Published in Acta Neuropathol on May 09, 2002
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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol (2010) 6.95
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Structural basis for sorting mechanism of p62 in selective autophagy. J Biol Chem (2008) 4.20
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci U S A (2007) 3.92
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HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. J Biol Chem (2004) 2.58
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol (2008) 2.57
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). Am J Pathol (2005) 2.56
Excess peroxisomes are degraded by autophagic machinery in mammals. J Biol Chem (2005) 2.44
The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting. J Biol Chem (2003) 2.19
Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16. J Biol Chem (2005) 2.14
Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem (2004) 2.10
Reactive arthritis due to asymptomatic infection of Chlamydia trachomatis. Intern Med (2005) 2.05
Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes. J Biol Chem (2004) 2.01
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The MAP1-LC3 conjugation system is involved in lipid droplet formation. Biochem Biophys Res Commun (2009) 1.77
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Squamous cell carcinoma arising in lichen simplex chronicus. Eur J Dermatol (2010) 1.64
MAP-LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis. FASEB J (2003) 1.64
Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway. Autophagy (2006) 1.60
Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles. Autophagy (2009) 1.60
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels. Autophagy (2011) 1.59
A global analysis of bidirectional interactions in alpine plant communities shows facilitators experiencing strong reciprocal fitness costs. New Phytol (2013) 1.55
Glutamate receptor antagonists and benzodiazepine inhibit the progression of granule cell dispersion in a mouse model of mesial temporal lobe epilepsy. Epilepsia (2005) 1.53
Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. J Immunol (2003) 1.50
A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem (2009) 1.47
Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls. Autophagy (2007) 1.45
The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification. J Biol Chem (2003) 1.44
Retracted Screening and identification of a renal carcinoma specific peptide from a phage display peptide library. J Exp Clin Cancer Res (2011) 1.44
Processing and activation of lysosomal proteinases. Biol Chem (2002) 1.44
Highly efficient extraction of serum peptides by ordered mesoporous carbon. Angew Chem Int Ed Engl (2011) 1.43
Myasthenia gravis with anti-MuSK antibody, showing progressive muscular atrophy without blepharoptosis. Intern Med (2005) 1.42
Direct atomic-scale confirmation of three-phase storage mechanism in Li₄Ti₅O₁₂ anodes for room-temperature sodium-ion batteries. Nat Commun (2013) 1.41
Four subgroups of Alzheimer's disease based on patterns of atrophy using VBM and a unique pattern for early onset disease. Neuroimage (2006) 1.40
Water at DNA surfaces: ultrafast dynamics in minor groove recognition. Proc Natl Acad Sci U S A (2003) 1.40
Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease. J Exp Med (2006) 1.37
Solar wind origin in coronal funnels. Science (2005) 1.37
Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. J Biol Chem (2005) 1.36
Facilitative plant interactions and climate simultaneously drive alpine plant diversity. Ecol Lett (2013) 1.35
The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice. Transpl Immunol (2007) 1.35
Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China. Glob Chang Biol (2012) 1.35
The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers. J Mol Biol (2005) 1.34
Rheumatoid meningitis: an autopsy report and review of the literature. Clin Rheumatol (2003) 1.33
Multiple pathways of TWEAK-induced cell death. J Immunol (2002) 1.32
Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction. Neurosci Res (2006) 1.31
GATE-16 and GABARAP are authentic modifiers mediated by Apg7 and Apg3. Biochem Biophys Res Commun (2003) 1.30
Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading. Mol Cell Biol (2009) 1.27
A preliminary analysis of genome structure and composition in Gossypium hirsutum. BMC Genomics (2008) 1.26
A potential side effect of cyclosporin A: inhibition of CD4(+)CD25(+) regulatory T cells in mice. Transplantation (2006) 1.25
Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells. J Cell Biol (2007) 1.25
Pyriform spidroin 1, a novel member of the silk gene family that anchors dragline silk fibers in attachment discs of the black widow spider, Latrodectus hesperus. J Biol Chem (2009) 1.24
Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation. Hum Mol Genet (2002) 1.24
Crucial role for autophagy in degranulation of mast cells. J Allergy Clin Immunol (2011) 1.23
Proliferation of neural and neuronal progenitors after global brain ischemia in young adult macaque monkeys. Mol Cell Neurosci (2003) 1.23
Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. Biochem Biophys Res Commun (2010) 1.21
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice. Mol Cell Neurosci (2003) 1.21
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells (2002) 1.20
Comprehensive proteomics analysis of autophagy-deficient mouse liver. Biochem Biophys Res Commun (2008) 1.18
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biochem Biophys Res Commun (2010) 1.18
Enumerating treelike chemical graphs with given path frequency. J Chem Inf Model (2008) 1.18
Skeletal muscle gene expression in space-flown rats. FASEB J (2004) 1.18
Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates. Hippocampus (2003) 1.15
Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism. Blood (2010) 1.14
NGF and BDNF: from nerves to adipose tissue, from neurokines to metabokines. Riv Psichiatr (2010) 1.13
Subcellular localization of the Schlafen protein family. Biochem Biophys Res Commun (2008) 1.13
Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy. Adv Drug Deliv Rev (2012) 1.13
Atg8L/Apg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3. FEBS J (2006) 1.12
Stathmin, a new target of PRL-3 identified by proteomic methods, plays a key role in progression and metastasis of colorectal cancer. J Proteome Res (2010) 1.11
Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy (2008) 1.11
Copper(II) complexes of a series of alkoxy diazine ligands: mononuclear, dinuclear, and tetranuclear examples with structural, magnetic, and DFT studies. Inorg Chem (2004) 1.11
miR-133a represses tumour growth and metastasis in colorectal cancer by targeting LIM and SH3 protein 1 and inhibiting the MAPK pathway. Eur J Cancer (2013) 1.10
Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia. J Neurosci Res (2005) 1.09
Clinical and genetic features of familial Mediterranean fever in Japan. J Rheumatol (2009) 1.09
Screening and analysis of aconitum alkaloids and their metabolites in rat urine after oral administration of aconite roots extract using LC-TOFMS-based metabolomics. Biomed Chromatogr (2011) 1.09
Derepression of c-Fos caused by microRNA-139 down-regulation contributes to the metastasis of human hepatocellular carcinoma. Cell Biochem Funct (2012) 1.09
Mapping QTLs with epistatic effects and QTL x environment interactions for plant height using a doubled haploid population in cultivated wheat. J Genet Genomics (2008) 1.08
Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy. J Gastroenterol (2009) 1.08
Safety, tolerability, pharmacokinetics, and immunogenicity of motavizumab, a humanized, enhanced-potency monoclonal antibody for the prevention of respiratory syncytial virus infection in at-risk children. Pediatr Infect Dis J (2009) 1.08
Characterizing chaotic melodies in automatic music composition. Chaos (2010) 1.08
Overexpression of Tiam1 in hepatocellular carcinomas predicts poor prognosis of HCC patients. Int J Cancer (2009) 1.08
Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions. Biol Direct (2014) 1.08
Immunohistochemical study for O6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas. J Neurooncol (2004) 1.07
Inflammatory response and cathepsins in silica-exposed Hermansky-Pudlak syndrome model pale ear mice. Pathol Int (2004) 1.07
In vivo animal stroke models: a rationale for rodent and non-human primate models. Transl Stroke Res (2013) 1.07
t4 workshop report: Pathways of Toxicity. ALTEX (2013) 1.06
Synthesis, insecticidal activity, and structure-activity relationship of trifluoromethyl-containing phthalic acid diamide structures. J Agric Food Chem (2010) 1.06