PubRank

Janko Kos

Author PubWeight™ 74.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. J Control Release 2007 1.73
2 Cysteine cathepsins (proteases)--on the main stage of cancer? Cancer Cell 2004 1.27
3 Cystatins in immune system. J Cancer 2012 1.22
4 Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro. Exp Cell Res 2003 1.20
5 Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer. Adv Enzyme Regul 2002 1.08
6 Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells. Exp Cell Res 2006 1.05
7 Role of cysteine cathepsins in matrix degradation and cell signalling. Connect Tissue Res 2008 1.05
8 Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis. Cancer Gene Ther 2003 1.05
9 Intracellular proteolytic activity of cathepsin B is associated with capillary-like tube formation by endothelial cells in vitro. J Cell Biochem 2006 1.04
10 The role of cathepsin X in the migration and invasiveness of T lymphocytes. J Cell Sci 2008 1.01
11 High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas. Acta Neuropathol 2009 0.99
12 Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins. Immunology 2008 0.98
13 Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds. ChemMedChem 2011 0.97
14 Cystatin C as a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma. Cancer Lett 2006 0.95
15 γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways. Biochem J 2012 0.95
16 Inhibitory properties of cystatin F and its localization in U937 promonocyte cells. FEBS J 2005 0.93
17 Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells. Int J Biochem Cell Biol 2009 0.91
18 Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors. J Cancer Res Clin Oncol 2009 0.91
19 Nanoscale polymer carriers to deliver chemotherapeutic agents to tumours. Expert Opin Biol Ther 2005 0.90
20 Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAcβ1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis. J Biol Chem 2012 0.90
21 Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer. Anticancer Res 2003 0.90
22 Proteins of higher fungi--from forest to application. Trends Biotechnol 2012 0.89
23 Lysosomal enzymes, cathepsins in brain tumour invasion. J Neurooncol 2002 0.89
24 The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer. Eur J Clin Invest 2010 0.89
25 Cystatins in non-small cell lung cancer: tissue levels, localization and relation to prognosis. Oncol Rep 2006 0.89
26 Purification, characterization and cloning of a ricin B-like lectin from mushroom Clitocybe nebularis with antiproliferative activity against human leukemic T cells. Biochim Biophys Acta 2008 0.89
27 Natural killer cells as effectors of selection and differentiation of stem cells: role in resolution of inflammation. J Immunotoxicol 2014 0.88
28 Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. Cancer Detect Prev 2002 0.87
29 Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. Eur J Cell Biol 2012 0.87
30 Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness. Mol Cancer 2009 0.87
31 Cystatin incorporated in poly(lactide-co-glycolide) nanoparticles: development and fundamental studies on preservation of its activity. Eur J Pharm Sci 2004 0.87
32 Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X. J Leukoc Biol 2008 0.87
33 Stefin a and stefin B: markers for prognosis in operable squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 2007 0.87
34 Cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells. J Biol Chem 2012 0.86
35 Structural basis of trypsin inhibition and entomotoxicity of cospin, serine protease inhibitor involved in defense of Coprinopsis cinerea fruiting bodies. J Biol Chem 2011 0.85
36 DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function. J Leukoc Biol 2011 0.85
37 Cysteine cathepsins in neurological disorders. Mol Neurobiol 2013 0.85
38 Versatile loops in mycocypins inhibit three protease families. J Biol Chem 2009 0.85
39 Poly(lactide-co-glycolide) nanoparticles as a carrier system for delivering cysteine protease inhibitor cystatin into tumor cells. Exp Cell Res 2004 0.85
40 γ-1-syntrophin mediates trafficking of γ-enolase towards the plasma membrane and enhances its neurotrophic activity. Neurosignals 2011 0.84
41 Differentiation- and maturation-dependent content, localization, and secretion of cystatin C in human dendritic cells. J Leukoc Biol 2005 0.84
42 Immunonanoparticles--an effective tool to impair harmful proteolysis in invasive breast tumor cells. FEBS J 2007 0.84
43 Serum cystatin C in patients with head and neck carcinoma. Clin Chim Acta 2004 0.83
44 Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor. J Med Chem 2014 0.83
45 Microbial and fungal protease inhibitors--current and potential applications. Appl Microbiol Biotechnol 2012 0.83
46 Cathepsin X prevents an effective immune response against Helicobacter pylori infection. Eur J Cell Biol 2009 0.82
47 Cysteine cathepsins: regulators of antitumour immune response. Expert Opin Biol Ther 2006 0.82
48 Profilin 1 as a target for cathepsin X activity in tumor cells. PLoS One 2013 0.82
49 Cathepsin X in serum from patients with colorectal cancer: relation to prognosis. Radiol Oncol 2012 0.82
50 Genotoxicity of trivalent chromium in bacterial cells. Possible effects on DNA topology. Chem Res Toxicol 2002 0.82
51 Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety. PLoS One 2011 0.81
52 CNL, a ricin B-like lectin from mushroom Clitocybe nebularis, induces maturation and activation of dendritic cells via the toll-like receptor 4 pathway. Immunology 2011 0.81
