Not(ch) just development: Notch signalling in the adult brain.

Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling. Neuron (2014) 1.56

Drosophila melanogaster as a model to study drug addiction. Hum Genet (2012) 1.39

Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21. EMBO Mol Med (2013) 1.30

Adhesion in the stem cell niche: biological roles and regulation. Development (2013) 1.30

Perivascular instruction of cell genesis and fate in the adult brain. Nat Neurosci (2011) 1.27

Development and mechanism of γ-secretase modulators for Alzheimer's disease. Biochemistry (2013) 1.18

Thrombospondins as key regulators of synaptogenesis in the central nervous system. Matrix Biol (2012) 1.06

Targeting Aggressive Cancer Stem Cells in Glioblastoma. Front Oncol (2015) 1.05

Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder. Genome Biol (2014) 1.04

Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice. PLoS One (2012) 0.98

Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease. J Neurochem (2014) 0.98

Astrocyte-derived endothelin-1 inhibits remyelination through notch activation. Neuron (2014) 0.98

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons. BMC Genomics (2012) 0.96

Molecular profiles of parvalbumin-immunoreactive neurons in the superior temporal cortex in schizophrenia. J Neurogenet (2014) 0.92

Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development (2013) 0.92

Role of neural precursor cells in promoting repair following stroke. Acta Pharmacol Sin (2012) 0.91

Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signaling. J Neurosci (2013) 0.91

The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway. Stem Cells Dev (2012) 0.90

Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease. EMBO Rep (2015) 0.89

Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development (2012) 0.88

Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord. J Cell Mol Med (2014) 0.88

A specialized microvascular domain in the mouse neural stem cell niche. PLoS One (2013) 0.88

Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun (2016) 0.88

Genetic visualization of notch signaling in mammalian neurogenesis. Cell Mol Life Sci (2012) 0.87

Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons. Neuroscience (2013) 0.86

Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions. Stem Cell Reports (2014) 0.86

Age, plasticity, and homeostasis in childhood brain disorders. Neurosci Biobehav Rev (2013) 0.86

APP Receptor? To Be or Not To Be. Trends Pharmacol Sci (2016) 0.85

Adult hippocampal neurogenesis and mRNA expression are altered by perinatal arsenic exposure in mice and restored by brief exposure to enrichment. PLoS One (2013) 0.85

Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and presenilin. Exp Brain Res (2011) 0.84

Maturation and integration of adult born hippocampal neurons: signal convergence onto small Rho GTPases. Front Synaptic Neurosci (2013) 0.84

A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development. Front Neurosci (2014) 0.84

Disruption of polyubiquitin gene Ubb causes dysregulation of neural stem cell differentiation with premature gliogenesis. Sci Rep (2014) 0.83

Notch1 signaling modulates neuronal progenitor activity in the subventricular zone in response to aging and focal ischemia. Aging Cell (2013) 0.82

Regulatory System for Stem/Progenitor Cell Niches in the Adult Rodent Pituitary. Int J Mol Sci (2016) 0.82

Notch signaling in ocular vasculature development and diseases. Mol Med (2012) 0.82

Biased DNA segregation during stem cell division. Circ Res (2012) 0.82

Morphine modulates mouse hippocampal progenitor cell lineages by upregulating miR-181a level. Stem Cells (2014) 0.81

Neural progenitors, patterning and ecology in neocortical origins. Front Neuroanat (2013) 0.81

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. J Biol Chem (2012) 0.81

Notch signaling and neural connectivity. Curr Opin Genet Dev (2012) 0.81

Intraperitoneal injection of JNK-specific inhibitor SP600125 inhibits the expression of presenilin-1 and Notch signaling in mouse brain without induction of apoptosis. Brain Res (2012) 0.80

Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus. Dev Biol (2014) 0.80

Biologically targeted therapeutics in pediatric brain tumors. Pediatr Neurol (2012) 0.80

From Drosophila development to adult: clues to Notch function in long-term memory. Front Cell Neurosci (2013) 0.80

Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression. PLoS One (2016) 0.79

Genetic variants in the NOTCH4 gene influence the clinical features of migraine. J Headache Pain (2013) 0.79

Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff. Development (2016) 0.79

Estradiol meets notch signaling in developing neurons. Front Endocrinol (Lausanne) (2011) 0.79

Signals that regulate the oncogenic fate of neural stem cells and progenitors. Exp Neurol (2013) 0.79

Chronic γ-secretase inhibition reduces amyloid plaque-associated instability of pre- and postsynaptic structures. Mol Psychiatry (2013) 0.79

