Published in Cell on August 23, 2002
Autologous Bone Marrow Stem Cells for Children With Autism Spectrum Disorders (Autism) | NCT01740869
Intrathecal Stem Cells for Cerebral Palsy Phase II (ISCII) | NCT02231242
Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest (2004) 4.04
Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci U S A (2003) 3.52
Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain. Proc Natl Acad Sci U S A (2008) 3.44
Neocortical neurogenesis in humans is restricted to development. Proc Natl Acad Sci U S A (2006) 3.08
Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. J Clin Invest (2003) 2.81
Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex. Cereb Cortex (2009) 2.51
The stem cell potential of glia: lessons from reactive gliosis. Nat Rev Neurosci (2011) 2.49
Potential for neural regeneration after neurotoxic injury in the adult mammalian retina. Proc Natl Acad Sci U S A (2004) 2.44
Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nat Rev Neurosci (2006) 2.28
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. Proc Natl Acad Sci U S A (2004) 2.20
Evidence for neurogenesis in the adult mammalian substantia nigra. Proc Natl Acad Sci U S A (2003) 2.12
Forebrain neurogenesis after focal Ischemic and traumatic brain injury. Neurobiol Dis (2009) 2.11
Migration and differentiation of neural precursor cells can be directed by microglia. Proc Natl Acad Sci U S A (2003) 2.05
Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain. J Comp Neurol (2007) 2.02
Remodeling the brain: plastic structural brain changes produced by different motor therapies after stroke. Stroke (2008) 1.99
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci (2004) 1.94
Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut. J Clin Invest (2011) 1.88
Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury. J Clin Invest (2004) 1.85
Isolation of locally derived stem/progenitor cells from the peri-infarct area that do not migrate from the lateral ventricle after cortical stroke. Stroke (2010) 1.73
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Adult neural stem cells in the mammalian central nervous system. Cell Res (2009) 1.64
Cell migration in the normal and pathological postnatal mammalian brain. Prog Neurobiol (2009) 1.56
Neural progenitor cell survival in mouse brain can be improved by co-transplantation of helper cells expressing bFGF under doxycycline control. Exp Neurol (2013) 1.54
Stem cells for ischemic brain injury: a critical review. J Comp Neurol (2009) 1.53
Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection. Mol Neurobiol (2010) 1.51
Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc Natl Acad Sci U S A (2006) 1.50
EGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia. J Clin Invest (2003) 1.45
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Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells. Philos Trans R Soc Lond B Biol Sci (2006) 1.44
Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics. Curr Neuropharmacol (2007) 1.44
Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains. Proc Natl Acad Sci U S A (2008) 1.42
Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells. Physiol Rev (2011) 1.40
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc Natl Acad Sci U S A (2004) 1.40
Proliferation, neurogenesis and regeneration in the non-mammalian vertebrate brain. Philos Trans R Soc Lond B Biol Sci (2008) 1.38
Chronically increased transforming growth factor-beta1 strongly inhibits hippocampal neurogenesis in aged mice. Am J Pathol (2006) 1.38
The lighter side of BDNF. Am J Physiol Regul Integr Comp Physiol (2011) 1.38
alpha-Aminoadipate induces progenitor cell properties of Müller glia in adult mice. Invest Ophthalmol Vis Sci (2008) 1.37
Neurogenesis of corticospinal motor neurons extending spinal projections in adult mice. Proc Natl Acad Sci U S A (2004) 1.37
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proc Natl Acad Sci U S A (2006) 1.30
Fgfr1 is required for cortical regeneration and repair after perinatal hypoxia. J Neurosci (2009) 1.28
Role of signal transducer and activator of transcription 3 in neuronal survival and regeneration. Rev Neurosci (2008) 1.28
Effects of neuroinflammation on the regenerative capacity of brain stem cells. J Neurochem (2011) 1.27
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping. Nat Protoc (2015) 1.25
FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J Clin Invest (2003) 1.24
Regenerative response in ischemic brain restricted by p21cip1/waf1. J Exp Med (2004) 1.22
The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain. J Neural Transm (Vienna) (2009) 1.20
Selective neuronal loss in ischemic stroke and cerebrovascular disease. J Cereb Blood Flow Metab (2013) 1.19
Beta-catenin signaling increases in proliferating NG2+ progenitors and astrocytes during post-traumatic gliogenesis in the adult brain. Stem Cells (2010) 1.18
Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model. Proc Natl Acad Sci U S A (2009) 1.18
Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. PLoS One (2011) 1.17
Mechanisms and targets for angiogenic therapy after stroke. Cell Adh Migr (2009) 1.17
Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain. Front Cell Neurosci (2013) 1.17
Neonatal hypoxic/ischemic brain injury induces production of calretinin-expressing interneurons in the striatum. J Comp Neurol (2008) 1.16
EphB3 limits the expansion of neural progenitor cells in the subventricular zone by regulating p53 during homeostasis and following traumatic brain injury. Stem Cells (2010) 1.15
Multilineage potential of stable human mesenchymal stem cell line derived from fetal marrow. PLoS One (2007) 1.14
Activin in the brain modulates anxiety-related behavior and adult neurogenesis. PLoS One (2008) 1.14
Reversible neural stem cell niche dysfunction in a model of multiple sclerosis. Ann Neurol (2011) 1.12
Neural stem cells: involvement in adult neurogenesis and CNS repair. Philos Trans R Soc Lond B Biol Sci (2008) 1.12
Environmental impact on direct neuronal reprogramming in vivo in the adult brain. Nat Commun (2013) 1.11
Neurogenesis in the chronic lesions of multiple sclerosis. Brain (2008) 1.10
Effects of oxygen concentration on the proliferation and differentiation of mouse neural stem cells in vitro. Cell Mol Neurobiol (2008) 1.09
Neurogenesis and brain injury: managing a renewable resource for repair. J Clin Invest (2003) 1.08
Stem cell biology and neurodegenerative disease. Philos Trans R Soc Lond B Biol Sci (2004) 1.07
Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury. Glia (2012) 1.07
Injury and repair in developing brain. Arch Dis Child Fetal Neonatal Ed (2004) 1.06
Synaptic plasticity, neurogenesis, and functional recovery after spinal cord injury. Neuroscientist (2009) 1.06
Environmental enrichment increases progenitor cell survival in the dentate gyrus following lateral fluid percussion injury. Brain Res Mol Brain Res (2005) 1.06
Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cells. J Neurosci (2008) 1.06
Neuroprotective properties of chitosan and its derivatives. Mar Drugs (2010) 1.06
Cell therapy for stroke. NeuroRx (2004) 1.06
Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A (2004) 1.05
Neurogenesis after primary intracerebral hemorrhage in adult human brain. J Cereb Blood Flow Metab (2008) 1.04
Nestin- and doublecortin-positive cells reside in adult spinal cord meninges and participate in injury-induced parenchymal reaction. Stem Cells (2011) 1.04
Stem cells and stroke: opportunities, challenges and strategies. Expert Opin Biol Ther (2011) 1.04
Bridging the Divide between Neuroprosthetic Design, Tissue Engineering and Neurobiology. Front Neuroeng (2010) 1.03
Expression of nestin by neural cells in the adult rat and human brain. PLoS One (2011) 1.03
Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons. Proc Natl Acad Sci U S A (2004) 1.03
Vitamins E and D3 attenuate demyelination and potentiate remyelination processes of hippocampal formation of rats following local injection of ethidium bromide. Cell Mol Neurobiol (2009) 1.03
Gsx2 controls region-specific activation of neural stem cells and injury-induced neurogenesis in the adult subventricular zone. Genes Dev (2013) 1.01
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In vivo imaging of endogenous neural stem cells in the adult brain. World J Stem Cells (2015) 1.01
Electroacupuncture promotes post-stroke functional recovery via enhancing endogenous neurogenesis in mouse focal cerebral ischemia. PLoS One (2014) 1.01
Neurogenesis and neuronal commitment following ischemia in a new mouse model for neonatal stroke. Brain Res (2008) 1.00
Meninges: from protective membrane to stem cell niche. Am J Stem Cells (2012) 0.99
Behavior of neural stem cells in the Alzheimer brain. Cell Mol Life Sci (2008) 0.98
Impaired neurogenesis in adult type-2 diabetic rats. Brain Res (2008) 0.98
Evaluation of Pax6 mutant rat as a model for autism. PLoS One (2010) 0.98
Angiogenic factors stimulate growth of adult neural stem cells. PLoS One (2010) 0.98
Conditional depletion of neurogenesis inhibits long-term recovery after experimental stroke in mice. PLoS One (2012) 0.97
Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw,Ind) mice. Neurobiol Dis (2007) 0.97
Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCgamma1 activation for self-renewal of adult neural stem cells. Mol Brain (2009) 0.97
Behavior of hippocampal stem/progenitor cells following grafting into the injured aged hippocampus. J Neurosci Res (2008) 0.96
Activin A is essential for neurogenesis following neurodegeneration. Stem Cells (2009) 0.96
Long-term monitoring of post-stroke plasticity after transient cerebral ischemia in mice using in vivo and ex vivo diffusion tensor MRI. Open Neuroimag J (2007) 0.96
Reprogramming the host response in bacterial meningitis: how best to improve outcome? Clin Microbiol Rev (2003) 0.95
Adult neural stem cells: response to stroke injury and potential for therapeutic applications. Curr Stem Cell Res Ther (2011) 0.95
Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF. Gene Ther (2011) 0.95
Mucosal tolerance to E-selectin promotes the survival of newly generated neuroblasts via regulatory T-cell induction after stroke in spontaneously hypertensive rats. J Cereb Blood Flow Metab (2008) 0.95
The natural course of unruptured cerebral aneurysms in a Japanese cohort. N Engl J Med (2012) 5.57
Glial cells generate neurons: the role of the transcription factor Pax6. Nat Neurosci (2002) 3.37
Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke (2004) 3.21
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol (2004) 2.75
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol (2008) 2.57
Mash1 specifies neurons and oligodendrocytes in the postnatal brain. EMBO J (2004) 2.55
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. Curr Biol (2005) 2.53
Risk of rupture associated with intact cerebral aneurysms in the Japanese population: a systematic review of the literature from Japan. J Neurosurg (2005) 2.30
Determination of absolute protein numbers in single synapses by a GFP-based calibration technique. Nat Methods (2005) 2.20
Surgical embolectomy for large vessel occlusion of anterior circulation. Br J Neurosurg (2013) 2.11
Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion. Hum Mol Genet (2004) 2.10
Risk of hemorrhage from an arteriovenous malformation confirmed to have been obliterated on angiography after stereotactic radiosurgery. J Neurosurg (2005) 2.07
F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell (2003) 2.05
Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination. J Neurosci (2004) 2.04
SIK2 is a key regulator for neuronal survival after ischemia via TORC1-CREB. Neuron (2011) 2.03
Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines. Curr Biol (2006) 2.02
Laparoscopic liver resection of hepatocellular carcinoma. Am J Surg (2005) 2.00
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells. Hum Mol Genet (2006) 1.76
Differential control of postsynaptic density scaffolds via actin-dependent and -independent mechanisms. J Neurosci (2006) 1.76
Direct astrocytic contacts regulate local maturation of dendritic spines. J Neurosci (2007) 1.70
Blood pressure management in acute intracerebral hemorrhage: relationship between elevated blood pressure and hematoma enlargement. Stroke (2004) 1.70
ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress. Cell Metab (2008) 1.62
The Whole-genome sequencing of the obligate intracellular bacterium Orientia tsutsugamushi revealed massive gene amplification during reductive genome evolution. DNA Res (2008) 1.59
The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. J Neurosci (2007) 1.56
Development of hybrid integrated endoscope-holder system for endoscopic microneurosurgery. Neurosurgery (2004) 1.56
Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development (2007) 1.55
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss. Acta Neuropathol (2013) 1.53
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc Natl Acad Sci U S A (2006) 1.53
Presynaptically released Cbln1 induces dynamic axonal structural changes by interacting with GluD2 during cerebellar synapse formation. Neuron (2012) 1.52
Functional identification of the primary motor area by corticospinal tractography. Neurosurgery (2005) 1.52
Retrospective analysis of a 10-year experience of stereotactic radio surgery for arteriovenous malformations in children and adolescents. J Neurosurg (2002) 1.51
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Mol Biol Cell (2003) 1.48
Prolonged cardiogenic shock caused by a high-dose intravenous administration of dopamine in a patient with takotsubo cardiomyopathy. Int J Cardiol (2009) 1.46
Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development (2002) 1.46
Gamma Knife surgery for brain metastases from colorectal cancer. Clinical article. J Neurosurg (2010) 1.43
Growth factor treatment and genetic manipulation stimulate neurogenesis and oligodendrogenesis by endogenous neural progenitors in the injured adult spinal cord. J Neurosci (2006) 1.43
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Malignant transformation of a vestibular schwannoma after gamma knife radiosurgery. Lancet (2002) 1.32
Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. Dev Biol (2004) 1.23
Phylogenetic characterization of Orientia tsutsugamushi isolated in Taiwan according to the sequence homologies of 56-kDa type-specific antigen genes. Microbiol Immunol (2003) 1.21
Cross talk between notch and growth factor/cytokine signaling pathways in neural stem cells. Mol Cell Biol (2007) 1.21
Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus. Mech Dev (2003) 1.20
Ascl1 is required for oligodendrocyte development in the spinal cord. Development (2008) 1.20
Regional morphogenesis in the hypothalamus: a BMP-Tbx2 pathway coordinates fate and proliferation through Shh downregulation. Dev Cell (2006) 1.18
