Published in Immunol Rev on December 01, 2008
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. Nature (2012) 3.85
CISH and susceptibility to infectious diseases. N Engl J Med (2010) 3.31
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family. Immunol Rev (2011) 2.54
Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol (2010) 1.79
Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease. World J Gastroenterol (2009) 1.33
Treatment of allergic asthma: modulation of Th2 cells and their responses. Respir Res (2011) 1.31
STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of Class O Forkhead transcription factors. J Biol Chem (2011) 1.22
A role for IL-27 in limiting T regulatory cell populations. J Immunol (2011) 1.17
Regulation of CD4+ T-cell contraction during pathogen challenge. Immunol Rev (2010) 1.14
Salivary markers of inflammation in response to acute stress. Brain Behav Immun (2014) 1.06
MiR-146a and NF-κB1 regulate mast cell survival and T lymphocyte differentiation. Mol Cell Biol (2012) 1.03
Caffey disease: new perspectives on old questions. Bone (2013) 1.02
T cells in ANCA-associated vasculitis: what can we learn from lesional versus circulating T cells? Arthritis Res Ther (2010) 1.02
Ligand deconstruction: Why some fragment binding positions are conserved and others are not. Proc Natl Acad Sci U S A (2015) 1.00
In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome. J Infect Dis (2011) 1.00
Deficiency of endothelial heparan sulfates attenuates allergic airway inflammation. J Immunol (2009) 1.00
Notch controls the magnitude of T helper cell responses by promoting cellular longevity. Proc Natl Acad Sci U S A (2012) 0.99
Reciprocal granzyme/perforin-mediated death of human regulatory and responder T cells is regulated by interleukin-2 (IL-2). J Mol Med (Berl) (2010) 0.97
Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02(A) candidate tuberculosis vaccine in purified protein derivative-negative adults. Clin Vaccine Immunol (2010) 0.96
Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization. J Immunol (2010) 0.94
Nucleotide-binding and oligomerization domain-like receptors and retinoic acid inducible gene-like receptors in human tonsillar T lymphocytes. Immunology (2011) 0.92
Three-Dimensional Gradients of Cytokine Signaling between T Cells. PLoS Comput Biol (2015) 0.90
Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum (2011) 0.89
Immunotoxicology of arc welding fume: worker and experimental animal studies. J Immunotoxicol (2012) 0.88
Tregs and infections: on the potential value of modifying their function. J Leukoc Biol (2011) 0.88
Sedative drug modulates T-cell and lymphocyte function-associated antigen-1 function. Anesth Analg (2011) 0.86
Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes. Chin Med (2011) 0.84
Estrogen alters baseline and inflammatory-induced cytokine levels independent from hypothalamic-pituitary-adrenal axis activity. Cytokine (2015) 0.82
Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat. PLoS One (2010) 0.82
Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine (2011) 0.82
Pituitary adenylate cyclase activating peptide deficient mice exhibit impaired thymic and extrathymic regulatory T cell proliferation during EAE. PLoS One (2013) 0.81
Multiple linked quantitative trait loci within the Tmevd2/Eae3 interval control the severity of experimental allergic encephalomyelitis in DBA/2J mice. Genes Immun (2010) 0.81
Fine epitope specificity of antibodies against interleukin-2 explains their paradoxical immunomodulatory effects. MAbs (2013) 0.81
Immunotherapeutic strategies in autoimmune uveitis. Autoimmun Rev (2014) 0.80
Indoleamine 2,3-dioxygenase and metabolites protect murine lung allografts and impair the calcium mobilization of T cells. Am J Respir Cell Mol Biol (2012) 0.79
Lymphocyte glucose and glutamine metabolism as targets of the anti-inflammatory and immunomodulatory effects of exercise. Mediators Inflamm (2014) 0.79
Acute exhaustive exercise regulates IL-2, IL-4 and MyoD in skeletal muscle but not adipose tissue in rats. Lipids Health Dis (2011) 0.79
Comparative analysis of activation phenotype, proliferation, and IFN-gamma production by spleen NK1.1(+) and NK1.1(-) T cells during Plasmodium chabaudi AS malaria. J Interferon Cytokine Res (2010) 0.78
Aberrant production of Th1/Th2/Th17-related cytokines in serum of C57BL/6 mice after short-term formaldehyde exposure. Int J Environ Res Public Health (2014) 0.78
Imaging of inflamed carotid artery atherosclerotic plaques with the use of 99mTc-HYNIC-IL-2 scintigraphy in end-stage renal disease patients. Eur J Nucl Med Mol Imaging (2012) 0.78
Anti-IL-2 treatment impairs the expansion of T(reg) cell population during acute malaria and enhances the Th1 cell response at the chronic disease. PLoS One (2012) 0.77
The 4q27 locus and prostate cancer risk. BMC Cancer (2010) 0.76
Angiotensin and systems thinking: wrapping your mind around the big picture. Ochsner J (2013) 0.76
Molecular and Cellular Characterization of Human CD8 T Suppressor Cells. Front Immunol (2016) 0.76
IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling study. BMC Syst Biol (2016) 0.75
Loureirin B, an essential component of Sanguis Draxonis, inhibits Kv1.3 channel and suppresses cytokine release from Jurkat T cells. Cell Biosci (2014) 0.75
New Approaches to the Immunotherapy of Type 1 Diabetes Mellitus Using Interleukin-27. Adv Pharm Bull (2015) 0.75
Clinical Potential of Regulatory T Cell Therapy in Liver Diseases: An Overview and Current Perspectives. Front Immunol (2016) 0.75
Dendritic Cell KLF2 Expression Regulates T Cell Activation and Proatherogenic Immune Responses. J Immunol (2016) 0.75
Multifunctional T Cell Response to DosR and Rpf Antigens Is Associated with Protection in Long-Term Mycobacterium tuberculosis-Infected Individuals in Colombia. Clin Vaccine Immunol (2016) 0.75