Presenilin-1 familial Alzheimer's disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice. Brain Behav Immun (2015) 0.78

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease. Neurosci Biobehav Rev (2016) 0.78

Forced swim test induces divergent global transcriptomic alterations in the hippocampus of high versus low novelty-seeker rats. Hum Genomics (2014) 0.78

MicroRNA profiling reveals unique miRNA signatures in IGF-1 treated embryonic striatal stem cell fate decisions in striatal neurogenesis in vitro. Biomed Res Int (2014) 0.78

Notch ligand Delta-like 1 promotes in vivo vasculogenesis in human cord blood-derived endothelial colony forming cells. Cytotherapy (2015) 0.78

Glial progenitors as targets for transformation in glioma. Adv Cancer Res (2014) 0.78

The canonical Notch pathway effector RBP-J regulates neuronal plasticity and expression of GABA transporters in hippocampal networks. Hippocampus (2015) 0.78

FLZ inhibited γ-secretase selectively and decreased Aβ mitochondrial production in APP-SH-SY5Y cells. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.78

Notch signaling in descending thoracic aortic aneurysm and dissection. PLoS One (2012) 0.78

Genome-wide copy-number variation study of psychosis in Alzheimer's disease. Transl Psychiatry (2015) 0.78

Genetics of structural connectivity and information processing in the brain. Brain Struct Funct (2016) 0.77

Canonical and Non-canonical Reelin Signaling. Front Cell Neurosci (2016) 0.77

Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway. PLoS One (2014) 0.77

Protective effect of melatonin on soluble Aβ1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. Alzheimers Res Ther (2016) 0.77

Notch Transmembrane Domain: Secondary Structure and Topology. Biochemistry (2015) 0.77

Notch Intracellular Domain (NICD) Suppresses Long-Term Memory Formation in Adult Drosophila Flies. Cell Mol Neurobiol (2015) 0.76

The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet (2015) 0.76

Notch signaling in the prostate: critical roles during development and in the hallmarks of prostate cancer biology. J Cancer Res Clin Oncol (2015) 0.76

Systems approach to the study of brain damage in the very preterm newborn. Front Syst Neurosci (2015) 0.76

Increased expression of Notch1 in temporal lobe epilepsy: animal models and clinical evidence. Neural Regen Res (2014) 0.76

Defining Single Molecular Forces Required for Notch Activation Using Nano Yoyo. Nano Lett (2016) 0.76

Notch signaling pathway is activated in motoneurons of spinal muscular atrophy. Int J Mol Sci (2013) 0.76

Chronically dysregulated NOTCH1 interactome in the dentate gyrus after traumatic brain injury. PLoS One (2017) 0.75

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons. Sci Rep (2016) 0.75

APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins. Front Mol Neurosci (2017) 0.75

Neurogenin 2 mediates amyloid-β precursor protein-stimulated neurogenesis. J Biol Chem (2014) 0.75

ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway. Oncotarget (2016) 0.75

Mechanisms of cellular plasticity in cerebral perivascular region. Prog Brain Res (2016) 0.75

Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/β-Catenin Pathway by Its GAP Domain. Front Cell Neurosci (2016) 0.75

Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis. Br J Psychiatry (2016) 0.75

Astrocyte-produced leukemia inhibitory factor expands the neural stem/progenitor pool following perinatal hypoxia-ischemia. J Neurosci Res (2016) 0.75

The Y-Box Binding Protein 1 Suppresses Alzheimer's Disease Progression in Two Animal Models. PLoS One (2015) 0.75

Large-Scale Functional RNAi Screen in C. elegans Identifies TGF-β and Notch Signaling Pathways as Modifiers of CACNA1A. ASN Neuro (2016) 0.75

Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study. JAMA Neurol (2016) 0.75

Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells. J Virol (2015) 0.75

A transposon-mediated system for flexible control of transgene expression in stem and progenitor-derived lineages. Stem Cell Reports (2015) 0.75

Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair. Front Cell Neurosci (2015) 0.75

Structural and biochemical differences between the Notch and the amyloid precursor protein transmembrane domains. Sci Adv (2017) 0.75

Genetic variants of increased waist circumference in psychosis. Psychiatr Genet (2017) 0.75

Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT-1 by a Notch-dependent mechanism. J Neurochem (2017) 0.75

Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83

The canonical Notch signaling pathway: unfolding the activation mechanism. Cell (2009) 14.72