Reciprocal interaction with G-actin and tropomyosin is essential for aquaporin-2 trafficking. J Cell Biol (2008) 1.15
A model of global cerebral ischemia in C57 BL/6 mice. J Cereb Blood Flow Metab (2004) 1.15
The SM protein VPS-45 is required for RAB-5-dependent endocytic transport in Caenorhabditis elegans. EMBO Rep (2007) 1.15
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Laparoscopic hepatectomy for hepatocellular carcinoma in cirrhotic patients. J Hepatobiliary Pancreat Surg (2009) 1.10
Correlation of histology and molecular genetic analysis of 1p, 19q, 10q, TP53, EGFR, CDK4, and CDKN2A in 91 astrocytic and oligodendroglial tumors. Clin Cancer Res (2002) 1.10
Telencephalin slows spine maturation. J Neurosci (2006) 1.09
Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathway. J Cell Biol (2008) 1.08
Synchronized formation and remodeling of postsynaptic densities: long-term visualization of hippocampal neurons expressing postsynaptic density proteins tagged with green fluorescent protein. J Neurosci (2003) 1.08
WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum. FEBS Lett (2006) 1.08
Regulation of dendritic spine morphology by an NMDA receptor-associated Rho GTPase-activating protein, p250GAP. J Neurochem (2008) 1.07
Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning. J Neurosci (2009) 1.07
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Genome-wide gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats. J Cereb Blood Flow Metab (2004) 1.06
The dynamic organization of postsynaptic proteins: translocating molecules regulate synaptic function. Curr Opin Neurobiol (2003) 1.05
Role of the bloodstream impacting force and the local pressure elevation in the rupture of cerebral aneurysms. Stroke (2005) 1.05
Stem cell therapy for cerebral ischemia: from basic science to clinical applications. J Cereb Blood Flow Metab (2012) 1.03
Selective proteasomal dysfunction in the hippocampal CA1 region after transient forebrain ischemia. J Cereb Blood Flow Metab (2002) 1.03
Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor. Hum Mol Genet (2005) 1.03
Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation. Proc Natl Acad Sci U S A (2011) 1.03
Long-term changes of spine dynamics and microglia after transient peripheral immune response triggered by LPS in vivo. Mol Brain (2011) 1.03
Antipsychotic medication and cognitive function in schizophrenia. Schizophr Res (2006) 1.03
Downregulation of SIK2 expression promotes the melanogenic program in mice. Pigment Cell Melanoma Res (2010) 1.02
Hepatic resection using stapling devices. Am J Surg (2004) 1.02
The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure. Hum Mol Genet (2005) 1.02
Control of neurogenesis and tyrosine hydroxylase expression in neural progenitor cells through bHLH proteins and Nurr1. Exp Neurol (2006) 1.02
Gsx2 controls region-specific activation of neural stem cells and injury-induced neurogenesis in the adult subventricular zone. Genes Dev (2013) 1.01
Dephosphorylation of TORC initiates expression of the StAR gene. Mol Cell Endocrinol (2007) 1.01
Regulation of mitochondrial dynamics and distribution by synapse position and neuronal activity in the axon. Eur J Neurosci (2013) 1.01
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Ex vivo diffusion tensor imaging and neuropathological correlation in a murine model of hypoxia-ischemia-induced thrombotic stroke. J Cereb Blood Flow Metab (2010) 1.00
Complete fracture of sirolimus-eluting stent detected by multislice computed tomography. Int J Cardiol (2006) 1.00
Involvement of SIK3 in glucose and lipid homeostasis in mice. PLoS One (2012) 0.99
Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage. Circulation (2004) 0.99
Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord. Development (2005) 0.98
Signaling axis in schwann cell proliferation and differentiation. Mol Neurobiol (2006) 0.98
Naming of Rickettsiae and rickettsial diseases. Ann N Y Acad Sci (2005) 0.98
Surgical considerations for pulmonary actinomycosis. Ann Thorac Surg (2002) 0.97
Acute encephalopathy and rhabdomyolysis following rotavirus gastroenteritis. J Paediatr Child Health (2007) 0.97
Laparoscopic hepatectomy for liver tumors: proposals for standardization. J Hepatobiliary Pancreat Surg (2009) 0.96
Functional monitoring for visual pathway using real-time visual evoked potentials and optic-radiation tractography. Neurosurgery (2005) 0.96
Differences in infarct evolution between lipopolysaccharide-induced tolerant and nontolerant conditions to focal cerebral ischemia. J Neurosurg (2005) 0.96
Subdural hematoma associated with dural metastasis--case report--. Neurol Med Chir (Tokyo) (2005) 0.95
Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms. J Neurosci (2006) 0.95
Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity. Eur J Neurosci (2005) 0.95
High-purity lineage selection of embryonic stem cell-derived neurons. Stem Cells Dev (2005) 0.95
Combined use of tractography-integrated functional neuronavigation and direct fiber stimulation. J Neurosurg (2005) 0.94