Modulation of Tim-3 Expression by Antigen-Dependent and -Independent Factors on T Cells from Patients with Chronic Hepatitis B Virus Infection. Front Cell Infect Microbiol (2017) 0.75
A corticoid-sensitive cytokine release assay for monitoring stress-mediated immune modulation. Clin Exp Immunol (2013) 0.75
Interleukin-2 modulatory effects on the functional activity of human mononuclear cells in vitro. Dokl Biol Sci (2010) 0.75
Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia. Blood (2017) 0.75
Natural versus adaptive regulatory T cells. Nat Rev Immunol (2003) 8.74
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med (2003) 5.23
Macrophages: master regulators of inflammation and fibrosis. Semin Liver Dis (2010) 4.24
Interferon gamma is required for activation-induced death of T lymphocytes. J Exp Med (2002) 3.80
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med (2005) 3.70
The enemy within: keeping self-reactive T cells at bay in the periphery. Nat Rev Immunol (2002) 3.47
Response to self antigen imprints regulatory memory in tissues. Nature (2011) 2.96
T-cell costimulation--biology, therapeutic potential, and challenges. N Engl J Med (2006) 2.81
Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med (2006) 2.46
Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13
Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells. J Exp Med (2007) 1.99
Memory regulatory T cells reside in human skin. J Clin Invest (2014) 1.95
Regulatory T cells in the periphery. Immunol Rev (2006) 1.94
Muc5ac: a critical component mediating the rejection of enteric nematodes. J Exp Med (2011) 1.88
The initial phase of an immune response functions to activate regulatory T cells. J Immunol (2009) 1.88
Paths to understanding the genetic basis of autoimmune disease. Nature (2005) 1.79
Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol (2010) 1.79
A resource for the conditional ablation of microRNAs in the mouse. Cell Rep (2012) 1.66
Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity. J Immunol (2009) 1.66
CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J Immunol (2004) 1.66
The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens. Nat Immunol (2003) 1.57
IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A (2012) 1.54
Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells. J Immunol (2009) 1.52
STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms. J Immunol (2010) 1.33
Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues. J Immunol (2013) 1.29
Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen. J Exp Med (2004) 1.23
Role of B7 in T cell tolerance. J Immunol (2004) 1.21
IL-2 induces a competitive survival advantage in T lymphocytes. J Immunol (2004) 1.20
CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen. J Immunol (2002) 1.19
Functional and molecular comparison of anergic and regulatory T lymphocytes. J Immunol (2006) 1.17
Treating human autoimmunity: current practice and future prospects. Sci Transl Med (2012) 1.16
Control of CD4+ T-cell memory by cytokines and costimulators. Immunol Rev (2006) 1.14
The link between lymphocyte deficiency and autoimmunity: roles of endogenous T and B lymphocytes in tolerance. J Immunol (2005) 1.12
Quantitative assessment of macrophage functions in repair and fibrosis. Curr Protoc Immunol (2011) 1.10
Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nat Immunol (2004) 1.08
Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity (2011) 1.07
CD28 signals in the immature immunological synapse. J Immunol (2004) 1.06
T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens. Immunol Rev (2005) 1.06
Duration of antigen receptor signaling determines T-cell tolerance or activation. Proc Natl Acad Sci U S A (2010) 1.05
B7-independent inhibition of T cells by CTLA-4. J Immunol (2005) 1.05
Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. J Clin Invest (2006) 1.05
Distinct roles of helper T-cell subsets in a systemic autoimmune disease. Blood (2008) 1.04
Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. J Immunol (2008) 0.94
Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia. J Immunol (2007) 0.94
A converse 4-1BB and CD40 ligand expression pattern delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg. J Immunol (2012) 0.93
Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues. J Immunol (2014) 0.92
Constitutive expression of B7-1 on B cells uncovers autoimmunity toward the B cell compartment in the nonobese diabetic mouse. J Immunol (2007) 0.91
Role of T cells in a murine model of Escherichia coli sepsis. Eur J Immunol (2007) 0.91
The life of regulatory T cells. Ann N Y Acad Sci (2013) 0.88
Mechanisms of human autoimmunity. J Clin Invest (2015) 0.87
Revisiting the role of IL-2 in autoimmunity. Eur J Immunol (2010) 0.87
Balance of Th1 and Th17 effector and peripheral regulatory T cells. Microbes Infect (2009) 0.87
Life and death in effector T cells. Nat Immunol (2002) 0.82
Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine (2011) 0.82
A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity. PLoS Pathog (2013) 0.82
IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells. PLoS One (2012) 0.81
Differential requirements for Th1 and Th17 responses to a systemic self-antigen. J Immunol (2011) 0.81
Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity (2009) 0.77
Dendritic cells giveth and taketh away. Nat Immunol (2005) 0.77
A network of regulatory pathways in lepromatous leprosy. Clin Immunol (2011) 0.75
Functional tolerance is maintained despite proliferation of CD4 T cells after encounter with tissue-derived antigen. Dev Immunol (2002) 0.75
Retraction. Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes. Immunity (2009) 0.75
Pillars article: antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. 1984. J Immunol (2007) 0.75
Retraction. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity (2009) 0.75