Published in J Clin Invest on April 01, 2003
Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. Lancet Neurol (2009) 2.98
New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors. J Cell Biol (2005) 2.40
Forebrain neurogenesis after focal Ischemic and traumatic brain injury. Neurobiol Dis (2009) 2.11
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis. J Neurosci (2009) 1.80
The role of mineralocorticoid receptor expression in brain remodeling after cerebral ischemia. Endocrinology (2008) 1.61
Cell migration in the normal and pathological postnatal mammalian brain. Prog Neurobiol (2009) 1.56
Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model. Exp Mol Med (2008) 1.32
Regenerative response in ischemic brain restricted by p21cip1/waf1. J Exp Med (2004) 1.22
Sonic hedgehog regulates ischemia/hypoxia-induced neural progenitor proliferation. Stroke (2009) 1.21
Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain. Front Cell Neurosci (2013) 1.17
Neonatal hypoxic/ischemic brain injury induces production of calretinin-expressing interneurons in the striatum. J Comp Neurol (2008) 1.16
Neural stem cells: involvement in adult neurogenesis and CNS repair. Philos Trans R Soc Lond B Biol Sci (2008) 1.12
Circumventricular organs: a novel site of neural stem cells in the adult brain. Mol Cell Neurosci (2009) 1.08
Neurogenesis after primary intracerebral hemorrhage in adult human brain. J Cereb Blood Flow Metab (2008) 1.04
Stem cell therapy for cerebral ischemia: from basic science to clinical applications. J Cereb Blood Flow Metab (2012) 1.03
Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo. J Cereb Blood Flow Metab (2009) 1.03
Brain injury expands the numbers of neural stem cells and progenitors in the SVZ by enhancing their responsiveness to EGF. ASN Neuro (2009) 1.01
The effect of epidermal growth factor in the injured brain after trauma in rats. J Neurotrauma (2010) 0.99
Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke. Prog Neurobiol (2015) 0.99
Neural precursor cells in the ischemic brain - integration, cellular crosstalk, and consequences for stroke recovery. Front Cell Neurosci (2014) 0.98
p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions. Stem Cells (2009) 0.94
Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4. BMC Neurosci (2004) 0.94
Growth factors in ischemic stroke. J Cell Mol Med (2009) 0.94
Neurogenesis in adult human brain after traumatic brain injury. J Neurotrauma (2013) 0.94
Growth factors and stroke. NeuroRx (2006) 0.93
Role of neural precursor cells in promoting repair following stroke. Acta Pharmacol Sin (2012) 0.91
Cellular and molecular determinants of stroke-induced changes in subventricular zone cell migration. Antioxid Redox Signal (2010) 0.89
Transplantation of vascular cells derived from human embryonic stem cells contributes to vascular regeneration after stroke in mice. J Transl Med (2008) 0.87
Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model. Neurobiol Dis (2013) 0.86
Mobilization of neural stem cells and generation of new neurons in 6-OHDA-lesioned rats by intracerebroventricular infusion of liver growth factor. J Histochem Cytochem (2009) 0.86
Hydrogel-delivered brain-derived neurotrophic factor promotes tissue repair and recovery after stroke. J Cereb Blood Flow Metab (2016) 0.85
Insights into neurogenesis and aging: potential therapy for degenerative disease? Future Neurol (2010) 0.84
Regenerative therapies for central nervous system diseases: a biomaterials approach. Neuropsychopharmacology (2013) 0.84
Brain repair by cell replacement and regeneration. Proc Natl Acad Sci U S A (2003) 0.83
Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int (2014) 0.82
Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia. J Neuroinflammation (2015) 0.81
Mechanisms and Functional Significance of Stroke-Induced Neurogenesis. Front Neurosci (2015) 0.81
Strategies for regenerating striatal neurons in the adult brain by using endogenous neural stem cells. Neurol Res Int (2011) 0.79
Specific Intensity Direct Current (DC) Electric Field Improves Neural Stem Cell Migration and Enhances Differentiation towards βIII-Tubulin+ Neurons. PLoS One (2015) 0.78
Stress-induced neuroprotective effects of epiregulin and amphiregulin. PLoS One (2015) 0.78
Milk fat globule-EGF factor VIII attenuates CNS injury by promoting neural stem cell proliferation and migration after cerebral ischemia. PLoS One (2015) 0.78
The Role of the PI3K Pathway in the Regeneration of the Damaged Brain by Neural Stem Cells after Cerebral Infarction. J Clin Neurol (2015) 0.78
Traumatic Brain Injury Activation of the Adult Subventricular Zone Neurogenic Niche. Front Neurosci (2016) 0.76
Exposure to Sevoflurane Affects the Development of Parvalbumin Interneurons in the Main Olfactory Bulb in Mice. Front Neuroanat (2016) 0.75