Mechanisms and functional implications of adult neurogenesis. Cell (2008) 14.50

Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol (2006) 13.12

Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science (2004) 9.10

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci (2010) 8.09

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature (1996) 8.02

Vascular niche for adult hippocampal neurogenesis. J Comp Neurol (2000) 7.19

Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci (2009) 7.15

Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev Cell (2005) 7.07

Wnt signalling regulates adult hippocampal neurogenesis. Nature (2005) 6.66

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet (1997) 6.66

Astroglia induce neurogenesis from adult neural stem cells. Nature (2002) 6.41

For the long run: maintaining germinal niches in the adult brain. Neuron (2004) 6.01

Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat Genet (1997) 5.58

A specialized vascular niche for adult neural stem cells. Cell Stem Cell (2008) 5.53

Notch signalling regulates stem cell numbers in vitro and in vivo. Nature (2006) 5.49

In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell (2007) 5.32

Notch signalling in vertebrate neural development. Nat Rev Neurosci (2006) 4.97

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat Neurosci (2003) 3.98

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss. Nat Genet (2011) 3.97

Dll4, a novel Notch ligand expressed in arterial endothelium. Genes Dev (2000) 3.86

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol Sci (2004) 3.85

Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron (2003) 3.76

Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science (1999) 3.74

The choice of cell fate in the epidermis of Drosophila. Cell (1991) 3.71

Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nat Neurosci (2005) 3.67

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal. Nature (2010) 3.54

Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron (2008) 3.51

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development (2004) 3.30

Notch receptor activation inhibits oligodendrocyte differentiation. Neuron (1998) 3.30

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci (2007) 3.13

Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus. J Comp Neurol (2004) 3.12

Notch promotes radioresistance of glioma stem cells. Stem Cells (2010) 3.07

Cis-interactions between Notch and Delta generate mutually exclusive signalling states. Nature (2010) 3.06

A niche for adult neural stem cells. Curr Opin Genet Dev (2003) 3.05

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med (2002) 3.04

NUMB controls p53 tumour suppressor activity. Nature (2008) 2.91

Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Res (2004) 2.90

Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev Cell (2007) 2.83

Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell (2010) 2.79

Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat Neurosci (2009) 2.74

Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis. Nat Genet (2011) 2.61

The many facets of Notch ligands. Oncogene (2008) 2.57

Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci (2010) 2.55

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination. Nat Cell Biol (2006) 2.40

Numb is an endocytic protein. J Cell Biol (2000) 2.39

Oncogenic EGFR signaling networks in glioma. Sci Signal (2009) 2.38

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31

Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A (2007) 2.31

Novel research horizons for presenilins and γ-secretases in cell biology and disease. Annu Rev Cell Dev Biol (2010) 2.25

Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol (2007) 2.20

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. Proc Natl Acad Sci U S A (1999) 2.20

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A (2008) 2.17

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell (2006) 2.06

Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development (2006) 2.06

Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways. J Biol Chem (2003) 2.04

Development of neural stem cell in the adult brain. Curr Opin Neurobiol (2008) 2.02

Decision by division: making cortical maps. Trends Neurosci (2009) 1.97

cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition. Curr Biol (2009) 1.93

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proc Natl Acad Sci U S A (2008) 1.93

Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc Natl Acad Sci U S A (1999) 1.90

Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells. Neuron (2008) 1.89

Mechanistic insights into Notch receptor signaling from structural and biochemical studies. Curr Top Dev Biol (2010) 1.87

Nuclear Notch1 signaling and the regulation of dendritic development. Nat Neurosci (2000) 1.87

Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol (2010) 1.86

Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke. Nat Med (2006) 1.82

Involvement of Notch signaling in hippocampal synaptic plasticity. Proc Natl Acad Sci U S A (2004) 1.77

RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci (2010) 1.76

Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells. J Neurosci (2010) 1.72

Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68

Learning and memory deficits in Notch mutant mice. Curr Biol (2003) 1.68

Loss of notch activity in the developing central nervous system leads to increased cell death. Dev Neurosci (2006) 1.65

Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone. Nat Neurosci (2009) 1.64

Alzheimer's failure raises questions about disease-modifying strategies. Nat Rev Drug Discov (2010) 1.64

Notch signaling in Drosophila long-term memory formation. Proc Natl Acad Sci U S A (2004) 1.63

Canonical and non-canonical Notch ligands. Curr Top Dev Biol (2010) 1.62

Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nat Genet (2009) 1.62

Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity. Development (2005) 1.62

Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development (2003) 1.61

atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain. Neuron (2000) 1.58

Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo. Stem Cells (2010) 1.57

A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling. J Neurosci Res (2002) 1.56

