Published in Exp Hematol on July 01, 2002
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice. Genes Dev (2003) 3.58
Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis. Mol Cell Biol (2005) 2.00
Mouse models of Fanconi anemia. Mutat Res (2009) 1.49
Stem cells and aging in the hematopoietic system. Mech Ageing Dev (2008) 1.16
The Fanconi anemia pathway and ubiquitin. BMC Biochem (2007) 1.10
Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models. Dis Model Mech (2013) 1.05
Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice. Blood (2006) 1.03
CXCR4 induction in hematopoietic progenitor cells from Fanca(-/-), -c(-/-), and -d2(-/-) mice. Exp Hematol (2008) 0.96
Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia. Blood (2010) 0.95
TNF-α signaling in Fanconi anemia. Blood Cells Mol Dis (2013) 0.94
Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res (2013) 0.85
FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice. Chromosoma (2015) 0.84
Fanconi anemia A is a nucleocytoplasmic shuttling molecule required for gonadotropin-releasing hormone (GnRH) transduction of the GnRH receptor. Endocrinology (2006) 0.82
The phenotype of FancB-mutant mouse embryonic stem cells. Mutat Res (2011) 0.81
Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities. J Mol Med (Berl) (2012) 0.75
Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction. Genes Dev (2016) 0.75
Concise Review: Getting to the Core of Inherited Bone Marrow Failures. Stem Cells (2016) 0.75
Biallelic inactivation of BRCA2 in Fanconi anemia. Science (2002) 9.31
Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature (2003) 6.92
The Fanconi anaemia/BRCA pathway. Nat Rev Cancer (2003) 5.89
Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice. Nat Biotechnol (2007) 5.04
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature (2013) 4.94
S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood (2002) 4.27
Generation and regeneration of cells of the liver and pancreas. Science (2008) 4.21
Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nat Med (2004) 3.77
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice. Genes Dev (2003) 3.58
Stem cells and liver regeneration. Gastroenterology (2009) 3.40
The ploidy conveyor of mature hepatocytes as a source of genetic variation. Nature (2010) 3.27
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17
The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci U S A (2003) 2.99
AAV serotype 2 vectors preferentially integrate into active genes in mice. Nat Genet (2003) 2.81
The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell (2003) 2.71
Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci U S A (2004) 2.66
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev (2011) 2.53
Epigenomic plasticity enables human pancreatic α to β cell reprogramming. J Clin Invest (2013) 2.38
Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates. Hum Gene Ther (2004) 2.32
Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell (2012) 2.26
Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol Cell Biol (2004) 2.20
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev (2011) 2.17
Myeloid lineage progenitors give rise to vascular endothelium. Proc Natl Acad Sci U S A (2006) 2.13
An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol (2005) 2.11
Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver. J Virol (2005) 2.09
Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin. Blood (2004) 2.08
A surface on the androgen receptor that allosterically regulates coactivator binding. Proc Natl Acad Sci U S A (2007) 1.97
Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. J Clin Invest (2009) 1.95
Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab (2011) 1.89
Kinetics of liver repopulation after bone marrow transplantation. Am J Pathol (2002) 1.85
Anthracyclines induce DNA damage response-mediated protection against severe sepsis. Immunity (2013) 1.83
Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol (2006) 1.82
Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proc Natl Acad Sci U S A (2006) 1.82
Resveratrol increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol (2007) 1.81
Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero. Proc Natl Acad Sci U S A (2003) 1.79
Therapeutic liver reconstitution with murine cells isolated long after death. Gastroenterology (2010) 1.78
Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis. Cancer Cell (2008) 1.75
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med (2011) 1.74
siRNA depletion of BRCA1, but not BRCA2, causes increased genome instability in Fanconi anemia cells. DNA Repair (Amst) (2003) 1.69
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest (2004) 1.67
Surface markers for the murine oval cell response. Hepatology (2008) 1.65
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. Proc Natl Acad Sci U S A (2010) 1.64
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension (2009) 1.63
In vivo correction of murine hereditary tyrosinemia type I by phiC31 integrase-mediated gene delivery. Mol Ther (2005) 1.59
Production of pluripotent stem cells by oocyte-assisted reprogramming: joint statement with signatories. Natl Cathol Bioeth Q (2005) 1.57
Mutations in PHF6 are associated with Börjeson-Forssman-Lehmann syndrome. Nat Genet (2002) 1.57
Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice. J Clin Invest (2006) 1.54
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. J Clin Invest (2012) 1.52
Neonatal hemochromatosis: radiographical and histological signs. Liver Transpl (2005) 1.50
The Min oscillator uses MinD-dependent conformational changes in MinE to spatially regulate cytokinesis. Cell (2011) 1.49
Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. Stem Cell Res (2008) 1.45
Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm. Stem Cells (2009) 1.43
Association of JAK2 mutation status and cytogenetic abnormalities in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms. Am J Clin Pathol (2011) 1.43
Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency. Hum Mutat (2003) 1.42
Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo. Hepatology (2010) 1.41
Increased hepatic transduction with reduced systemic dissemination and proinflammatory cytokines following hydrodynamic injection of helper-dependent adenoviral vectors. Mol Ther (2005) 1.40
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition. Mol Ther (2002) 1.39
Seeking consensus: a clarification and defense of altered nuclear transfer. Hastings Cent Rep (2006) 1.39
The impact of clonal evolution on response to imatinib mesylate (STI571) in accelerated phase CML. Blood (2002) 1.39
Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology (2014) 1.32
Frequent aneuploidy among normal human hepatocytes. Gastroenterology (2011) 1.30
Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol. Blood (2010) 1.29
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data. BMC Bioinformatics (2008) 1.29
Ploidy reductions in murine fusion-derived hepatocytes. PLoS Genet (2009) 1.28
TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. Blood (2009) 1.26
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. Cancer Res (2010) 1.26
Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses. J Virol (2012) 1.24
The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate. Protein Sci (2011) 1.23
Aneuploidy as a mechanism for stress-induced liver adaptation. J Clin Invest (2012) 1.23
Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice. Cancer Res (2008) 1.22
Natural gene therapy in monozygotic twins with Fanconi anemia. Blood (2006) 1.20
Intensified platinum therapy is an ineffective strategy for improving outcome in pediatric patients with advanced hepatoblastoma. J Clin Oncol (2006) 1.20
Heterozygosity for p53 (Trp53+/-) accelerates epithelial tumor formation in fanconi anemia complementation group D2 (Fancd2) knockout mice. Cancer Res (2005) 1.17
Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology. PLoS One (2010) 1.17
Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice. J Clin Invest (2010) 1.15
Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining. Hum Mol Genet (2005) 1.15
Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proc Natl Acad Sci U S A (2010) 1.14
Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria). J Pharmacol Exp Ther (2002) 1.13
Long-term correction of ornithine transcarbamylase deficiency by WPRE-mediated overexpression using a helper-dependent adenovirus. Mol Ther (2004) 1.12
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients. Cancer Res (2005) 1.12
Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. J Biol Chem (2010) 1.11