Endogenous neural stem/progenitor cells stabilize the cortical microenvironment after traumatic brain injury. J Neurotrauma (2015) 0.75
12-Deoxyphorbols Promote Adult Neurogenesis by Inducing Neural Progenitor Cell Proliferation via PKC Activation. Int J Neuropsychopharmacol (2015) 0.75
Neurorestoration after stroke. Neurosurg Focus (2016) 0.75
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science (1992) 19.30
Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med (2002) 10.10
The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS (1988) 6.75
Astroglia induce neurogenesis from adult neural stem cells. Nature (2002) 6.41
Neurogenesis in adult subventricular zone. J Neurosci (2002) 5.22
EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron (2002) 5.06
Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell (2002) 4.87
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J Neurosci (1992) 4.60
Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci U S A (2001) 4.36
Striatal interneurones: chemical, physiological and morphological characterization. Trends Neurosci (1995) 3.65
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci (1997) 3.61
Inhibitory control of neostriatal projection neurons by GABAergic interneurons. Nat Neurosci (1999) 3.43
Regenerating the damaged central nervous system. Nature (2000) 2.85
In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J Neurosci (1996) 2.72
Adult mammalian forebrain ependymal and subependymal cells demonstrate proliferative potential, but only subependymal cells have neural stem cell characteristics. J Neurosci (1999) 2.65
Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window. Stroke (2001) 2.16
Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain. J Neurosci (1999) 2.09
Doublecortin expression in the adult rat telencephalon. Eur J Neurosci (2001) 2.03
Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc Natl Acad Sci U S A (1999) 1.90
FGF-2 regulation of neurogenesis in adult hippocampus after brain injury. Proc Natl Acad Sci U S A (2001) 1.90
In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proc Natl Acad Sci U S A (2000) 1.67
Stem cell factor stimulates neurogenesis in vitro and in vivo. J Clin Invest (2002) 1.63
Neostriatal cell subtypes and their functional roles. Neurosci Res (1997) 1.60
Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex. Neuron (1997) 1.59
Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain. Brain Res Dev Brain Res (2002) 1.48
Heparin-binding epidermal growth factor-like growth factor: hypoxia-inducible expression in vitro and stimulation of neurogenesis in vitro and in vivo. J Neurosci (2002) 1.40
Deficit of striatal parvalbumin-reactive GABAergic interneurons and decreased basal ganglia output in a genetic rodent model of idiopathic paroxysmal dystonia. J Neurosci (2000) 1.32
BMP and FGF regulate the development of EGF-responsive neural progenitor cells. Development (2000) 1.31
Neuronal calcium-binding proteins and schizophrenia. Schizophr Res (2002) 1.19
Extracellular signals that regulate the tangential migration of olfactory bulb neuronal precursors: inducers, inhibitors, and repellents. J Neurosci (2001) 1.16
What role(s) for TGFalpha in the central nervous system? Prog Neurobiol (2000) 1.13
Dopaminergic and GABAergic interneurons of the olfactory bulb are derived from the neonatal subventricular zone. Int J Dev Neurosci (1996) 1.12
Neuroprotective effect of treatment with human albumin in permanent focal cerebral ischemia: histopathology and cortical perfusion studies. Eur J Pharmacol (2001) 1.08
Neuroprotective effect of high-dose albumin therapy against global ischemic brain injury in rats. Brain Res (1999) 1.06
Intrathecal administration of epidermal growth factor and fibroblast growth factor 2 promotes ependymal proliferation and functional recovery after spinal cord injury in adult rats. J Neurotrauma (2002) 1.05
Stem cells and neuropoiesis in the adult human brain. Lancet (2002) 1.02
Proliferative zones of postnatal rat brain express epidermal growth factor receptor mRNA. Brain Res (1995) 1.00
Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-alpha mRNA in mouse brain by a quantitative nuclease protection assay. J Neurosci (1992) 1.00
Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J Cereb Blood Flow Metab (1989) 0.99
Ischemic damage in the striatum of adult gerbils: relative sparing of somatostatinergic and cholinergic interneurons contrasts with loss of efferent neurons. Exp Neurol (1990) 0.97
Transforming growth factor-alpha acting at the epidermal growth factor receptor reduces infarct volume after permanent middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab (1999) 0.91
Changes in epidermal growth factor receptor expression and competence to generate glia regulate timing and choice of differentiation in the retina. Mol Cell Neurosci (1998) 0.90
