Published in Nat Immunol on September 01, 2002
Natural versus adaptive regulatory T cells. Nat Rev Immunol (2003) 8.74
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med (2003) 5.23
Interferon gamma is required for activation-induced death of T lymphocytes. J Exp Med (2002) 3.80
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med (2005) 3.70
The enemy within: keeping self-reactive T cells at bay in the periphery. Nat Rev Immunol (2002) 3.47
Response to self antigen imprints regulatory memory in tissues. Nature (2011) 2.96
T-cell costimulation--biology, therapeutic potential, and challenges. N Engl J Med (2006) 2.81
Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med (2006) 2.46
Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13
Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells. J Exp Med (2007) 1.99
Memory regulatory T cells reside in human skin. J Clin Invest (2014) 1.95
Regulatory T cells in the periphery. Immunol Rev (2006) 1.94
The initial phase of an immune response functions to activate regulatory T cells. J Immunol (2009) 1.88
Interleukin-2 in the development and control of inflammatory disease. Immunol Rev (2008) 1.83
Paths to understanding the genetic basis of autoimmune disease. Nature (2005) 1.79
Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol (2010) 1.79
A resource for the conditional ablation of microRNAs in the mouse. Cell Rep (2012) 1.66
Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity. J Immunol (2009) 1.66
CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J Immunol (2004) 1.66
The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens. Nat Immunol (2003) 1.57
IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A (2012) 1.54
Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells. J Immunol (2009) 1.52
STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms. J Immunol (2010) 1.33
Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues. J Immunol (2013) 1.29
Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen. J Exp Med (2004) 1.23
Role of B7 in T cell tolerance. J Immunol (2004) 1.21
IL-2 induces a competitive survival advantage in T lymphocytes. J Immunol (2004) 1.20
CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen. J Immunol (2002) 1.19
Functional and molecular comparison of anergic and regulatory T lymphocytes. J Immunol (2006) 1.17
Treating human autoimmunity: current practice and future prospects. Sci Transl Med (2012) 1.16
Control of CD4+ T-cell memory by cytokines and costimulators. Immunol Rev (2006) 1.14
The link between lymphocyte deficiency and autoimmunity: roles of endogenous T and B lymphocytes in tolerance. J Immunol (2005) 1.12
Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nat Immunol (2004) 1.08
Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity (2011) 1.07
CD28 signals in the immature immunological synapse. J Immunol (2004) 1.06
T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens. Immunol Rev (2005) 1.06
Duration of antigen receptor signaling determines T-cell tolerance or activation. Proc Natl Acad Sci U S A (2010) 1.05
Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. J Clin Invest (2006) 1.05
B7-independent inhibition of T cells by CTLA-4. J Immunol (2005) 1.05
Distinct roles of helper T-cell subsets in a systemic autoimmune disease. Blood (2008) 1.04
Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. J Immunol (2008) 0.94
Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia. J Immunol (2007) 0.94
A converse 4-1BB and CD40 ligand expression pattern delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg. J Immunol (2012) 0.93
Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues. J Immunol (2014) 0.92
Constitutive expression of B7-1 on B cells uncovers autoimmunity toward the B cell compartment in the nonobese diabetic mouse. J Immunol (2007) 0.91
Role of T cells in a murine model of Escherichia coli sepsis. Eur J Immunol (2007) 0.91
The life of regulatory T cells. Ann N Y Acad Sci (2013) 0.88
Mechanisms of human autoimmunity. J Clin Invest (2015) 0.87
Revisiting the role of IL-2 in autoimmunity. Eur J Immunol (2010) 0.87
Balance of Th1 and Th17 effector and peripheral regulatory T cells. Microbes Infect (2009) 0.87
Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine (2011) 0.82
IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells. PLoS One (2012) 0.81
Differential requirements for Th1 and Th17 responses to a systemic self-antigen. J Immunol (2011) 0.81
Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity (2009) 0.77
Dendritic cells giveth and taketh away. Nat Immunol (2005) 0.77
Functional tolerance is maintained despite proliferation of CD4 T cells after encounter with tissue-derived antigen. Dev Immunol (2002) 0.75
A network of regulatory pathways in lepromatous leprosy. Clin Immunol (2011) 0.75
Retraction. Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes. Immunity (2009) 0.75
Retraction. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity (2009) 0.75
Pillars article: antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. 1984. J Immunol (2007) 0.75