Microarray-based identification of htrA, a Streptococcus pneumoniae gene that is regulated by the CiaRH two-component system and contributes to nasopharyngeal colonization.

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Published in Infect Immun on August 01, 2002

Authors

M E Sebert1, L M Palmer, M Rosenberg, J N Weiser

Author Affiliations

1: Department of Pediatrics, Children's Hospital of Philadelphia, Pennsylvania 19104, USA.

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Endocytosis in Chang liver cells. Quantitation by sucrose- 3 H uptake and inhibition by cytochalasin B. J Cell Biol (1971) 2.63

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Relationship between colonial morphology and adherence of Streptococcus pneumoniae. Infect Immun (1995) 2.50

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Structure and function of the cy control region of bacteriophage lambda. J Mol Biol (1980) 2.37

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Pentapeptide nuclear localization signal in adenovirus E1a. Mol Cell Biol (1987) 2.30

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Efficient expression of influenza virus NS1 nonstructural proteins in Escherichia coli. Proc Natl Acad Sci U S A (1983) 2.19

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Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue. J Biol Chem (1994) 2.04

The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med (1990) 2.03

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Characterization of short tandem repeats from thirty-one human telomeres. Genome Res (1997) 1.96

Functions of purified E1A protein microinjected into mammalian cells. Proc Natl Acad Sci U S A (1984) 1.92

Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro. Proc Natl Acad Sci U S A (1986) 1.90

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Differential translation efficiency explains discoordinate expression of the galactose operon. Cell (1981) 1.87

Activation of human immunodeficiency virus type 1 by DNA damage in human cells. Nature (1988) 1.85

Bacterial phosphorylcholine decreases susceptibility to the antimicrobial peptide LL-37/hCAP18 expressed in the upper respiratory tract. Infect Immun (2000) 1.84

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation. Proc Natl Acad Sci U S A (1988) 1.84

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Purification and characterization of human H-ras proteins expressed in Escherichia coli. Mol Cell Biol (1985) 1.77

Impaired nuclear transport of a human variant tRNAiMet. Nature (1982) 1.75

Inhibition of bacterial adherence to hydrocarbons and epithelial cells by emulsan. Infect Immun (1983) 1.71

Trimellitic anhydride-induced airway syndromes: clinical and immunologic studies. J Allergy Clin Immunol (1977) 1.71

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Studying promoters and terminators by gene fusion. Science (1983) 1.64

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Determination of nucleotide sequences beyond the sites of transcriptional termination. Proc Natl Acad Sci U S A (1976) 1.61

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A physical map of the human Y chromosome. Nature (2001) 1.58

T lymphocyte lines producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells. Eur J Immunol (1983) 1.58

Regulated expression at high copy number allows production of a growth-inhibitory oncogene product in Drosophila Schneider cells. Genes Dev (1989) 1.56

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Isolation and sequence determination of the 3'-terminal regions of isotopically labelled RNA molecules. Nucleic Acids Res (1974) 1.53

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Mapping of functional domains in adenovirus E1A proteins. Proc Natl Acad Sci U S A (1985) 1.53

Control of transcription termination: a rho-dependent termination site in bacteriophage lambda. J Mol Biol (1980) 1.51

Studies on the interactions of nucleotides, polynucleotides, and nucleic acids with dihydroxyboryl-substituted celluloses. Biochemistry (1972) 1.51

Nucleotide sequence surrounding a ribonuclease III processing site in bacteriophage T7 RNA. Proc Natl Acad Sci U S A (1977) 1.50

Structure of simian virus 40 recombinants that contain both host and viral DNA sequences. II. The structure of variant 1103 and its comparison to variant CVPS/1P2 (EcoRI res). J Biol Chem (1979) 1.49

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