Amelioration of ischaemia-induced neuronal death in the rat striatum by NGF-secreting neural stem cells. Eur J Neurosci (1998) 0.89
Transient global ischemia in rats yields striatal projection neuron and interneuron loss resembling that in Huntington's disease. Exp Neurol (2000) 0.88
Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain. Glia (1998) 0.88
Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity. Neuroscience (1996) 0.88
Intranuclear inclusions in subtypes of striatal neurons in Huntington's disease transgenic mice. Neuroreport (1999) 0.85
Brain NGF and EGF administration improves passive avoidance response and stimulates brain precursor cells in aged male mice. Physiol Behav (2002) 0.85
Neuropathological and behavioral consequences of adeno-associated viral vector-mediated continuous intrastriatal neurotrophin delivery in a focal ischemia model in rats. Neurobiol Dis (2002) 0.83
EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum. Exp Neurol (2000) 0.82
Comparison between epidermal growth factor, transforming growth factor-alpha and EGF receptor levels in regions of adult rat brain. Brain Res Mol Brain Res (1992) 0.81
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol (2005) 11.63
Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci (2003) 6.53
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med (2002) 4.86
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci U S A (2005) 4.63
Myocardial infarction accelerates atherosclerosis. Nature (2012) 4.48
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat Med (2002) 3.17
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med (2012) 2.92
Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation. Opt Lett (2003) 2.70
Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex. J Cereb Blood Flow Metab (2004) 2.59
Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab (2005) 2.32
Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab (2007) 2.31
Suppression of cortical spreading depression in migraine prophylaxis. Ann Neurol (2006) 2.25
Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke (2005) 2.13
Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab (2008) 2.06
Cortical spreading depression activates and upregulates MMP-9. J Clin Invest (2004) 1.93
Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia. Brain (2007) 1.92
Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase. Proc Natl Acad Sci U S A (2008) 1.91
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. J Clin Invest (2008) 1.81
Rapid nongenomic actions of thyroid hormone. Proc Natl Acad Sci U S A (2006) 1.79
Pathophysiology of migraine. Annu Rev Physiol (2012) 1.73
Exciting, radical, suicidal: how brain cells die after stroke. Stroke (2005) 1.68
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. J Clin Invest (2007) 1.67
Stroke program review group: an interim report. Stroke (2008) 1.67
Targeting eNOS for stroke protection. Trends Neurosci (2004) 1.60
Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke (2008) 1.58
Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain (2007) 1.55
Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke. J Neurol Sci (2005) 1.54
Adiponectin prevents cerebral ischemic injury through endothelial nitric oxide synthase dependent mechanisms. Circulation (2007) 1.53
Migraine as an inflammatory disorder. Neurology (2005) 1.53
tPA and proteolysis in the neurovascular unit. Stroke (2004) 1.47
Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia. J Biomed Opt (2008) 1.46
Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol (2010) 1.45
Poly(ADP-ribose) polymerase-1 activity promotes NF-kappaB-driven transcription and microglial activation: implication for neurodegenerative disorders. J Neurochem (2003) 1.44
Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. Sci Signal (2009) 1.43
Endoscopic intratympanic methylprednisolone injection for treatment of refractory sudden sensorineural hearing loss and one case in pregnancy. J Otolaryngol Head Neck Surg (2010) 1.42
Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells. J Neurochem (2004) 1.41
Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells. J Immunol (2003) 1.40
Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J Cereb Blood Flow Metab (2004) 1.40
Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids. J Clin Invest (2002) 1.40
Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke. Ann N Y Acad Sci (2010) 1.39
Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation. Proc Natl Acad Sci U S A (2002) 1.36
Traumatic brain injury in mice deficient in Bid: effects on histopathology and functional outcome. J Cereb Blood Flow Metab (2006) 1.34
Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms. J Cereb Blood Flow Metab (2006) 1.32
