Published in Hum Mol Genet on November 15, 2002
Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras. Cancer Cell (2009) 3.37
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury. J Clin Invest (2011) 1.99
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Acad Sci U S A (2009) 1.56
Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis. J Clin Invest (2013) 1.52
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat Cell Biol (2012) 1.48
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol (2005) 1.44
Enteric neuron imbalance and proximal dysmotility in ganglionated intestine of the Sox10(Dom/+) Hirschsprung mouse model. Cell Mol Gastroenterol Hepatol (2015) 1.43
Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genet (2008) 1.41
Development and developmental disorders of the enteric nervous system. Nat Rev Gastroenterol Hepatol (2012) 1.36
An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10. BMC Dev Biol (2008) 1.31
Prospective identification and isolation of enteric nervous system progenitors using Sox2. Stem Cells (2011) 1.11
The developmental etiology and pathogenesis of Hirschsprung disease. Transl Res (2013) 1.09
Imaging neuron-glia interactions in the enteric nervous system. Front Cell Neurosci (2013) 1.08
Genetic background impacts developmental potential of enteric neural crest-derived progenitors in the Sox10Dom model of Hirschsprung disease. Hum Mol Genet (2010) 1.06
Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation. Development (2009) 1.05
Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulation. Nat Rev Genet (2015) 1.05
Isolation and live imaging of enteric progenitors based on Sox10-Histone2BVenus transgene expression. Genesis (2011) 1.02
Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol (2012) 0.99
Identification of direct regulatory targets of the transcription factor Sox10 based on function and conservation. BMC Genomics (2008) 0.92
Balancing on the crest - Evidence for disruption of the enteric ganglia via inappropriate lineage segregation and consequences for gastrointestinal function. Dev Biol (2013) 0.87
Mutations in the NRG1 gene are associated with Hirschsprung disease. Hum Genet (2011) 0.86
Origins of gliogenic stem cell populations within adult skin and bone marrow. Stem Cells Dev (2010) 0.86
Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system. J Clin Invest (2015) 0.86
Fine mapping of the NRG1 Hirschsprung's disease locus. PLoS One (2011) 0.85
SOX13 exhibits a distinct spatial and temporal expression pattern during chondrogenesis, neurogenesis, and limb development. J Histochem Cytochem (2006) 0.83
Comprehensive analysis of NRG1 common and rare variants in Hirschsprung patients. PLoS One (2012) 0.83
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma. PLoS Genet (2015) 0.81
A novel bidirectional interaction between endothelin-3 and retinoic acid in rat enteric nervous system precursors. PLoS One (2013) 0.78
Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis. Hum Mol Genet (2013) 0.78
Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open (2013) 0.77
Mouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: Old and new players. Dev Biol (2016) 0.77
Molecular fingerprinting delineates progenitor populations in the developing zebrafish enteric nervous system. Dev Dyn (2016) 0.75
A Sox10(rtTA/+) Mouse Line Allows for Inducible Gene Expression in the Auditory and Balance Organs of the Inner Ear. J Assoc Res Otolaryngol (2015) 0.75
Choices choices: regulation of precursor differentiation during enteric nervous system development. Neurogastroenterol Motil (2013) 0.75
Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System. Stem Cell Reports (2017) 0.75
Expression and function of Neuregulin 1 and its signaling system ERBB2/3 in the enteric nervous system. Front Cell Neurosci (2015) 0.75
SOX10 is over-expressed in bladder cancer and contributes to the malignant bladder cancer cell behaviors. Clin Transl Oncol (2017) 0.75
[Stem cells of the enteric nervous system: causal therapy for Hirschsprung's disease?]. Pathologe (2007) 0.75
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature (2012) 3.09
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science (2004) 2.82
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. Nature (2012) 2.54
Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. Cell (2009) 2.53
Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood (2004) 2.44
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell (2010) 2.40
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J Cell Biol (2005) 2.32
Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A). Nat Med (2003) 2.17
Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth. Cancer Res (2011) 2.08
Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance. Development (2004) 2.04
Dicer in Schwann cells is required for myelination and axonal integrity. J Neurosci (2010) 1.96
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci (2010) 1.93
Lineage-specific requirements of beta-catenin in neural crest development. J Cell Biol (2002) 1.87
Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells. Mol Cell Neurosci (2003) 1.84
Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. J Neurosci (2008) 1.81
Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease. Neuromolecular Med (2006) 1.79
Molecular mechanisms regulating myelination in the peripheral nervous system. Trends Neurosci (2011) 1.74
Notch1 is required for neuronal and glial differentiation in the cerebellum. Development (2002) 1.69
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol (2007) 1.69
HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Nat Neurosci (2011) 1.69
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68
Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell (2008) 1.67
Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol (2002) 1.65
Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain. Mech Dev (2002) 1.56
Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination. Science (2010) 1.53
Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4. Am J Hum Genet (2007) 1.50
Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes Dev (2005) 1.50
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat Cell Biol (2012) 1.48
Quantifying the early stages of remyelination following cuprizone-induced demyelination. Brain Pathol (2003) 1.47
Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module. Proc Natl Acad Sci U S A (2003) 1.46
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol (2005) 1.44
E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J (2003) 1.44
Development of the Schwann cell lineage: from the neural crest to the myelinated nerve. Glia (2008) 1.42
Wnt signaling and the regulation of stem cell function. Curr Opin Cell Biol (2004) 1.42
Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease). Glia (2006) 1.42
SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system. Proc Natl Acad Sci U S A (2009) 1.39
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development (2012) 1.37
Regulation of neural progenitor proliferation and survival by beta1 integrins. J Cell Sci (2005) 1.34
Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet (2002) 1.33
Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system. J Cell Biol (2009) 1.33
Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells. J Neurosci (2004) 1.33
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain (2004) 1.33
Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis. Differentiation (2007) 1.30
Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2. Hum Mol Genet (2006) 1.30
Neural crest progenitors and stem cells: from early development to adulthood. Dev Biol (2012) 1.29
Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis. Development (2007) 1.27
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell (2009) 1.25
Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. J Neurosci (2011) 1.24
ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury. J Neurosci (2006) 1.23
Temporal control of neural crest lineage generation by Wnt/β-catenin signaling. Development (2012) 1.22
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. J Neurosci (2006) 1.22
Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. Dev Biol (2006) 1.21
Versican V0 and V1 guide migratory neural crest cells. J Biol Chem (2006) 1.19
Probing transcription-specific outputs of β-catenin in vivo. Genes Dev (2011) 1.18
Molecular cell biology of Charcot-Marie-Tooth disease. Neurogenetics (2002) 1.17
Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination. J Neurosci (2006) 1.16
Conduction block in PMP22 deficiency. J Neurosci (2010) 1.16
Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model. Neoplasia (2011) 1.15
The raft-associated protein MAL is required for maintenance of proper axon--glia interactions in the central nervous system. J Cell Biol (2004) 1.14
Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development (2010) 1.13
The protooncogene Ski controls Schwann cell proliferation and myelination. Neuron (2004) 1.13
Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models. Neurogenetics (2009) 1.10
Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells. Dev Biol (2002) 1.10
Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve. Glia (2011) 1.09
Early neuronal and glial fate restriction of embryonic neural stem cells. J Neurosci (2008) 1.07
Abnormal junctions and permeability of myelin in PMP22-deficient nerves. Ann Neurol (2014) 1.06
An animal model for Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet (2005) 1.06
The function of RhoGTPases in axon ensheathment and myelination. Glia (2008) 1.06
SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling. Brain (2010) 1.06
Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves. J Neurosci (2010) 1.05
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Res (2011) 1.05
Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia. Dev Neurosci (2006) 1.04
The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool. J Neurosci (2011) 1.03
Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2. Hum Mol Genet (2007) 1.02
DiGeorge syndrome and pharyngeal apparatus development. Bioessays (2006) 1.02
GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance. Neurobiol Dis (2009) 1.02
The pollen tube: a soft shell with a hard core. Plant J (2012) 1.02
E-cadherin is required for the correct formation of autotypic adherens junctions of the outer mesaxon but not for the integrity of myelinated fibers of peripheral nerves. Mol Cell Neurosci (2002) 1.01
Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom. Neurobiol Dis (2004) 0.99
Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation. Glia (2006) 0.99
Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences. Cell Mol Life Sci (2012) 0.99
A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors. PLoS Genet (2013) 0.99
Ezh2 is required for neural crest-derived cartilage and bone formation. Development (2014) 0.97
Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves. Mol Cell Neurosci (2002) 0.97
Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells. Stem Cells (2011) 0.97
Testing the cancer stem cell hypothesis in melanoma: the clinics will tell. Cancer Lett (2012) 0.96
VERDANDI is a direct target of the MADS domain ovule identity complex and affects embryo sac differentiation in Arabidopsis. Plant Cell (2010) 0.95