Published in Mech Dev on June 01, 2002
Brain micro-ecologies: neural stem cell niches in the adult mammalian brain. Philos Trans R Soc Lond B Biol Sci (2008) 1.91
Involvement of Notch signaling in hippocampal synaptic plasticity. Proc Natl Acad Sci U S A (2004) 1.77
Neural stem cell self-renewal. Crit Rev Oncol Hematol (2007) 1.76
Not(ch) just development: Notch signalling in the adult brain. Nat Rev Neurosci (2011) 1.69
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68
Notch signaling in Drosophila long-term memory formation. Proc Natl Acad Sci U S A (2004) 1.63
Signaling mechanisms regulating adult neural stem cells and neurogenesis. Biochim Biophys Acta (2012) 1.50
Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron (2011) 1.49
A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49
The functional role of Notch signaling in human gliomas. Neuro Oncol (2009) 1.39
Notch1 hallmarks fibrillary depositions in sporadic Alzheimer's disease. Acta Neuropathol Commun (2016) 1.38
Transdifferentiation of mature rat hepatocytes into bile duct-like cells in vitro. Am J Pathol (2005) 1.36
Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. J Neurosci (2008) 1.32
Notch signaling regulates regeneration in the avian retina. Dev Biol (2007) 1.30
Neurogenesis in the embryonic and adult brain: same regulators, different roles. Front Cell Neurosci (2014) 1.25
Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins. J Biol Chem (2012) 1.07
Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo. J Cereb Blood Flow Metab (2009) 1.03
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs. Nat Neurosci (2012) 1.02
Dopamine systems in the forebrain. Adv Exp Med Biol (2009) 1.00
Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat Commun (2013) 0.96
Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression. J Biol Chem (2011) 0.96
Anatomical perspectives on adult neural stem cells. J Anat (2005) 0.96
Notch-1 signaling regulates microglia activation via NF-κB pathway after hypoxic exposure in vivo and in vitro. PLoS One (2013) 0.96
Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1(high) intermediate progenitors. Nat Commun (2012) 0.95
lin-12 Notch functions in the adult nervous system of C. elegans. BMC Neurosci (2005) 0.92
Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells. Cell Mol Life Sci (2013) 0.92
The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway. Stem Cells Dev (2012) 0.90
Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures. Cancer Biol Ther (2013) 0.88
Progenitors from the postnatal forebrain subventricular zone differentiate into cerebellar-like interneurons and cerebellar-specific astrocytes upon transplantation. Mol Cell Neurosci (2008) 0.87
LINS, a modulator of the WNT signaling pathway, is involved in human cognition. Orphanet J Rare Dis (2013) 0.87
BACE1 regulates hippocampal astrogenesis via the Jagged1-Notch pathway. Cell Rep (2013) 0.86
Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway. Mol Brain (2012) 0.85
Notch1 signaling modulates neuronal progenitor activity in the subventricular zone in response to aging and focal ischemia. Aging Cell (2013) 0.82
Notch signaling and neurogenesis in normal and stroke brain. Int J Physiol Pathophysiol Pharmacol (2009) 0.82
Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis. Biomed Res Int (2015) 0.81
Genome-wide significant localization for working and spatial memory: Identifying genes for psychosis using models of cognition. Am J Med Genet B Neuropsychiatr Genet (2013) 0.81
Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus. Dev Biol (2014) 0.80
Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci (2015) 0.80
Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration. Front Mol Neurosci (2016) 0.79
Notch signaling in mammalian hair cell regeneration. Trends Dev Biol (2013) 0.79
Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation. Neuro Oncol (2013) 0.79
Soluble NgR fusion protein modulates the proliferation of neural progenitor cells via the Notch pathway. Neurochem Res (2011) 0.78
Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways. Genes Dev (2015) 0.78
Notch receptor expression in neurogenic regions of the adult zebrafish brain. PLoS One (2013) 0.77
Forced notch signaling inhibits commissural axon outgrowth in the developing chick central nerve system. PLoS One (2011) 0.77
Effects of Asiatic Acid on Spatial Working Memory and Cell Proliferation in the Adult Rat Hippocampus. Nutrients (2015) 0.76
Postnatal dysregulation of Notch signal disrupts dendrite development of adult-born neurons in the hippocampus and contributes to memory impairment. Sci Rep (2016) 0.76
Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids. Front Cell Neurosci (2014) 0.76
APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins. Front Mol Neurosci (2017) 0.75
The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res (2016) 0.75
Progressive effects of N-myc deficiency on proliferation, neurogenesis, and morphogenesis in the olfactory epithelium. Dev Neurobiol (2014) 0.75
Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells. J Virol (2015) 0.75
Stepping back to move forward: a current review of iPSCs in the fight against Alzheimer's disease. Am J Stem Cells (2016) 0.75
Implication of NOTCH1 gene in susceptibility to anxiety and depression among sexual abuse victims. Transl Psychiatry (2016) 0.75
Intracerebral inoculation of mouse-passaged Saffold virus type 3 affects cerebellar development in neonatal mice. J Virol (2016) 0.75
Stimulation of adult hippocampal neurogenesis by physical exercise and enriched environment is disturbed in a CADASIL mouse model. Sci Rep (2017) 0.75
A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons. Sci Rep (2016) 0.75
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature (2012) 3.09
Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci (2009) 2.85
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science (2004) 2.82
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell (2010) 2.79
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. Nature (2012) 2.54
Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. Cell (2009) 2.53
Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood (2004) 2.44
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell (2010) 2.40
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J Cell Biol (2005) 2.32
Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A). Nat Med (2003) 2.17
Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance. Development (2004) 2.04
Dicer in Schwann cells is required for myelination and axonal integrity. J Neurosci (2010) 1.96
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci (2010) 1.93
Lineage-specific requirements of beta-catenin in neural crest development. J Cell Biol (2002) 1.87
Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells. Mol Cell Neurosci (2003) 1.84
Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease. Neuromolecular Med (2006) 1.79
RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci (2010) 1.76
Molecular mechanisms regulating myelination in the peripheral nervous system. Trends Neurosci (2011) 1.74
Notch1 is required for neuronal and glial differentiation in the cerebellum. Development (2002) 1.69
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol (2007) 1.69
HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Nat Neurosci (2011) 1.69
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68
Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell (2008) 1.67
Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol (2002) 1.65
Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination. Science (2010) 1.53
Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4. Am J Hum Genet (2007) 1.50
Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes Dev (2005) 1.50
Quantifying the early stages of remyelination following cuprizone-induced demyelination. Brain Pathol (2003) 1.47
Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module. Proc Natl Acad Sci U S A (2003) 1.46
Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease. Hum Mol Genet (2002) 1.45
Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression. Eur J Neurosci (2007) 1.45
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol (2005) 1.44
E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J (2003) 1.44
Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease). Glia (2006) 1.42
Beta-catenin-mediated cell-adhesion is vital for embryonic forebrain development. Dev Dyn (2005) 1.40
SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system. Proc Natl Acad Sci U S A (2009) 1.39
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development (2012) 1.37
Regulation of neural progenitor proliferation and survival by beta1 integrins. J Cell Sci (2005) 1.34
Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet (2002) 1.33
Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system. J Cell Biol (2009) 1.33
Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells. J Neurosci (2004) 1.33
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain (2004) 1.33
Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea. J Assoc Res Otolaryngol (2009) 1.32
Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2. Hum Mol Genet (2006) 1.30
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell (2009) 1.25
Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. J Neurosci (2011) 1.24
Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays. Stem Cells (2008) 1.24
ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury. J Neurosci (2006) 1.23
Temporal control of neural crest lineage generation by Wnt/β-catenin signaling. Development (2012) 1.22
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. J Neurosci (2006) 1.22
Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. Dev Biol (2006) 1.21
Molecular cell biology of Charcot-Marie-Tooth disease. Neurogenetics (2002) 1.17
Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination. J Neurosci (2006) 1.16
Conduction block in PMP22 deficiency. J Neurosci (2010) 1.16
The raft-associated protein MAL is required for maintenance of proper axon--glia interactions in the central nervous system. J Cell Biol (2004) 1.14
The protooncogene Ski controls Schwann cell proliferation and myelination. Neuron (2004) 1.13
Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models. Neurogenetics (2009) 1.10
Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells. Dev Biol (2002) 1.10
Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve. Glia (2011) 1.09
Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development. Mol Syst Biol (2010) 1.08
USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors. Mol Biol Cell (2009) 1.08
Early neuronal and glial fate restriction of embryonic neural stem cells. J Neurosci (2008) 1.07
Notch, epidermal growth factor receptor, and beta1-integrin pathways are coordinated in neural stem cells. J Biol Chem (2005) 1.07
Abnormal junctions and permeability of myelin in PMP22-deficient nerves. Ann Neurol (2014) 1.06
SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling. Brain (2010) 1.06
The function of RhoGTPases in axon ensheathment and myelination. Glia (2008) 1.06
An animal model for Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet (2005) 1.06
Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves. J Neurosci (2010) 1.05
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Res (2011) 1.05
Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia. Dev Neurosci (2006) 1.04
The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool. J Neurosci (2011) 1.03
Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2. Hum Mol Genet (2007) 1.02
GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance. Neurobiol Dis (2009) 1.02
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs. Nat Neurosci (2012) 1.02
E-cadherin is required for the correct formation of autotypic adherens junctions of the outer mesaxon but not for the integrity of myelinated fibers of peripheral nerves. Mol Cell Neurosci (2002) 1.01
Neurogenic subventricular zone stem/progenitor cells are Notch1-dependent in their active but not quiescent state. J Neurosci (2012) 1.01
Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom. Neurobiol Dis (2004) 0.99
Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation. Glia (2006) 0.99
Lineage analysis of quiescent regenerative stem cells in the adult brain by genetic labelling reveals spatially restricted neurogenic niches in the olfactory bulb. Eur J Neurosci (2009) 0.98
Isolation and manipulation of mammalian neural stem cells in vitro. Methods Mol Biol (2009) 0.98
Molecular diversity subdivides the adult forebrain neural stem cell population. Stem Cells (2014) 0.97
Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves. Mol Cell Neurosci (2002) 0.97
A 2-week efficacy and safety study of gaboxadol and zolpidem using electronic diaries in primary insomnia outpatients. Sleep Med (2009) 0.97
Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur J Neurosci (2008) 0.95
A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. PLoS One (2012) 0.95
The H(+) vacuolar ATPase maintains neural stem cells in the developing mouse cortex. Stem Cells Dev (2011) 0.95
Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1(high) intermediate progenitors. Nat Commun (2012) 0.95
Reelin and Notch1 cooperate in the development of the dentate gyrus. J Neurosci (2009) 0.93
The role of the Ets domain transcription factor Erm in modulating differentiation of neural crest stem cells. Dev Biol (2002) 0.93
Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis. J Neurosci (2013) 0.93
FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35. J Neurosci (2005) 0.92
Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission. EMBO Rep (2013) 0.92
Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point mutation. Neurobiol Dis (2005) 0.91