Published in Development on October 04, 2006
Control of ground-state pluripotency by allelic regulation of Nanog. Nature (2012) 2.25
The function of non-coding RNAs in genomic imprinting. Development (2009) 2.21
Zinc finger protein ZFP57 requires its co-factor to recruit DNA methyltransferases and maintains DNA methylation imprint in embryonic stem cells via its transcriptional repression domain. J Biol Chem (2011) 1.88
The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing. Development (2009) 1.69
Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc Natl Acad Sci U S A (2010) 1.64
Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice. Proc Natl Acad Sci U S A (2009) 1.56
Epigenetic profiling at mouse imprinted gene clusters reveals novel epigenetic and genetic features at differentially methylated regions. Genome Res (2009) 1.52
G9a histone methyltransferase contributes to imprinting in the mouse placenta. Mol Cell Biol (2007) 1.51
Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1. Mol Cell Biol (2007) 1.40
Imprinting and epigenetic changes in the early embryo. Mamm Genome (2009) 1.40
Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer. Am J Transl Res (2012) 1.33
Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing. Genome Res (2008) 1.28
Imprinted noncoding RNAs. Mamm Genome (2008) 1.24
Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues. Heredity (Edinb) (2010) 1.22
Epigenetic regulation in mammalian preimplantation embryo development. Reprod Biol Endocrinol (2009) 1.15
Regulation of imprinted expression by macro non-coding RNAs. RNA Biol (2009) 1.11
The transcriptional status but not the imprinting control region determines allele-specific histone modifications at the imprinted H19 locus. Mol Cell Biol (2007) 1.07
Distinguishing epigenetic marks of developmental and imprinting regulation. Epigenetics Chromatin (2010) 1.04
Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status. PLoS One (2012) 1.01
A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA. Mamm Genome (2007) 0.95
Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells. Development (2011) 0.94
Identification and functional analysis of long non-coding RNAs in mouse cleavage stage embryonic development based on single cell transcriptome data. BMC Genomics (2014) 0.92
Posttranslational modifications of the histone 3 tail and their impact on the activity of histone lysine demethylases in vitro. PLoS One (2013) 0.90
Coordinated allele-specific histone acetylation at the differentially methylated regions of imprinted genes. Nucleic Acids Res (2010) 0.89
Expression of KCNQ1OT1, CDKN1C, H19, and PLAGL1 and the methylation patterns at the KvDMR1 and H19/IGF2 imprinting control regions is conserved between human and bovine. J Biomed Sci (2012) 0.83
Immature cryopreserved ovary restores puberty and fertility in mice without alteration of epigenetic marks. PLoS One (2008) 0.83
MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure. Nucleic Acids Res (2012) 0.82
An imprinted GFP insertion reveals long-range epigenetic regulation in embryonic lineages. Dev Biol (2009) 0.82
An extended domain of Kcnq1ot1 silencing revealed by an imprinted fluorescent reporter. Mol Cell Biol (2011) 0.82
Differentiation-driven nucleolar association of the mouse imprinted Kcnq1 locus. G3 (Bethesda) (2012) 0.82
Identification of 4438 novel lincRNAs involved in mouse pre-implantation embryonic development. Mol Genet Genomics (2014) 0.81
Loss of imprinting of insulin-like growth factor 2 is associated with increased risk of lymph node metastasis and gastric corpus cancer. J Exp Clin Cancer Res (2009) 0.81
Methamphetamine induces alterations in the long non-coding RNAs expression profile in the nucleus accumbens of the mouse. BMC Neurosci (2015) 0.79
Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive. Nucleic Acids Res (2015) 0.78
Establishment and functions of DNA methylation in the germline. Epigenomics (2016) 0.77
Roles of intragenic and intergenic L1s in mouse and human. PLoS One (2014) 0.77
A survey of imprinted gene expression in mouse trophoblast stem cells. G3 (Bethesda) (2015) 0.75
Identification and evolutionary analysis of long non-coding RNAs in zebra finch. BMC Genomics (2017) 0.75
Blocked transcription through KvDMR1 results in absence of methylation and gene silencing resembling Beckwith-Wiedemann syndrome. Development (2017) 0.75
Evolution and functions of long noncoding RNAs. Cell (2009) 17.54
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell (2008) 9.76
Active genes dynamically colocalize to shared sites of ongoing transcription. Nat Genet (2004) 9.57
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature (2011) 9.33
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature (2010) 8.84
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature (2007) 7.91
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell (2009) 7.39
Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell (2010) 6.88
Epigenetic reprogramming in mammals. Hum Mol Genet (2005) 6.73
Epigenetic reprogramming in mouse primordial germ cells. Mech Dev (2002) 6.67
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A (2006) 5.95
Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol (2002) 5.86
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat Commun (2011) 5.66
Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet (2004) 5.47
Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis (2003) 5.19
Epigenetic reprogramming in plant and animal development. Science (2010) 5.18
X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet (2008) 5.18
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (2012) 5.17
Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature (2002) 5.10
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem (2004) 4.86
Transient homologous chromosome pairing marks the onset of X inactivation. Science (2006) 4.45
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell (2012) 4.32
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell (2010) 4.32
Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet (2011) 4.25
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
YY1 tethers Xist RNA to the inactive X nucleation center. Cell (2011) 4.06
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet (2008) 3.89
Postmeiotic sex chromatin in the male germline of mice. Curr Biol (2006) 3.80
A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization. Mol Cell (2006) 3.67
DNA demethylation by DNA repair. Trends Genet (2009) 3.49
Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet (2004) 3.47
Intersection of the RNA interference and X-inactivation pathways. Science (2008) 3.43
Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet (2009) 3.25
X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells. Proc Natl Acad Sci U S A (2008) 3.25
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. Cell (2010) 3.18
Long noncoding RNAs: past, present, and future. Genetics (2013) 3.16
Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol (2009) 3.12
Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing. Cell (2007) 3.03
Xist RNA is a potent suppressor of hematologic cancer in mice. Cell (2013) 2.93
FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency. Cell Stem Cell (2013) 2.79
BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell (2011) 2.79
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol (2008) 2.77
Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos. Nature (2003) 2.76
Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev (2009) 2.76
The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat Cell Biol (2012) 2.73
Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. Mol Cell (2007) 2.69
Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta. Dev Biol (2002) 2.63
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature (2013) 2.63
Molecular subtypes and phenotypic expression of Beckwith-Wiedemann syndrome. Eur J Hum Genet (2005) 2.62
CTCF, a candidate trans-acting factor for X-inactivation choice. Science (2001) 2.59
Jpx RNA activates Xist by evicting CTCF. Cell (2013) 2.56
Dynamic chromatin modifications characterise the first cell cycle in mouse embryos. Dev Biol (2005) 2.51
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature (2009) 2.40
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein. Nat Genet (2007) 2.35
Xite, X-inactivation intergenic transcription elements that regulate the probability of choice. Mol Cell (2003) 2.21
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet (2008) 2.20
Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr Biol (2003) 2.14
Resourceful imprinting. Nature (2004) 2.10
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus. PLoS Genet (2008) 2.08
Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes. PLoS Biol (2007) 2.06
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol (2012) 1.94
Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci U S A (2005) 1.90
An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype. Hum Mol Genet (2003) 1.85
The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development. Mol Cell Biol (2009) 1.78
Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions. Hum Mol Genet (2003) 1.73
Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc (2012) 1.70
Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers. Philos Trans R Soc Lond B Biol Sci (2013) 1.70
The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing. Development (2009) 1.69
Higher order chromatin structure at the X-inactivation center via looping DNA. Dev Biol (2008) 1.68
Placental overgrowth in mice lacking the imprinted gene Ipl. Proc Natl Acad Sci U S A (2002) 1.67
Germline mutation in NLRP2 (NALP2) in a familial imprinting disorder (Beckwith-Wiedemann Syndrome). PLoS Genet (2009) 1.64
Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth. Proc Natl Acad Sci U S A (2011) 1.59
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development (2012) 1.55
Mice deficient in APOBEC2 and APOBEC3. Mol Cell Biol (2005) 1.55
Sitagliptin exerts an antinflammatory action. J Clin Endocrinol Metab (2012) 1.55
Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome. Proc Natl Acad Sci U S A (2010) 1.55
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nat Protoc (2013) 1.54
The importance of cysteine cathepsin proteases for placental development. J Mol Med (Berl) (2006) 1.54
X-chromosome inactivation: a hypothesis linking ontogeny and phylogeny. Nat Rev Genet (2005) 1.52
A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biol (2013) 1.50
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev (2006) 1.49
Two-step imprinted X inactivation: repeat versus genic silencing in the mouse. Mol Cell Biol (2010) 1.46
Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer. Semin Cell Dev Biol (2003) 1.44
Dnmt2-dependent methylomes lack defined DNA methylation patterns. Proc Natl Acad Sci U S A (2013) 1.43
Unique receptor repertoire in mouse uterine NK cells. J Immunol (2008) 1.41
Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain. PLoS Genet (2011) 1.37
Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. Cochrane Database Syst Rev (2009) 1.37
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. Genome Res (2012) 1.35
Sex chromosome silencing in the marsupial male germ line. Proc Natl Acad Sci U S A (2007) 1.34