High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia. Stroke (2010) 1.30
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts. PLoS One (2011) 1.29
Pronounced hypoperfusion during spreading depression in mouse cortex. J Cereb Blood Flow Metab (2004) 1.28
Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations. Circulation (2011) 1.28
Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A (2008) 1.28
Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice. J Cereb Blood Flow Metab (2007) 1.27
Membrane-bound L- and D-lactate dehydrogenase activities of a newly isolated Pseudomonas stutzeri strain. Appl Microbiol Biotechnol (2007) 1.27
Cell biology. PARP-1--a perpetrator of apoptotic cell death? Science (2002) 1.26
FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J Clin Invest (2003) 1.24
Regenerative response in ischemic brain restricted by p21cip1/waf1. J Exp Med (2004) 1.22
Sonic hedgehog regulates ischemia/hypoxia-induced neural progenitor proliferation. Stroke (2009) 1.21
Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases. Stroke (2003) 1.19
Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia. J Cereb Blood Flow Metab (2005) 1.18
Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts. Int J Mol Med (2007) 1.16
S1P3 receptors mediate the potent constriction of cerebral arteries by sphingosine-1-phosphate. Eur J Pharmacol (2003) 1.16
Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans. J Neurosci (2002) 1.15
Heat shock transcription factor 2 is not essential for embryonic development, fertility, or adult cognitive and psychomotor function in mice. Mol Cell Biol (2002) 1.15
Migraine aura pathophysiology: the role of blood vessels and microembolisation. Lancet Neurol (2010) 1.15
Mechanisms of pain modulation in chronic syndromes. Neurology (2002) 1.13
A rat model of studying tissue-type plasminogen activator thrombolysis in ischemic stroke with diabetes. Stroke (2011) 1.12
Enantioselective oxidation of racemic lactic acid to D-lactic acid and pyruvic acid by Pseudomonas stutzeri SDM. Bioresour Technol (2008) 1.10
New insights into migraine pathophysiology. Curr Opin Neurol (2006) 1.09
Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proc Natl Acad Sci U S A (2011) 1.08
Biotechnological routes to pyruvate production. J Biosci Bioeng (2008) 1.08
Pseudomonas stutzeri as a novel biocatalyst for pyruvate production from DL-lactate. Biotechnol Lett (2006) 1.08
STAT1 is activated in neurons after ischemia and contributes to ischemic brain injury. J Cereb Blood Flow Metab (2002) 1.08
Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. J Neurosci (2011) 1.07
Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab (2011) 1.06
Hypoxia and hypotension transform the blood flow response to cortical spreading depression from hyperemia into hypoperfusion in the rat. J Cereb Blood Flow Metab (2008) 1.06
Plasmalemma permeability and necrotic cell death phenotypes after intracerebral hemorrhage in mice. Stroke (2011) 1.06
Connectivity alterations assessed by combining fMRI and MR-compatible hand robots in chronic stroke. Neuroimage (2009) 1.05
The impact of anesthetics and hyperoxia on cortical spreading depression. Exp Neurol (2008) 1.05
Additive effects of statin and dipyridamole on cerebral blood flow and stroke protection. J Cereb Blood Flow Metab (2008) 1.00
Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice. J Cereb Blood Flow Metab (2010) 1.00
The challenge of connecting the dots in the B.R.A.I.N. Neuron (2013) 0.99
The pathophysiology of migraine: year 2005. J Headache Pain (2005) 0.98
Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. J Cereb Blood Flow Metab (2010) 0.98
Nitric oxide: considerations for the treatment of ischemic stroke. J Cereb Blood Flow Metab (2012) 0.97
MR contrast probes that trace gene transcripts for cerebral ischemia in live animals. FASEB J (2007) 0.97
Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease. Stroke (2006) 0.96
Inhibition of cerebral vasoconstriction by dantrolene and nimodipine. Neurocrit Care (2008) 0.96
Context dependent neuroprotective properties of prion protein (PrP). Prion (2009) 0.95
Chronic gliosis and behavioral deficits in mice following repetitive mild traumatic brain injury. J Neurosurg (2014) 0.95
Blood vessels, migraine, and stroke. Stroke (2007) 0.95
p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions. Stem Cells (2009) 0.94
Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice. Ann Neurol (2009) 0.93
Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke. Neuropsychopharmacology (2009) 0.93
Production of N-acetyl-D-neuraminic acid by use of an efficient spore surface display system. Appl Environ Microbiol (2011) 0.93
Therapeutic implications of central and peripheral neurologic mechanisms in migraine. Neurology (2003) 0.92