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain. Mech Dev (2002) 1.56

FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain. Development (2009) 1.55

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev (2008) 1.54

Notch1 inhibits neurite outgrowth in postmitotic primary neurons. Neuroscience (1999) 1.54

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice. Proc Natl Acad Sci U S A (2008) 1.53

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol (2010) 1.51

Activity-dependent extrinsic regulation of adult olfactory bulb and hippocampal neurogenesis. Ann N Y Acad Sci (2009) 1.50

Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron (2011) 1.49

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proc Natl Acad Sci U S A (2002) 1.49

Notch is required for long-term memory in Drosophila. Proc Natl Acad Sci U S A (2004) 1.49

Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury. Dev Neurosci (2006) 1.48

Physical activity and the regulation of neurogenesis in the adult and aging brain. Neuromolecular Med (2008) 1.42

Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. Mol Cell Biol (2008) 1.42

Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells. Mol Cell Biochem (2007) 1.41

Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells. J Neurosci (2010) 1.41

The effects of exercise and stress on the survival and maturation of adult-generated granule cells. Hippocampus (2009) 1.39

Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell (2007) 8.99

Neurobiology of depression. Neuron (2002) 8.56

Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol (2004) 7.33

Origin of GABAergic neurons in the human neocortex. Nature (2002) 4.40

Development of the human cerebral cortex: Boulder Committee revisited. Nat Rev Neurosci (2008) 4.01

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41

Dynamic contribution of nestin-expressing stem cells to adult neurogenesis. J Neurosci (2007) 3.37

CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci U S A (2002) 3.32

Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci (2007) 3.13

Extraordinary neoteny of synaptic spines in the human prefrontal cortex. Proc Natl Acad Sci U S A (2011) 2.85

IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nat Neurosci (2006) 2.71

Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci (2007) 2.70

Molecular and morphological heterogeneity of neural precursors in the mouse neocortical proliferative zones. J Neurosci (2006) 2.49

A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A (2003) 2.47

Phosphatidylserine receptor is required for clearance of apoptotic cells. Science (2003) 2.38

Neurod1 is essential for the survival and maturation of adult-born neurons. Nat Neurosci (2009) 2.38

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31

Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A (2007) 2.31

Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (2007) 2.21

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A (2008) 2.17

IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. J Neurosci (2011) 2.15

Four-dimensional migratory coordinates of GABAergic interneurons in the developing mouse cortex. J Neurosci (2003) 2.12

Mitotic spindle rotation and mode of cell division in the developing telencephalon. Proc Natl Acad Sci U S A (2003) 2.06

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2004) 2.05

Decision by division: making cortical maps. Trends Neurosci (2009) 1.97

Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J Comp Neurol (2006) 1.96

Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci (2004) 1.94

The first neurons of the human cerebral cortex. Nat Neurosci (2006) 1.91

Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. J Neurosci (2003) 1.89

Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proc Natl Acad Sci U S A (2006) 1.86

Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area. J Neurosci (2005) 1.84

The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.78

Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells. J Neurosci (2010) 1.72

Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p. Genes Dev (2013) 1.70

Timing of neurogenesis is a determinant of olfactory circuitry. Nat Neurosci (2011) 1.67

The stumpy gene is required for mammalian ciliogenesis. Proc Natl Acad Sci U S A (2008) 1.66

Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance. Proc Natl Acad Sci U S A (2010) 1.64

Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development (2006) 1.63

Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Proc Natl Acad Sci U S A (2011) 1.60

AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biol Psychiatry (2008) 1.60

Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature (2009) 1.59

Reduction of adult hippocampal neurogenesis confers vulnerability in an animal model of cocaine addiction. J Neurosci (2010) 1.59

Cortical evolution: judge the brain by its cover. Neuron (2013) 1.54

The evolution of lineage-specific regulatory activities in the human embryonic limb. Cell (2013) 1.51

Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation. Neuropharmacology (2010) 1.50

Abnormalities of thalamic volume and shape detected in fetally irradiated rhesus monkeys with high dimensional brain mapping. Biol Psychiatry (2002) 1.50

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proc Natl Acad Sci U S A (2002) 1.49

Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia hypoxia. Cereb Cortex (2007) 1.48

Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning. Nat Med (2011) 1.47

Antibodies to cannabinoid type 1 receptor co-react with stomatin-like protein 2 in mouse brain mitochondria. Eur J Neurosci (2013) 1.45

