Published in Angew Chem Int Ed Engl on January 01, 2010
Identification of epigenetic DNA modifications with a protein nanopore. Chem Commun (Camb) (2010) 1.93
Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore. Nano Lett (2010) 1.51
Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes. Nano Lett (2011) 1.42
DNA base-calling from a nanopore using a Viterbi algorithm. Biophys J (2012) 1.41
Analysis of single nucleic acid molecules with protein nanopores. Methods Enzymol (2010) 1.29
Nanopore sequencing: from imagination to reality. Clin Chem (2014) 1.23
Three decades of nanopore sequencing. Nat Biotechnol (2016) 1.21
Individual RNA base recognition in immobilized oligonucleotides using a protein nanopore. Nano Lett (2012) 1.06
DNA stretching and optimization of nucleobase recognition in enzymatic nanopore sequencing. Nanotechnology (2015) 0.98
The evolution of nanopore sequencing. Front Genet (2015) 0.91
Molecular dynamics simulations of DNA within a nanopore: arginine-phosphate tethering and a binding/sliding mechanism for translocation. Biochemistry (2011) 0.91
Temperature and electrolyte optimization of the α-hemolysin latch sensing zone for detection of base modification in double-stranded DNA. Biophys J (2014) 0.90
BROMOC-D: Brownian Dynamics/Monte-Carlo Program Suite to Study Ion and DNA Permeation in Nanopores. J Chem Theory Comput (2012) 0.90
Electrical Current Signatures of DNA Base Modifications in Single Molecules Immobilized in the α-Hemolysin Ion Channel. Isr J Chem (2013) 0.85
Slowing DNA Transport Using Graphene-DNA Interactions. Adv Funct Mater (2015) 0.84
Water Mediates Recognition of DNA Sequence via Ionic Current Blockade in a Biological Nanopore. ACS Nano (2016) 0.84
Nucleobase Recognition by Truncated α-Hemolysin Pores. ACS Nano (2015) 0.84
Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel. Chem Commun (Camb) (2012) 0.83
Detection of 3'-end RNA uridylation with a protein nanopore. ACS Nano (2013) 0.82
Differentiation of G:C vs A:T and G:C vs G:mC Base Pairs in the Latch Zone of α-Hemolysin. ACS Nano (2015) 0.79
A Protein Rotaxane Controls the Translocation of Proteins Across a ClyA Nanopore. Nano Lett (2015) 0.78
Microsecond simulations of DNA and ion transport in nanopores with novel ion-ion and ion-nucleotides effective potentials. J Comput Chem (2014) 0.77
DNA sequencing with MspA: Molecular Dynamics simulations reveal free-energy differences between sequencing and non-sequencing mutants. Sci Rep (2015) 0.76
MspA nanopore as a single-molecule tool: From sequencing to SPRNT. Methods (2016) 0.76
The Nucleotide Capture Region of Alpha Hemolysin: Insights into Nanopore Design for DNA Sequencing from Molecular Dynamics Simulations. Nanomaterials (Basel) (2015) 0.75
DNA sequence-dependent ionic currents in ultra-small solid-state nanopores. Nanoscale (2016) 0.75
Analysis of single nucleic acid molecules in micro- and nano-fluidics. Lab Chip (2016) 0.75
Characterization of individual polynucleotide molecules using a membrane channel. Proc Natl Acad Sci U S A (1996) 18.77
The potential and challenges of nanopore sequencing. Nat Biotechnol (2008) 14.24
Rapid nanopore discrimination between single polynucleotide molecules. Proc Natl Acad Sci U S A (2000) 8.35
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore. Proc Natl Acad Sci U S A (2009) 3.74
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection. Nat Struct Mol Biol (2004) 3.66
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution. J Am Chem Soc (2008) 3.04
Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores. Angew Chem Int Ed Engl (2005) 2.83
Electronic control of DNA polymerase binding and unbinding to single DNA molecules. ACS Nano (2009) 2.41
Discrimination of single base substitutions in a DNA strand immobilized in a biological nanopore. ACS Nano (2009) 1.76
mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc Natl Acad Sci U S A (1999) 1.60
