptoms. Behav Genet 2005 1.49
37 Domestic violence is associated with environmental suppression of IQ in young children. Dev Psychopathol 2003 1.47
38 Optimal selection strategies for QTL mapping using pooled DNA samples. Eur J Hum Genet 2002 1.45
39 Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Neuropsychopharmacology 2008 1.29
40 Pretrauma cognitive ability and risk for posttraumatic stress disorder: a twin study. Arch Gen Psychiatry 2007 1.24
41 Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study. Genet Epidemiol 2011 1.22
42 Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder. Am J Psychiatry 2010 1.16
43 Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents. Am J Med Genet B Neuropsychiatr Genet 2006 1.14
44 Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships. Hum Mol Genet 2004 1.14
45 Influence of RGS2 on anxiety-related temperament, personality, and brain function. Arch Gen Psychiatry 2008 1.10
46 Parental familial vulnerability, family environment, and their interactions as predictors of depressive symptoms in adolescents. J Am Acad Child Adolesc Psychiatry 2004 1.09
47 Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes. Genet Epidemiol 2011 1.08
48 Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample. Eur J Hum Genet 2011 1.07
49 Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities. Am J Hum Genet 2012 1.07
50 Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on executive function in schizophrenia. Schizophr Res 2007 1.07
51 Implication of a rare deletion at distal 16p11.2 in schizophrenia. JAMA Psychiatry 2013 1.05
52 Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia. Biol Psychiatry 2007 1.04
53 Multivariate genomewide linkage scan of neurocognitive traits and ADHD symptoms: suggestive linkage to 3q13. Am J Med Genet B Neuropsychiatr Genet 2008 1.03
54 Two quantitative trait loci for prepulse inhibition of startle identified on mouse chromosome 16 using chromosome substitution strains. Genetics 2005 1.00
55 Genetic differences between five European populations. Hum Hered 2010 0.98
56 Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder. Biol Psychiatry 2007 0.96
57 Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS. Hum Mol Genet 2009 0.96
58 Genome-wide association study implicates a novel RNA gene, the lincRNA AC068718.1, as a risk factor for post-traumatic stress disorder in women. Psychoneuroendocrinology 2013 0.94
59 The serotonin transporter gene as a QTL for ADHD. Am J Med Genet B Neuropsychiatr Genet 2005 0.92
60 Population differences in the International Multi-Centre ADHD Gene Project. Genet Epidemiol 2008 0.90
61 Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry 2014 0.90
62 The relationship of fatigue to mental and physical health in a community sample. Soc Psychiatry Psychiatr Epidemiol 2005 0.88
63 Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease. Hum Mutat 2006 0.88
64 Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction. PLoS One 2012 0.86
65 Identification of EFHC2 as a quantitative trait locus for fear recognition in Turner syndrome. Hum Mol Genet 2006 0.85
66 Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2011 0.84
67 Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. Am J Med Genet B Neuropsychiatr Genet 2010 0.83
68 Investigation of parent-of-origin effects in ADHD candidate genes. Am J Med Genet B Neuropsychiatr Genet 2007 0.83
69 Power calculations in genetic studies. Cold Spring Harb Protoc 2012 0.82
70 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2008 0.81
71 A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability. Am J Med Genet B Neuropsychiatr Genet 2013 0.81
72 Highly penetrant alterations of a critical region including BDNF in human psychopathology and obesity. Arch Gen Psychiatry 2012 0.80
73 Association of reading disability on chromosome 6p22 in the Afrikaner population. Am J Med Genet B Neuropsychiatr Genet 2008 0.78