53 Basidiomycete Clitocybe nebularis is rich in lectins with insecticidal activities. Appl Microbiol Biotechnol 2011 0.81
54 Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles. Nanomedicine (Lond) 2010 0.81
55 Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells. J Leukoc Biol 2011 0.80
56 Iron-regulated surface determinant B (IsdB) promotes Staphylococcus aureus adherence to and internalization by non-phagocytic human cells. Cell Microbiol 2013 0.80
57 Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives. J Med Chem 2013 0.80
58 A novel β-trefoil lectin from the parasol mushroom (Macrolepiota procera) is nematotoxic. FEBS J 2014 0.80
59 Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes. Immunology 2004 0.80
60 LFA-1 fine-tuning by cathepsin X. IUBMB Life 2011 0.79
61 Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding. Eur J Immunol 2009 0.79
62 Regulation of cathepsin B activity by 2A2 monoclonal antibody. FEBS J 2009 0.79
63 Three-dimensional invasion of macrophages is mediated by cysteine cathepsins in protrusive podosomes. Eur J Immunol 2012 0.79
64 Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X. Aging Cell 2013 0.79
65 Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms. J Biol Chem 2011 0.79
66 In vitro and in vivo characterization of temoporfin-loaded PEGylated PLGA nanoparticles for use in photodynamic therapy. Nanomedicine (Lond) 2012 0.78
67 Characterization of two novel subtilases from common bean (Phaseolus vulgaris L.) and their responses to drought. Plant Physiol Biochem 2012 0.78
68 Cathepsin S generates soluble CX3CL1 (fractalkine) in vascular smooth muscle cells. Biol Chem 2013 0.78
69 Helicobacter pylori susceptible/resistant to antibiotic eradication therapy differ in the maturation and activation of dendritic cells. Helicobacter 2013 0.78
70 Monoclonal antibody to cytokeratin VKIALEVEIATY sequence motif reduces plasminogen activation in breast tumour cells. Cancer Lett 2008 0.78
71 Levels of cathepsins S and H in pleural fluids of inflammatory and neoplastic origin. Int J Biol Markers 2009 0.78
72 Cysteine protease-mediated cytoskeleton interactions with LFA-1 promote T-cell morphological changes. Cell Motil Cytoskeleton 2009 0.78
73 Cathepsin H indirectly regulates morphogenetic protein-4 (BMP-4) in various human cell lines. Radiol Oncol 2011 0.78
74 Proteolytic profile of cysteine proteases and inhibitors determines tumor cell phenotype in squamous cell carcinoma of the head and neck. Int J Biol Markers 2011 0.78
75 Proinflammatory effects of bare and PEGylated ORMOSIL-, PLGA- and SUV-NPs on monocytes and PMNs and their modulation by f-MLP. Nanomedicine (Lond) 2011 0.77
76 Inhibition of endopeptidase and exopeptidase activity of cathepsin B impairs extracellular matrix degradation and tumour invasion. Biol Chem 2016 0.77
77 The influence of differential processing of procathepsin H on its aminopeptidase activity, secretion and subcellular localization in human cell lines. Eur J Cell Biol 2012 0.77
78 Protease inhibitors clitocypin and macrocypin are differentially expressed within basidiomycete fruiting bodies. Biochimie 2011 0.77
79 The Expression of Lysosomal Proteinases and Their Inhibitors in Breast Cancer: Possible Relationship to Prognosis of the Disease. Pathol Oncol Res 1997 0.77
80 Trypsin-specific inhibitors from the basidiomycete Clitocybe nebularis with regulatory and defensive functions. Microbiology 2009 0.77
81 Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin B. Eur J Med Chem 2011 0.77
82 C-terminal peptide of γ-enolase impairs amyloid-β-induced apoptosis through p75(NTR) signaling. Neuromolecular Med 2013 0.76
83 Serum cysteine proteases and their inhibitors in rheumatoid arthritis: relation to disease activity and radiographic progression. Clin Rheumatol 2010 0.76
84 Improved acylation method enables efficient delivery of functional palmitoylated cystatin into epithelial cells. Chem Biol Drug Des 2007 0.76
85 Mycoplasma gallisepticum and Mycoplasma synoviae express a cysteine protease CysP, which can cleave chicken IgG into Fab and Fc. Microbiology 2010 0.76
86 Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori. Radiol Oncol 2013 0.76
87 Inhibition of the growth of colorado potato beetle larvae by macrocypins, protease inhibitors from the parasol mushroom. J Agric Food Chem 2013 0.76
88 Intracellular delivery of cysteine protease inhibitor cystatin by polymeric nanoparticles. J Nanosci Nanotechnol 2006 0.76
89 Expression of stefin A is of prognostic significance in squamous cell carcinoma of the head and neck. Eur Arch Otorhinolaryngol 2013 0.75
90 Molecular dynamics to enhance structure-based virtual screening on cathepsin B. J Comput Aided Mol Des 2015 0.75
91 Clioquinol-ruthenium complex impairs tumour cell invasion by inhibiting cathepsin B activity. Dalton Trans 2016 0.75
92 Cystatin C in sera of patients with aggressive non-Hodgkin B-cell lymphoma. Med Glas (Zenica) 2011 0.75
93 A dodecapeptide deduced from cytokeratin sequence strongly enhances uPA/tPA-mediated plasminogen activation. Br J Haematol 2010 0.75
94 The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and In Vivo Activity. J Med Chem 2017 0.75
95 Molecular cloning and chimerisation of an inhibitory anti-cathepsin B antibody and its expression in Chinese hamster ovary cells. Biol Chem 2002 0.75
96 Interrelated cathepsin S-lowering and LDL subclass profile improvements induced by atorvastatin in the plasma of stable angina patients. J Atheroscler Thromb 2014 0.75