Evidence for a tyrosine-adenine stacking interaction and for a short-lived open intermediate subsequent to initial binding of Escherichia coli RNA polymerase to promoter DNA. J Mol Biol (2008) 1.17
The potential and challenges of nanopore sequencing. Nat Biotechnol (2008) 14.24
Continuous base identification for single-molecule nanopore DNA sequencing. Nat Nanotechnol (2009) 8.09
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore. Proc Natl Acad Sci U S A (2009) 3.74
Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores. Angew Chem Int Ed Engl (2005) 2.83
Toward single molecule DNA sequencing: direct identification of ribonucleoside and deoxyribonucleoside 5'-monophosphates by using an engineered protein nanopore equipped with a molecular adapter. J Am Chem Soc (2006) 2.68
Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge. Proc Natl Acad Sci U S A (2008) 2.11
Identification of epigenetic DNA modifications with a protein nanopore. Chem Commun (Camb) (2010) 1.93
Functional bionetworks from nanoliter water droplets. J Am Chem Soc (2007) 1.81
Interactions of peptides with a protein pore. Biophys J (2005) 1.79
Formation of droplet networks that function in aqueous environments. Nat Nanotechnol (2011) 1.78
Direct transfer of membrane proteins from bacteria to planar bilayers for rapid screening by single-channel recording. Nat Chem Biol (2006) 1.77
Single-molecule observation of the catalytic subunit of cAMP-dependent protein kinase binding to an inhibitor peptide. Chem Biol (2005) 1.74
Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore. Protein Sci (2002) 1.73
Stochastic sensing of nanomolar inositol 1,4,5-trisphosphate with an engineered pore. Chem Biol (2002) 1.69
A tissue-like printed material. Science (2013) 1.66
Hybrid pore formation by directed insertion of α-haemolysin into solid-state nanopores. Nat Nanotechnol (2010) 1.65
Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore. Proc Natl Acad Sci U S A (2003) 1.62
Droplet networks with incorporated protein diodes show collective properties. Nat Nanotechnol (2009) 1.61
A primary hydrogen-deuterium isotope effect observed at the single-molecule level. Nat Chem (2010) 1.58
Protein detection by nanopores equipped with aptamers. J Am Chem Soc (2012) 1.55
Protein nanopores with covalently attached molecular adapters. J Am Chem Soc (2007) 1.55
Real-time stochastic detection of multiple neurotransmitters with a protein nanopore. ACS Nano (2012) 1.52
Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore. Nano Lett (2010) 1.51
Outer membrane protein G: Engineering a quiet pore for biosensing. Proc Natl Acad Sci U S A (2008) 1.48
Single DNA rotaxanes of a transmembrane pore protein. Angew Chem Int Ed Engl (2004) 1.48
Partitioning of individual flexible polymers into a nanoscopic protein pore. Biophys J (2003) 1.45
Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis. FEBS Lett (2008) 1.44
Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes. Nano Lett (2011) 1.42
Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc Natl Acad Sci U S A (2010) 1.41
Asymmetric droplet interface bilayers. J Am Chem Soc (2008) 1.41
Single protein pores containing molecular adapters at high temperatures. Angew Chem Int Ed Engl (2005) 1.39
Screening blockers against a potassium channel with a droplet interface bilayer array. J Am Chem Soc (2008) 1.35
Membrane protein stoichiometry determined from the step-wise photobleaching of dye-labelled subunits. Chembiochem (2007) 1.33
Multistep protein unfolding during nanopore translocation. Nat Nanotechnol (2013) 1.29
Analysis of single nucleic acid molecules with protein nanopores. Methods Enzymol (2010) 1.29
Probing distance and electrical potential within a protein pore with tethered DNA. Biophys J (2002) 1.29
A storable encapsulated bilayer chip containing a single protein nanopore. J Am Chem Soc (2007) 1.28
Stochastic detection of motor protein-RNA complexes by single-channel current recording. Chemphyschem (2007) 1.24
Kinetics of a reversible covalent-bond-forming reaction observed at the single-molecule level. Angew Chem Int Ed Engl (2002) 1.21