Ascl1 (Mash1) defines cells with long-term neurogenic potential in subgranular and subventricular zones in adult mouse brain. PLoS One (2011) 1.42

Modes and mishaps of neuronal migration in the mammalian brain. J Neurosci (2008) 1.39

MEKK4 signaling regulates filamin expression and neuronal migration. Neuron (2006) 1.37

Gap junctions/hemichannels modulate interkinetic nuclear migration in the forebrain precursors. J Neurosci (2010) 1.37

Chronic morphine induces premature mitosis of proliferating cells in the adult mouse subgranular zone. J Neurosci Res (2004) 1.37

The neurogenesis hypothesis of affective and anxiety disorders: are we mistaking the scaffolding for the building? Neuropharmacology (2011) 1.36

Cdk5 is essential for adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2008) 1.34

AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization. Science (2011) 1.33

Methamphetamine self-administration and voluntary exercise have opposing effects on medial prefrontal cortex gliogenesis. J Neurosci (2007) 1.32

Everything that glitters isn't gold: a critical review of postnatal neural precursor analyses. Cell Stem Cell (2007) 1.31

Neural stem cells: historical perspective and future prospects. Neuron (2011) 1.31

Gender and endogenous levels of estradiol do not influence adult hippocampal neurogenesis in mice. Hippocampus (2007) 1.30

POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex. Cereb Cortex (2012) 1.29

Withdrawal from cocaine self-administration normalizes deficits in proliferation and enhances maturity of adult-generated hippocampal neurons. J Neurosci (2008) 1.28

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell (2012) 1.28

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind. Neurobiol Dis (2010) 1.26

Novel neuronal phenotypes from neural progenitor cells. J Neurosci (2004) 1.26

Focal cerebral ischemia induces a multilineage cytogenic response from adult subventricular zone that is predominantly gliogenic. Glia (2010) 1.23

Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development. Proc Natl Acad Sci U S A (2005) 1.22

Varied access to intravenous methamphetamine self-administration differentially alters adult hippocampal neurogenesis. Biol Psychiatry (2008) 1.21

Renewed focus on the developing human neocortex. J Anat (2010) 1.18

Dynamic expression of TrkB receptor protein on proliferating and maturing cells in the adult mouse dentate gyrus. Hippocampus (2008) 1.18

Origin, early commitment, migratory routes, and destination of cannabinoid type 1 receptor-containing interneurons. Cereb Cortex (2009) 1.17

A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss. J Neurosci (2013) 1.17

Phospholipase Cgamma in distinct regions of the ventral tegmental area differentially modulates mood-related behaviors. J Neurosci (2003) 1.15

Early serotonergic projections to Cajal-Retzius cells: relevance for cortical development. J Neurosci (2004) 1.11

JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration. J Neurochem (2008) 1.11

SPARC-like 1 regulates the terminal phase of radial glia-guided migration in the cerebral cortex. Neuron (2004) 1.09

Mixed lineage kinase-c-jun N-terminal kinase signaling pathway: a new therapeutic target in Parkinson's disease. Mov Disord (2005) 1.09

Trouble making the first move: interpreting arrested neuronal migration in the cerebral cortex. Trends Neurosci (2008) 1.08

Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends Neurosci (2009) 1.08

Different effects of bromodeoxyuridine and [3H]thymidine incorporation into DNA on cell proliferation, position, and fate. J Neurosci (2011) 1.06

Juvenile administration of methylphenidate attenuates adult hippocampal neurogenesis. Biol Psychiatry (2006) 1.05

Neuroscience: Gone with the wean. Nature (2011) 1.04

Which way does the Wnt blow? Exploring the duality of canonical Wnt signaling on cellular aging. Bioessays (2008) 1.04

Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches. BMB Rep (2009) 1.04

Combined transcriptome analysis of fetal human and mouse cerebral cortex exposed to alcohol. Proc Natl Acad Sci U S A (2011) 1.03

Exocyst is involved in polarized cell migration and cerebral cortical development. Proc Natl Acad Sci U S A (2009) 1.03

In vivo contribution of nestin- and GLAST-lineage cells to adult hippocampal neurogenesis. Hippocampus (2013) 1.02

Mouse models of Alzheimer's disease: insight into treatment. Rev Neurosci (2004) 1.02

Development and distribution of neuronal cilia in mouse neocortex. J Comp Neurol (2012) 1.01

The role of ATP signaling in the migration of intermediate neuronal progenitors to the neocortical subventricular zone. Proc Natl Acad Sci U S A (2008) 1.00