Stochastic detection of enantiomers. J Am Chem Soc (2006) 1.17
DNA strands from denatured duplexes are translocated through engineered protein nanopores at alkaline pH. Nano Lett (2009) 1.17
Catalyzing the translocation of polypeptides through attractive interactions. J Am Chem Soc (2007) 1.17
Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling. J Am Chem Soc (2007) 1.15
Folding of a monomeric porin, OmpG, in detergent solution. Biochemistry (2003) 1.14
Simultaneous measurement of ionic current and fluorescence from single protein pores. J Am Chem Soc (2009) 1.14
An engineered ClyA nanopore detects folded target proteins by selective external association and pore entry. Nano Lett (2012) 1.13
The leukocidin pore: evidence for an octamer with four LukF subunits and four LukS subunits alternating around a central axis. Protein Sci (2005) 1.13
Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF. Science (2013) 1.13
Temperature-responsive protein pores. J Am Chem Soc (2006) 1.10
Properties of Bacillus cereus hemolysin II: a heptameric transmembrane pore. Protein Sci (2002) 1.09
Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore. Biophys J (2010) 1.08
Single-molecule covalent chemistry with spatially separated reactants. Angew Chem Int Ed Engl (2003) 1.08
Membrane-protein structure: Piercing insights. Nature (2009) 1.07
Direct introduction of single protein channels and pores into lipid bilayers. J Am Chem Soc (2005) 1.07
Catalytic subunit of protein kinase A caged at the activating phosphothreonine. J Am Chem Soc (2002) 1.06
Individual RNA base recognition in immobilized oligonucleotides using a protein nanopore. Nano Lett (2012) 1.06
The diversity of the liquid ordered (Lo) phase of phosphatidylcholine/cholesterol membranes: a variable temperature multinuclear solid-state NMR and x-ray diffraction study. Biophys J (2006) 1.05
A genetically encoded pore for the stochastic detection of a protein kinase. Chembiochem (2006) 1.04
Nanopore-based identification of individual nucleotides for direct RNA sequencing. Nano Lett (2013) 1.04
Enhanced stability and fluidity in droplet on hydrogel bilayers for measuring membrane protein diffusion. Nano Lett (2007) 1.03
Role of the amino latch of staphylococcal alpha-hemolysin in pore formation: a co-operative interaction between the N terminus and position 217. J Biol Chem (2005) 1.03
Stochastic detection of monovalent and bivalent protein-ligand interactions. Angew Chem Int Ed Engl (2004) 1.02
Single-molecule detection of nitrogen mustards by covalent reaction within a protein nanopore. J Am Chem Soc (2008) 1.02
The internal cavity of the staphylococcal alpha-hemolysin pore accommodates approximately 175 exogenous amino acid residues. Biochemistry (2005) 1.01
Stochastic sensing of TNT with a genetically engineered pore. Chembiochem (2005) 0.98
DNA stretching and optimization of nucleobase recognition in enzymatic nanopore sequencing. Nanotechnology (2015) 0.98
Protein components for nanodevices. Curr Opin Chem Biol (2005) 0.97
Functional truncated membrane pores. Proc Natl Acad Sci U S A (2014) 0.97
Translocating kilobase RNA through the Staphylococcal α-hemolysin nanopore. Nano Lett (2013) 0.97
Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase. Biochem J (2006) 0.95
Tuning the size and properties of ClyA nanopores assisted by directed evolution. J Am Chem Soc (2013) 0.95
Rapid assembly of a multimeric membrane protein pore. Biophys J (2011) 0.95
Determining membrane capacitance by dynamic control of droplet interface bilayer area. Langmuir (2011) 0.93
Photoisomerization of an individual azobenzene molecule in water: an on-off switch triggered by light at a fixed wavelength. J Am Chem Soc (2006) 0.93
Single-molecule detection of 5-hydroxymethylcytosine in DNA through chemical modification and nanopore analysis. Angew Chem Int Ed Engl (2013) 0.93
Prepore for a breakthrough. Nat Struct Mol Biol (2005) 0.92